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Volumn 47, Issue 9, 2010, Pages 1728-1738

1α,25-Dihydroxyvitamin D3 inhibits transcriptional potential of nuclear factor kappa B in breast cancer cells

Author keywords

Cytokines; Inflammation; NF kappaB; Vitamin D3

Indexed keywords

CALCITRIOL; HISTONE DEACETYLASE 3; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; TRANSCRIPTION FACTOR GAL4; TUMOR NECROSIS FACTOR ALPHA; VITAMIN D; VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR; HISTONE DEACETYLASE; I KAPPA B; NCOR2 PROTEIN, HUMAN; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; VITAMIN;

EID: 77952321071     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.03.004     Document Type: Article
Times cited : (56)

References (63)
  • 1
    • 7944238740 scopus 로고    scopus 로고
    • 1,25-Dihydroxycholecalciferol inhibits apoptosis in C3H10T1/2 murine fibroblast cells through activation of nuclear factor kappaB
    • Adams L.S., Teegarden D. 1,25-Dihydroxycholecalciferol inhibits apoptosis in C3H10T1/2 murine fibroblast cells through activation of nuclear factor kappaB. J. Nutr. 2004, 134:2948-2952.
    • (2004) J. Nutr. , vol.134 , pp. 2948-2952
    • Adams, L.S.1    Teegarden, D.2
  • 2
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: the enemy within
    • Aggarwal B.B. Nuclear factor-kappaB: the enemy within. Cancer Cell 2004, 6:203-208.
    • (2004) Cancer Cell , vol.6 , pp. 203-208
    • Aggarwal, B.B.1
  • 4
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • Auphan N., DiDonato J.A., Rosette C., Helmberg A., Karin M. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 1995, 270:286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 5
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: new discoveries and insights
    • Baldwin A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 1996, 14:649-683.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 6
    • 0035995829 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 stimulates phosphorylation of IkappaBalpha and synergizes with TPA to induce nuclear translocation of NFkappaB during monocytic differentiation of NB4 leukemia cells
    • Berry D.M., Clark C.S., Meckling-Gill K.A. 1alpha,25-dihydroxyvitamin D3 stimulates phosphorylation of IkappaBalpha and synergizes with TPA to induce nuclear translocation of NFkappaB during monocytic differentiation of NB4 leukemia cells. Exp. Cell Res. 2002, 272:176-184.
    • (2002) Exp. Cell Res. , vol.272 , pp. 176-184
    • Berry, D.M.1    Clark, C.S.2    Meckling-Gill, K.A.3
  • 7
    • 0029778179 scopus 로고    scopus 로고
    • Glucocorticoid-mediated repression of NFkappaB activity in endothelial cells does not involve induction of IkappaBalpha synthesis
    • Brostjan C., Anrather J., Csizmadia V., Stroka D., Soares M., Bach F.H., Winkler H. Glucocorticoid-mediated repression of NFkappaB activity in endothelial cells does not involve induction of IkappaBalpha synthesis. J. Biol. Chem. 1996, 271:19612-19616.
    • (1996) J. Biol. Chem. , vol.271 , pp. 19612-19616
    • Brostjan, C.1    Anrather, J.2    Csizmadia, V.3    Stroka, D.4    Soares, M.5    Bach, F.H.6    Winkler, H.7
  • 9
    • 0037011056 scopus 로고    scopus 로고
    • Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB
    • Chen L.F., Mu Y., Greene W.C. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB. EMBO J. 2002, 21:6539-6548.
    • (2002) EMBO J. , vol.21 , pp. 6539-6548
    • Chen, L.F.1    Mu, Y.2    Greene, W.C.3
  • 11
    • 0031459881 scopus 로고    scopus 로고
    • Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation
    • De Bosscher K., Schmitz M.L., Vanden Berghe W., Plaisance S., Fiers W., Haegeman G. Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:13504-13509.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 13504-13509
    • De Bosscher, K.1    Schmitz, M.L.2    Vanden Berghe, W.3    Plaisance, S.4    Fiers, W.5    Haegeman, G.6
  • 12
    • 0027245086 scopus 로고
    • Cytokine-inducible expression in endothelial cells of an I kappa B alpha-like gene is regulated by NF kappa B
    • De Martin R., Vanhove B., Cheng Q., Hofer E., Csizmadia V., Winkler H., Bach F.H. Cytokine-inducible expression in endothelial cells of an I kappa B alpha-like gene is regulated by NF kappa B. EMBO J. 1993, 12:2773-2779.
    • (1993) EMBO J. , vol.12 , pp. 2773-2779
    • De Martin, R.1    Vanhove, B.2    Cheng, Q.3    Hofer, E.4    Csizmadia, V.5    Winkler, H.6    Bach, F.H.7
  • 14
    • 0035200120 scopus 로고    scopus 로고
    • Glucocorticoid receptor activation of the I kappa B alpha promoter within chromatin
    • Deroo B.J., Archer T.K. Glucocorticoid receptor activation of the I kappa B alpha promoter within chromatin. Mol. Biol. Cell 2001, 12:3365-3374.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 3365-3374
    • Deroo, B.J.1    Archer, T.K.2
  • 15
    • 59149098239 scopus 로고    scopus 로고
    • CCAAT enhancer-binding protein alpha is a molecular target of 1,25-dihydroxyvitamin D3 in MCF-7 breast cancer cells
    • Dhawan P., Wieder R., Christakos S. CCAAT enhancer-binding protein alpha is a molecular target of 1,25-dihydroxyvitamin D3 in MCF-7 breast cancer cells. J. Biol. Chem. 2009, 284:3086-3095.
    • (2009) J. Biol. Chem. , vol.284 , pp. 3086-3095
    • Dhawan, P.1    Wieder, R.2    Christakos, S.3
  • 16
    • 3042689432 scopus 로고    scopus 로고
    • The genes of the coactivator TIF2 and the corepressor SMRT are primary 1alpha,25(OH)2D3 targets
    • Dunlop T.W., Väisänen S., Frank C., Carlberg C. The genes of the coactivator TIF2 and the corepressor SMRT are primary 1alpha,25(OH)2D3 targets. J. Steroid Biochem. Mol. Biol. 2004, 89-90:257-260.
    • (2004) J. Steroid Biochem. Mol. Biol. , pp. 257-260
    • Dunlop, T.W.1    Väisänen, S.2    Frank, C.3    Carlberg, C.4
  • 17
    • 18144426719 scopus 로고    scopus 로고
    • NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4
    • Fagerlund R., Kinnunen L., Köhler M., Julkunen I., Melén K. NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4. J. Biol. Chem. 2005, 280:15942-15951.
    • (2005) J. Biol. Chem. , vol.280 , pp. 15942-15951
    • Fagerlund, R.1    Kinnunen, L.2    Köhler, M.3    Julkunen, I.4    Melén, K.5
  • 20
    • 34247156267 scopus 로고    scopus 로고
    • Vitamin D receptor-mediated suppression of RelB in antigen presenting cells: a paradigm for ligand-augmented negative transcriptional regulation
    • Griffin M.D., Dong X., Kumar R. Vitamin D receptor-mediated suppression of RelB in antigen presenting cells: a paradigm for ligand-augmented negative transcriptional regulation. Arch. Biochem. Biophys. 2007, 460:218-226.
    • (2007) Arch. Biochem. Biophys. , vol.460 , pp. 218-226
    • Griffin, M.D.1    Dong, X.2    Kumar, R.3
  • 21
    • 0030608964 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 and a variety of its natural metabolites transcriptionally repress nuclear-factor-kappaB-mediated interleukin-8 gene expression
    • Harant H., Andrew P.J., Reddy G.S., Foglar E., Lindley I.J. 1alpha,25-dihydroxyvitamin D3 and a variety of its natural metabolites transcriptionally repress nuclear-factor-kappaB-mediated interleukin-8 gene expression. Eur. J. Biochem. 1997, 250:63-71.
    • (1997) Eur. J. Biochem. , vol.250 , pp. 63-71
    • Harant, H.1    Andrew, P.J.2    Reddy, G.S.3    Foglar, E.4    Lindley, I.J.5
  • 22
    • 0034744376 scopus 로고    scopus 로고
    • Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent transcription
    • Hay D.C., Kemp G.D., Dargemont C., Hay R.T. Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent transcription. Mol. Cell. Biol. 2001, 21:3482-3490.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3482-3490
    • Hay, D.C.1    Kemp, G.D.2    Dargemont, C.3    Hay, R.T.4
  • 23
    • 0030789420 scopus 로고    scopus 로고
    • I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor
    • Heck S., Bender K., Kullmann M., Göttlicher M., Herrlich P., Cato A.C. I kappaB alpha-independent downregulation of NF-kappaB activity by glucocorticoid receptor. EMBO J. 1996, 16:4698-4707.
    • (1996) EMBO J. , vol.16 , pp. 4698-4707
    • Heck, S.1    Bender, K.2    Kullmann, M.3    Göttlicher, M.4    Herrlich, P.5    Cato, A.C.6
  • 24
    • 30744458869 scopus 로고    scopus 로고
    • IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300
    • Hoberg J.E., Popko A.E., Ramsey C.S., Mayo M.W. IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300. Mol. Cell. Biol. 2006, 26:457-471.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 457-471
    • Hoberg, J.E.1    Popko, A.E.2    Ramsey, C.S.3    Mayo, M.W.4
  • 25
    • 33750448661 scopus 로고    scopus 로고
    • Transcriptional regulation via the NF-kappaB signaling module
    • Hoffmann A., Natoli G., Ghosh G. Transcriptional regulation via the NF-kappaB signaling module. Oncogene 2006, 30:6706-6716.
    • (2006) Oncogene , vol.30 , pp. 6706-6716
    • Hoffmann, A.1    Natoli, G.2    Ghosh, G.3
  • 26
    • 0032823313 scopus 로고    scopus 로고
    • Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways
    • Holtmann H., Winzen R., Holland P., Eickemeier S., Hoffmann E., Wallach D., Malinin N.L., Cooper J.A., Resch K., Kracht M. Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways. Mol. Cell. Biol. 1999, 19:6742-6753.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6742-6753
    • Holtmann, H.1    Winzen, R.2    Holland, P.3    Eickemeier, S.4    Hoffmann, E.5    Wallach, D.6    Malinin, N.L.7    Cooper, J.A.8    Resch, K.9    Kracht, M.10
  • 27
    • 0034463032 scopus 로고    scopus 로고
    • Molecular analysis of the inhibition of monocyte chemoattractant protein-1 gene expression by estrogens and xenoestrogens in MCF-7 cells
    • Inadera H., Sekiya T., Yoshimura T., Matsushima K. Molecular analysis of the inhibition of monocyte chemoattractant protein-1 gene expression by estrogens and xenoestrogens in MCF-7 cells. Endocrinology 2000, 141:50-59.
    • (2000) Endocrinology , vol.141 , pp. 50-59
    • Inadera, H.1    Sekiya, T.2    Yoshimura, T.3    Matsushima, K.4
  • 28
    • 0035045582 scopus 로고    scopus 로고
    • Glucocorticoid receptor-interacting protein-1 and receptor-associated coactivator-3 differentially interact with the vitamin D receptor (VDR) and regulate VDR-retinoid X receptor transcriptional cross-talk
    • Issa L.L., Leong G.M., Barry J.B., Sutherland R.L., Eisman J.A. Glucocorticoid receptor-interacting protein-1 and receptor-associated coactivator-3 differentially interact with the vitamin D receptor (VDR) and regulate VDR-retinoid X receptor transcriptional cross-talk. Endocrinology 2001, 142:1606-1615.
    • (2001) Endocrinology , vol.142 , pp. 1606-1615
    • Issa, L.L.1    Leong, G.M.2    Barry, J.B.3    Sutherland, R.L.4    Eisman, J.A.5
  • 29
    • 35748940962 scopus 로고    scopus 로고
    • Involvement of phosphatidylinositol 3-kinase-mediated up-regulation of I kappa B alpha in anti-inflammatory effect of gemfibrozil in microglia
    • Jana M., Jana A., Liu X., Ghosh S., Pahan K. Involvement of phosphatidylinositol 3-kinase-mediated up-regulation of I kappa B alpha in anti-inflammatory effect of gemfibrozil in microglia. J. Immunol. 2007, 179:4142-4152.
    • (2007) J. Immunol. , vol.179 , pp. 4142-4152
    • Jana, M.1    Jana, A.2    Liu, X.3    Ghosh, S.4    Pahan, K.5
  • 30
    • 0037428385 scopus 로고    scopus 로고
    • The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536
    • Jiang X., Takahashi N., Matsui N., Tetsuka T., Okamoto T. The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536. J. Biol. Chem. 2003, 278:919-926.
    • (2003) J. Biol. Chem. , vol.278 , pp. 919-926
    • Jiang, X.1    Takahashi, N.2    Matsui, N.3    Tetsuka, T.4    Okamoto, T.5
  • 31
    • 0032968493 scopus 로고    scopus 로고
    • The vitamin D receptor binds in a transcriptionally inactive form and without a defined polarity on a retinoic acid response element
    • Jimenez-Lara A.M., Aranda A. The vitamin D receptor binds in a transcriptionally inactive form and without a defined polarity on a retinoic acid response element. FASEB J. 1999, 13:1073-1081.
    • (1999) FASEB J. , vol.13 , pp. 1073-1081
    • Jimenez-Lara, A.M.1    Aranda, A.2
  • 32
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
    • Karin M., Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu. Rev. Immunol. 2000, 18:621-663.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 33
    • 59149096563 scopus 로고    scopus 로고
    • Dysregulation of the C/EBPalpha differentiation pathway in human cancer
    • Koschmieder S., Halmos B., Levantini E., Tenen D.G. Dysregulation of the C/EBPalpha differentiation pathway in human cancer. J. Clin. Oncol. 2009, 27:619-628.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 619-628
    • Koschmieder, S.1    Halmos, B.2    Levantini, E.3    Tenen, D.G.4
  • 34
    • 39749113799 scopus 로고    scopus 로고
    • Vitamin D-resistant diseases
    • Liberman U.A. Vitamin D-resistant diseases. J. Bone Miner. Res. 2007, 22:V105-107.
    • (2007) J. Bone Miner. Res. , vol.22
    • Liberman, U.A.1
  • 35
    • 0036844298 scopus 로고    scopus 로고
    • A novel mutation in helix 12 of the vitamin D receptor impairs coactivator interaction and causes hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia
    • Malloy P.J., Xu R., Peng L., Clark P.A., Feldman D. A novel mutation in helix 12 of the vitamin D receptor impairs coactivator interaction and causes hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia. Mol. Endocrinol. 2002, 16:2538-2546.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 2538-2546
    • Malloy, P.J.1    Xu, R.2    Peng, L.3    Clark, P.A.4    Feldman, D.5
  • 37
    • 0030927167 scopus 로고    scopus 로고
    • Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth
    • Nakshatri H., Bhat-Nakshatri P., Martin D.A., Goulet R.J., Sledge G.W. Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth. Mol. Cell. Biol. 1997, 17:3629-3639.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3629-3639
    • Nakshatri, H.1    Bhat-Nakshatri, P.2    Martin, D.A.3    Goulet, R.J.4    Sledge, G.W.5
  • 39
    • 33748702268 scopus 로고    scopus 로고
    • Nuclear receptors versus inflammation: mechanisms of transrepression
    • Pascual G., Glass C.K. Nuclear receptors versus inflammation: mechanisms of transrepression. Trends Endocrinol. Metab. 2006, 17:321-327.
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 321-327
    • Pascual, G.1    Glass, C.K.2
  • 40
    • 60149087551 scopus 로고    scopus 로고
    • C/EBPalpha or C/EBPalpha oncoproteins regulate the intrinsic and extrinsic apoptotic pathways by direct interaction with NF-kappaB p50 bound to the bcl-2 and FLIP gene promoters
    • Paz-Priel I., Ghosal A.K., Kowalski J., Friedman A.D. C/EBPalpha or C/EBPalpha oncoproteins regulate the intrinsic and extrinsic apoptotic pathways by direct interaction with NF-kappaB p50 bound to the bcl-2 and FLIP gene promoters. Leukemia 2009, 23:365-374.
    • (2009) Leukemia , vol.23 , pp. 365-374
    • Paz-Priel, I.1    Ghosal, A.K.2    Kowalski, J.3    Friedman, A.D.4
  • 42
    • 0030152161 scopus 로고    scopus 로고
    • TNF regulates the in vivo occupancy of both distal and proximal regulatory regions of the MCP-1/JE gene
    • Ping D., Jones P.L., Boss J.M. TNF regulates the in vivo occupancy of both distal and proximal regulatory regions of the MCP-1/JE gene. Immunity 1996, 4:455-469.
    • (1996) Immunity , vol.4 , pp. 455-469
    • Ping, D.1    Jones, P.L.2    Boss, J.M.3
  • 43
    • 2342573009 scopus 로고    scopus 로고
    • The role of corepressors in transcriptional regulation by nuclear hormone receptors
    • Privalsky M.L. The role of corepressors in transcriptional regulation by nuclear hormone receptors. Annu. Rev. Physiol. 2004, 66:315-360.
    • (2004) Annu. Rev. Physiol. , vol.66 , pp. 315-360
    • Privalsky, M.L.1
  • 44
    • 8644271518 scopus 로고    scopus 로고
    • 1alpha,25(OH)(2)D(3) regulates NF-kappaB DNA binding activity in cultured normal human keratinocytes through an increase in IkappaBalpha expression
    • Riis J.L., Johansen C., Gesser B., Møller K., Larsen C.G., Kragballe K., Iversen L. 1alpha,25(OH)(2)D(3) regulates NF-kappaB DNA binding activity in cultured normal human keratinocytes through an increase in IkappaBalpha expression. Arch. Dermatol. Res. 2004, 296:195-202.
    • (2004) Arch. Dermatol. Res. , vol.296 , pp. 195-202
    • Riis, J.L.1    Johansen, C.2    Gesser, B.3    Møller, K.4    Larsen, C.G.5    Kragballe, K.6    Iversen, L.7
  • 45
    • 0032589462 scopus 로고    scopus 로고
    • IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain
    • Sakurai H., Chiba H., Miyoshi H., Sugita T., Toriumi W. IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain. J. Biol. Chem. 1999, 274:30353-30356.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30353-30356
    • Sakurai, H.1    Chiba, H.2    Miyoshi, H.3    Sugita, T.4    Toriumi, W.5
  • 46
    • 44349182071 scopus 로고    scopus 로고
    • Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimers
    • Sánchez-Martínez R., Zambrano A., Castillo A.I., Aranda A. Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimers. Mol. Cell. Biol. 2008, 28:3817-3829.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 3817-3829
    • Sánchez-Martínez, R.1    Zambrano, A.2    Castillo, A.I.3    Aranda, A.4
  • 47
    • 0028879819 scopus 로고
    • Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheinman R.I., Cogswell P.C., Lofquist A.K., Baldwin A.S. Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 1995, 270:283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin, A.S.4
  • 50
    • 54749105918 scopus 로고    scopus 로고
    • Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling
    • Tan X., Wen X., Liu Y. Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kappaB signaling. J. Am. Soc. Nephrol. 2008, 19:1741-1752.
    • (2008) J. Am. Soc. Nephrol. , vol.19 , pp. 1741-1752
    • Tan, X.1    Wen, X.2    Liu, Y.3
  • 51
    • 0030050784 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp
    • Tsai E.Y., Jain J., Pesavento P.A., Rao A., Goldfeld A.E. Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp. Mol. Cell. Biol. 1996, 16:459-467.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 459-467
    • Tsai, E.Y.1    Jain, J.2    Pesavento, P.A.3    Rao, A.4    Goldfeld, A.E.5
  • 52
    • 34247111909 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 induces biphasic NF-kappaB responses during HL-60 leukemia cells differentiation through protein induction and PI3K/Akt-dependent phosphorylation/degradation of IkappaB
    • Tse A.K., Wan C.K., Shen X.L., Zhu G.Y., Cheung H.Y., Yang M., Fong W.F. 1,25-Dihydroxyvitamin D3 induces biphasic NF-kappaB responses during HL-60 leukemia cells differentiation through protein induction and PI3K/Akt-dependent phosphorylation/degradation of IkappaB. Exp. Cell Res. 2007, 313:1722-1734.
    • (2007) Exp. Cell Res. , vol.313 , pp. 1722-1734
    • Tse, A.K.1    Wan, C.K.2    Shen, X.L.3    Zhu, G.Y.4    Cheung, H.Y.5    Yang, M.6    Fong, W.F.7
  • 53
    • 0030707615 scopus 로고    scopus 로고
    • Transcriptional regulation of the human monocyte chemoattractant protein-1 gene. Cooperation of two NF-kappaB sites and NF-kappaB/Rel subunit specificity
    • Ueda A., Ishigatsubo Y., Okubo T., Yoshimura T. Transcriptional regulation of the human monocyte chemoattractant protein-1 gene. Cooperation of two NF-kappaB sites and NF-kappaB/Rel subunit specificity. J. Biol. Chem. 1997, 272:31092-31099.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31092-31099
    • Ueda, A.1    Ishigatsubo, Y.2    Okubo, T.3    Yoshimura, T.4
  • 54
    • 33746669941 scopus 로고    scopus 로고
    • Vitamin D receptor polymorphisms and diseases
    • Valdivielso J.M., Fernandez E. Vitamin D receptor polymorphisms and diseases. Clin. Chim. Acta 2006, 371:1-12.
    • (2006) Clin. Chim. Acta , vol.371 , pp. 1-12
    • Valdivielso, J.M.1    Fernandez, E.2
  • 55
    • 27544499686 scopus 로고    scopus 로고
    • Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts
    • Van Etten E., Mathieu C. Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J. Steroid Biochem. Mol. Biol. 2005, 97:93-101.
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.97 , pp. 93-101
    • Van Etten, E.1    Mathieu, C.2
  • 56
    • 33745213966 scopus 로고    scopus 로고
    • Nuclear factor-kappaB signature of inflammatory breast cancer by cDNA microarray validated by quantitative real-time reverse transcription-PCR, immunohistochemistry, and nuclear factor-kappaB DNA-binding
    • Van Laere S.J., Van der Auwera I., Van den Eynden G.G., Elst H.J., Weyler J., Harris A.L., van Dam P., Van Marck E.A., Vermeulen P.B., Dirix L.Y. Nuclear factor-kappaB signature of inflammatory breast cancer by cDNA microarray validated by quantitative real-time reverse transcription-PCR, immunohistochemistry, and nuclear factor-kappaB DNA-binding. Clin. Cancer Res. 2006, 12:3249-3256.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 3249-3256
    • Van Laere, S.J.1    Van der Auwera, I.2    Van den Eynden, G.G.3    Elst, H.J.4    Weyler, J.5    Harris, A.L.6    van Dam, P.7    Van Marck, E.A.8    Vermeulen, P.B.9    Dirix, L.Y.10
  • 57
    • 0037103133 scopus 로고    scopus 로고
    • Repression of AP-1 function: a mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene
    • Vasanwala F.H., Kusam S., Toney L.M., Dent A.L. Repression of AP-1 function: a mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene. J. Immunol. 2002, 169:1922-1929.
    • (2002) J. Immunol. , vol.169 , pp. 1922-1929
    • Vasanwala, F.H.1    Kusam, S.2    Toney, L.M.3    Dent, A.L.4
  • 60
    • 11844251170 scopus 로고    scopus 로고
    • The NF-kappaB/IkappaB signaling system: a molecular target in breast cancer therapy
    • Wu J.T., Kral J.G. The NF-kappaB/IkappaB signaling system: a molecular target in breast cancer therapy. J. Surg. Res. 2005, 123:158-169.
    • (2005) J. Surg. Res. , vol.123 , pp. 158-169
    • Wu, J.T.1    Kral, J.G.2
  • 61
    • 34447530298 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 targeting of NF-kappaB suppresses high glucose-induced MCP-1 expression in mesangial cells
    • Zhang Z., Yuan W., Sun L., Szeto F.L., Wong K.E., Li X., Kong J., Li Y.C. 1,25-Dihydroxyvitamin D3 targeting of NF-kappaB suppresses high glucose-induced MCP-1 expression in mesangial cells. Kidney Int. 2007, 72:193-201.
    • (2007) Kidney Int. , vol.72 , pp. 193-201
    • Zhang, Z.1    Yuan, W.2    Sun, L.3    Szeto, F.L.4    Wong, K.E.5    Li, X.6    Kong, J.7    Li, Y.C.8
  • 62
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
    • Zhong H., Voll R.E., Ghosh S. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell 1998, 1:661-671.
    • (1998) Mol. Cell , vol.1 , pp. 661-671
    • Zhong, H.1    Voll, R.E.2    Ghosh, S.3
  • 63
    • 0030755397 scopus 로고    scopus 로고
    • Retinoid X receptor (RXR) ligands activate the human 25-hydroxyvitamin D3-24-hydroxylase promoter via RXR heterodimer binding to two vitamin D-responsive elements and elicit additive effects with 1,25-dihydroxyvitamin D3
    • Zou A., Elgort M.G., Allegretto E.A. Retinoid X receptor (RXR) ligands activate the human 25-hydroxyvitamin D3-24-hydroxylase promoter via RXR heterodimer binding to two vitamin D-responsive elements and elicit additive effects with 1,25-dihydroxyvitamin D3. J Biol. Chem. 1997, 272:19027-19034.
    • (1997) J Biol. Chem. , vol.272 , pp. 19027-19034
    • Zou, A.1    Elgort, M.G.2    Allegretto, E.A.3


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