Crystal structure of HLA-DP2 and implications for chronic beryllium disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 16, 2010, Pages 7425-7430

  Dai, Shaodong ^a   Murphy, Guinevere A ^a,d   Crawford, Frances ^a   Mack, Douglas G ^b   Falta, Michael T ^b   Marrack, Philippa ^a,c   Kappler, John W ^a,c   Fontenot, Andrew P ^a,b  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d ARCA Biopharma   (United States)

Author keywords

Antigen presentation; Lung disease; Metal hypersensitivity

Indexed keywords

ARGININE; BERYLLIUM; CD4 ANTIGEN; GLUTAMIC ACID; HLA ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN HLA DP2; UNCLASSIFIED DRUG;

ACIDITY; ALLELE; ALPHA CHAIN; ALPHA HELIX; ANTIGEN BINDING; ARTICLE; BERYLLIOSIS; BETA CHAIN; BINDING SITE; CD4+ T LYMPHOCYTE; CRYSTAL STRUCTURE; EXPOSURE; GENE; GENETIC SUSCEPTIBILITY; GRANULOMATOUS INFLAMMATION; HLA DPB1 GENE; HYDROGEN BOND; LUNG FIBROSIS; MUTATION; PRIORITY JOURNAL;

ALLELES; ANIMALS; BERYLLIOSIS; CD4-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; CRYSTALLOGRAPHY, X-RAY; GLUTAMIC ACID; HLA-DP ANTIGENS; HUMANS; LUNG DISEASES; MICE; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY;

EID: 77952195430     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1001772107     Document Type: Article

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