Peripherally injected CCK-8S activates CART positive neurons of the paraventricular nucleus in rats

Peptides

Volumn 31, Issue 6, 2010, Pages 1118-1123

  Peter, Lisa ^a   Stengel, Andreas ^b   Noetzel, Steffen ^a   Inhoff, Tobias ^a   Goebel, Miriam ^b   Taché, Yvette ^b   Veh, Rüdiger W ^a   Bannert, Norbert ^c   Grötzinger, Carsten ^a   Wiedenmann, Bertram ^a   Klapp, Burghard F ^a   Mönnikes, Hubert ^d   Kobelt, Peter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ROBERT KOCH INSTITUTE   (Germany)

^d Martin Luther Hospital   (Germany)

Author keywords

c Fos; CART; CCK; Food intake; PVN

Indexed keywords

CCK 8S; CHOLECYSTOKININ; CHOLECYSTOKININ DERIVATIVE; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; DOSE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; SOLITARY TRACT NUCLEUS; SPRAGUE DAWLEY RAT; THALAMUS MIDLINE NUCLEUS;

ANIMALS; ARCUATE NUCLEUS; MALE; NERVE TISSUE PROTEINS; NEURONS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; SINCALIDE;

RATTUS; RODENTIA;

EID: 77952322484     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2010.03.013     Document Type: Article

References (44)

1. Asakawa A., Inui A., Yuzuriha H., Nagata T., Kaga T., Ueno N., et al. Cocaine-amphetamine-regulated transcript influences energy metabolism, anxiety and gastric emptying in mice. Horm Metab Res 33 (2001) 554-558
2. Balkan B., Koylu E., Pogun S., and Kuhar M.J. Effects of adrenalectomy on CART expression in the rat arcuate nucleus. Synapse 50 (2003) 14-19
3. Barrachina M.D., Martinez V., Wang L., Wei J.Y., and Taché Y. Synergistic interaction between leptin and cholecystokinin to reduce short-term food intake in lean mice. Proc Natl Acad Sci USA 94 (1997) 10455-10460
4. Buffa R., Solcia E., and Go V.L. Immunohistochemical identification of the cholecystokinin cell in the intestinal mucosa. Gastroenterology 70 (1976) 528-532
5. Calogero A.E., Nicolosi A.M., Moncada M.L., Coniglione F., Vicari E., Polosa P., et al. Effects of cholecystokinin octapeptide on the hypothalamic-pituitary-adrenal axis function and on vasopressin, prolactin and growth hormone release in humans. Neuroendocrinology 58 (1993) 71-76
6. Chen D.Y., Deutsch J.A., Gonzalez M.F., and Gu Y. The induction and suppression of c-fos expression in the rat brain by cholecystokinin and its antagonist L364,718. Neurosci Lett 149 (1993) 91-94
7. Couceyro P.R., Koylu E.O., and Kuhar M.J. Further studies on the anatomical distribution of CART by in situ hybridization. J Chem Neuroanat 12 (1997) 229-241
8. Day H.E., McKnight A.T., Poat J.A., and Hughes J. Evidence that cholecystokinin induces immediate early gene expression in the brainstem, hypothalamus and amygdala of the rat by a CCKA receptor mechanism. Neuropharmacology 33 (1994) 719-727
9. Eysselein V.E., Eberlein G.A., Hesse W.H., Singer M.V., Goebell H., and Reeve Jr. J.R. Cholecystokinin-58 is the major circulating form of cholecystokinin in canine blood. J Biol Chem 262 (1987) 214-217
10. Gibbs J., Young R.C., and Smith G.P. Cholecystokinin decreases food intake in rats. J Comp Physiol Psychol 84 (1973) 488-495
11. Gibbs J., Young R.C., and Smith G.P. Cholecystokinin elicits satiety in rats with open gastric fistulas. Nature 245 (1973) 323-325
12. Haley G.E., and Flynn F.W. Tachykinin neurokinin 3 receptor signaling in cholecystokinin-elicited release of oxytocin and vasopressin. Am J Physiol Regul Integr Comp Physiol 294 (2008) R1760-R1767
13. Kamilaris T.C., Johnson E.O., Calogero A.E., Kalogeras K.T., Bernardini R., Chrousos G.P., et al. Cholecystokinin-octapeptide stimulates hypothalamic-pituitary-adrenal function in rats: role of corticotropin-releasing hormone. Endocrinology 130 (1992) 1764-1774
14. Kobelt P., Tebbe J.J., Tjandra I., Bae H.G., Rüter J., Klapp B.F., et al. Two immunocytochemical protocols for immunofluorescent detection of c-Fos positive neurons in the rat brain. Brain Res Brain Res Protoc 13 (2004) 45-52
15. Kobelt P., Tebbe J.J., Tjandra I., Stengel A., Bae H.G., Andresen V., et al. CCK inhibits the orexigenic effect of peripheral ghrelin. Am J Physiol Regul Integr Comp Physiol 288 3 (2005) R751-R758
16. Koylu E.O., Couceyro P.R., Lambert P.D., Ling N.C., DeSouza E.B., and Kuhar M.J. Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland. J Neuroendocrinol 9 (1997) 823-833
17. Koylu E.O., Weruaga E., Balkan B., Alonso J.R., Kuhar M.J., and Pogun S. Co-localization of cart peptide immunoreactivity and nitric oxide synthase activity in rat hypothalamus. Brain Res 868 (2000) 352-357
18. Krahn D.D., Gosnell B.A., Levine A.S., and Morley J.E. Behavioral effects of corticotropin-releasing factor: localization and characterization of central effects. Brain Res 443 (1988) 63-69
19. Kristensen P., Judge M.E., Thim L., Ribel U., Christjansen K.N., Wulff B.S., et al. Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 393 (1998) 72-76
20. Larsson L.I., and Rehfeld J.F. Localization and molecular heterogeneity of cholecystokinin in the central and peripheral nervous system. Brain Res 165 (1979) 201-218
21. Maletinska L., Maixnerova J., Matyskova R., Haugvicova R., Pirnik Z., Kiss A., et al. Synergistic effect of CART (cocaine- and amphetamine-regulated transcript) peptide and cholecystokinin on food intake regulation in lean mice. BMC Neurosci 9 (2008) 101
22. Mönnikes H., Lauer G., and Arnold R. Peripheral administration of cholecystokinin activates c-fos expression in the locus coeruleus/subcoeruleus nucleus, dorsal vagal complex and paraventricular nucleus via capsaicin-sensitive vagal afferents and CCK-A receptors in the rat. Brain Res 770 (1997) 277-288
23. Noetzel S., Stengel A., Inhoff T., Goebel M., Wisser A.S., Bannert N., et al. CCK-8S activates c-Fos in a dose-dependent manner in nesfatin-1 immunoreactive neurons in the paraventricular nucleus of the hypothalamus and in the nucleus of the solitary tract of the brainstem. Regul Pept 157 (2009) 84-91
24. Oh-I S., Shimizu H., Satoh T., Okada S., Adachi S., Inoue K., et al. Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature 443 (2006) 709-712
25. Olson B.R., Drutarosky M.D., Chow M.S., Hruby V.J., Stricker E.M., and Verbalis J.G. Oxytocin and an oxytocin agonist administered centrally decrease food intake in rats. Peptides 12 (1991) 113-118
26. Olson B.R., Hoffman G.E., Sved A.F., Stricker E.M., and Verbalis J.G. Cholecystokinin induces c-fos expression in hypothalamic oxytocinergic neurons projecting to the dorsal vagal complex. Brain Res 569 (1992) 238-248
27. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates (1997), Academic Press, San Diego
28. Reeve Jr. J.R., Eysselein V.E., Ho F.J., Chew P., Vigna S.R., Liddle R.A., et al. Natural and synthetic CCK-58. Novel reagents for studying cholecystokinin physiology. Ann NY Acad Sci 713 (1994) 11-21
29. Rehfeld J.F. Neuronal cholecystokinin: one or multiple transmitters?. J Neurochem 44 (1985) 1-10
30. Rehfeld J.F., Hansen H.F., Marley P.D., and Stengaard-Pedersen K. Molecular forms of cholecystokinin in the brain and the relationship to neuronal gastrins. Ann NY Acad Sci 448 (1985) 11-23
31. Ricardo J.A., and Koh E.T. Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat. Brain Res 153 (1978) 1-26
32. Rinaman L., Hoffman G.E., Dohanics J., Le W.W., Stricker E.M., and Verbalis J.G. Cholecystokinin activates catecholaminergic neurons in the caudal medulla that innervate the paraventricular nucleus of the hypothalamus in rats. J Comp Neurol 360 (1995) 246-256
33. Ritter R.C., and Ladenheim E.E. Capsaicin pretreatment attenuates suppression of food intake by cholecystokinin. Am J Physiol 248 (1985) R501-R504
34. Sawchenko P.E., Benoit R., and Brown M.R. Somatostatin 28-immunoreactive inputs to the paraventricular and supraoptic nuclei: principal origin from non-aminergic neurons in the nucleus of the solitary tract. J Chem Neuroanat 1 (1988) 81-94
35. Sawchenko P.E., and Swanson L.W. Central noradrenergic pathways for the integration of hypothalamic neuroendocrine and autonomic responses. Science 214 (1981) 685-687
36. Sawchenko P.E., and Swanson L.W. The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat. Brain Res 257 (1982) 275-325
37. Smith G.P., Jerome C., and Gibbs J. Abdominal vagotomy does not block the satiety effect of bombesin in the rat. Peptides 2 (1981) 409-411
38. Stanley S.A., Small C.J., Murphy K.G., Rayes E., Abbott C.R., Seal L.J., et al. Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats. Brain Res 893 (2001) 186-194
39. Verbalis J.G., Stricker E.M., Robinson A.G., and Hoffman G.E. Cholecystokinin activates c-Fos expression in hypothalamic oxytocin and corticotropin-releasing hormon neurons. J Neuroendocrinol 3 (1991) 205-213
40. Vrang N., Larsen P.J., Kristensen P., and Tang-Christensen M. Central administration of cocaine-amphetamine-regulated transcript activates hypothalamic neuroendocrine neurons in the rat. Endocrinology 141 (2000) 794-801
41. Vrang N., Tang-Christensen M., Larsen P.J., and Kristensen P. Recombinant CART peptide induces c-Fos expression in central areas involved in control of feeding behaviour. Brain Res 818 (1999) 499-509
42. Wang C., Billington C.J., Levine A.S., and Kotz C.M. Effect of CART in the hypothalamic paraventricular nucleus on feeding and uncoupling protein gene expression. Neuroreport 11 (2000) 3251-3255
43. Woods S.C., Seeley R.J., Porte Jr. D., and Schwartz M.W. Signals that regulate food intake and energy homeostasis. Science 280 (1998) 1378-1383
44. Zittel T.T., Glatzle J., Kreis M.E., Starlinger M., Eichner M., Raybould H.E., et al. C-fos protein expression in the nucleus of the solitary tract correlates with cholecystokinin dose injected and food intake in rats. Brain Res 846 (1999) 1-11