Embryonic trafficking of γδ T cells to skin is dependent on E/P selectin ligands and CCR4

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 16, 2010, Pages 7443-7448

  Jiang, Xiaodong ^a   Campbell, James J ^a   Kupper, Thomas S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Dendritic epidermal T cells; Skin T cells; T cell trafficking

Indexed keywords

CHEMOKINE RECEPTOR CCR4; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1 LIGAND; LIGAND; PADGEM PROTEIN; PADGEM PROTEIN LIGAND; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR VDELTA1; T LYMPHOCYTE RECEPTOR VGAMMA3; UNCLASSIFIED DRUG; CCR10 PROTEIN, MOUSE; CCR4 PROTEIN, MOUSE; CHEMOKINE RECEPTOR CCR10; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DENDRITIC EPIDERMAL T LYMPHOCYTE; EMBRYO; EPIDERMIS; LYMPHOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN; T LYMPHOCYTE SUBPOPULATION; THYMUS; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CYTOLOGY; GENE EXPRESSION REGULATION; METABOLISM; PRENATAL DEVELOPMENT; T LYMPHOCYTE; TRANSGENIC MOUSE;

MUS;

ANIMALS; E-SELECTIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LIGANDS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, BIOLOGICAL; P-SELECTIN; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, CCR10; RECEPTORS, CCR4; SKIN; T-LYMPHOCYTES;

EID: 77952172646     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0912943107     Document Type: Article

References (36)

1. Saito H, et al. (1984) Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences. Nature 309:757-762. (Pubitemid 14119426)
2. Hayday AC, et al. (1985) Structure, organization, and somatic rearrangement of T cell gamma genes. Cell 40:259-269.
3. Brenner MB, et al. (1986) Identification of a putative second T-cell receptor. Nature 322:145-149.
4. Nanno M, Shiohara T, Yamamoto H, Kawakami K, Ishikawa H (2007) gammadelta T cells: Firefighters or fire boosters in the front lines of inflammatory responses. Immunol Rev 215:103-113. (Pubitemid 46212233)
5. Payer E, Elbe A, Stingl G (1992) Epidermal T lymphocytes - ontogeny, features and function. Springer Semin Immunopathol 13:315-331.
6. Jameson J, et al. (2002) A role for skin gammadelta T cells in wound repair. Science 296:747-749. (Pubitemid 34442005)
7. Sharp LL, Jameson JM, Cauvi G, Havran WL (2005) Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1. Nat Immunol 6:73-79. (Pubitemid 40136698)
8. Jameson J, Havran WL (2007) Skin gammadelta T-cell functions in homeostasis and wound healing. Immunol Rev 215:114-122. (Pubitemid 46212234)
9. Strid J, et al. (2008) Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis. Nat Immunol 9:146-154.
10. Girardi M (2006) Immunosurveillance and immunoregulation by gammadelta T cells. J Invest Dermatol 126:25-31.
11. Takashima A, Bergstresser PR (1996) Cytokine-mediated communication by keratinocytes and Langerhans cells withdendriticepidermalT cells. SeminImmunol 8:333-339. (Pubitemid 26418371)
12. Havran WL, Allison JP (1988) Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors. Nature 335:443-445.
13. Havran WL, Allison JP (1990) Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors. Nature 344:68-70. (Pubitemid 20073237)
14. Xiong N, Raulet DH (2007) Development and selection of gammadelta T cells. Immunol Rev 215:15-31.
15. Lewis JM, et al. (2006) Selection of the cutaneous intraepithelial gammadelta+ T cell repertoire by a thymic stromal determinant. Nat Immunol 7:843-850.
16. Jensen KD, et al. (2008) Thymic selection determines gammadelta T cell effector fate: Antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma. Immunity 29:90-100.
17. Weinreich MA, Hogquist KA (2008) Thymic emigration: When and how T cells leave home. J Immunol 181:2265-2270.
18. Xiong N, Kang C, Raulet DH (2004) Positive selection of dendritic epidermal gammadelta T cell precursors in the fetal thymus determines expression of skin-homing receptors. Immunity 21:121-131. (Pubitemid 38930834)
19. Mora JR, von Andrian UH (2006) T-cell homing specificity and plasticity: New concepts and future challenges. Trends Immunol 27:235-243.
20. Austrup F, et al. (1997) P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature 385:81-83. (Pubitemid 27024558)
21. Reiss Y, Proudfoot AE, Power CA, Campbell JJ, Butcher EC (2001) CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin. J Exp Med 194:1541-1547. (Pubitemid 33081528)
22. Marelli-Berg FM, Cannella L, Dazzi F, Mirenda V (2008) The highway code of T cell trafficking. J Pathol 214:179-189.
23. Chong BF, Murphy JE, Kupper TS, Fuhlbrigge RC (2004) E-selectin, thymus- and activation-regulated chemokine/CCL17, and intercellular adhesion molecule-1 are constitutively coexpressed in dermal microvessels: A foundation for a cutaneous immunosurveillance system. J Immunol 172:1575-1581.
24. Ley K, Kansas GS (2004) Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation. Nat Rev Immunol 4:325-335. (Pubitemid 38649275)
25. Barthel SR, Gavino JD, Descheny L, Dimitroff CJ (2007) Targeting selectins and selectin ligands in inflammation and cancer. Expert Opin Ther Targets 11:1473-1491. (Pubitemid 350200482)
26. Campbell JJ, O'Connell DJ, Wurbel MA (2007) Cutting edge: Chemokine receptor CCR4 is necessary for antigen-driven cutaneous accumulation of CD4 T cells under physiological conditions. J Immunol 178:3358-3362.
27. Soler D, Humphreys TL, Spinola SM, Campbell JJ (2003) CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking. Blood 101:1677-1682. (Pubitemid 36237558)
28. Bromley SK, Mempel TR, LusterAD (2008) Orchestrating the orchestrators: Chemokines in control of T cell traffic. Nat Immunol 9:970-980.
29. Bergstresser PR, Tigelaar RE, Dees JH, Streilein JW (1983) Thy-1 antigen-bearing dendritic cells populate murine epidermis. J Invest Dermatol 81:286-288.
30. Tschachler E, et al. (1983) Expression of Thy-1 antigen by murine epidermal cells. J Invest Dermatol 81:282-285. (Pubitemid 13050581)
31. Smithson G, et al. (2001) Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes. J Exp Med 194:601-614. (Pubitemid 32844771)
32. Staite ND, Justen JM, Sly LM, Beaudet AL, Bullard DC (1996) Inhibition of delayed-type contact hypersensitivity in mice deficient in both E-selectin and P-selectin. Blood 88:2973-2979. (Pubitemid 26357378)
33. Ley K, Laudanna C, Cybulsky MI, Nourshargh S (2007) Getting to the site of inflammation: The leukocyte adhesion cascade updated. Nat Rev Immunol 7:678-689. (Pubitemid 47327397)
34. Yoshida R, et al. (1998) EBI1-ligand chemokine (ELC) attracts a broad spectrum of lymphocytes: Activated T cells strongly up-regulate CCR7 and efficiently migrate toward ELC. Int Immunol 10:901-910. (Pubitemid 28325606)
35. De Creus A, et al. (2002) Developmental and functional defects of thymic and epidermal V γ 3 cells in IL-15-deficient and IFN regulatory factor-1-deficient mice. J Immunol 168:6486-6493. (Pubitemid 34620074)
36. Clark RA, et al. (2006) The vast majority of CLA+ T cells are resident in normal skin. J Immunol 176:4431-4439. (Pubitemid 44264423)