Regulation of hemagglutinin/protease expression by the VarS/VarA-CsrA/B/C/D system in Vibrio cholerae

Microbial Pathogenesis

Volumn 48, Issue 6, 2010, Pages 245-250

  Jang, Jeyoun ^a   Jung, Kyung Tae ^a   Yoo, Cheon Kwon ^a   Rhie, Gi eun ^a  

^a Korea National Institute of Health   (South Korea)

Author keywords

s; Hemagglutinin protease A; VarA; VarS; Vibrio cholerae

Indexed keywords

CHOLERA TOXIN B SUBUNIT; HEMAGGLUTININ; PROTEIN CSRA; PROTEIN CSRB; PROTEIN CSRC; PROTEIN CSRD; PROTEIN HAPA; PROTEIN HAPR; PROTEIN VARA; PROTEIN VARS; PROTEINASE; SIGMA FACTOR; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ADAPTATION; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOFILM; DNA FLANKING REGION; ENVIRONMENTAL STRESS; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENE INSERTION; GENETIC ANALYSIS; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; TRANSPOSON; VIBRIO CHOLERAE;

BACTERIAL PROTEINS; BIOFILMS; CHOLERA TOXIN; GENE EXPRESSION REGULATION, BACTERIAL; METALLOENDOPEPTIDASES; MUTATION; PROMOTER REGIONS, GENETIC; SIGMA FACTOR; VIBRIO CHOLERAE;

VIBRIO CHOLERAE;

EID: 77952236520     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2010.03.003     Document Type: Article

References (35)

1. Faruque S.M., Albert M.J., Mekalanos J.J. Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae. Microbiol Mol Biol Rev 1998, 62:1301-1314.
2. Spangler B.D. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol Rev 1992, 56:622-647.
3. Lencer W.I., Tsai B. The intracellular voyage of cholera toxin: going retro. Trends Biochem Sci 2003, 28:639-645.
4. Booth B.A., Boesman-Finkelstein M., Finkelstein R.A. Vibrio cholerae soluble hemagglutinin/protease is a metalloenzyme. Infect Immun 1983, 42:639-644.
5. Reidl J., Klose K.E. Vibrio cholerae and cholera: out of the water and into the host. FEMS Microbiol Rev 2002, 26:125-139.
6. Wu Z., Milton D., Nybom P., Sjö A., Magnusson K.E. Vibrio cholerae hemagglutinin/protease (HA/protease) causes morphological changes in cultured epithelial cells and perturbs their paracellular barrier function. Microb Pathog 1996, 21:111-123.
7. Wu Z., Nybom P., Magnusson K.E. Distinct effects of Vibrio cholerae hemagglutinin/protease on the structure and localization of the tight junction-associated proteins occludin and ZO-1. Cell Microbiol 2000, 2:11-17.
8. Mel S.F., Fullner K.J., Wimer-Mackin S., Lencer W.I., Mekalanos J.J. Association of protease activity in Vibrio cholerae vaccine strains with decreases in transcellular epithelial resistance of polarized T84 intestinal epithelial cells. Infect Immun 2000, 68:6487-6492.
9. Finkelstein R.A., Boesman-Finkelstein M., Chang Y., Häse C.C. Vibrio cholerae hemagglutinin/protease, colonial variation, virulence, and detachment. Infect Immun 1992, 60:472-478.
10. Häse C.C., Finkelstein R.A. Cloning and nucleotide sequence of the Vibrio cholerae hemagglutinin/protease(HA/protease) gene and construction of an HA/protease-negative strain. J Bacteriol 1991, 173:3311-3317.
11. Booth B.A., Boesman-Finkelstein M., Finkelstein R.A. Vibrio cholerae hemagglutinin/protease nicks cholera enterotoxin. Infect Immun 1984, 45:558-560.
12. Nagamune K., Yamamoto K., Naka A., Matsuyama J., Miwatani T., Honda T. In vitro proteolytic processing and activation of the recombinant precursor of El Tor cytolysin/hemolysin (pro-HlyA) of Vibrio cholerae by soluble hemagglutinin/protease of V. cholerae, trypsin, and other proteases. Infect Immun 1996, 64:4655-4658.
13. Finkelstein R.A., Boesman-Finkelstein M., Holt P. Vibrio cholerae hemagglutinin/lectin/protease hydrolyzes fibronectin and ovomucin: F.M. Burnet revisited. Proc Natl Acad Sci USA 1983, 80:1092-1095.
14. Hammer B.K., Bassler B.L. Quorum sensing controls biofilm formation in Vibrio cholerae. Mol Microbiol 2003, 50:101-104.
15. Lenz D.H., Mok K.C., Lilley B.N., Kulkarni R.V., Wingreen N.S., Bassler B.L. The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae. Cell 2004, 118:69-82.
16. Chen X., Schauder S., Potier N., Van Dorsselaer A., Pelczer I., Bassler B.L., et al. Structural identification of a bacterial quorum-sensing signal containing boron. Nature 2002, 415:545-549.
17. Lenz D.H., Miller M.B., Zhu J., Kulkarni R.V., Bassler B.L. CsrA and three redundant small RNAs regulate quorum sensing in Vibrio cholerae. Mol Microbiol 2005, 58:1186-1202.
18. Lenz D.H., Bassler B.L. The small nucleoid protein Fis is involved in Vibrio cholerae quorum sensing. Mol Microbiol 2007, 63:859-871.
19. Zhu J., Miller M.B., Vance R.E., Dziejman M., Bassler B.L., Mekalanos J.J. Quorum-sensing regulators control virulence gene expression in Vibrio cholerae. Proc Natl Acad Sci USA 2002, 99:3129-3134.
20. Jobling M.G., Holmes R.K. Characterization of hapR, a positive regulator of the Vibrio cholerae HA/protease gene hap, and its identification as a functional homologue of the Vibrio harveyi luxR gene. Mol Microbiol 1997, 26:1023-1034.
21. Rhie G., Jung H., Park J., Kim B., Mekalanos J.J. Construction of cholera toxin B subunit-producing Vibrio cholerae strains using the Mariner-FRT transposon delivery system. FEMS Immun Med Microbiol 2008, 52:23-28.
22. Mohapatra S.S., Ramachandran D., Mantri C.K., Colwell R.R., Singh D.V. Determination of relationships among non-toxigenic Vibrio cholerae O1 biotype El Tor strains from housekeeping gene sequences and ribotype patterns. Res Microbiol 2009, 160:57-62.
23. Yildiz F.H., Schoolnik G.K. Role of rpoS in stress survival and virulence of Vibrio cholerae. J Bacteriol 1998, 180:773-784.
24. Moolenaar G.F., van Sluis C.A., Backendorf C., van de Putte P. Regulation of the Escherichia coli excision repair gene uvrC. Overlap between the uvrC structural gene and the region coding for a 24 kD protein. Nucleic Acids Res 1987, 15:4273-4289.
25. Rahme L.G., Tan M.W., Le L., Wong S.M., Tompkins R.G., Calderwood S.B., et al. Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc Natl Acad Sci USA 1997, 94:13245-13250.
26. Reimmann C., Beyeler M., Latifi A., Winteler H., Foglino M., Lazdunski A., et al. The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipase. Mol Microbiol 1997, 24:309-319.
27. Johnston C., Pegues D.A., Hueck C.J., Lee A., Miller S.I. Transcriptional activation of Salmonella typhimurium invasion genes by a member of the phosphorylated response-regulator superfamily. Mol Microbiol 1996, 22:715-727.
28. Sacherer P., Défago G., Haas D. Extracellular protease and phospholipase C are controlled by the global regulatory gene gacA in the biocontrol strain Pseudomonas fluorescens CHAO. FEMS Microbiol Lett 1994, 116:155-160.
29. Wong S.M., Carroll P.A., Rahme L.G., Ausubel F.M., Calderwood S.B. Modulation of expression of the ToxR regulon in Vibrio cholerae by a member of the two-component family of response regulators. Infect Immun 1998, 66:5854-5861.
30. Lilley B.N., Bassler B.L. Regulation of quorum sensing in Vibrio harveyi by LuxO and Sigma-54. Mol Microbiol 2000, 36:940-954.
31. Current protocols in molecular biology 1995, Wiley, New York. F.M. Ausubel, R. Brent, R.E. Kingston, D.E. Moore, J.G. Seidman, J.A. Smith, K. Struhl (Eds.).
32. Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L., Dodson R.J., et al. DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature 2000, 406:477-483.
33. Donnenberg M.S., Kaper J.B. Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector. Infect Immun 1991, 59:4310-4317.
34. Simon R., Priefer U., Pühler A. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria. Nature Biotechnology 1983, 1:784-791.
35. Benitez J.A., Silva A.J., Finkelstein R.A. Environmental signals controlling production of hemagglutinin/protease in Vibrio cholerae. Infect Immun 2001, 69:6549-6553.