First nationwide study on driving under the influence of drugs in Switzerland

Forensic Science International

Volumn 198, Issue 1-3, 2010, Pages 11-16

  Senna, Maria Cristina ^a   Augsburger, Marc ^a   Aebi, Beat ^b,h   Briellmann, Thomas A ^c   Donzé, Nicolas ^d   Dubugnon, Jean Luc ^e   Iten, Peter X ^f   Staub, Christian ^a   Sturm, Walter ^g   Sutter, Karl ^g  

^a UNIVERSITY CENTER OF LEGAL MEDICINE   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d Central Institute of the Valais Hospitals   (Switzerland)

^e Institut de Chimie Clinique   (Switzerland)

^f UNIVERSITY OF ZURICH   (Switzerland)

^g CANTONAL HOSPITAL ST GALLEN   (Switzerland)

^h Spiez Laboratory   (Switzerland)

Author keywords

Alcohol; Driving under the influence of drugs (DUID); Drugs; Swiss Legislation; Zero tolerance approach

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALPRAZOLAM; AMITRIPTYLINE; AMPHETAMINE; BENZODIAZEPINE DERIVATIVE; BENZOYLECGONINE; BROMAZEPAM; CANNABINOID; CITALOPRAM; COCAINE; DEALKYLFLURAZEPAM; DIAZEPAM; DIPHENHYDRAMINE; DRONABINOL; ECGONINE METHYL ESTER; FLUOXETINE; LORAZEPAM; METHADONE; METHAMPHETAMINE; METHAQUALONE; MIDAZOLAM; MORPHINE; N ETHYL 3,4 METHYLENEDIOXYAMPHETAMINE; NORDAZEPAM; OXAZEPAM; VENLAFAXINE;

ADULT; AGE DISTRIBUTION; AGED; ALCOHOL BLOOD LEVEL; ARTICLE; BLOOD ANALYSIS; DRIVING ABILITY; DRUG ABUSE; DRUNKEN DRIVING; FALSE POSITIVE RESULT; FEMALE; FORENSIC TOXICOLOGY; HUMAN; MALE; PREVALENCE; PRIORITY JOURNAL; SEX RATIO; SWITZERLAND; TRAFFIC ACCIDENT; TRAFFIC SAFETY; URINALYSIS;

EID: 77952287705     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2010.02.014     Document Type: Article

References (41)

1. Holmgren A., Holmgren P., Kugelberg F.C., Jones A.W., Ahlner J. High re-arrest rates among drug-impaired drivers despite zero-tolerance legislation. Accid. Anal. Prev. 2008, 40:534-540.
2. Walsh J.M., De Gier J.J., Christopherson A.S., Verstraete A.G. Drugs and driving. Traffic Inj. Prev. 2004, 5:241-253.
3. Smink B.E., Ruiter B., Lusthof K.J., Zweipfenning P.G. Driving under the influence of alcohol and/or drugs in the Netherlands 1995-1998 in view of the German and Belgian legislation. Forensic Sci. Int. 2001, 120:195-203.
4. Jones A.W. Driving under the influence of drugs in Sweden with zero concentration limits in blood for controlled substances. Traffic Inj. Prev. 2005, 6:317-322.
5. Cheng J.Y., Chan D.T., Mok V.K. An epidemiological study on alcohol/drugs related fatal traffic crash cases of deceased drivers in Hong Kong between 1996 and 2000. Forensic Sci. Int. 2005, 153:196-201.
6. Christophersen A.S., Ceder G., Kristinsson J., Lillsunde P., Steentoft A. Drugged driving in the Nordic countries-a comparative study between five countries. Forensic Sci. Int. 1999, 106:173-190.
7. Christophersen A.S., Morland J. Drugged driving, a review based on the experience in Norway. Drug Alcohol Depend. 1997, 47:125-135.
8. Gonzalez-Wilhelm L. Prevalence of alcohol and illicit drugs in blood specimens from drivers involved in traffic law offenses. Systematic review of cross-sectional studies. Traffic Inj. Prev. 2007, 8:189-198.
9. Holmgren A., Holmgren P., Kugelberg F.C., Jones A.W., Ahlner J. Predominance of illicit drugs and poly-drug use among drug-impaired drivers in Sweden. Traffic Inj. Prev. 2007, 8:361-367.
10. Holmgren P., Holmgren A., Ahlner J. Alcohol and drugs in drivers fatally injured in traffic accidents in Sweden during the years 2000-2002. Forensic Sci. Int. 2005, 151:11-17.
11. Jones A.W., Holmgren A., Holmgren P. High concentrations of diazepam and nordiazepam in blood of impaired drivers: association with age, gender and spectrum of other drugs present. Forensic Sci. Int. 2004, 146:1-7.
12. Jones A.W., Holmgren A., Kugelberg F.C. Concentrations of scheduled prescription drugs in blood of impaired drivers: considerations for interpreting the results. Ther. Drug Monit. 2007, 29:248-260.
13. Jones A.W., Holmgren A., Kugelberg F.C. Driving under the influence of opiates: concentration relationships between morphine, codeine, 6-acetyl morphine, and ethyl morphine in blood. J. Anal. Toxicol. 2008, 32:265-272.
14. Jones A.W., Kugelberg F.C., Holmgren A., Ahlner J. Five-year update on the occurrence of alcohol and other drugs in blood samples from drivers killed in road-traffic crashes in Sweden. Forensic Sci. Int. 2009, 186:56-62.
15. Lillsunde P., Korte T., Michelson L., Portman M., Pikkarainen J., Seppala T. Drugs usage of drivers suspected of driving under the influence of alcohol and/or drugs. A study of one week's samples in 1979 and 1993 in Finland. Forensic Sci. Int. 1996, 77:119-129.
16. Mura P., Chatelain C., Dumestre V., Gaulier J.M., Ghysel M.H., Lacroix C., Kergueris M.F., Lhermitte M., Moulsma M., Pepin G., Vincent F., Kintz P. Use of drugs of abuse in less than 30-year-old drivers killed in a road crash in France: a spectacular increase for cannabis, cocaine and amphetamines. Forensic Sci. Int. 2006, 160:168-172.
17. Mura P., Kintz P., Ludes B., Gaulier J.M., Marquet P., Martin-Dupont S., Vincent F., Kaddour A., Goulle J.P., Nouveau J., Moulsma M., Tilhet-Coartet S., Pourrat O. Comparison of the prevalence of alcohol, cannabis and other drugs between 900 injured drivers and 900 control subjects: results of a French collaborative study. Forensic Sci. Int. 2003, 133:79-85.
18. Ojaniemi K.K., Lintonen T.P., Impinen A.O., Lillsunde P.M., Ostamo A.I. Trends in driving under the influence of drugs: a register-based study of DUID suspects during 1977-2007. Accid. Anal. Prev. 2009, 41:191-196.
19. Seymour A., Oliver J.S. Role of drugs and alcohol in impaired drivers and fatally injured drivers in the Strathclyde police region of Scotland, 1995-1998. Forensic Sci. Int. 1999, 103:89-100.
20. Drummer O.H., Gerostamoulos J., Batziris H., Chu M., Caplehorn J., Robertson M.D., Swann P. The involvement of drugs in drivers of motor vehicles killed in Australian road traffic crashes. Accid. Anal. Prev. 2004, 36:239-248.
21. Drummer O.H., Gerostamoulos J., Batziris H., Chu M., Caplehorn J.R., Robertson M.D., Swann P. The incidence of drugs in drivers killed in Australian road traffic crashes. Forensic Sci. Int. 2003, 134:154-162.
22. Kelly E., Darke S., Ross J. A review of drug use and driving: epidemiology, impairment, risk factors and risk perceptions. Drug Alcohol Rev. 2004, 23:319-344.
23. Papadodima S.A., Athanaselis S.A., Stefanidou M.E., Dona A.A., Papoutsis I., Maravelias C.P., Spiliopoulou C.A. Driving under the influence in Greece: a 7-year survey (1998-2004). Forensic Sci. Int. 2008, 174:157-160.
24. Staub C., Lacalle H., Fryc O. Presence of psychotropic drugs in the blood of drivers responsible for car accidents, and who consumed alcohol at the same time. Soz. Praventivmed. 1994, 39:143-149.
25. A. Friedrich-Koch, P.X. Iten, Die Verminderung der Fahrfähigkeit durch Drogen und Medikamente. Eine retrospective Studie anhand von 243 Strassenverkehrsfällen aus den Jahren 1989-1991, Institut für Rechtsmedizin der Universität Zürich, Zürich, 1994.
26. Augsburger M., Rivier L. Drugs and alcohol among suspected impaired drivers in Canton de Vaud (Switzerland). Forensic Sci. Int. 1997, 85:95-104.
27. Augsburger M., Donzé N., Menetrey A., Brossard C., Sporkert F., Giroud C., Mangin P. Concentration of drugs in blood of suspected impaired drivers. Forensic Sci. Int. 2005, 153:11-15.
28. Sutter K. Determination of ethanol in blood: analytical aspects, quality control, and theoretical calculations for forensic applications. Chimia 2002, 56:59-62.
29. Drummer O.H., Gerostamoulos D., Chu M., Swann P., Boorman M., Cairns I. Drugs in oral fluid in randomly selected drivers. Forensic Sci. Int. 2007, 170:105-110.
30. Smink B.E., Movig K.L., Lusthof K.J., De Gier J.J., Uges D.R., Egberts A.C. The relation between the use of psychoactive substances and the severity of the injury in a group of crash-involved drivers admitted to a regional trauma center. Traffic Inj. Prev. 2008, 9:105-108.
31. Huestis M.A., Henningfield J.E., Cone E.J. Blood cannabinoids. I. Absorption of THC and formation of 11-OH-THC and THCCOOH during and after smoking marijuana. J. Anal. Toxicol. 1992, 16:276-282.
32. Mura P., Kintz P., Dumestre V., Raul S., Hauet T. THC can be detected in brain while absent in blood. J. Anal. Toxicol. 2005, 29:842-843.
33. Jones A.W., Holmgren A., Kugelberg F.C. Driving under the influence of cannabis: a 10-year study of age and gender differences in the concentrations of tetrahydrocannabinol in blood. Addiction 2008, 103:452-461.
34. Busuttil A., Obafunwa J.O., Bulgin S. Passive inhalation of cannabis smoke: a novel defence strategy?. J. Clin. Forensic Med. 1996, 3:99-104.
35. Cone E.J., Johnson R.E., Darwin W.D., Yousefnejad D., Mell L.D., Paul B.D., Mitchell J. Passive inhalation of marijuana smoke: urinalysis and room air levels of delta-9-tetrahydrocannabinol. J. Anal. Toxicol. 1987, 11:89-96.
36. Hayden J.W. Passive inhalation of marijuana smoke: a critical review. J. Subst. Abuse 1991, 3:85-90.
37. Skopp G., Richter B., Potsch L. Serum cannabinoid levels 24 to 48hours after cannabis smoking. Arch. Kriminol. 2003, 212:83-95.
38. Ramaekers J.G., Robbe H.W., O'Hanlon J.F. Marijuana, alcohol and actual driving performance. Hum. Psychopharmacol. 2000, 15:551-558.
39. Schulz M., Schmoldt A. Therapeutic and toxic blood concentrations of more than 800 drugs and other xenobiotics. Pharmazie 2003, 58:447-474.
40. Winek C.L., Wahba W.W., Winek C.L., Balzer T.W. Drug and chemical blood-level data 2001. Forensic Sci. Int. 2001, 122:107-123.
41. Christophersen A.S., Morland J. Frequent detection of benzodiazepines in drugged drivers in Norway. Traffic Inj. Prev. 2008, 9:98-104.