메뉴 건너뛰기




Volumn 28, Issue 4, 2010, Pages 477-486

Unfolding the long-term pathophysiological processes following an acute inflammatory demyelinating lesion of multiple sclerosis

Author keywords

Brain; FMRI; Human; Inflammation; Magnetic resonance imaging; Magnetic resonance spectroscopy; Multiple sclerosis; Recovery

Indexed keywords

CHOLINE; CORTICOSTEROID; LACTIC ACID; LIPID; N ACETYLASPARTIC ACID;

EID: 77952289454     PISSN: 0730725X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mri.2009.12.011     Document Type: Article
Times cited : (25)

References (40)
  • 1
    • 6944249912 scopus 로고    scopus 로고
    • Biomarkers and surrogate outcomes in neurodegenerative disease: lessons from multiple sclerosis
    • Miller D.H. Biomarkers and surrogate outcomes in neurodegenerative disease: lessons from multiple sclerosis. NeuroRx 2004, 1(2):284-294.
    • (2004) NeuroRx , vol.1 , Issue.2 , pp. 284-294
    • Miller, D.H.1
  • 2
    • 40349097787 scopus 로고    scopus 로고
    • The place of conventional MRI and newly emerging MRI techniques in monitoring different aspects of treatment outcome
    • Zivadinov R., et al. The place of conventional MRI and newly emerging MRI techniques in monitoring different aspects of treatment outcome. J Neurol 2008, 255(Suppl 1):61-74.
    • (2008) J Neurol , vol.255 , Issue.1 SUPPL , pp. 61-74
    • Zivadinov, R.1
  • 3
    • 43949125547 scopus 로고    scopus 로고
    • Functional cortical changes of the sensorimotor network are associated with clinical recovery in multiple sclerosis
    • Mezzapesa D.M., et al. Functional cortical changes of the sensorimotor network are associated with clinical recovery in multiple sclerosis. Hum Brain Mapp 2008, 29(5):562-573.
    • (2008) Hum Brain Mapp , vol.29 , Issue.5 , pp. 562-573
    • Mezzapesa, D.M.1
  • 4
    • 0031743796 scopus 로고    scopus 로고
    • Physiologic MRI of a tumefactive multiple sclerosis lesion
    • Ernst T., et al. Physiologic MRI of a tumefactive multiple sclerosis lesion. Neurology 1998, 51(5):1486-1488.
    • (1998) Neurology , vol.51 , Issue.5 , pp. 1486-1488
    • Ernst, T.1
  • 5
    • 0036953679 scopus 로고    scopus 로고
    • Spectroscopic magnetic resonance imaging of a tumefactive demyelinating lesion
    • Law M., Meltzer D.E., Cha S. Spectroscopic magnetic resonance imaging of a tumefactive demyelinating lesion. Neuroradiology 2002, 44(12):986-989.
    • (2002) Neuroradiology , vol.44 , Issue.12 , pp. 986-989
    • Law, M.1    Meltzer, D.E.2    Cha, S.3
  • 6
    • 0031093663 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy in a pathologically confirmed acute demyelinating lesion
    • Silver N.C., et al. Proton magnetic resonance spectroscopy in a pathologically confirmed acute demyelinating lesion. J Neurol 1997, 244(3):204-207.
    • (1997) J Neurol , vol.244 , Issue.3 , pp. 204-207
    • Silver, N.C.1
  • 7
    • 0346634886 scopus 로고    scopus 로고
    • Tumefactive demyelinating lesions by combined perfusion-weighted and diffusion weighted imaging
    • Tsui E.Y., et al. Tumefactive demyelinating lesions by combined perfusion-weighted and diffusion weighted imaging. Comput Med Imaging Graph 2002, 26(5):343-346.
    • (2002) Comput Med Imaging Graph , vol.26 , Issue.5 , pp. 343-346
    • Tsui, E.Y.1
  • 8
    • 0037122957 scopus 로고    scopus 로고
    • A longitudinal study of abnormalities on MRI and disability from multiple sclerosis
    • Brex P.A., et al. A longitudinal study of abnormalities on MRI and disability from multiple sclerosis. N Engl J Med 2002, 346(3):158-164.
    • (2002) N Engl J Med , vol.346 , Issue.3 , pp. 158-164
    • Brex, P.A.1
  • 9
    • 0028265609 scopus 로고
    • Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions
    • Davie C.A., et al. Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions. Brain 1994, 117(Pt 1):49-58.
    • (1994) Brain , vol.117 , Issue.PART 1 , pp. 49-58
    • Davie, C.A.1
  • 10
    • 0031839220 scopus 로고    scopus 로고
    • Magnetization transfer changes in the normal appearing white matter precede the appearance of enhancing lesions in patients with multiple sclerosis
    • Filippi M., et al. Magnetization transfer changes in the normal appearing white matter precede the appearance of enhancing lesions in patients with multiple sclerosis. Ann Neurol 1998, 43(6):809-814.
    • (1998) Ann Neurol , vol.43 , Issue.6 , pp. 809-814
    • Filippi, M.1
  • 11
    • 0344771115 scopus 로고    scopus 로고
    • Evolution of multiple sclerosis lesions on serial contrast-enhanced T1-weighted and magnetization-transfer MR images
    • Rovira A., et al. Evolution of multiple sclerosis lesions on serial contrast-enhanced T1-weighted and magnetization-transfer MR images. AJNR Am J Neuroradiol 1999, 20(10):1939-1945.
    • (1999) AJNR Am J Neuroradiol , vol.20 , Issue.10 , pp. 1939-1945
    • Rovira, A.1
  • 12
    • 0035083892 scopus 로고    scopus 로고
    • A modified protocol to improve the detection of enhancing brain and spinal cord lesions in multiple sclerosis
    • Silver N.C., et al. A modified protocol to improve the detection of enhancing brain and spinal cord lesions in multiple sclerosis. J Neurol 2001, 248(3):215-224.
    • (2001) J Neurol , vol.248 , Issue.3 , pp. 215-224
    • Silver, N.C.1
  • 13
    • 0034955141 scopus 로고    scopus 로고
    • Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis
    • McDonald W.I., et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001, 50(1):121-127.
    • (2001) Ann Neurol , vol.50 , Issue.1 , pp. 121-127
    • McDonald, W.I.1
  • 14
    • 0024370099 scopus 로고
    • Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites
    • Frahm J., et al. Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites. Magn Reson Med 1989, 11(1):47-63.
    • (1989) Magn Reson Med , vol.11 , Issue.1 , pp. 47-63
    • Frahm, J.1
  • 15
    • 0023636904 scopus 로고
    • Spatial localization in NMR spectroscopy in vivo
    • Bottomley P.A. Spatial localization in NMR spectroscopy in vivo. Ann N Y Acad Sci 1987, 508:333-348.
    • (1987) Ann N Y Acad Sci , vol.508 , pp. 333-348
    • Bottomley, P.A.1
  • 16
    • 0346308381 scopus 로고    scopus 로고
    • Improved method for accurate and efficient quantification of MRS data with use of prior knowledge
    • Vanhamme L., van den Boogaart A., Van Huffel S. Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 1997, 129(1):35-43.
    • (1997) J Magn Reson , vol.129 , Issue.1 , pp. 35-43
    • Vanhamme, L.1    van den Boogaart, A.2    Van Huffel, S.3
  • 17
    • 33846543897 scopus 로고    scopus 로고
    • Onset and underpinnings of white matter atrophy at the very early stage of multiple sclerosis - a two-year longitudinal MRI/MRSI study of corpus callosum
    • Audoin B., et al. Onset and underpinnings of white matter atrophy at the very early stage of multiple sclerosis - a two-year longitudinal MRI/MRSI study of corpus callosum. Mult Scler 2007, 13:41-51.
    • (2007) Mult Scler , vol.13 , pp. 41-51
    • Audoin, B.1
  • 18
    • 0027184842 scopus 로고
    • A multiparametric data analysis showing the potential of localized proton MR spectroscopy in the brain in the metabolic characterization of neurological diseases
    • Confort-Gouny S., et al. A multiparametric data analysis showing the potential of localized proton MR spectroscopy in the brain in the metabolic characterization of neurological diseases. J Neurol Sci 1993, 118:123-133.
    • (1993) J Neurol Sci , vol.118 , pp. 123-133
    • Confort-Gouny, S.1
  • 19
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS)
    • Kurtzke J.F. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983, 33(11):1444-1452.
    • (1983) Neurology , vol.33 , Issue.11 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 20
    • 33749002837 scopus 로고    scopus 로고
    • In vivo proton MR spectroscopy of the human brain
    • Barker P.B., Lin D.D.M. In vivo proton MR spectroscopy of the human brain. Prog Nucl Magn Reson Spectrosc 2006, (49):99-128.
    • (2006) Prog Nucl Magn Reson Spectrosc , Issue.49 , pp. 99-128
    • Barker, P.B.1    Lin, D.D.M.2
  • 21
    • 33751074192 scopus 로고    scopus 로고
    • Biomarkers indicative of blood-brain barrier disruption in multiple sclerosis
    • Waubant E. Biomarkers indicative of blood-brain barrier disruption in multiple sclerosis. Dis Markers 2006, 22(4):235-244.
    • (2006) Dis Markers , vol.22 , Issue.4 , pp. 235-244
    • Waubant, E.1
  • 22
    • 0026000851 scopus 로고
    • Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies
    • Simmons M.L., Frondoza C.G., Coyle J.T. Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies. Neuroscience 1991, 45(1):37-45.
    • (1991) Neuroscience , vol.45 , Issue.1 , pp. 37-45
    • Simmons, M.L.1    Frondoza, C.G.2    Coyle, J.T.3
  • 23
    • 0035871761 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy of the human brain
    • Ross B., Bluml S. Magnetic resonance spectroscopy of the human brain. Anat Rec 2001, 265(2):54-84.
    • (2001) Anat Rec , vol.265 , Issue.2 , pp. 54-84
    • Ross, B.1    Bluml, S.2
  • 24
    • 0035986057 scopus 로고    scopus 로고
    • Serial proton spectroscopy, magnetization transfer ratio and T 2 relaxation in pseudotumoral demyelinating lesions
    • Cucurella M.G., et al. Serial proton spectroscopy, magnetization transfer ratio and T 2 relaxation in pseudotumoral demyelinating lesions. NMR Biomed 2002, 15(4):284-292.
    • (2002) NMR Biomed , vol.15 , Issue.4 , pp. 284-292
    • Cucurella, M.G.1
  • 25
    • 0029609682 scopus 로고
    • Chemical pathology of acute demyelinating lesions and its correlation with disability
    • De Stefano N., et al. Chemical pathology of acute demyelinating lesions and its correlation with disability. Ann Neurol 1995, 38(6):901-909.
    • (1995) Ann Neurol , vol.38 , Issue.6 , pp. 901-909
    • De Stefano, N.1
  • 26
    • 0033981063 scopus 로고    scopus 로고
    • Relating axonal injury to functional recovery in MS
    • Reddy H., et al. Relating axonal injury to functional recovery in MS. Neurology 2000, 54(1):236-239.
    • (2000) Neurology , vol.54 , Issue.1 , pp. 236-239
    • Reddy, H.1
  • 27
    • 0035340273 scopus 로고    scopus 로고
    • Acute and chronic changes of the apparent diffusion coefficient in neurological disorders - biophysical mechanisms and possible underlying histopathology
    • Gass A., Niendorf T., Hirsch J.G. Acute and chronic changes of the apparent diffusion coefficient in neurological disorders - biophysical mechanisms and possible underlying histopathology. J Neurol Sci 2001, 186(Suppl 1):S15-S23.
    • (2001) J Neurol Sci , vol.186 , Issue.1 SUPPL
    • Gass, A.1    Niendorf, T.2    Hirsch, J.G.3
  • 28
    • 0031777202 scopus 로고    scopus 로고
    • Magnetisation transfer imaging: theory and application to multiple sclerosis
    • McGowan J.C., et al. Magnetisation transfer imaging: theory and application to multiple sclerosis. J Neurol Neurosurg Psychiatry 1998, 64(Suppl 1):S66-S69.
    • (1998) J Neurol Neurosurg Psychiatry , vol.64 , Issue.1 SUPPL
    • McGowan, J.C.1
  • 29
    • 24944571009 scopus 로고    scopus 로고
    • Cortical adaptation in patients with MS: a cross-sectional functional MRI study of disease phenotypes
    • Rocca M.A., et al. Cortical adaptation in patients with MS: a cross-sectional functional MRI study of disease phenotypes. Lancet Neurol 2005, 4(10):618-626.
    • (2005) Lancet Neurol , vol.4 , Issue.10 , pp. 618-626
    • Rocca, M.A.1
  • 30
    • 12744260011 scopus 로고    scopus 로고
    • The neuroprotective role of inflammation in nervous system injuries
    • Correale J., Villa A. The neuroprotective role of inflammation in nervous system injuries. J Neurol 2004, 251(11):1304-1316.
    • (2004) J Neurol , vol.251 , Issue.11 , pp. 1304-1316
    • Correale, J.1    Villa, A.2
  • 31
    • 29444431598 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy in the monitoring of multiple sclerosis
    • Narayana P.A. Magnetic resonance spectroscopy in the monitoring of multiple sclerosis. J Neuroimaging 2005, 15(4 Suppl):46S-57S.
    • (2005) J Neuroimaging , vol.15 , Issue.4 SUPPL
    • Narayana, P.A.1
  • 32
    • 4444310685 scopus 로고    scopus 로고
    • Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain
    • Schmierer K., et al. Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain. Ann Neurol 2004, 56(3):407-415.
    • (2004) Ann Neurol , vol.56 , Issue.3 , pp. 407-415
    • Schmierer, K.1
  • 33
    • 48349089936 scopus 로고    scopus 로고
    • CCR5 expression on macrophages/microglia is associated with early remyelination in multiple sclerosis lesions
    • Trebst C., et al. CCR5 expression on macrophages/microglia is associated with early remyelination in multiple sclerosis lesions. Mult Scler 2008, 14(6):728-733.
    • (2008) Mult Scler , vol.14 , Issue.6 , pp. 728-733
    • Trebst, C.1
  • 34
    • 38649112309 scopus 로고    scopus 로고
    • CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure
    • Fitch M.T., Silver J. CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure. Exp Neurol 2008, 209(2):294-301.
    • (2008) Exp Neurol , vol.209 , Issue.2 , pp. 294-301
    • Fitch, M.T.1    Silver, J.2
  • 35
    • 9644310402 scopus 로고    scopus 로고
    • Brain microglia and blood-derived macrophages: molecular profiles and functional roles in multiple sclerosis and animal models of autoimmune demyelinating disease
    • Raivich G., Banati R. Brain microglia and blood-derived macrophages: molecular profiles and functional roles in multiple sclerosis and animal models of autoimmune demyelinating disease. Brain Res Brain Res Rev 2004, 46(3):261-281.
    • (2004) Brain Res Brain Res Rev , vol.46 , Issue.3 , pp. 261-281
    • Raivich, G.1    Banati, R.2
  • 36
    • 37049020205 scopus 로고    scopus 로고
    • The brain as a target for inflammatory processes and neuroprotective strategies
    • Skaper S.D. The brain as a target for inflammatory processes and neuroprotective strategies. Ann N Y Acad Sci 2007, 1122:23-34.
    • (2007) Ann N Y Acad Sci , vol.1122 , pp. 23-34
    • Skaper, S.D.1
  • 37
    • 0347626251 scopus 로고    scopus 로고
    • Correlation between cerebral reorganization and motor recovery after subcortical infarcts
    • Loubinoux I., et al. Correlation between cerebral reorganization and motor recovery after subcortical infarcts. Neuroimage 2003, 20(4):2166-2180.
    • (2003) Neuroimage , vol.20 , Issue.4 , pp. 2166-2180
    • Loubinoux, I.1
  • 38
    • 54449083790 scopus 로고    scopus 로고
    • Constraint-induced movement therapy can improve hemiparetic progressive multiple sclerosis. Preliminary findings
    • Mark V.W., et al. Constraint-induced movement therapy can improve hemiparetic progressive multiple sclerosis. Preliminary findings. Mult Scler 2008, 14(7):992-994.
    • (2008) Mult Scler , vol.14 , Issue.7 , pp. 992-994
    • Mark, V.W.1
  • 39
    • 42349089231 scopus 로고    scopus 로고
    • Neural stem cells, inflammation and NF-kappaB: basic principle of maintenance and repair or origin of brain tumours?
    • Widera D., et al. Neural stem cells, inflammation and NF-kappaB: basic principle of maintenance and repair or origin of brain tumours?. J Cell Mol Med 2008, 12(2):459-470.
    • (2008) J Cell Mol Med , vol.12 , Issue.2 , pp. 459-470
    • Widera, D.1
  • 40
    • 33846596215 scopus 로고    scopus 로고
    • Imaging inflammation in acute brain ischemia
    • Jander S., Schroeter M., Saleh A. Imaging inflammation in acute brain ischemia. Stroke 2007, 38(2 Suppl):642-645.
    • (2007) Stroke , vol.38 , Issue.2 SUPPL , pp. 642-645
    • Jander, S.1    Schroeter, M.2    Saleh, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.