Characterization of aggregate size in Taxus suspension cell culture

Plant Cell Reports

Volumn 29, Issue 5, 2010, Pages 485-494

  Kolewe, Martin E ^a   Henson, Michael A ^a   Roberts, Susan C ^a  

^a University of Massachusetts   (United States)

Author keywords

Bioprocess characterization; Coulter counter; Paclitaxel; Plant cell aggregates; Plant cell culture; Taxus

Indexed keywords

ARTICLE; BIOMASS; CELL AGGREGATION; CELL COUNT; CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; FILTRATION; IMPEDANCE; METHODOLOGY; TAXUS;

BIOMASS; CELL AGGREGATION; CELL COUNT; CELL CULTURE TECHNIQUES; CELLS, CULTURED; ELECTRIC IMPEDANCE; FILTRATION; TAXUS;

TAXUS;

EID: 77952420580     PISSN: 07217714     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00299-010-0837-5     Document Type: Article

References (23)

1. Bolta Z, Baricevic D, Raspor P (2003) Biomass segregation in sage cell suspension culture. Biotechnol Lett 25: 61-65.
2. Edahiro J, Seki M (2006) Phenylpropanoid metabolite supports cell aggregate formation in strawberry cell suspension culture. J Biosci Bioeng 102: 8-13.
3. Forni C, Frattarelli A, Damiano C (1999) Different size, shape and growth behavior of cells in suspension cultures of strawberry (Fragaria × ananassa Duch.). Plant Biosyst 133: 205-212.
4. Georgiev MI, Weber J, Maciuk A (2009) Bioprocessing of plant cell cultures for mass production of targeted compounds. Appl Microbiol Biot 83: 809-823.
5. Graham MD (2003) The Coulter principle: foundation of an industry. J Assoc Lab Autom 8: 72-81.
6. Hulst AC, Meyer MT, Breteler H, Tramper J (1989) Effect of aggregate size in cell cultures of Tagetes petula on thiophene production and cell growth. Appl Microbiol Biotechnol 30: 18-25.
7. Keßler M, ten Hoopen HJG, Furusaki S (1999) The effect of the aggregate size on the production of ajmalicine and tryptamine in Catharanthus roseus suspension culture. Enzyme Microb Technol 24: 308-315.
8. Kolewe ME, Gaurav V, Roberts SC (2008) Pharmaceutically active natural product synthesis and supply via plant cell culture technology. Mol Pharm 5: 243-256.
9. Kubek DJ, Shuler ML (1978) Electronic measurement of plant cell number and size in suspension culture. J Exp Bot 29: 511-523.
10. Kubitschek HE (1958) Electronic counting and sizing of bacteria. Nature 182: 234-235.
11. Kubitschek HE (1969) Counting and sizing micro-organisms with the Coulter counter. In: Norris R, Ribbons DW (eds) Methods in microbiology, vol 1. Academic Press, NY, pp 593-610.
12. Kwok KH, Tsoulpha P, Doran PM (1992) Limitations associated with conductivity measurement for monitoring growth in plant-tissue culture. Plant Cell Tiss Org Cult 29: 93-99.
13. Madhusudhan R, Ravishankar GA (1996) Gradient of anthocyanin in cell aggregates of Daucus carota in suspension cultures. Biotechnol Lett 18: 1253-1256.
14. Mavituna F, Park JM (1987) Size distribution of plant cell aggregates in batch culture. Chem Eng J 35: B9-B14.
15. McDonald KA, Jackman AP, Hurst S (2001) Characterization of plant suspension cultures using the focused beam reflectance technique. Biotechnol Lett 23: 317-324.
16. Naill MC, Roberts SC (2004) Preparation of single cells from aggregated Taxus suspension cultures for population analysis. Biotechnol Bioeng 86: 817-826.
17. Naill MC, Roberts SC (2005a) Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnol Bioeng 90: 491-500.
18. Naill MC, Roberts SC (2005b) Flow cytometric identification of paclitaxel-accumulating subpopulations. Biotechnol Prog 21: 978-983.
19. Pepin MF, Smith MAL, Reid JF (1999) Application of imaging tools to plant cell culture: relationship between plant cell aggregation and flavonoid production. In Vitro Cell Dev Plant 35: 290-295.
20. Rodriguez-Monroy M, Trejo-Espino JL, Jimenez-Aparicio A, Morante ML, Villarreal ML, Trejo-Tapia G (2004) Evaluation of morphological properties of Solanum chrysotrichum cell cultures in a shake flask and fermentor and rheological properties of broths. Food Technol Biotechnol 42: 153-158.
21. Ryu DDY, Lee SO, Romani RJ (1990) Determination of growth rate for plant cell cultures: comparative studies. Biotechnol Bioeng 35: 305-311.
22. Trejo-Tapia G, Hernandez-Trujillo R, Trejo-Espino JL, Jimenez-Aparacio A, Rodriguez-Monroy M (2003) Analysis of morphological characteristics of Solanum chrysotrichum cell suspension cultures. World J Microb Biotechnol 19: 929-932.
23. Zhao D, Huang Y, Jin Z, Qu W, Lu D (2003) Effect of aggregate size in cell cultures of Saussurea medusa on cell growth and jaceosidin production. Plant Cell Rep 21: 1129-1133.