Evaluation of the toxic effect of star fruit on serum biochemical parameters in rats

Pharmacognosy Magazine

Volumn 6, Issue 22, 2010, Pages 120-124

  Khoo, Z Y ^a   Teh, C C ^a   Rao, N K ^a   Chin, J H ^a  

^a UCSI UNIVERSITY   (Malaysia)

Author keywords

LD50; Liver; Oral toxicity; Serum enzyme; Star fruit

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; AVERRHOA CARAMBOLA EXTRACT; CREATININE; PLANT EXTRACT; UNCLASSIFIED DRUG; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AVERRHOA CARAMBOLA; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; FEMALE; FLUID INTAKE; FOOD INTAKE; FRUIT; FRUIT JUICE; KIDNEY FUNCTION; LD 50; LIVER FUNCTION; NONHUMAN; RAT; UREA BLOOD LEVEL;

EID: 77952268917     PISSN: 09731296     EISSN: None     Source Type: Journal    
DOI: 10.4103/0973-1296.62899     Document Type: Article

References (17)

1. Chang CH, Yeh JH. Non-convulsive status epilepticus and consciousness disturbance after star fruit (Averrhoa carambola) ingestion in a dialysis patient. J Nephrol 2004;9:362-365
2. Tse KC, Yip PS, Lam MF, Choy BY, Li FK, Lui SL, et al. Star fruit intoxication in uraemic patients: Case series and review of the literature. Intern Med J 2003;33:314-316
3. Shui G, Leong LP. Analysis of polyphenolic antioxidants in star fruit using liquid chromatography and mass spectrometry. J Chromotogr A 2004;1022:67-75.
4. Shui G, Leong LP. Residue from star fruit as valuable source for functional food ingredients and antioxidant nutraceuticals. Food Chem 2006;97:277-284
5. Chang CT, Chen YC, Fang JT, Huang CC. Star fruit (Averrhoa carambola) intoxication: An important cause of consciousness disturbance in patients with renal failure. Ren Fail 2002;24:379-382
6. Fang HC, Chen CL, Lee PT, Hsu CT, Tseng CJ, Lu PJ, et al. The role of oxalate in star fruit neurotoxicity of five-sixths nephrectomized rats. Food Chem Tox 2007;45:1764-1769
7. Hou CY, Lin YS, Wang YT, Jiang CM, Wu MC. Effect of storage conditions on methanol content of fruit and vegetables juice. J Food Comp Anal 2008;21:410-415
8. Levine BS. Animal clinical pathology. In: Derelanko MJ, Hollinger MA, editors. CRC handbook of toxicology. USA: CRC Press; 1995. p. 517-539
9. Ecobichon DJ. The basis of toxicity testing. Baca Raton: CRC Press; 1995.
10. Lu FC, Kacew S. Lu's basic toxicology. 4th ed. London: Taylor and Francis; 2002. p. 189,90,204.
11. Negishi M, Aida K, Yoshioka H. Sexually dimorphic expression of P-450 genes. In: Omura T, Ishimura Y, Fujii-Kuriyama Y, editors. Cytochrome P-450, Weinheim: VCH; 1993. p. 230-238
12. Ramaiah SK. A toxicologist guide to the diagnostic interpretation of hepatic biochemical parameters. Food Chem Tox 2007;45:1551-1557
13. Tortora GJ, Derrickson B. Principles of anatomy and physiology. 11th ed. USA: John Wiley and Sons, Inc; 2006.
14. Treichel JL, Henry MM, Skumatz CM, Eells JT, Burke JM. Antioxidants and ocular cell type differences in cytoprotection from formic acid in vitro. Tox Sci 2004;82:183-192
15. Dufour DR, Lott JA, Nolte FS, Gretch DR, Koff RS, Seeff LB. Diagnosis and monitoring of hepatic injury, II: Recommendations for use of laboratory tests in screening, diagnosis, and monitoring. Clin Chem 2000;46:2050-2068
16. Zhang X. General guideline for methodologies on research and evaluation of traditional medicine. Geneva: World Health Organization (WHO); 2000.
17. Barrow P. Reproduction and development of toxicology safety studies. In: Krinke GJ, editor. The handbook of experimental animals: the laboratory rats. United Kingdom: Academic Press; 2000. p. 11-27.