Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 17, 2010, Pages 7869-7874

  Lukin, Kara ^a   Fields, Scott ^a   Lopez, Desiree ^a   Cherrier, Marie ^b   Ternyak, Kristina ^a   Ramírez, Julita ^a   Feeney, Ann J ^b   Hagman, James ^a  

^a DEPARTMENT OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

B cell development; B lymphopoiesis; Immunoglobulin gene rearrangements; Transcription factor dosage; Transcriptional networks

Indexed keywords

CD2 ANTIGEN; EARLY B CELL FACTOR 1 PROTEIN; IMMUNOGLOBULIN; INTERLEUKIN 2 RECEPTOR ALPHA; PROTEIN; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL LINEAGE; GENE EXPRESSION; GENE REARRANGEMENT; GENETIC TRANSCRIPTION; HAPLOTYPE; HEAVY CHAIN; LIGHT CHAIN; MOUSE; NONHUMAN; PLASMACYTOMA; PRIORITY JOURNAL; SURFACE PROPERTY;

ANIMALS; ANTIGENS, CD2; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA PRIMERS; FLOW CYTOMETRY; GENE DOSAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANS-ACTIVATORS;

MUS;

EID: 77952414175     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1003525107     Document Type: Article

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