Loss of polyubiquitin gene Ubb leads to metabolic and sleep abnormalities in mice

Neuropathology and Applied Neurobiology

Volumn 36, Issue 4, 2010, Pages 285-299

  Ryu, K Y ^a   Fujiki, N ^b   Kazantzis, M ^c   Garza, J C ^d   Bouley, D M ^e   Stahl, A ^c   Lu, X Y ^d   Nishino, S ^f   Kopito, R R ^g  

^a University of Seoul   (South Korea)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f STANFORD UNIVERSITY   (United States)

^g STANFORD UNIVERSITY   (United States)

Author keywords

Glial fibrillary acidic protein; Hypothalamus; Knockout mice; Metabolism; Polyubiquitin gene; Sleep

Indexed keywords

POLYUBIQUITIN; UBIQUITIN B; UNCLASSIFIED DRUG; UBB PROTEIN, MOUSE; UBIQUITIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; CONTROLLED STUDY; ENERGY EXPENDITURE; GENE DISRUPTION; GENE LOSS; GLIOSIS; HYPOTHALAMUS; KNOCKOUT MOUSE; MALE; METABOLIC DISORDER; METABOLIC RATE; MOUSE; NERVE DEGENERATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SLEEP DISORDER; SLEEP STAGE; AGING; ANIMAL; BASAL METABOLIC RATE; BODY TEMPERATURE; CIRCADIAN RHYTHM; DEFICIENCY; ENERGY METABOLISM; GENETICS; GLIA; HOMEOSTASIS; LATERAL HYPOTHALAMUS; METABOLISM; MOTOR ACTIVITY; NERVE CELL; PATHOLOGY; PHYSIOLOGY; SLEEP;

AGING; ANIMALS; ARCUATE NUCLEUS OF HYPOTHALAMUS; BASAL METABOLISM; BODY TEMPERATURE; CIRCADIAN RHYTHM; ENERGY METABOLISM; GLIOSIS; HOMEOSTASIS; HYPOTHALAMIC AREA, LATERAL; MALE; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; NERVE DEGENERATION; NEUROGLIA; NEURONS; PHENOTYPE; SLEEP; SLEEP STAGES; UBIQUITIN;

EID: 77952365844     PISSN: 03051846     EISSN: 13652990     Source Type: Journal    
DOI: 10.1111/j.1365-2990.2009.01057.x     Document Type: Article

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