Dilated cardiomyopathy alters the expression patterns of car and other adenoviral receptors in human heart

Histochemistry and Cell Biology

Volumn 133, Issue 3, 2010, Pages 349-357

  Toivonen, Raine ^a   Mäyränpää, Mikko I ^b   Kovanen, Petri T ^b   Savontaus, Mikko ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b WIHURI RESEARCH INSTITUTE   (Finland)

Author keywords

Adenovirus; Cardiomyopathy; Gene therapy; Targeting

Indexed keywords

ACETYLSALICYLIC ACID; ADENOVIRUS RECEPTOR; ADENOVIRUS VECTOR; B7 ANTIGEN; BETA ACTIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CD86 ANTIGEN; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEMBRANE COFACTOR PROTEIN; UNCLASSIFIED DRUG; VIRUS RECEPTOR; WARFARIN;

ADOLESCENT; ADULT; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; CORONARY BLOOD VESSEL; ENDOTHELIUM CELL; EXPLANT; FEMALE; GENE THERAPY; GENE TRANSFER; HEART FAILURE; HEART TRANSPLANTATION; HISTOCHEMISTRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; ORGAN DONOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROTYPE; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

ADOLESCENT; ADULT; ANTIGENS, CD46; BLOTTING, WESTERN; CARDIOMYOPATHY, DILATED; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MYOCARDIUM; RECEPTORS, VIRUS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ADENOVIRIDAE;

EID: 77952288803     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-009-0666-1     Document Type: Article

References (40)

1. Akdere F, Bock O, Lehmann U et al (2005) Quantitative mRNA expression analysis of co-stimulatory molecules in sequential biopsies from heart allografts. Transpl Int 18:1197-1202. doi: 10.1111/j.1432-2277.2005.00199.x (Pubitemid 41726764)
2. Amin KM (2003) Ad5 and Ad3 chimeric fiber travels into the cell without the CAR. Cancer Biol Ther 2:516-517
3. Asaoka K, Tada M, Sawamura Y, Ikeda J, Abe H (2000) Dependence of efficient adenoviral gene delivery in malignant glioma cells on the expression levels of the Coxsackievirus and adenovirus receptor. J Neurosurg 92:1002-1008 (Pubitemid 30346520)
4. Brooks PC, Clark RA, Cheresh DA (1994) Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 264:569-571
5. Cheresh DA (1987) Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor. Proc Natl Acad Sci USA 84:6471-6475 (Pubitemid 18002812)
6. Cirielli C, Serino F, Straino S et al (2004) Adenovirus vectors targeting alphaV integrin or heparan sulfate receptors display different distribution of transgene activity after intramuscular injection. J Gene Med 6:309-316. doi:10.1002/jgm.521 (Pubitemid 40228048)
7. Dorig RE, Marcil A, Chopra A, Richardson CD (1993) The human CD46 molecule is a receptor for measles virus (Edmonston strain). Cell 75:295-305 (Pubitemid 23320293)
8. Douglas JT, Kim M, Sumerel LA, Carey DE, Curiel DT (2001) Efficient oncolysis by a replicating adenovirus (ad) in vivo is critically dependent on tumor expression of primary ad receptors. Cancer Res 61:813-817 (Pubitemid 32174383)
9. Einfeld DA, Schroeder R, Roelvink PW et al (2001) Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions. J Virol 75:11284-11291. doi: 10.1128/JVI.75.23.11284-11291.2001 (Pubitemid 33063218)
10. Fechner H, Noutsias M, Tschoepe C et al (2003) Induction of coxsackievirus-adenovirus-receptor expression during myocardial tissue formation and remodeling: identification of a cellto-cell contact-dependent regulatory mechanism. Circulation 107:876-882 (Pubitemid 36241047)
11. Gaggar A, Shayakhmetov DM, Lieber A (2003) CD46 is a cellular receptor for group B adenoviruses. Nat Med 9:1408-1412. doi: 10.1038/nm952 (Pubitemid 37466191)
12. Giaginis CT, Zarros AC, Papaefthymiou MA, Papadopouli AE, Sfiniadakis IK, Theocharis SE (2008) Coxsackievirus and adenovirus receptor expression in human endometrial adenocarcinoma: possible clinical implications. World J Surg Oncol 6:59. doi:10.1186/1477-7819-6-59 (Pubitemid 351935855)
13. Havenga MJ, Lemckert AA, Ophorst OJ et al (2002) Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease. J Virol 76:4612-4620
14. Hemmi S, Geertsen R, Mezzacasa A, Peter I, Dummer R (1998) The presence of human coxsackievirus and adenovirus receptor is associated with efficient adenovirus-mediated transgene expression in human melanoma cell cultures. Hum Gene Ther 9:2363-2373 (Pubitemid 28523985)
15. Janat MF, Argraves WS, Liau G (1992) Regulation of vascular smooth muscle cell integrin expression by transforming growth factor beta1 and by platelet-derived growth factor-BB. J Cell Physiol 151:588-595. doi:10.1002/jcp. 1041510319
16. Kalinowski L, Dobrucki LW, Meoli DF et al (2008) Targeted imaging of hypoxia-induced integrin activation in myocardium early after infarction. J Appl Physiol 104:1504-1512. doi:10.1152/japplphysiol.00861.2007
17. Kanerva A, Mikheeva GV, Krasnykh V et al (2002) Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells. Clin Cancer Res 8:275-280 (Pubitemid 34101488)
18. Kasono K, Blackwell JL, Douglas JT et al (1999) Selective gene delivery to head and neck cancer cells via an integrin targeted adenoviral vector. Clin Cancer Res 5:2571-2579 (Pubitemid 29437344)
19. Kuhl U, Pauschinger M, Seeberg B et al (2005) Viral persistence in the myocardium is associated with progressive cardiac dysfunction. Circulation 112:1965-1970. doi:10.1161/CIRCULATIONAHA. 105.548156 (Pubitemid 41377415)
20. Larochelle N, Deol JR, Srivastava V et al (2008) Downregulation of CD46 during muscle differentiation: implications for gene transfer to human skeletal muscle using group B adenoviruses. Hum Gene Ther 19:133-142. doi:10.1089/hum.2007.040 (Pubitemid 351271507)
21. Li D, Duan L, Freimuth P, O'Malley BW Jr (1999) Variability of adenovirus receptor density influences gene transfer efficiency and therapeutic response in head and neck cancer. Clin Cancer Res 5:4175-4181 (Pubitemid 30013802)
22. Matsumoto K, Shariat SF, Ayala GE, Rauen KA, Lerner SP (2005) Loss of coxsackie and adenovirus receptor expression is associated with features of aggressive bladder cancer. Urology 66:441-446. doi:10.1016/j.urology.2005.02.033 (Pubitemid 41138121)
23. Nettelbeck DM, Miller DW, Jerome V et al (2001) Targeting of adenovirus to endothelial cells by a bispecific single-chain diabody directed against the adenovirus fiber knob domain and human endoglin (CD105). Mol Ther 3:882-891. doi:10.1006/mthe.2001.0342 (Pubitemid 32611298)
24. Noutsias M, Seeberg B, Schultheiss HP, Kuhl U (1999) Expression of cell adhesion molecules in dilated cardiomyopathy: evidence for endothelial activation in inflammatory cardiomyopathy. Circulation 99:2124-2131 (Pubitemid 29196796)
25. Noutsias M, Fechner H, de Jonge H et al (2001) Human coxsackieadenovirus receptor is colocalized with integrins alpha (v) beta (3) and alpha (v) beta (5) on the cardiomyocyte sarcolemma and upregulated in dilated cardiomyopathy: implications for cardiotropic viral infections. Circulation 104:275-280 (Pubitemid 32666947)
26. Rauen KA, Sudilovsky D, Le JL et al (2002) Expression of the coxsackie adenovirus receptor in normal prostate and in primary and metastatic prostate carcinoma: potential relevance to gene therapy. Cancer Res 62:3812-3818 (Pubitemid 34728866)
27. Rissanen TT, Yla-Herttuala S (2007) Current status of cardiovascular gene therapy. Mol Ther 15:1233-1247. doi:10.1038/sj.mt. 6300175 (Pubitemid 46965318)
28. Santoro F, Kennedy PE, Locatelli G, Malnati MS, Berger EA, Lusso P (1999) CD46 is a cellular receptor for human herpesvirus 6. Cell 99:817-827 (Pubitemid 30017651)
29. Sasse A, Wallich M, Ding Z, Goedecke A, Schrader J (2003) Coxsackie-and-adenovirus receptor mRNA expression in human heart failure. J Gene Med 5:876-882. doi:10.1002/jgm.411 (Pubitemid 40310412)
30. Segerman A, Mei YF, Wadell G (2000) Adenovirus types 11p and 35p show high binding efficiencies for committed hematopoietic cell lines and are infective to these cell lines. J Virol 74:1457-1467 (Pubitemid 30044096)
31. Seya T, Hirano A, Matsumoto M, Nomura M, Ueda S (1999) Human membrane cofactor protein (MCP, CD46): multiple isoforms and functions. Int J Biochem Cell Biol 31:1255-1260 (Pubitemid 29486707)
32. Shayakhmetov DM, Li ZY, Ni S, Lieber A (2002) Targeting of adenovirus vectors to tumor cells does not enable efficient transduction of breast cancer metastases. Cancer Res 62:1063-1068 (Pubitemid 34160288)
33. Shinozaki K, Suominen E, Carrick F et al (2006) Efficient infection of tumor endothelial cells by a capsid-modified adenovirus. Gene Ther 13:52-59. doi:10.1038/sj.gt.3302598 (Pubitemid 41823851)
34. Short JJ, Pereboev AV, Kawakami Y, Vasu C, Holterman MJ, Curiel DT (2004) Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors. Virology 322:349-359. doi:10.1016/j.virol.2004.02.016 (Pubitemid 38521149)
35. Sova P, Ren XW, Ni S et al (2004) A tumor-targeted and conditionally replicating oncolytic adenovirus vector expressing TRAIL for treatment of liver metastases. Mol Ther 9:496-509. doi:10.1016/j.ymthe.2003.12.008 (Pubitemid 38578800)
36. Suominen E, Toivonen R, Grenman R, Savontaus M (2006) Head and neck cancer cells are efficiently infected by Ad5/35 hybrid virus. J Gene Med 8 (10):1223-1231. doi:10.1002/jgm.957 (Pubitemid 44660521)
37. van der Merwe PA, Bodian DL, Daenke S, Linsley P, Davis SJ (1997) CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics. J Exp Med 185:393-403 (Pubitemid 27078358)
38. Wickham TJ, Mathias P, Cheresh DA, Nemerow GR (1993) Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 73:309-319
39. Wickham TJ, Segal DM, Roelvink PW et al (1996) Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies. J Virol 70:6831-6838
40. Zeimet AG, Muller-Holzner E, Schuler A et al (2002) Determination of molecules regulating gene delivery using adenoviral vectors in ovarian carcinomas. Gene Ther 9:1093-1100. doi:10.1038/sj.gt.3301775