Acute lung injury in patients with traumatic injuries: Utility of a panel of biomarkers for diagnosis and pathogenesis

Journal of Trauma - Injury, Infection and Critical Care

Volumn 68, Issue 5, 2010, Pages 1121-1127

  Fremont, Richard D ^a   Koyama, Tatsuki ^a   Calfee, Carolyn S ^b   Wu, William ^a   Dossett, Lesly A ^a   Bossert, Fred R ^a   Mitchell, Daphne ^a   Wickersham, Nancy ^a   Bernard, Gordon R ^a   Matthay, Michael A ^b   May, Addison K ^a   Ware, Lorraine B ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute pulmonary edema; Acute respiratory distress syndrome; Alveolar epithelium; Pulmonary contusion

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ANGIOPOIETIN 2; BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; INTERLEUKIN 10; INTERLEUKIN 8; PROCOLLAGEN; PROCOLLAGEN PEPTIDE III; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; ARTIFICIAL VENTILATION; BLOOD CLOTTING; BLOOD SAMPLING; CASE CONTROL STUDY; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; EARLY INTERVENTION; ENDOTHELIUM INJURY; FEMALE; FIBRINOLYSIS; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; INFLAMMATION; INJURY SEVERITY; INTENSIVE CARE UNIT; LENGTH OF STAY; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; RISK FACTOR; SENSITIVITY AND SPECIFICITY;

ACUTE LUNG INJURY; ADULT; ANGIOPOIETIN-2; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CAUSALITY; COLLAGEN TYPE III; DISCRIMINANT ANALYSIS; FEMALE; HOSPITALS, UNIVERSITY; HUMANS; INTERLEUKIN-10; INTERLEUKIN-8; LENGTH OF STAY; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NATRIURETIC PEPTIDE, BRAIN; PREDICTIVE VALUE OF TESTS; RECEPTORS, IMMUNOLOGIC; RESPIRATION, ARTIFICIAL; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; TUMOR NECROSIS FACTOR-ALPHA; WOUNDS AND INJURIES;

EID: 77952280855     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3181c40728     Document Type: Article

References (57)

1. Calfee CS, Eisner MD, Ware LB, et al. Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med. 2007;35:2243-2250.
2. Stapleton RD, Wang BM, Hudson LD, Rubenfeld GD, Caldwell ES, Steinberg KP. Causes and timing of death in patients with ARDS. Chest. 2005;128:525-532.
3. Eisner M, Thompson T, Hudson L, et al. Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med. 2001;164:231-236.
4. Estenssoro E, Dubin A, Laffaire E, et al. Incidence, clinical course, and outcome in 217 patients with acute respiratory distress syndrome. Crit Care Med. 2002;30:2450-2456.
5. Hudson LD, Milberg JA, Anardi D, Maunder RJ. Clinical risks for development of the acute respiratory distress syndrome. Am J Respir Crit Care Med. 1995;151:293-301.
6. Rubenfeld GD, Caldwell E, Peabody E, et al. Incidence and outcomes of acute lung injury. N Engl J Med. 2005;353:1685-1693.
7. Ware LB, Matthay MA. Medical progress: the acute respiratory distress syndrome. N Engl J Med. 2000;342:1334-1349.
8. Bernard GR, Artigas A, Brigham KL, et al. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med. 1994;149:818-824. (Pubitemid 24082248)
9. Goss CH, Brower RG, Hudson LD, Rubenfeld GD, the ARDS Network. Incidence of acute lung injury in the United States. Crit Care Med. 2003;31:1607-1611.
10. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med. 2000;342:1301-1308.
11. Ware LB, Eisner MD, Thompson BT, Parsons P, Matthay MA, the Acute Respiratory Distress Syndrome Network. Significance of von Willebrand factor in septic and non-septic patients with acute lung injury. Am J Respir Crit Care Med. 2004;170:766-772.
12. McClintock D, Zhuo H, Wickersham N, et al. Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury. Crit Care. 2008;12:R41.
13. Rubin DB, Wiener-Kronish JP, Murray JF, et al. Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis. J Clin Invest. 1990;86:474-480.
14. Greene KE, Wright JR, Steinberg KP, et al. Serial changes in surfactantassociated proteins in lung and serum before and after onset of ARDS. Am J Respir Crit Care Med. 1999;160:1843-1850.
15. Uchida T, Shirasawa M, Ware LB, et al. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med. 2006;173:1008-1015.
16. Eisner MD, Parsons P, Matthay MA, Ware L, Greene K, the ARDS Network. Plasma surfactant protein levels and clinical outcomes in patients with acute lung injury. Thorax. 2003;58:983-988.
17. Prabhakaran P, Ware LB, White KE, Cross MT, Matthay MA, Olman MA. Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2003;285:L20-L28.
18. Matthay MA, Zimmerman GA. Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management. Am J Respir Cell Mol Biol. 2005;33:319-327.
19. Dossett LA, Heffernan D, Lightfoot M, et al. Obesity and pulmonary complications in critically injured adults. Chest. 2008;134:974-980.
20. Dossett LA, Swenson BR, Evans HL, Bonatti H, Sawyer RG, May AK. Serum estradiol concentration as a predictor of death in critically ill and injured adults. Surg Infect (Larchmt). 2008;9:41-48.
21. Dossett LA, Swenson BR, Heffernan D, et al. High levels of endogenous estrogens are associated with death in the critically injured adult. J Trauma. 2008;64:580-585.
22. May AK, Dossett LA, Norris PR, et al. Estradiol is associated with mortality in critically ill trauma and surgical patients. Crit Care Med. 2008;36:62-68.
23. Ware LB, Matthay MA. Clinical practice. Acute pulmonary edema. N Engl J Med. 2005;353:2788-2796.
24. Ely EW, Haponik EF. Using the chest radiograph to determine intravascular volume status. The role of vascular pedicle width. Chest. 2002;121:942-950.
25. Ely EW, Smith AC, Chiles C, et al. Radiologic determination of intravascular volume status using portable, digital chest radiography: a prospective investigation in 100 patients. Crit Care Med. 2001;29:1502-1512.
26. Knaus W, Wagner D, Draper E, et al. The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. Chest. 1991;100:1619-1636.
27. Baker SP, O'Neill B, Haddon W Jr, Long WB. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974;14:187-196.
28. Boyd CR, Tolson MA, Copes WS. Evaluating trauma care: the TRISS method. Trauma score and the injury severity score. J Trauma. 1987;27:370-378.
29. Milne EN, Pistolesi M, Miniati M, Giuntini C. The vascular pedicle of the heart and the vena azygos. Part I: the normal subject. Radiology. 1984;152:1-8. (Pubitemid 14083142)
30. Harrell F E J. Regression Modeling Strategies with Applications to Linear Models, Logistic Regression, and Survival Analysis. New York: Springer-Verlag New York, Inc.; 2001.
31. Effron B, Tibshirani R. An Introduction to the Bootstrap. New York: Chapmna & Hall; 1993.
32. Dicker RA, Morabito DJ, Pittet JF, Campbell AR, Mackersie RC. Acute respiratory distress syndrome criteria in trauma patients: why the definitions do not work. J Trauma. 2004;57:522-526;
33. Salim A, Martin M, Constantinou C. Acute respiratory distress syndrome in the trauma intensive care unit: morbid but not mortal. Arch Surg. 2006;141:655-658.
34. Salim A, Martin M, Brown C, et al. The presence of the adult respiratory distress syndrome does not worsen mortality or discharge disability in blunt trauma patients with severe traumatic brain injury. Injury. 2008;39:30-35.
35. Treggiari MM, Hudson LD, Martin DP, Weiss NS, Caldwell E, Rubenfeld G. Effect of acute lung injury and acute respiratory distress syndrome on outcome in critically ill trauma patients. Crit Care Med. 2004;32:327-331.
36. Vincent JL, Sakr Y, Sprung CL, et al. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med. 2006;34:344-353.
37. Albertine KH, Soulier MF, Wang Z, et al. Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol. 2002;161:1783-1796.
38. Bachofen M, Weibel ER. Alterations of the gas exchange apparatus in adult respiratory insufficiency associated with septicemia. Am Rev Respir Dis. 1977;116:589-615.
39. Calfee CS, Ware LB, Eisner MD, et al. Plasma receptor for advanced glycation end-products and clinical outcomes in acute lung injury. Thorax. 2008;63:1083-1089.
40. Frank JA, Gutierrez JA, Jones KD, Allen L, Dobbs L, Matthay MA. Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs. Am J Respir Crit Care Med. 2002;165:242-249.
41. Matthay MA, Wiener-Kronish JP. Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis. 1990;142:1250-1257.
42. Ware LB, Matthay MA. Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med. 2001;163:1376-1383.
43. Matthay MA, Folkesson HG, Clerici C. Lung epithelial fluid transport and the resolution of pulmonary edema. Physiol Rev. 2002;82:569-600.
44. Laffon M, Lu LN, Modelska K, Matthay MA, Pittet JF. alpha-Adrenergic blockade restores normal fluid transport capacity of alveolar epithelium after hemorrhagic shock. Am J Physiol. 1999;277(4 Pt 1): L760-L768.
45. Modelska K, Matthay MA, Brown L A S, Deutch E, Lu LN, Pittet JF. Inhibition of beta-adrenergic dependent alveolar epithelial clearance by oxidant mechanisms after hemorrhagic shock in rats. Am J Physiol. 1999;276:L844-L857.
46. Modelska K, Matthay MA, Pittet JF. Prolonged hemorrhagic shock in rats causes an oxidant mediated decrease in alveolar epithelial fluid transport capacity. Am J Respir Crit Care Med. 1998;157:A350.
47. Chesnutt AN, Matthay MA, Tibayan FA, Clark JG. Early detection of type III procollagen peptide in acute lung injury. Am J Respir Crit Care Med. 1997;156:840-845.
48. Low RB, Cutroneo KR, Davis GS, Giancola MS. Lavage type III procollagen N-terminal peptides in human pulmonary fibrosis and sarcoidosis. Lab Invest. 1983;48:755-759.
49. Low RB, Giancola MS, King TE Jr, Chapitis J, Vacek P, Davis GS. Serum and bronchoalveolar lavage of N-terminal type III procollagen peptides in idiopathic pulmonary fibrosis. Am Rev Respir Dis. 1992;146:701-706.
50. Raedsch R, Stiehl A, Sieg A, Walker S, Kommerell B. Biliary excretion of procollagen type III peptide in healthy humans and in patients with alcoholic cirrhosis of the liver. Gastroenterology. 1983;85:1265-1270.
51. Weber KT. Monitoring tissue repair and fibrosis from a distance. Circulation. 1997;96:2488-2492.
52. Clark JG, Milberg JA, Steinberg KP, Hudson LD. Type III procollagen peptide in the adult respiratory distress syndrome. Ann Intern Med. 1995;122:17-23.
53. Meduri GU, Tolley EA, Chinn A, Stentz F, Postlethwaite A. Procollagen types I and III aminoterminal propeptide levels during acute respiratory distress syndrome and in response to methylprednisolone treatment. Am J Respir Crit Care Med. 1998;158:1432-1441.
54. Marshall R, Bellingan G, Webb S, et al. Fibroproliferation occurs early in the acute respiratory distress syndrome and impacts on outcome. Am J Respir Crit Care Med. 2000;162:1783-1788.
55. Waydhas C, Nast-Kolb D, Trupka A, et al. Increased serum concentrations of procollagen type III peptide in severely injured patients: an indicator of fibrosing activity? Crit Care Med. 1993;21:240-247
56. Wiedemann HP, Wheeler AP, Bernard GR, et al. Comparison of two fluid-management strategies in acute lung injury. N Engl J Med. 2006;354:2564-2575.
57. Cohn SM. Pulmonary contusion: review of the clinical entity. J Trauma. 1997;42:973-979.