Evaluating cytotoxicity and cellular uptake from the presence of variously processed TiO2 nanostructured morphologies

Chemical Research in Toxicology

Volumn 23, Issue 5, 2010, Pages 871-879

  Chen, Jingyi ^a,c   Zhou, Hongjun ^b,d   Santulli, Alexander C ^b   Wong, Stanislaus S ^a,b  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

^d UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE; NANOMATERIAL; NANOPARTICLE; NANOROD; REACTIVE OXYGEN METABOLITE; TITANIUM DIOXIDE;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; INTERNALIZATION; MORTALITY; ULTRAVIOLET IRRADIATION;

CELL SURVIVAL; FLUORESCEIN-5-ISOTHIOCYANATE; HELA CELLS; HUMANS; METAL NANOPARTICLES; MICROSCOPY, CONFOCAL; PHOTOCHEMICAL PROCESSES; REACTIVE OXYGEN SPECIES; TITANIUM; ULTRAVIOLET RAYS;

ECHINOIDEA;

EID: 77952369096     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900418b     Document Type: Article

References (48)

1. Colvin, V. (2003) The potential environmental impact of engineered nanomaterials Nat. Biotechnol. 21, 1166-1170
2. Kumar, C. S. S. R. (2006) Nanomaterials: Toxicity, Health and Environmental Issues, Wiley-VCH: Weinheim, Germany.
3. Lewinski, N., Colvin, V., and Drezek, R. (2008) Cytotoxicity of nanoparticles Small 4, 26-49
4. Hoffmann, M. R., Martin, S. T., Choi, W., and Bahnemann, D. W. (1995) Environmental applications of semiconductor photocatalysis Chem. Rev. 95, 69-96
5. Burda, C., Chen, X., Narayanan, R., and El-Sayed, M. A. (2005) Chemistry and properties of nanocrystals of different shapes Chem. Rev. 105, 1025-1102
6. Fujishima, A. and Honda, K. (1972) Electrochemical photolysis of water at a semiconductor electrode Nature 238, 37-38
7. Jaeger, C. D. and Bard, A. J. (2002) Spin trapping and electron spin resonance detection of radical intermediates in the photodecomposition of water at titanium dioxide particulate systems J. Phys. Chem. 83, 3146-3152
8. Rao, M. V., Rajeshwar, K., Verneker, V. R. P., and DuBow, J. (2002) Photosynthetic production of hydrogen and hydrogen peroxide on semiconducting oxide grains in aqueous solutions J. Phys. Chem. 84, 1987-1991
9. Harbour, J. R. and Hair, M. L. (2002) Superoxide generation in the photolysis of aqueous cadmium sulfide dispersions. Detection by spin trapping J. Phys. Chem. 81, 1791-1793
10. Lee, M. C., Yoshino, F., Shoji, H., Takahashi, S., Todoki, K., Shimada, S., and Kuse-Barouch, K. (2005) Characterization by electron spin resonance spectroscopy of reactive oxygen species generated by titanium dioxide and hydrogen peroxide J. Dental Res. 84, 178-182
11. Oberdorster, G., Oberdorster, E., and Oberdorster, J. (2005) Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles Environ. Health Perspect. 113, 823-839
12. Bischoff, F. and Bryson, G. (1982) Tissue reaction to and fate of parenterally administered titanium dioxide Res. Commun. Chem. Pathol. Pharmacol. 38, 279-290
13. Jacobs, A., Avalos, J., Brown, P., and Wilkin, J. (1999) Does photosensitivity predict photococarcinogenicity Int. J. Toxicol. 18, 191-198
14. Bernard, B. K., Osheroff, M. R., Hofmann, A., and Mennear, J. H. (1989) Toxicology and carcinogenesis studies of dietary titanium dioxide-coated mica in male and female Fischer 344 rats J. Toxicol. Environ. Health 28, 417-429
15. Chen, J., Dong, X., Zhao, J., and Tang, G. (2009) In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitioneal injection J. Appl. Toxicol. 29, 330-337
16. 2 primary particles in mice Environ. Toxicol. Pharmacol. 24, 239-244
17. Gurr, J.-R., Wang, A. S. S., Chen, C.-H., and Jan, K.-Y. (2005) Ultrafine titanium dioxide particles in the absence of photoactivation can induce oxidative damage to human bronchial epithelial cells Toxicology 213, 66-73
18. 2 rods and dots in rats: toxicity is not dependent upon particle size and surface area Toxicol. Sci. 91, 227-236
19. 2 particles: Differential responses related to surface properties Toxicology 230, 90-104
20. 2 nanorods in rats Exp. Biol. Med. 233, 610-619
21. Hart, G. and Hesterberg, T. (1998) In vitro toxicity of respirable-size particles of diatomaceous earth and crystalline silica compared with asbestos and titanium dioxide J. Occup. Environ. Med. 40, 29-42
22. Stearns, R., Paulauskis, J., and Godleski, J. (2001) Endocytosis of ultrafine particles by A549 cells Am. J. Respir. Cell Mol. Biol. 24, 108-115
23. Westmoreland, C., Walker, T., Matthew, J., and Murdock, J. (1999) Preliminary investigations into the use of a human brochial cell line to screen for respiratory toxins in vitro Toxicol. in Vitro 13, 761-764
24. Linnaimaa, K., Kivipensas, P., and Vainio, H. (1997) Toxicity and cytogenetic studies of ultrafine titanium dioxide in cultured rat liver epithelial cells Toxicol. in Vitro 11, 329-335
25. Afaq, F., Abidi, P., Matin, R., and Rahman, Q. (1998) Cytotoxicity, proosidant effects and antioxidant depletion in rat lung alveolar macrophages exposed to ultra-fine titanium dioxide J. Appl. Toxicol. 18, 307-312
26. Peters, K., Unger, R. E., Kirkpatrick, C. J., Gatti, A. M., and Monari, E. (2004) Effects of nano-scaled particles on endothelial cell function in vitro: studies on viability, proliferation and inflammation J. Mater. Sci. Mater. Med. 15, 321-325
27. Sayes, C. M., Wahi, R., Kurian, P. A., Liu, Y., West, J. L., Ausman, K. D., Warheit, D. B., and Colvin, V. L. (2006) Correlating nanoscale titania structure with toxicity: A cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells Toxicol. Sci. 92, 174-185
28. Jin, C.-Y., Zhu, B.-S., Wang, X.-F., and Lu, Q.-H. (2008) Cytotoxicity of titanium dioxide nanoparticles in mouse fibroblast cells Chem. Res. Toxicol. 21, 1871-1877
29. 2 nanotoxicity J. Nanopart. Res. 11, 1361-1374
30. 2-UHA treatment Toxicol. in Vitro 16, 629-635
31. 2 particles Cancer Res. 52, 2346-2348
32. 2 nanoparticles on Ls-174-t human colon carcinoma cells World J. Gastroenterol 10, 3191-3193
33. Lai, T.-Y. and Lee, W.-C. (2009) Killing of cancer cell line by photoexcitation of folic acid-modified dioxide nanoparticles J. Photochem. Photobiol., A 204, 148-153
34. Tsuji, J. S., Maynard, A. D., Howard, P. C., James, J. T., Lam, C.-W., Warheit, D. B., and Santamaria, A. B. (2006) Research strategies for safety evaluation of nanomaterials, Part IV: risk assessment of nanoparticles Toxicol. Sci. 89, 42-50
35. Mao, Y. and Wong, S. S. (2006) Size- and shape-dependent transformation of nanosized titanate into analogous anatase titania nanostructures J. Am. Chem. Soc. 128, 8217-8226
36. Mao, Y., Kanungo, M., Hemraj-Benny, T., and Wong, S. S. (2005) Synthesis and growth mechanism of titanate and titania one-dimensional nanostructures self-assembled into hollow micrometer-scale spherical aggregates J. Phys. Chem. B 110, 702-710
37. Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays J. Immunol. Methods 65, 55-63
38. Yamamoto, A., Honma, R., Sumita, M., and Hanawa, T. (2004) Cytotoxicity evaluation of ceramic particles of different sizes and shapes J. Biomed. Mater. Res. 68A, 244-256
39. Matta, J. L., Ramos, J. M., Armstrong, R. A., and DAntoni, H. (2005) Environmental UV-A and UV-B threshold doses for apoptosis and necrosis in human fibroblasts Photochem. Photobiol. 81, 563-568
40. 2 nanoparticles damage to cellular membranes and genetic supramolecules Supramol. Sci. 5, 511-513
41. Keston, A. S. and Brandt, R. (1965) The fluorometric analysis of ultramicro quantities of hydrogen peroxide Anal. Biochem. 11, 1-5
42. Brandt, R. and Keston, A. S. (1965) Synthesis of diacetyldichlorofluorescin: A stable reagent for fluorometric analysis Anal. Biochem. 11, 6-9
43. Cathcart, R., Schwiers, E., and Ames, B. N. (1983) Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay Anal. Biochem. 134, 111-116
44. 2 Environ. Sci. Technol. 41, 5149-5153
45. 2 nanorods Adv. Mater. 18, 1033-1037
46. Silverstein, R. M., Webster, F. X., and Kiemle, D. J. (2005) Spectrometric Identification of Organic Compounds, 7 th ed., Wiley, New York.
47. Chithrani, B. D., Ghazani, A. A., and Chan, W. C. W. (2006) Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells Nano Lett. 6, 662-668
48. Shrestha, N. K., Macak, J. M., Schmidt-Stein, F., Hahn, R., Mierke, C. T., Fabry, B., and Schmuki, P. (2009) Magnetically guided titania nanotubes for site-selective photocatalysis and drug release Angew. Chem., Int. Ed. 48, 969-972