Effect of mutations of the human serpin protein corticosteroid-binding globulin on cortisol-binding, thermal and protease sensitivity

Journal of Steroid Biochemistry and Molecular Biology

Volumn 120, Issue 1, 2010, Pages 30-37

  Braun, Beate C ^a,c   Meyer, Hellmuth A ^a   Reetz, Antje ^a   Fuhrmann, Ulrike ^b   Köhrle, Josef ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b BAYER PHARMA AG   (Germany)

^c LEIBNIZ INSTITUTE FOR ZOO AND WILDLIFE RESEARCH   (Germany)

Author keywords

CBG Lyon; Corticosteroid; Cortisol; Elastase; Heat sensitivity; Hormone binding protein; Reactive center loop; Serpin; Transcortin

Indexed keywords

HYDROCORTISONE; LEUKOCYTE ELASTASE; MUTANT PROTEIN; PROTEINASE; SERINE PROTEINASE INHIBITOR; TRANSCORTIN; RECOMBINANT PROTEIN; SERINE PROTEINASE; SERPINA6 PROTEIN, HUMAN;

ARTICLE; BINDING AFFINITY; CELL STRAIN HEK293; CONTROLLED STUDY; GENE EXPRESSION SYSTEM; GENE MUTATION; HEAT SENSITIVITY; HORMONE BINDING; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; LIGAND BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN STRUCTURE; TEMPERATURE SENSITIVITY; TEMPERATURE STRESS; THERMAL EXPOSURE; WILD TYPE; CELL LINE; CYTOLOGY; GENETICS; HEAT; KIDNEY; METABOLISM; MUTATION; PROTEIN BINDING;

CELL LINE; HOT TEMPERATURE; HUMANS; HYDROCORTISONE; KIDNEY; MUTATION; PROTEIN BINDING; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; TRANSCORTIN;

EID: 77952298641     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2010.03.014     Document Type: Article

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