메뉴 건너뛰기




Volumn 30, Issue 7, 2004, Pages 643-650

Evaluating the role of dexrazoxane as a cardioprotectant in cancer patients receiving anthracyclines

Author keywords

Anthracycline; Cancer; Cardioprotectant; Cardiotoxicity; Chemotherapy; Congestive heart failure; Dexrazoxane; Doxorubicin; Epirubicin; Tumour

Indexed keywords

ANTHRACYCLINE DERIVATIVE; CYCLOPHOSPHAMIDE; DAUNORUBICIN; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; IDARUBICIN; PACLITAXEL; PIRARUBICIN; PLACEBO; RAZOXANE; TRASTUZUMAB;

EID: 7544243756     PISSN: 03057372     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ctrv.2004.06.002     Document Type: Article
Times cited : (22)

References (50)
  • 1
    • 0026714331 scopus 로고
    • The anthracyclines: Will we ever find a better doxorubicin
    • Weiss R.B. The anthracyclines: Will we ever find a better doxorubicin Semin. Oncol. 19 1992 670-686
    • (1992) Semin. Oncol. , vol.19 , pp. 670-686
    • Weiss, R.B.1
  • 2
    • 0028877036 scopus 로고
    • Paclitaxel by 3-h infusion in combination with bolus doxorubicin in women with untreated metastatic breast cancer: High antitumor efficacy and cardiac effects in a dose-finding and sequence-finding study
    • Gianni L. Munzone E. Capri G. et al. Paclitaxel by 3-h infusion in combination with bolus doxorubicin in women with untreated metastatic breast cancer: High antitumor efficacy and cardiac effects in a dose-finding and sequence-finding study J. Clin. Oncol. 13 1995 2688-2699
    • (1995) J. Clin. Oncol. , vol.13 , pp. 2688-2699
    • Gianni, L.1    Munzone, E.2    Capri, G.3
  • 3
    • 0029811267 scopus 로고    scopus 로고
    • Doxorubicin and paclitaxel, a highly active combination in the treatment of metastatic breast cancer
    • Dombernowsky P. Gehl J. Boesgaard M. Paaske T. Jensen B.V. Doxorubicin and paclitaxel, a highly active combination in the treatment of metastatic breast cancer Semin. Oncol. 23 1996 23-27
    • (1996) Semin. Oncol. , vol.23 , pp. 23-27
    • Dombernowsky, P.1    Gehl, J.2    Boesgaard, M.3    Paaske, T.4    Jensen, B.V.5
  • 4
    • 0032760998 scopus 로고    scopus 로고
    • Phase II trial of doxorubicin and paclitaxel plus granulocyte colony-stimulating factor in metastatic breast cancer: An Eastern Cooperative Oncology Group Study
    • Sparano J.A. Hu P. Rao R.M. Falkson C.I. Wolff A.C. Wood W.C. Phase II trial of doxorubicin and paclitaxel plus granulocyte colony-stimulating factor in metastatic breast cancer: An Eastern Cooperative Oncology Group Study J. Clin. Oncol. 17 1999 3828-3834
    • (1999) J. Clin. Oncol. , vol.17 , pp. 3828-3834
    • Sparano, J.A.1    Hu, P.2    Rao, R.M.3    Falkson, C.I.4    Wolff, A.C.5    Wood, W.C.6
  • 5
    • 0032872127 scopus 로고    scopus 로고
    • American Society of clinical oncology clinical practice guidelines for the use of chemotherapy and radiotherapy protectants
    • Hensley M.L. Schuchter L.M. Lindley C. et al. American Society of clinical oncology clinical practice guidelines for the use of chemotherapy and radiotherapy protectants J. Clin. Oncol. 17 1999 3333-3355
    • (1999) J. Clin. Oncol. , vol.17 , pp. 3333-3355
    • Hensley, M.L.1    Schuchter, L.M.2    Lindley, C.3
  • 6
    • 85088001597 scopus 로고    scopus 로고
    • Dexrazoxane and the ASCO guidelines for the use of chemotherapy and radiotherapy products: A critique
    • Hellmann K. Dexrazoxane and the ASCO guidelines for the use of chemotherapy and radiotherapy products: A critique J. Clin. Oncol. 18 2000 2004-2006
    • (2000) J. Clin. Oncol. , vol.18 , pp. 2004-2006
    • Hellmann, K.1
  • 8
    • 0018716636 scopus 로고
    • Risk factors for doxorubicin induced congestive heart failure
    • Von Hoff D.D. Layard M.W. Basa P. et al. Risk factors for doxorubicin induced congestive heart failure Ann. Intern. Med. 91 1979 710-717
    • (1979) Ann. Intern. Med. , vol.91 , pp. 710-717
    • Von Hoff, D.D.1    Layard, M.W.2    Basa, P.3
  • 9
    • 0026585672 scopus 로고
    • ICRF-187 permits longer treatment with doxorubicin in women with breast cancer
    • Speyer J.L. Green M.D. Zeleniuch-Jacotte A. et al. ICRF-187 permits longer treatment with doxorubicin in women with breast cancer J. Clin. Oncol. 10 1992 117-127
    • (1992) J. Clin. Oncol. , vol.10 , pp. 117-127
    • Speyer, J.L.1    Green, M.D.2    Zeleniuch-Jacotte, A.3
  • 10
    • 0025850827 scopus 로고
    • Cardiac toxicity 4 to 20 years after completing anthracycline therapy
    • Steinherz L.J. Steinherz P.G. Tan C.T.C. Heller G. Murphy M.L. Cardiac toxicity 4 to 20 years after completing anthracycline therapy JAMA 266 1991 1672-1677
    • (1991) JAMA , vol.266 , pp. 1672-1677
    • Steinherz, L.J.1    Steinherz, P.G.2    Tan, C.T.C.3    Heller, G.4    Murphy, M.L.5
  • 11
    • 0026697794 scopus 로고
    • The cardiotoxicity of chemotherapeutic drugs
    • Allen A. The cardiotoxicity of chemotherapeutic drugs Semin. Oncol. 19 1992 529-542
    • (1992) Semin. Oncol. , vol.19 , pp. 529-542
    • Allen, A.1
  • 12
    • 0028989408 scopus 로고
    • Female sex and drug dose as risk factors for late cardiotoxic effects of doxorubicin therapy for childhood cancer
    • Lipshultz S.E. Lipsitz S.R. Mone S.M. et al. Female sex and drug dose as risk factors for late cardiotoxic effects of doxorubicin therapy for childhood cancer N. Engl. J. Med. 332 1995 1738-1743
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1738-1743
    • Lipshultz, S.E.1    Lipsitz, S.R.2    Mone, S.M.3
  • 13
    • 0020038042 scopus 로고
    • Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion
    • Legha S.S. Benjamin R.S. Mackay B. et al. Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion Ann. Intern. Med. 96 1982 133-139
    • (1982) Ann. Intern. Med. , vol.96 , pp. 133-139
    • Legha, S.S.1    Benjamin, R.S.2    Mackay, B.3
  • 14
    • 0025098002 scopus 로고
    • Reduced cardiotoxicity of doxorubicin by a 6-h infusion regimen
    • Shapira J. Gottfried M. Lisner M. Ravid M. Reduced cardiotoxicity of doxorubicin by a 6-h infusion regimen Cancer 65 1990 870-873
    • (1990) Cancer , vol.65 , pp. 870-873
    • Shapira, J.1    Gottfried, M.2    Lisner, M.3    Ravid, M.4
  • 15
    • 0026042237 scopus 로고
    • A prospective randomized trial of adjuvant chemotherapy with bolus versus continuous infusion of doxorubicin in patients with high grade extremity soft tissue sarcoma and an analysis of prognostic factors
    • Casper E.S. Gaynor J.J. Hadju S.I. et al. A prospective randomized trial of adjuvant chemotherapy with bolus versus continuous infusion of doxorubicin in patients with high grade extremity soft tissue sarcoma and an analysis of prognostic factors Cancer 68 1991 1221-1229
    • (1991) Cancer , vol.68 , pp. 1221-1229
    • Casper, E.S.1    Gaynor, J.J.2    Hadju, S.I.3
  • 16
    • 0019501351 scopus 로고
    • Dose-effect and structure function relationships in doxorubicin cardiomyopathy
    • Bristow M.R. Mason J.W. Billingham M.E. Daniels J.R. Dose-effect and structure function relationships in doxorubicin cardiomyopathy Am. Heart J. 102 1981 709-718
    • (1981) Am. Heart J. , vol.102 , pp. 709-718
    • Bristow, M.R.1    Mason, J.W.2    Billingham, M.E.3    Daniels, J.R.4
  • 17
    • 0007234948 scopus 로고    scopus 로고
    • 48 h continuous doxorubicin infusion is not cardioprotective in children assessed 18 months later: The DFCI 91001 ALL protocol
    • Lipshultz S.E. Sallan S.E. Giantris A.L. Lipsitz S.R. Dalton V. Colan S.D. 48 h continuous doxorubicin infusion is not cardioprotective in children assessed 18 months later: The DFCI 91001 ALL protocol Proc. Am. Soc. Clin. Oncol. 17 1998 2028
    • (1998) Proc. Am. Soc. Clin. Oncol. , vol.17 , pp. 2028
    • Lipshultz, S.E.1    Sallan, S.E.2    Giantris, A.L.3    Lipsitz, S.R.4    Dalton, V.5    Colan, S.D.6
  • 18
    • 0001876212 scopus 로고    scopus 로고
    • A phase II study of Taxotere (T) in combination with doxorubicin (A) as first line chemotherapy (CT) of metastatic breast cancer (MBC)
    • Dieras V. Barthier S. Beuzeboc P. et al. A phase II study of Taxotere (T) in combination with doxorubicin (A) as first line chemotherapy (CT) of metastatic breast cancer (MBC) Breast Cancer Res. Treat 50 1998 226
    • (1998) Breast Cancer Res. Treat. , vol.50 , pp. 226
    • Dieras, V.1    Barthier, S.2    Beuzeboc, P.3
  • 19
    • 0035669577 scopus 로고    scopus 로고
    • Caelyx: Phase II studies in ovarian cancer
    • Johnston S.R. Gore M.E. Caelyx: Phase II studies in ovarian cancer Eur. J. Cancer 37 Suppl. 9 2001 S8-S14
    • (2001) Eur. J. Cancer , vol.37 , Issue.SUPPL. 9
    • Johnston, S.R.1    Gore, M.E.2
  • 20
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon D.J. Leyland-Jones B. Shak S. et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2 N. Engl. J. Med. 344 2001 783-792
    • (2001) N. Engl. J. Med. , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 21
    • 0034474587 scopus 로고    scopus 로고
    • Ongoing and planned adjuvant trials with trastuzumab
    • Perez E.A. Hortobagyi G.N. Ongoing and planned adjuvant trials with trastuzumab Semin. Oncol. 27 2000 26-32
    • (2000) Semin. Oncol. , vol.27 , pp. 26-32
    • Perez, E.A.1    Hortobagyi, G.N.2
  • 22
    • 0034994471 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin: Tolerability and toxicity
    • Goram A.L. Richmond P.L. Pegylated liposomal doxorubicin: Tolerability and toxicity Pharmacotherapy 21 2001 751-763
    • (2001) Pharmacotherapy , vol.21 , pp. 751-763
    • Goram, A.L.1    Richmond, P.L.2
  • 23
    • 0000829134 scopus 로고    scopus 로고
    • Final results of a Phase II study of Taxotere (T), doxorubicin (A) and cyclophosphamide (C) (TAC) as first line chemotherapy (CT) in metastatic breast cancer (MBC) patients
    • Nabholtz J.M. Mackey J.R. Smylie M. et al. Final results of a Phase II study of Taxotere (T), doxorubicin (A) and cyclophosphamide (C) (TAC) as first line chemotherapy (CT) in metastatic breast cancer (MBC) patients Breast Cancer Res. Treat 50 1998 227
    • (1998) Breast Cancer Res. Treat. , vol.50 , pp. 227
    • Nabholtz, J.M.1    Mackey, J.R.2    Smylie, M.3
  • 24
    • 20444394950 scopus 로고    scopus 로고
    • The current and future role of dexrazoxane as a cardioprotectant in anthracycline treatment: Expert panel review
    • [in press; will be published November 2003, issue 12; page numbers to be confirmed]
    • Swain SM Vici P. The current and future role of dexrazoxane as a cardioprotectant in anthracycline treatment: Expert panel review. Cancer Res Clin Oncol 2003 129 [in press; will be published November 2003, issue 12; page numbers to be confirmed]
    • (2003) Cancer Res. Clin. Oncol. , vol.129
    • Swain, S.M.1    Vici, P.2
  • 27
    • 0018403626 scopus 로고
    • Reduction of daunorubicin lethality and myocardial cellular alterations by pretreatment with ICRF-187 in Syrian golden hamsters
    • Herman E.H. Ardalan B. Bier C. Waravdekar V.S. Krop S. Reduction of daunorubicin lethality and myocardial cellular alterations by pretreatment with ICRF-187 in Syrian golden hamsters Cancer Treat Rep. 63 1979 89-92
    • (1979) Cancer Treat. Rep. , vol.63 , pp. 89-92
    • Herman, E.H.1    Ardalan, B.2    Bier, C.3    Waravdekar, V.S.4    Krop, S.5
  • 28
    • 0021893818 scopus 로고
    • Comparison of the effectiveness of (±)-1,2-bis(3,5-dioxopiperazinyl-1-yl) propane (ICRF-187) and N-acetylcysteine in preventing chronic doxorubicin cardiotoxicity in beagles
    • Herman E.H. Ferrans V.J. Myers C.E. Van Vleet J.F. Comparison of the effectiveness of (±)-1,2-bis(3,5-dioxopiperazinyl-1-yl) propane (ICRF-187) and N-acetylcysteine in preventing chronic doxorubicin cardiotoxicity in beagles Cancer Res. 45 1985 276-281
    • (1985) Cancer Res. , vol.45 , pp. 276-281
    • Herman, E.H.1    Ferrans, V.J.2    Myers, C.E.3    Van Vleet, J.F.4
  • 30
    • 0019518585 scopus 로고
    • Reduction of chronic doxorubicin cardiotoxicity in dogs by pretreatment with (±)-1,2-bis(3,5-dioxopiperazinyl-1-yl) propane (ICRF-187)
    • Herman E.H. Ferrans V.J. Reduction of chronic doxorubicin cardiotoxicity in dogs by pretreatment with (±)-1,2-bis(3,5-dioxopiperazinyl-1-yl) propane (ICRF-187) Cancer Res. 41 1981 3436-3440
    • (1981) Cancer Res. , vol.41 , pp. 3436-3440
    • Herman, E.H.1    Ferrans, V.J.2
  • 31
    • 0020568774 scopus 로고
    • Influence of vitamin E and ICRF-187 on chronic doxorubicin cardiotoxicity in miniature swine
    • Herman E.H. Ferrans V.J. Influence of vitamin E and ICRF-187 on chronic doxorubicin cardiotoxicity in miniature swine Lab. Invest. 49 1983 69-77
    • (1983) Lab. Invest. , vol.49 , pp. 69-77
    • Herman, E.H.1    Ferrans, V.J.2
  • 32
    • 0022620588 scopus 로고
    • Pretreatment with ICRF-187 provides long-lasting protection against chronic daunorubicin cardiotoxicity in rabbits
    • Herman E.H. Ferrans V.J. Pretreatment with ICRF-187 provides long-lasting protection against chronic daunorubicin cardiotoxicity in rabbits Cancer Chemother. Pharmacol. 16 1986 102-106
    • (1986) Cancer Chemother. Pharmacol. , vol.16 , pp. 102-106
    • Herman, E.H.1    Ferrans, V.J.2
  • 33
    • 0024519069 scopus 로고
    • Effects of ICRF-187 on the cardiac and renal toxicity of epirubicin in spontaneously hypertensive rats
    • Dardir M. Herman E.H. Ferrans V.J. Effects of ICRF-187 on the cardiac and renal toxicity of epirubicin in spontaneously hypertensive rats Cancer Chemother. Pharmacol. 23 1989 269-275
    • (1989) Cancer Chemother. Pharmacol. , vol.23 , pp. 269-275
    • Dardir, M.1    Herman, E.H.2    Ferrans, V.J.3
  • 34
    • 0024217559 scopus 로고
    • Effect of pretreatment with ICRF-187 on the total cumulative dose of doxorubicin tolerated by beagle dogs
    • Herman E.H. Ferrans V.J. Young R.S.K. Hamlin R.L. Effect of pretreatment with ICRF-187 on the total cumulative dose of doxorubicin tolerated by beagle dogs Cancer Res. 48 1988 6918-6925
    • (1988) Cancer Res. , vol.48 , pp. 6918-6925
    • Herman, E.H.1    Ferrans, V.J.2    Young, R.S.K.3    Hamlin, R.L.4
  • 37
    • 0005982431 scopus 로고
    • Advanced small cell lung cancer treated with CAV (cyclophosphamide + Adriamycin ® + vincristine) chemotherapy and the cardioprotective agent dexrazoxane (ADR529, ICRF187, Zinecard®)
    • Feldmann J.E. Jones S.E. Weisberg S.R. et al. Advanced small cell lung cancer treated with CAV (cyclophosphamide + Adriamycin ® + vincristine) chemotherapy and the cardioprotective agent dexrazoxane (ADR529, ICRF187, Zinecard ®) Proc. Am. Soc. Clin. Oncol. 11 1992 993
    • (1992) Proc. Am. Soc. Clin. Oncol. , vol.11 , pp. 993
    • Feldmann, J.E.1    Jones, S.E.2    Weisberg, S.R.3
  • 38
    • 0031983153 scopus 로고    scopus 로고
    • Randomized prospective clinical trial to evaluate cardio-protection of dexrazoxane in patients with advanced breast cancer and soft tissue sarcomas
    • Lopez M. Vici P. Di Lauro L. et al. Randomized prospective clinical trial to evaluate cardio-protection of dexrazoxane in patients with advanced breast cancer and soft tissue sarcomas J. Clin. Oncol. 16 1998 1-7
    • (1998) J. Clin. Oncol. , vol.16 , pp. 1-7
    • Lopez, M.1    Vici, P.2    Di Lauro, L.3
  • 39
    • 0030904096 scopus 로고    scopus 로고
    • Cardioprotective with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer
    • Swain S.M. Whaley F.S. Gerber M.C. et al. Cardioprotective with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer J. Clin. Oncol. 15 1997 1318-1322
    • (1997) J. Clin. Oncol. , vol.15 , pp. 1318-1322
    • Swain, S.M.1    Whaley, F.S.2    Gerber, M.C.3
  • 40
    • 0023693833 scopus 로고
    • Protective effect of the bispiperazinedione ICRF-187 against doxorubicin-induced cardiac toxicity in women with advanced breast cancer
    • Speyer J.L. Green M.D. Kramer E. et al. Protective effect of the bispiperazinedione ICRF-187 against doxorubicin-induced cardiac toxicity in women with advanced breast cancer New Engl. J. Med. 319 1988 745-752
    • (1988) New Engl. J. Med. , vol.319 , pp. 745-752
    • Speyer, J.L.1    Green, M.D.2    Kramer, E.3
  • 41
    • 0030991044 scopus 로고    scopus 로고
    • Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy
    • Swain S.M. Whaley F.S. Gerber M.C. et al. Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy J. Clin. Oncol. 15 1997 1333-1340
    • (1997) J. Clin. Oncol. , vol.15 , pp. 1333-1340
    • Swain, S.M.1    Whaley, F.S.2    Gerber, M.C.3
  • 42
    • 10544231456 scopus 로고    scopus 로고
    • Multicenter randomized controlled clinical trial to evaluate cardio-protection of dexrazoxane versus no cardio-protection in women receiving epirubicin chemotherapy for advanced breast cancer
    • Venturini M. Michelotti A. Del Mastro L. et al. Multicenter randomized controlled clinical trial to evaluate cardio-protection of dexrazoxane versus no cardio-protection in women receiving epirubicin chemotherapy for advanced breast cancer J. Clin. Oncol. 14 1996 3112-3120
    • (1996) J. Clin. Oncol. , vol.14 , pp. 3112-3120
    • Venturini, M.1    Michelotti, A.2    Del Mastro, L.3
  • 43
    • 9044233260 scopus 로고    scopus 로고
    • Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin
    • Wexler L.H. Andrich M.P. Venzon D. et al. Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin J. Clin. Oncol. 14 1996 362-372
    • (1996) J. Clin. Oncol. , vol.14 , pp. 362-372
    • Wexler, L.H.1    Andrich, M.P.2    Venzon, D.3
  • 44
    • 0000166802 scopus 로고
    • ICRF 187 (Cardioxane) protection against doxorubicin induced cardiomyopathy in paediatric osteosarcoma patients
    • Rubio M.E. Wiegman A. Naeff M.S.J. et al. ICRF 187 (Cardioxane) protection against doxorubicin induced cardiomyopathy in paediatric osteosarcoma patients Proc. Am. Soc. Clin. Oncol. 14 1995 440
    • (1995) Proc. Am. Soc. Clin. Oncol. , vol.14 , pp. 440
    • Rubio, M.E.1    Wiegman, A.2    Naeff, M.S.J.3
  • 45
    • 0027169157 scopus 로고
    • Cardioprotection by ICRF187 against high dose anthracycline toxicity in children with malignant disease
    • Bu'Lock F.A. Gabriel H.M. Oakhill A. Mott M.G. Martin R.P. Cardioprotection by ICRF187 against high dose anthracycline toxicity in children with malignant disease Br. Heart J. 70 1993 185-188
    • (1993) Br. Heart J. , vol.70 , pp. 185-188
    • Bu'Lock, F.A.1    Gabriel, H.M.2    Oakhill, A.3    Mott, M.G.4    Martin, R.P.5
  • 46
    • 0030998937 scopus 로고    scopus 로고
    • Use of ICRF-187 for prevention of anthracycline cardiotoxicity in children: Preliminary results
    • Schiavetti A. Castello M.A. Versacci P. et al. Use of ICRF-187 for prevention of anthracycline cardiotoxicity in children: preliminary results Pediatr. Hematol. Oncol. 14 1997 213-222
    • (1997) Pediatr. Hematol. Oncol. , vol.14 , pp. 213-222
    • Schiavetti, A.1    Castello, M.A.2    Versacci, P.3
  • 47
    • 7544230599 scopus 로고    scopus 로고
    • A phase III randomised comparison of cardioprotection with Cardioxane (dexrazoxane, ICRF187) versus no cardioprotection in women receiving epirubicin chemotherapy for advanced breast cancer
    • Chiron Therapeutics, Amsterdam, The Netherlands. Clinical study report EC-CX-006
    • Chiron Therapeutics, Amsterdam, The Netherlands. A phase III randomised comparison of cardioprotection with Cardioxane (dexrazoxane, ICRF187) versus no cardioprotection in women receiving epirubicin chemotherapy for advanced breast cancer. Clinical study report EC-CX-006, 1999
    • (1999)
  • 48
    • 0022549482 scopus 로고
    • Synergistic activity of doxorubicin and the bisdioxopiperazine (±)-1,2-bis(3,5-dioxopiperazinyl-1-yl) propane (ICRF-187) against murine sarcoma S180 cell line
    • Wadler S. Green M.D. Muggia F.M. Synergistic activity of doxorubicin and the bisdioxopiperazine (±)-1,2-bis(3,5-dioxopiperazinyl-1-yl) propane (ICRF-187) against murine sarcoma S180 cell line Cancer Res. 46 1986 1176-1181
    • (1986) Cancer Res. , vol.46 , pp. 1176-1181
    • Wadler, S.1    Green, M.D.2    Muggia, F.M.3
  • 49
    • 7544242821 scopus 로고    scopus 로고
    • Study of the in vitro cytotoxicity of doxorubicin combined with Cardioxane® to 9 breast cancer cell lines
    • French Marketing Authorization Application File
    • Soudon J. Study of the in vitro cytotoxicity of doxorubicin combined with Cardioxane® to 9 breast cancer cell lines. French Marketing Authorization Application File
    • Soudon, J.1
  • 50
    • 0344741819 scopus 로고
    • Effect of the cardioprotective agent ADR-529 (ICRF187) on the antitumor activity of doxorubicin
    • Verhoef V. Bell V. Filppi J. Effect of the cardioprotective agent ADR-529 (ICRF187) on the antitumor activity of doxorubicin Proc. Am. Assoc. Cancer Res. 29 1988
    • (1988) Proc. Am. Assoc. Cancer Res. , vol.29
    • Verhoef, V.1    Bell, V.2    Filppi, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.