Flow cytometric identification of paclitaxel-accumulating subpopulations

Biotechnology Progress

Volumn 21, Issue 3, 2005, Pages 978-983

  Naill, Michael C ^a   Roberts, Susan C ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; FLOW MEASUREMENT; FLUORESCENCE; OPTICAL MICROSCOPY; POPULATION STATISTICS;

CELL-TO-CELL VARIATION; FLOW CYTOMETRY; IMMUNOFLUORESCENCE; PROTOPLASTS;

PLANT CELL CULTURE;

PACLITAXEL;

ARTICLE; CELL CULTURE; CULTURE TECHNIQUE; CYTOLOGY; EVALUATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; METHODOLOGY; SPECTROFLUOROMETRY; TAXUS;

CELL CULTURE TECHNIQUES; CELLS, CULTURED; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; MICROSCOPY, FLUORESCENCE; PACLITAXEL; SPECTROMETRY, FLUORESCENCE; TAXUS;

CUSPIDATA; TAXUS; TAXUS CUSPIDATA;

EID: 20344382088     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp049544l     Document Type: Article

References (36)

1. Roberts, S.; Shuler, M. Large-scale plant cell culture. Curr. Opin. Biotechnol. 1997, 8, 154-159.
2. Ketchum, R.; Gibson, D. Paclitaxel production in suspension cell cultures of Taxus. Plant Cell Tiss. Org. Cult. 1996, 46, 9-16.
3. Ketchum, R.; Gibson, D.; Croteau, R.; Shuler, M. The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate. Biotechnol. Bioeng. 1999, 62 (1), 97-105.
4. Brown, S.; Renaudin, J. P.; Prevot, C.; J., G. Flow cytometry and sorting of plant protoplasts: technical problems and physiological results from a study of pH and alkaloids in Catharanthus roseus. Physiol. Veg. 1984, 22, 541-544.
5. Ellis, B. Cell to cell variability in secondary metabolite production within cultured plant cell populations. In Plant Tissue Culture; Fujiwara, A., Ed.; IAPTC: Tokyo, 1982; pp 395-396.
6. Hall, R.; Yeoman, M. Temporal and spatial heterogeneity in the accumulation of anthocyanins in cell cultures of Catharanthus roseus. J. Exp. Bot. 1986, 37, 48-60.
7. Hall, R.; Yeoman, M. Intercellular and intercultural heterogeneity in secondary metabolite accumulation in cultures of Catharanthus roseus following cell line selection. J. Exp. Bot. 1987, 38, 1391-1398.
8. Hara, Y.; Yamagata H.; Morimoto T.; Hiratsuka J.; Yoshioka T.; Fujita Y.; Y., Y. Flow cytometric analysis of cellular berberine contents in high and low producing cell lines of Coptis japonica obtained by repeated selection. Planta. Med. 1989, 55, 151-154.
9. Sato, F.; Yamada, Y. High berberine-producing cultures of Coptis japonica cells. Phytochemistry 1984, 23, 281-285.
10. Sakamoto, K.; Iida, K.; Koyano, T.; Asada, Y.; Furuya, T. Method for selecting anthocyanin producing cells by a cell sorter. Planta Med. 1994, 60, 253-259.
11. Yanpaisan, W.; King, N.; Doran, P. Analysis of cell cycle activity and population dynamics in heterogeneous plant cell suspensions using flow cytometry. Biotechnol. Bioeng. 1998, 58, 515-528.
12. Naill, M.; Roberts, S. Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnol. Bioeng. 2005, 90, 491-500.
13. Davey, H.; Kell, D. Flow cytometry and cell sorting of heterogeneous microbial populations: the importance of single cell analyses. Microbiol. Rev. 1996, 60 (4), 641-696.
14. Shapiro, H. Practical Flow Cytometry; Hoboken, N. J., Ed.; John Wiley & Sons: New York, 2003.
15. Yanpaisan, W.; King, N.; Doran, P. Flow cytometry of plant cells with applications in large-scale bioprocessing. Biotechnol. Adv. 1999, 17, 3-27.
16. Azuma, T.; Harrison, G.; Demain, A. Isolation of a gramicidin S hyperproducing strain of Bacillus brevis by use of a FACS system. Appl. Microbiol. Biotechnol. 1992, 38, 173-178.
17. Naill, M.; Roberts, S. Flow cytometric analysis of protein content in Taxus protoplasts and single cells as compared to aggregated suspension cultures. Plant Cell Rep. 2005, 23, 528-533.
18. Kawamura, M.; Shigeoka, T.; Tahara, M.; Takami, M.; Ohashi, H.; Akita, M.; Kobayashi, Y.; Sakamoto, T. Efficient selection of cells with high taxol content from heterogeneous Taxus cell suspensions by magnetic or fluorescent antibodies. J. Soc. Ferment. Bioeng. 1998, 76, 3-7.
19. Naill, M.; Roberts, S. Preparation of isolated cells from Taxus supension cultures for population analysis. Biotechnol. Bioeng. 2004, 86, 817-826.
20. Roberts, S.; Naill, M.; Gibson, D.; Shuler, M. A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes. Plant Cell Rep. 2003, 21 (12), 1217-1220.
21. Aoyagi, H.; DiCosmo, F.; Tanaka, H. Efficient paclitaxel production using protoplasts isolated from cultured cells of Taxus cuspidata. Planta Med. 2002, 68, 420-424.
22. Gundlach, H.; Muller, M.; Kutchan, T.; Zenk, M. Jasmonic acid is a signal transducer in elicitor-induced plant cell cultures. Proc. Natl. Acad. Sci. U.S.A. 1992, 89, 2389-2393.
23. Mirjalili, N.; Linden, J. Methyl jasmonate induced production of Taxol in suspension cultures of Taxus cuspidata. Biotechnol Bioeng. 1996, 12, 110-118.
24. Yukimune, Y.; Tabata, H.; Higashi, Y.; Hara, Y. Methyl jasmonate-induced overproduction of paclitaxel and baccatin III in Taxus cell suspension cultures. Nat. Biotechnol. 1996, 14, 1129-1132.
25. Wang, Y.; Yuan, Y.; Wu, J. Induction studies of methyl jasmonate and salicylic acid on taxane production in suspension cultures of Taxus chinensis var. mairei. Biochem. Eng. J. 2004, 19 (3), 259-265.
26. Wu, J.; Lin, L. Enhancement of taxol production and release in Taxus chinensis cell cultures by ultrasound, methyl jasmonate and in situ solvent extraction. Appl. Microbiol. Biotechnol. 2003, 62 (2-3), 151-155.
27. Wang, X.; Yuan, Y.; Li, J.; Wu, J.; Yang, W. Biological changes in suspension cultures of Taxus cuspidata induced by dimethyl sulfoxide and ethanol. J. Mol. Catal. B: Enzym. 2002, 18, 211-217.
28. Dong, H.; Zhong, J. Significant improvement of taxane production in suspension cultures of Taxus chinensis by combining elicitation with sucrose feed. Biochem. Eng. J. 2001, 8 (2), 145-150.
29. Baebler, S.; Camloh, M.; Kovac, M.; Ravnikar, M.; Zel, J. Jasmonic acid stimulates taxane production in cell suspension culture of yew (Taxus x media). Planta Med. 2002, 68 (5), 475-476.
30. Ciddi, V.; Srinivasan, V.; Shuler, M. Elicitation of Taxus sp. cell cultures for production of Taxol. Biotechnol Lett. 1995, 17, 1343-1346.
31. Choi, H.; Kim, S.; Song, J.; Son, J.; Hong, S.; Durzan, D.; Lee, H. Localization of paclitaxel in suspension cultures of Taxus chinensis. J. Microbiol. Biotechnol. 2001, 11 (3), 458-462.
32. Russin, W.; Ellis, D.; Gottwald, J.; Zeldin, E.; Brodhagen, M.; Evert, R. Immunocytochemical localization of Taxol in Taxus cuspidata. Int. J. Plant Sci. 1995, 156 (5), 668-678.
33. Grothaus, P.; Bignami, G.; O'Malley, S.; Harada, K.; Byrnes, J.; Waller, D.; Raybould, T. Taxane-specific monoclonal antibodies: measurement of taxol, baccatin III, and "total taxanes" in Taxus brevifolia extracts by enzyme immunoassay. J. Nat. Prod. 1995, 58 (7), 1003-1014.
34. Durrant, W.; Rowland, O.; Piedras, P.; Hammond-Kosack, K.; Jones, J. cDNA-AFLP reveals a striking overlap in race-specific resistance and wound response gene expression profiles. Plant Cell 2000, 12, 963-977.
35. Franke, J.; Bohm, H. Accumulation and excretion of alkaloids by Macleaya microcarpa cell cultures. I. Experiments on liquid medium. Biochem. Physiol. Pflanz. 1982, 177, 501-507.
36. Boitelconti, M.; Gontier, E.; Laberche, J. C.; Ducrocq, C.; Sangwannorreel, B. S. Permeabilization of Datura-Innoxia hairy roots for release of stored tropane alkaloids. Planta Med. 1995, 61 (3), 287-290.