메뉴 건너뛰기




Volumn 45, Issue 3, 2010, Pages 318-323

Apoptosis-inducing effect of cinobufacini on human hepatoma cell line HepG 2 and its mechanism of action

Author keywords

Apoptosis; Cinobufacini; Human hepatoma cell line HepG 2; Proliferation

Indexed keywords

ANTINEOPLASTIC AGENT; CINOBUFACINI; HUACHANSU; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 77952212096     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (18)

References (17)
  • 1
    • 66749090417 scopus 로고    scopus 로고
    • Studies on the chemical constituents from the skin Bufo bufo gargarizans Cantor
    • [J]
    • Yang LH, Jin XQ, Zhang W. Studies on the chemical constituents from the skin Bufo bufo gargarizans Cantor [J]. J Shenyang Pharm Univ, 2000, 17: 292-295.
    • (2000) J Shenyang Pharm Univ , vol.17 , pp. 292-295
    • Yang, L.H.1    Jin, X.Q.2    Zhang, W.3
  • 2
    • 70449339430 scopus 로고    scopus 로고
    • Research on the effect of cinobufacini on human gastric neoplasm cell line MGC-80-3
    • [J]
    • Zuo XD, Cui YA, Wang JH, et al. Research on the effect of cinobufacini on human gastric neoplasm cell line MGC-80-3 [J]. Chin Clin Oncol, 2003, 8: 33-35.
    • (2003) Chin Clin Oncol , vol.8 , pp. 33-35
    • Zuo, X.D.1    Cui, Y.A.2    Wang, J.H.3
  • 3
    • 77952180270 scopus 로고    scopus 로고
    • Effect of cinobufacini on Jurkat cell line in vitro and in the animal experiment
    • [J]
    • Wang Y, Li JM, Zhang L, et al. Effect of cinobufacini on Jurkat cell line in vitro and in the animal experiment [J]. J Diagn Concept Pract, 2005, 4: 308-312.
    • (2005) J Diagn Concept Pract , vol.4 , pp. 308-312
    • Wang, Y.1    Li, J.M.2    Zhang, L.3
  • 4
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • -ΔΔCT method [J]. Methods, 2001, 25: 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 5
    • 58849136702 scopus 로고    scopus 로고
    • Molecular targeted therapy for hepatocellular carcinoma
    • [J]
    • Thomas M. Molecular targeted therapy for hepatocellular carcinoma [J]. J Gastroenterol, 2009, 19: 136-141.
    • (2009) J Gastroenterol , vol.19 , pp. 136-141
    • Thomas, M.1
  • 6
    • 77952121393 scopus 로고    scopus 로고
    • The state Pharmacopoeia Committee of the People's Republic of China. Beijing: Chemical Industry Press
    • The state Pharmacopoeia Committee of the People's Republic of China. Chinese Pharmacopoeia 2005 2005 [M]. Beijing: Chemical Industry Press, 2005: 265-266.
    • (2005) Chinese Pharmacopoeia 2005 2005 [M] , pp. 265-266
  • 7
    • 77952162186 scopus 로고    scopus 로고
    • Toad'toxic and side effect on the circulatory system of experimental animals
    • [J]
    • Qian WP. Toad'toxic and side effect on the circulatory system of experimental animals [J]. J Zhejiang Tradit Chin Med Coll, 2001, 25: 46-47.
    • (2001) J Zhejiang Tradit Chin Med Coll , vol.25 , pp. 46-47
    • Qian, W.P.1
  • 8
    • 34447321283 scopus 로고    scopus 로고
    • Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumor model of human hepatocellular carcinoma in nude mice
    • Han KQ, Huang G, Gu W, et al. Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumor model of human hepatocellular carcinoma in nude mice [J]. World J Gastroenterol, 2007, 13: 3374-3379. (Pubitemid 47062250)
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.24 , pp. 3374-3379
    • Han, K.-Q.1    Huang, G.2    Gu, W.3    Su, Y.-H.4    Huang, X.-Q.5    Ling, C.-Q.6
  • 9
    • 77951179825 scopus 로고    scopus 로고
    • Apoptosis-inducing effect of Cinobufacini, Bufo bufo gargarizans Cantor skin extract, on human hepatoma cell line BEL-7402
    • [J]
    • Qi FH, Li AY, Gao B, et al. Apoptosis-inducing effect of Cinobufacini, Bufo bufo gargarizans Cantor skin extract, on human hepatoma cell line BEL-7402 [J]. Drug Discov Ther, 2008, 6: 339-343.
    • (2008) Drug Discov Ther , vol.6 , pp. 339-343
    • Qi, F.H.1    Li, A.Y.2    Gao, B.3
  • 10
    • 46449105600 scopus 로고    scopus 로고
    • Bufalin induces growth inhibition, cell cycle arrest and apoptosis in human endometrial and ovarian cancer cells
    • [J]
    • Takai N, Ueda T, Nishida M, et al. Bufalin induces growth inhibition, cell cycle arrest and apoptosis in human endometrial and ovarian cancer cells [J]. Int J Mol Med, 2008, 21: 637-643.
    • (2008) Int J Mol Med , vol.21 , pp. 637-643
    • Takai, N.1    Ueda, T.2    Nishida, M.3
  • 11
    • 33646417201 scopus 로고    scopus 로고
    • Inhibition effects of three kinds of bufotoxins on human SMMC-7721 and BEL-7402 hepatoma cell lines
    • [J]
    • Su YH, Yin XC, Xie JM, et al. Inhibition effects of three kinds of bufotoxins on human SMMC-7721 and BEL-7402 hepatoma cell lines [J]. Acad J Sec Mil Med Univ, 2003, 24: 393-395.
    • (2003) Acad J Sec Mil Med Univ , vol.24 , pp. 393-395
    • Su, Y.H.1    Yin, X.C.2    Xie, J.M.3
  • 12
    • 54949132875 scopus 로고    scopus 로고
    • Bcl-2 family proteins and cancer
    • [J]
    • Yip KW, Reed JC. Bcl-2 family proteins and cancer [J]. Oncogene, 2008, 27: 6398-6406.
    • (2008) Oncogene , vol.27 , pp. 6398-6406
    • Yip, K.W.1    Reed, J.C.2
  • 13
    • 33847727026 scopus 로고    scopus 로고
    • Effect of ZGDHu-1 on proliferation and apoptosis of A549 cells in vitro and antitumor activity in vivo
    • [J]
    • Zhou YL, Hu WX, LO YP, et al. Effect of ZGDHu-1 on proliferation and apoptosis of A549 cells in vitro and antitumor activity in vivo [J]. Acta Pharm Sin, 2007, 42: 26-34.
    • (2007) Acta Pharm Sin , vol.42 , pp. 26-34
    • Zhou, Y.L.1    Hu, W.X.2    Lo, Y.P.3
  • 14
    • 33544472649 scopus 로고    scopus 로고
    • Vitexicarpin, a flavonoid from Vitex trifolia L., induces apoptosis in K562 cells via mitochondria-controlled apoptotic pathway
    • [J]
    • Wang HY, Cai B, Cui CB, et al. Vitexicarpin, a flavonoid from Vitex trifolia L., induces apoptosis in K562 cells via mitochondria-controlled apoptotic pathway [J]. Acta Pharm Sin, 2005, 40: 27-31.
    • (2005) Acta Pharm Sin , vol.40 , pp. 27-31
    • Wang, H.Y.1    Cai, B.2    Cui, C.B.3
  • 15
    • 32644473650 scopus 로고    scopus 로고
    • How the Bcl-2 family of proteins interact to regulate apoptosis
    • [J]
    • Van Delft MF, Huang DC. How the Bcl-2 family of proteins interact to regulate apoptosis [J]. Cell Res, 2006, 16: 203-213.
    • (2006) Cell Res , vol.16 , pp. 203-213
    • Van Delft, M.F.1    Huang, D.C.2
  • 16
    • 33745244111 scopus 로고    scopus 로고
    • Restoring p53-mediated apoptosis in cancer cells: New opportunities for cancer therapy
    • DOI 10.1016/j.drup.2006.03.001, PII S1368764606000197
    • Yu Q. Restoring p53-mediated apoptosis in cancer cells: new opportunities for cancer therapy [J]. Drug Resist Updat, 2006, 9: 19-25. (Pubitemid 43928803)
    • (2006) Drug Resistance Updates , vol.9 , Issue.1-2 , pp. 19-25
    • Yu, Q.1
  • 17
    • 0842278331 scopus 로고    scopus 로고
    • Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
    • DOI 10.1126/science.1092734
    • Chipuk JE, Kuwana T, Bouchier-Hayes L, et al. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis [J]. Science, 2004, 303: 1010-1014. (Pubitemid 38209704)
    • (2004) Science , vol.303 , Issue.5660 , pp. 1010-1014
    • Chipuk, J.E.1    Kuwana, T.2    Bouchier-Hayes, L.3    Droin, N.M.4    Newmeyer, D.D.5    Schuler, M.6    Green, D.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.