Evidence for copper-dioxygen reactivity during α-synuclein fibril formation

Journal of the American Chemical Society

Volumn 132, Issue 19, 2010, Pages 6636-6637

  Lucas, Heather R ^a,b   Debeer, Serena ^c   Hong, Myoung Soon ^a,b   Lee, Jennifer C ^a,b  

^a National Heart Lung and Blood Institute   (China)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID FORMATION; AUTOREDUCTION; CONFORMATIONAL CHANGE; COPPER COORDINATION; COPPER IONS; DIOXYGEN REACTIVITY; DITYROSINE; EMISSION FEATURES; FIBRIL FORMATION; IN-VITRO; PARKINSON'S DISEASE; PRESYNAPTIC; REACTIVE OXYGEN SPECIES; STRUCTURAL REARRANGEMENT; SUB-MICROMOLAR AFFINITY; SYNUCLEIN;

COPPER; LEAKAGE (FLUID); LIGANDS; OXYGEN;

ABSORPTION SPECTROSCOPY;

ALPHA SYNUCLEIN; COPPER; EDETIC ACID; OXYGEN; REACTIVE OXYGEN METABOLITE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; DEGENERATIVE DISEASE; HUMAN; NEUROLOGIC DISEASE; OXIDATION REDUCTION REACTION; PARKINSON DISEASE; PRION DISEASE; PROTEIN CONFORMATION; PROTEIN STRUCTURE; TRANSMISSION ELECTRON MICROSCOPY;

ALPHA-SYNUCLEIN; AMINO ACID SEQUENCE; CIRCULAR DICHROISM; COPPER; HUMANS; MOLECULAR SEQUENCE DATA; OXYGEN; PROTEIN BINDING; SOLUBILITY; SPECTROMETRY, FLUORESCENCE;

EID: 77952390443     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja101756m     Document Type: Article

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