Bone morphogenetic protein-2 and bone marrow aspirate with allograft as alternatives to autograft in instrumented revision posterolateral lumbar spinal fusion: A minimum two-year follow-up study

Spine

Volumn 35, Issue 11, 2010, Pages 1144-1150

  Taghavi, Cyrus E ^a   Lee, Kwang Bok ^a   Keorochana, Gun ^a   Tzeng, Shiau Tzu ^a   Hyun Yoo, Jeong ^a   Wang, Jeffrey C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bone marrow aspirate; Bone morphogenetic protein; Iliac crest bone graft; Posterolateral fusion; Pseudarthrosis; Revision

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COLLAGEN SPONGE;

ADULT; AGED; ALLOGRAFT; ARTICLE; AUTOGRAFT; BONE GRAFT; BONE MARROW BIOPSY; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; DONOR SITE; DURA MATER; FEMALE; FOLLOW UP; HUMAN; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; OUTCOME ASSESSMENT; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PAIN; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PSEUDARTHROSIS; REPEAT PROCEDURE; RETROSPECTIVE STUDY; SPINE FUSION; VISUAL ANALOG SCALE; X RAY FILM;

ADULT; AGED; BONE MORPHOGENETIC PROTEIN 2; BONE TRANSPLANTATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; LUMBAR VERTEBRAE; LUMBOSACRAL REGION; MALE; MIDDLE AGED; PATIENT SELECTION; REOPERATION; RETROSPECTIVE STUDIES; SPINAL FUSION; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 77952362172     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3181bb5203     Document Type: Article

References (58)

1. DePalma AF, Rothman RH. The nature of pseudoarthrosis. Clin Orthop 1992;284:3-9.
2. Schimandle JH, Boden SD, Hutton WC. Experimental spinal fusion with recombinant human bone morphogenetic protein-2 (rhBMP-2). Spine 1995;20:1326-37.
3. Zdeblick TA. A prospective, randomized study of lumbar fusion: preliminary results. Spine 1993;18:983-91.
4. Younger EM, Chapman MW. Morbidity at the bone graft donor sites. J Orthop Trauma 1989;3:192-5.
5. Arrington ED, Smith WJ, Chambers HG, et al. Complications of iliac crest bone graft harvesting. Clin Orthop 1996;329:300-9.
6. Banwart JC, Asher MA, Hassanein RS. Iliac crest bone graft harvest donor site morbidity: a statistical evaluation. Spine 1995;20:1055-60.
7. Urist MR. Bone: formation by autoinduction. Science 1965;150:893-9.
8. Szpalski M, Gunzburg R. Recombinant human bone morphogenetic protein-2: a novel osteoinductive alternative to autogenous bone graft? Acta Orthop Belg 2005;71:133-48.
9. Govender S, Csimma C, Genant HK, et al. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, randomized study of four hundred and fifty patients. J Bone Joint Surg Am 2002;84:2123-34.
10. Butterman GR. Prospective nonrandomized comparison of an allograft with bone morphogenic protein versus an iliac-crest autograft in anterior cervical discectomy and fusion. Spine J 2008;8:426-35.
11. Glassman SD, Carreon L, Djurasovic M, et al. Posterolateral lumbar spine fusion with INFUSE bone graft. Spine J 2007;7:44-9.
12. Dimar JR, Glassman SD, Burkus KJ, et al. Clinical outcomes and fusion success at 2 years of single-level instrumented posterolateral fusions with recombinant human bone morphogenetic protein-2/compression resistant matrix versus iliac crest bone graft. Spine 2006;31:2534-9.
13. Luhmann SJ, Bridwell KH, Cheng I, et al. Use of bone morphogenetic protein-2 for adult spinal deformity. Spine 2005;30(suppl 17): S110-7.
14. Schwender JD, Holly LT, Rouben DP, et al. Minimally invasive transforaminal lumbar interbody fusion (TLIF): technical feasibility and initial results. J Spinal Disord Tech 2005;18: S1-6.
15. Mummaneni PV, Pan J, Haid RW, et al. Contribution of recombinant human bone morphogenetic protein-2 to the rapid creation of interbody fusion when used in transforaminal lumbar interbody fusion: a preliminary report. J Neurosurg Spine 2004;1:19-23.
16. Haid RW, Branch CL, Alexander JT, et al. Posterior lumbar interbody fusion using recombinant human bone morphogenetic protein type 2 with cylindrical interbody cages. Spine J 2004;4:527-39.
17. Baskin DS, Ryan P, Sonntag V, et al. A prospective, randomized, controlled cervical fusion study using recombinant human bone morphogenetic protein-2 with the Cornerstone-SR allograph ring and the Atlantis anterior cervical plate. Spine 2003;28:1219-25.
18. Boakye M, Mummaneni PV, Garrett M, et al. Anterior cervical discectomy and fusion involving a polyetheretherketone spacer and bone morphogenetic protein. J Neurosurg Spine 2005;2:521-5.
19. Meisel HJ, Schnoring M, Hohaus C, et al. Posterior lumbar interbody fusion using rhBMP-2. Eur Spine J 2008;17:1735-44.
20. Cook SD, Dalton JE, Tan EH, et al. In vivo evaluation of recombinant human osteogenic protein (rhOP-1) implants as a bone graft substitute for spinal fusions. Spine 1994;19:1655-63.
21. Cook SD. Preclinical and clinical evaluation of osteogenic protein-1 (BMP-7) in bony sites. Orthopedics 1999;22:669-71.
22. Paramore CG, Lauryssen C, Rauzzino MJ, et al. The safety of OP-1 for lumbar fusion with decompression: a canine study. Neurosurgery 1999;44:1151-5.
23. Friedlaender GE, Perry CR, Cole JD, et al. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. J Bone Joint Surg Am 2001;83(suppl 1): 151):151-8.
24. Salkeld SL, Patron LP, Barrack RL, et al. The effect of osteogenic protein-1 on the healing of segmental bone defects treated with autograft or allograft bone. J Bone Joint Surg Am 2001;83:803-16.
25. Magin MN, Delling G. Improved lumbar vertebral interbody fusion using rhOP-1: a comparison of autogenous bone graft, bovine hydroxylapatite (Bio-Oss), and BMP-7 (rhOP-1) in sheep. Spine 2001;26:469-78.
26. Grauer JN, Patel TC, Erulkar JS, et al. 2000 Young Investigator Research Award winner. Evaluation of OP-1 as a graft substitute for intertransverse process lumbar fusion. Spine 2001;26:127-33.
27. Johnsson R, Stromqvist B, Aspenberg P. Randomized radiostereometric study comparing osteogenic protein-1 (BMP-7) and autograft bone in human noninstrumented posterolateral lumbar fusion: 2002 Volvo Award in clinical studies. Spine 2002;27:2654-61.
28. Vaccaro AR, Patel T, Fischgrund J, et al. A pilot safety and efficacy study of OP-1 putty (rhBMP-7) as an adjunct to iliac crest autograft in posterolateral lumbar fusions. Eur Spine J 2003;12:495-500.
29. Vaccaro AR, Patel T, Fischgrund J, et al. A pilot study evaluating the safety and efficacy of OP-1 putty (rhBMP-7) as a replacement of iliac crest autograft in posterolateral lumbar arthrodesis for degenerative spondylolisthesis. Spine 2004;29:1885-92.
30. Vaccaro AR, Anderson DG, Patel T, et al. Comparison of OP-1 putty (rh-BMP-7) to iliac crest autograft for posterolateral lumbar arthrodesis. Spine 2005;24:2709-16.
31. Vaccaro AR, Patel T, Fischgrund J, et al. A 2-year follow-up pilot study evaluating the safety and efficacy of OP-1 putty (rhBMP-7) as an adjunct to iliac crest autograft in posterolateral fusions. Eur Spine J 2004;14:623-9.
32. Vaccaro AR, Whang PG, Patel T, et al. The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study. Spine J 2008;8:457-65.
33. Neen D, Noyes D, Shaw M, et al. Healos and bone marrow aspirate used for lumbar spine fusion: a case controlled study comparing Healos with autograft. Spine 2006;31:636-40.
34. Connolly JF. Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis. Clin Orthop Relat Res 1998; (suppl 355): S257-66.
35. Kitchel S. Prospective randomized evaluation of Healos/Bone Marrow Aspirate vs autologous iliac crest bone in instrumented posterolateral lumbar fusion. Proceedings of the NASS 19th Annual Meeting. Spine J 2004;4:3S-119.
36. Chapman MW, Bucholz R, Cornell C. Treatment of acute fractures with a collagen-calcium phosphate graft material: a randomized clinical trial. J Bone Joint Surg Am 1997;79:495-502.
37. Price CT, Connolly JF, Carantzas AC, et al. Comparison of bone grafts for posterior spinal fusion in adolescent idiopathic scoliosis. Spine 2003;28:793-8.
38. Garg NK, Gaur S, Sharma S. Percutaneous autogenous bone marrow grafting in 20 cases of ununited fracture. Acta Orthop Scand 1193;64:671-2.
39. Youssef JA, Wang JC, Lieberman IH, et al. Osteoprogenitor-Enriched Allograft in Lumbar Spinal Fusion: Preliminary Findings from a Two-year Prospective Multi-Center Study. Paper presented at: North American Spine Society 23rd Annual Meeting Pre-Course Section on Spine Biologics and Research: Clinical Usage in Human Papers; October 2008; Toronto, ON.
40. Burwell RG. Studies in the transplantation of bone VII. The fresh composite homograft-autograft of cancellous bone an analysis of factors leading to osteogenesis in marrow transplants and in marrow-containing bone grafts. J Bone Joint Surg Br 1964;46:110-40.
41. Muschler GF, Midura RJ. Connective tissue progenitors: practical concepts for clinical applications. Clin Orthop Relat Res 2002;395:66-80.
42. Kadiyala S, Kraus KH, Attawaia M, et al. Rapid bone regeneration in femoral defects by an autologous osteoprogenitor cell concentrate prepared using an intraoperative selective cell retention technique. In: Transactions of the 49th Annual Meeting of the Orthopaedic Research Society; 2003.
43. Youssef J, Brodke D, Haynesworth S, et al. Selective cell retention technology in spinal fusion. Spine 2003;3:114-5.
44. Hollinger EH, Trawick RH, Boden SD, et al. Morphology of the lumbar inter-transverse process fusion mass in the rabbit model: a comparison between two bone graft materials-rhBMP-2 and autograft. J Spinal Disord 1996;9:125-8.
45. Martin GJ, Boden SD, Morone MA, et al. Posterolateral intertransverse process spinal fusion arthrodesis with rhBMP-2 in a non-human primate: important lessons learned regarding dose, carrier, and safety. J Spinal Disord 1999;12:179-86.
46. Sandhu HS, Kanim LE, Kabo JM, et al. Evaluation of rhBMP-2 with an OPLA carrier in a canine posterolateral (transverse process) spinal fusion model. Spine 1996;20:2669-82.
47. Suh DY, Boden SD, Louis-Ugbo J, et al. Delivery of recombinant human bone morphogenetic protein-2 using a compression resistant matrix in posterolateral spine fusion in the rabbit and in the non-human primate. Spine 2002;27:353-60.
48. Glassman SD, Dimar JR, Carreon LY, et al. Initial fusion rates with recombinant human bone morphogenetic protein-2/compression resistant matrix and a hydroxapatite and tricalcium phosphate/collage carrier in posterolateral spinal fusion. Spine 2005;30:1694-8.
49. Boden SD, Kang J, Sandhu H, et al. Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans. Spine 2002;23:2662-73.
50. Singh K, Smucker JD, Boden SD. Use of recombinant human bone morphogenetic protein-2 as an adjunct in posterolateral lumbar spine fusion. A prospective CT-scan analysis at one and two years. J Spinal Disord Tech 2006;19:416-23.
51. Kraiwattanapong C, Boden SD, Louis-Ugbo J, et al. Comparison of Healos/bone marrow to INFUSE (rhBMP-2/ACS) with a collagen-ceramic sponge bulking agent as graft substitutes for lumbar spine fusion. Spine 2005;30:1001-7.
52. Papakostidis C, Kontakis G, Bhandari M, et al. Efficacy of autologous iliac crest bone graft and bone morphogenetic proteins for posterolateral fusion of lumbar spine: a meta-analysis of the results. Spine 2008;33:680-92.
53. Louis-Ugbo J, Murakami H, Kim HS, et al. Evidence of osteoinduction by Grafton demineralized bone matrix in nonhuman primate spinal fusion. Spine 2004;29:360-6;
54. discussion Z1.
55. Yee AJ, Bae HW, Friess D, et al. Augmentation of rabbit posterolateral spondylodesis using a novel demineralized bone matrix-hyaluronan putty. Spine 2003;28:2435-40.
56. Martin GJ, Boden SD, Titus L, et al. New formulations of demineralized bone matrix as a more effective graft alternative in experimental posterolateral lumbar spine arthrodesis. Spine 1999;24:637-45.
57. Gibson S, McLeod I, Wardlaw D, et al. Allograft versus autograft in instrumented posterolateral lumbar spinal fusion: a randomized control trial. Spine 2002;27:1599-603.
58. Mulconrey DS, Bridwell KH, Flynn J, et al. Bone morphogenetic protein (rhBMP-2) as a substitute for iliac crest bone graft in multilevel adult spinal deformity surgery: minimum two-year evaluation of fusion. Spine 2008;33:2153-9.