-
2
-
-
35348979730
-
Incidence and outcome of traumatic brain injury in an urban area in Western Europe over 10 years
-
Maegele M, Engel D, Bouillon B, et al. Incidence and outcome of traumatic brain injury in an urban area in Western Europe over 10 years. Eur Surg Res 2007;39:372-379.
-
(2007)
Eur. Surg. Res.
, vol.39
, pp. 372-379
-
-
Maegele, M.1
Engel, D.2
Bouillon, B.3
-
3
-
-
0038163876
-
Therapeutic hypothermia after cardiac arrest: An advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation
-
Nolan JP, Morley PT, Vanden Hoek TL, et al. Therapeutic hypothermia after cardiac arrest: an advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation. Circulation 2003;108:118-121.
-
(2003)
Circulation
, vol.108
, pp. 118-121
-
-
Nolan, J.P.1
Morley, P.T.2
Vanden Hoek, T.L.3
-
4
-
-
33745610728
-
From evidence to clinical practice: Effective implementation of therapeutic hypothermia to improve patient outcome after cardiac arrest
-
Oddo M, Schaller MD, Feihl F, et al. From evidence to clinical practice: effective implementation of therapeutic hypothermia to improve patient outcome after cardiac arrest. Crit Care Med 2006;34:1865-1873.
-
(2006)
Crit. Care Med.
, vol.34
, pp. 1865-1873
-
-
Oddo, M.1
Schaller, M.D.2
Feihl, F.3
-
6
-
-
34948820813
-
Hypothermia to treat neonatal hypoxic ischemic encephalopathy: A systematic review
-
Shah PS, Ohlsson A, Perlman M. Hypothermia to treat neonatal hypoxic ischemic encephalopathy: a systematic review. Arch Pediatr Adolesc Med 2007;161:951-958.
-
(2007)
Arch. Pediatr. Adolesc. Med.
, vol.161
, pp. 951-958
-
-
Shah, P.S.1
Ohlsson, A.2
Perlman, M.3
-
7
-
-
35448977629
-
A systematic review of cooling for neuroprotection in neonates with hypoxic ischemic encephalopathy: Are we there yet?
-
Schulzke SM, Rao S, Patole SK. A systematic review of cooling for neuroprotection in neonates with hypoxic ischemic encephalopathy: are we there yet? BMC Pediatr 2007;7:30.
-
(2007)
BMC Pediatr.
, vol.7
, pp. 30
-
-
Schulzke, S.M.1
Rao, S.2
Patole, S.K.3
-
8
-
-
62649129002
-
Protection in animal models of brain and • spinal cord injury with mild to moderate hypothermia
-
Comprehensive review on neuroprotection induced by hypothermia in animal models of traumatic brain injury as well as spinal cord injury
-
Dietrich D, Atkins C, Bramlett H. Protection in animal models of brain and • spinal cord injury with mild to moderate hypothermia. J Neurotrauma 2009;26:301-312. Comprehensive review on neuroprotection induced by hypothermia in animal models of traumatic brain injury as well as spinal cord injury.
-
(2009)
J. Neurotrauma
, vol.26
, pp. 301-312
-
-
Dietrich, D.1
Atkins, C.2
Bramlett, H.3
-
9
-
-
38849108689
-
Rapid NMDA receptor phosphorylation and oxidative stress preced striatal neurodegeneration after hypoxic ischemia in newborn piglets and are attenuated with hypothermia
-
Mueller-Burke D, Koehler RC, Martin LJ. Rapid NMDA receptor phosphorylation and oxidative stress preced striatal neurodegeneration after hypoxic ischemia in newborn piglets and are attenuated with hypothermia. Int J Dev Neurosci 2008;26:67-76.
-
(2008)
Int. J. Dev. Neurosci.
, vol.26
, pp. 67-76
-
-
Mueller-Burke, D.1
Koehler, R.C.2
Martin, L.J.3
-
10
-
-
45849117222
-
Therapeutic effect of postischemic hypothermia duration on cerebral ischemic injury
-
Zhang H, Zhou M, Zhang J, et al. Therapeutic effect of postischemic hypothermia duration on cerebral ischemic injury. Neurol Res 2008;30:332-336.
-
(2008)
Neurol. Res.
, vol.30
, pp. 332-336
-
-
Zhang, H.1
Zhou, M.2
Zhang, J.3
-
11
-
-
37349030729
-
Minocycline and hypothermia for reperfusion injury after focal cerebral ischemia in the rat: Effects on BBB breakdown and MMP expression in the acute and subacute phase
-
Nagel S, Su Y, Horstmann S, et al. Minocycline and hypothermia for reperfusion injury after focal cerebral ischemia in the rat: effects on BBB breakdown and MMP expression in the acute and subacute phase. Brain Res 2008;1188:198-206.
-
(2008)
Brain Res.
, vol.1188
, pp. 198-206
-
-
Nagel, S.1
Su, Y.2
Horstmann, S.3
-
12
-
-
33846614162
-
εPKC may contribute to the protective effect of hypothermia in a rat focal cerebral ischemia model
-
DOI 10.1161/01.STR.0000254616.78387.ee, PII 0000767020070200000044
-
Shimohata T, Zhao H, Steinberg GK. Epsilon PKC may contribute to the protective effect of hypothermia in a rat focal cerebral ischemia model. Stroke 2007;38:375-380. (Pubitemid 46184309)
-
(2007)
Stroke
, vol.38
, Issue.2
, pp. 375-380
-
-
Shimohata, T.1
Zhao, H.2
Steinberg, G.K.3
-
13
-
-
34547111785
-
Suppression of δPKC activation after focal cerebral ischemia contributes to the protective effect of hypothermia
-
DOI 10.1038/sj.jcbfm.9600450, PII 9600450
-
Shimohata T, Zhao H, Sung JH, et al. Suppression of deltaPKC activation after focal cerebral ischemia contributes to the protective effect of hypothermia. J Cereb Blood Flow Metab 2007;27:1463-1475. (Pubitemid 47106606)
-
(2007)
Journal of Cerebral Blood Flow and Metabolism
, vol.27
, Issue.8
, pp. 1463-1475
-
-
Shimohata, T.1
Zhao, H.2
Sung, J.H.3
Sun, G.4
Mochly-Rosen, D.5
Steinberg, G.K.6
-
14
-
-
34548840827
-
Conditions of protection by hypothermia and effects on apoptotic pathways in a rat model of permanent middle cerebral artery occlusion
-
Zhao H, Wang JQ, Shimohata T, et al. Conditions of protection by hypothermia and effects on apoptotic pathways in a rat model of permanent middle cerebral artery occlusion. J Neurosurg 2007;107:636-641.
-
(2007)
J. Neurosurg.
, vol.107
, pp. 636-641
-
-
Zhao, H.1
Wang, J.Q.2
Shimohata, T.3
-
15
-
-
33847122561
-
Therapeutic time window of postischemic mild hypothermia and the gene expression associated with the neuroprotection in rat focal cerebral ischemia
-
Ohta H, Terao Y, Shintani Y, et al. Therapeutic time window of postischemic mild hypothermia and the gene expression associated with the neuroprotection in rat focal cerebral ischemia. Neurol Sci 2007;57:424-433.
-
(2007)
Neurol. Sci.
, vol.57
, pp. 424-433
-
-
Ohta, H.1
Terao, Y.2
Shintani, Y.3
-
16
-
-
38349167227
-
Analysis of neuronal, glial, endothelial, axonal and apoptotic markers following moderate therapeutic hypothermia and anesthesia in the developing piglet brain
-
Gressens P, Dingley J, Plaisant F, et al. Analysis of neuronal, glial, endothelial, axonal and apoptotic markers following moderate therapeutic hypothermia and anesthesia in the developing piglet brain. Brain Pathol 2008;18:10-20.
-
(2008)
Brain Pathol.
, vol.18
, pp. 10-20
-
-
Gressens, P.1
Dingley, J.2
Plaisant, F.3
-
17
-
-
45549110385
-
Global profiling of influence of intraischemic brain temperature on gene expression in rat brain
-
Kobayashi MS, Asai S, Ishikawa K, et al. Global profiling of influence of intraischemic brain temperature on gene expression in rat brain. Brain Res Rev 2008;58:171-191.
-
(2008)
Brain Res. Rev.
, vol.58
, pp. 171-191
-
-
Kobayashi, M.S.1
Asai, S.2
Ishikawa, K.3
-
18
-
-
34547759327
-
Guidelines for the management of severe traumatic brain injury
-
Brain Trauma Foundation
-
Brain Trauma Foundation. Guidelines for the management of severe traumatic brain injury. J Neurotrauma 2007;24: S26-S31.
-
(2007)
J. Neurotrauma
, vol.24
-
-
-
19
-
-
62649153414
-
Current and future role of therapeutic hypothermia
-
••, Most recent overall review on neuroprotective effects of hypothermia in all indications from cardiac arrest, HIE to traumatic brain injury or.
-
Marion D, Bullock R. Current and future role of therapeutic hypothermia. •• J Neurotrauma 2009;26:455-467. Most recent overall review on neuroprotective effects of hypothermia in all indications (from cardiac arrest, HIE to traumatic brain injury or...)
-
(2009)
J. Neurotrauma
, vol.26
, pp. 455-467
-
-
Marion, D.1
Bullock, R.2
-
20
-
-
0036314346
-
The role of hypothermia in the management of severe brain injury: A meta-analysis
-
Harris OA, Colford JM Jr, Good MC, et al. The role of hypothermia in the management of severe brain injury: a meta-analysis. Arch Neurol 2002;59:1077-1083.
-
(2002)
Arch. Neurol.
, vol.59
, pp. 1077-1083
-
-
Harris, O.A.1
Colford Jr., J.M.2
Good, M.C.3
-
21
-
-
0242425880
-
Hypothermia in the management of traumatic brain injury. A systematic review and meta-analysis
-
Henderson WR, Dhingra VK, Chittock DR, et al. Hypothermia in the management of traumatic brain injury. A systematic review and meta-analysis. Intensive Care Med 2003;29:1637-1644.
-
(2003)
Intensive Care Med.
, vol.29
, pp. 1637-1644
-
-
Henderson, W.R.1
Dhingra, V.K.2
Chittock, D.R.3
-
22
-
-
0037805276
-
Prolonged therapeutic hypothermia after traumatic brain injury in adults: A systematic review
-
McIntyre LA, Fergusson DA, Hebert PC, et al. Prolonged therapeutic hypothermia after traumatic brain injury in adults: a systematic review. JAMA 2003;289:2992-2999.
-
(2003)
JAMA
, vol.289
, pp. 2992-2999
-
-
McIntyre, L.A.1
Fergusson, D.A.2
Hebert, P.C.3
-
24
-
-
38549170583
-
Hypothermia treatment for traumatic brain •• injury: A systematic review and meta-analysis
-
This most recent meta-analysis proceeded with a cautious approach concerning influence of variability in between-groups comparability and conducted final metaanalyses based only on the eight trials n = 806 with comparable groups. These trials revealed a 20% reduction in mortality relative to conventional therapy and a 25% increased incidence of a good neurological outcome, but none of these effects was found to be statistically significant. In subgroup analyses, variations in cooling duration, ICP management strategy, and trial duration were found to have significant influences on risk of mortality
-
Peterson K, Carson S, Carney N. Hypothermia treatment for traumatic brain •• injury: a systematic review and meta-analysis. J Neurotrauma 2008;25:62-71. This most recent meta-analysis proceeded with a cautious approach (concerning influence of variability in between-groups comparability) and conducted final metaanalyses based only on the eight trials (n = 806) with comparable groups. These trials revealed a 20% reduction in mortality relative to conventional therapy and a 25% increased incidence of a good neurological outcome, but none of these effects was found to be statistically significant. In subgroup analyses, variations in cooling duration, ICP management strategy, and trial duration were found to have significant influences on risk of mortality.
-
(2008)
J. Neurotrauma
, vol.25
, pp. 62-71
-
-
Peterson, K.1
Carson, S.2
Carney, N.3
-
25
-
-
67649194940
-
Effect of 35°C hypothermia on • intracranial pressure and clinical outcome in patients with severe traumatic brain injury
-
Cooling patients to 35°C is well tolerated and the ICP reduction effects of 35°C hypothermia are similar to those of 33°C hypothermia
-
Tokutomi T, Miyagi T, Takeuchi Y, et al. Effect of 35°C hypothermia on • intracranial pressure and clinical outcome in patients with severe traumatic brain injury. J Trauma 2009;66:166-173. Cooling patients to 35°C is well tolerated and the ICP reduction effects of 35°C hypothermia are similar to those of 33°C hypothermia.
-
(2009)
J. Trauma.
, vol.66
, pp. 166-173
-
-
Tokutomi, T.1
Miyagi, T.2
Takeuchi, Y.3
-
26
-
-
55049131692
-
Modest cooling therapies (35°C to 37. 5°C) for traumatic brain injury (Review)
-
Saxena M, Andrews P J D, Cheng A. Modest cooling therapies (35°C to 37. 5°C) for traumatic brain injury (Review). Cochrane Database Syst Rev 2008;3: CD006811.
-
(2008)
Cochrane Database Syst. Rev.
, vol.3
-
-
Saxena, M.1
Andrews, P.J.D.2
Cheng, A.3
-
27
-
-
0035931948
-
Lack of effect of induction of hypothermia after acute brain injury
-
Clifton GL, Miller ER, Choi SC, et al. Lack of effect of induction of hypothermia after acute brain injury. N Engl J Med 2001;344:556-563.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 556-563
-
-
Clifton, G.L.1
Miller, E.R.2
Choi, S.C.3
-
28
-
-
0036130194
-
Hypothermia on admission in patients with severe brain injury
-
Clifton GL, Miller ER, Choi Sc, et al. Hypothermia on admission in patients with severe brain injury. J Neurotrauma 2002;19:293-301.
-
(2002)
J. Neurotrauma
, vol.19
, pp. 293-301
-
-
Clifton, G.L.1
Miller, E.R.2
Sc, C.3
-
29
-
-
62649153915
-
Multicenter trial of early hypothermia in •• severe brain injury
-
The North American Brain Injury Study: Hypothermia IIR NABIS:H IIR is a randomized clinical trial designed to enroll 240 patients with TBI, aged 16-45 years. As of December 2007, 74 patients have been randomized to phase II 33°C of the protocol. The hypothesis is that short cooling times and standardized ICU management to minimize hypotension should offer the greatest opportunity of detecting a treatment effect of therapeutic hypothermia after TBI
-
Clifton GL, Drever P, Valadka A, et al. Multicenter trial of early hypothermia in •• severe brain injury. J Neurotrauma 2009;26:393-397. The North American Brain Injury Study: Hypothermia IIR (NABIS:H IIR) is a randomized clinical trial designed to enroll 240 patients with TBI, aged 16-45 years. As of December 2007, 74 patients have been randomized to phase II (33°C) of the protocol. The hypothesis is that short cooling times and standardized ICU management to minimize hypotension should offer the greatest opportunity of detecting a treatment effect of therapeutic hypothermia after TBI.
-
(2009)
J. Neurotrauma
, vol.26
, pp. 393-397
-
-
Clifton, G.L.1
Drever, P.2
Valadka, A.3
-
31
-
-
38849092007
-
Prehospital induction of therapeutic hypothermia during CPR: A pilot study
-
Kamarainen A, Virkkunen I, Tenhunen J, et al. Prehospital induction of therapeutic hypothermia during CPR: a pilot study. Resuscitation 2008;76:360-363.
-
(2008)
Resuscitation
, vol.76
, pp. 360-363
-
-
Kamarainen, A.1
Virkkunen, I.2
Tenhunen, J.3
-
32
-
-
34250699452
-
Pilot randomized clinical trial of prehospital induction of mild hypothermia in out-of-hospital cardiac arrest patients with a rapid infusion of 4°C normal saline
-
Kim F, Olsufka M, Longstreth WT Jr, et al. Pilot randomized clinical trial of prehospital induction of mild hypothermia in out-of-hospital cardiac arrest patients with a rapid infusion of 4°C normal saline. Circulation 2007;115:3064-3070.
-
(2007)
Circulation
, vol.115
, pp. 3064-3070
-
-
Kim, F.1
Olsufka, M.2
Longstreth Jr., W.T.3
-
33
-
-
33745658445
-
Rapid infusion of cold saline (4 degress C) as adjunctive treatment of fever in patients with brain injury
-
Badjatia N, Bodock M, Guanci M, et al. Rapid infusion of cold saline (4 degress C) as adjunctive treatment of fever in patients with brain injury. Neurology 2006;66:1739-1741.
-
(2006)
Neurology
, vol.66
, pp. 1739-1741
-
-
Badjatia, N.1
Bodock, M.2
Guanci, M.3
-
34
-
-
23244464434
-
Pilot study of rapid infusion of 2L of 4°C normal saline for induction of mild hypothermia in hospitalized, comatose survivors of out-of-hospital cardiac arrest
-
Kim F, Olsufka M, Carlbom D, et al. Pilot study of rapid infusion of 2L of 4°C normal saline for induction of mild hypothermia in hospitalized, comatose survivors of out-of-hospital cardiac arrest. Circulation 2005;112:715-719.
-
(2005)
Circulation
, vol.112
, pp. 715-719
-
-
Kim, F.1
Olsufka, M.2
Carlbom, D.3
-
35
-
-
34848813786
-
Comparison of cooling methods to induce and maintain normoand hypothermia in intensive care unit patients. A prospective intervention study
-
Hoedemaekers CW, Ezzahti M, Gerritsen A, et al. Comparison of cooling methods to induce and maintain normoand hypothermia in intensive care unit patients. A prospective intervention study. Crit Care 2007;11: R91.
-
(2007)
Crit. Care
, vol.11
-
-
Hoedemaekers, C.W.1
Ezzahti, M.2
Gerritsen, A.3
-
36
-
-
67650790545
-
Discrete cerebral hypothermia in the management of traumatic brain injury: A randomized controlled trial
-
Harris O, Muh C, Surles M, et al. Discrete cerebral hypothermia in the management of traumatic brain injury: a randomized controlled trial. J Neurosurg 2009;110:1256-1264.
-
(2009)
J. Neurosurg.
, vol.110
, pp. 1256-1264
-
-
Harris, O.1
Muh, C.2
Surles, M.3
-
37
-
-
4644307479
-
A novel approach for selective brain cooling: Implications for hypercapnia and seizure activity
-
Truebel H, Herman P, Kampmann C, et al. A novel approach for selective brain cooling: implications for hypercapnia and seizure activity. Intensive Care Med 2004;30:1829-1833.
-
(2004)
Intensive Care Med.
, vol.30
, pp. 1829-1833
-
-
Truebel, H.1
Herman, P.2
Kampmann, C.3
-
38
-
-
60749121261
-
Pharyngeal selective brain cooling improves neurofunctional and neurocognitive outcome after fluid percussion brain injury in rats
-
Doll H, Truebel H, Kipfmueller F, et al. Pharyngeal selective brain cooling improves neurofunctional and neurocognitive outcome after fluid percussion brain injury in rats. J Neurotrauma 2009;26:235-242.
-
(2009)
J. Neurotrauma
, vol.26
, pp. 235-242
-
-
Doll, H.1
Truebel, H.2
Kipfmueller, F.3
-
39
-
-
62649144659
-
Management of pitfalls for the successful clinical use of hypothermia treatment
-
Hayashi N. Management of pitfalls for the successful clinical use of hypothermia treatment. J Neurotrauma 2009;26:445-453.
-
(2009)
J. Neurotrauma
, vol.26
, pp. 445-453
-
-
Hayashi, N.1
-
40
-
-
38049028378
-
Practical pharmacologic aspects of therapeutic hypothermia after cardiac arrest
-
Arpino PA, Greer DM. Practical pharmacologic aspects of therapeutic hypothermia after cardiac arrest. Pharmacotherapy 2008;28:102-111.
-
(2008)
Pharmacotherapy
, vol.28
, pp. 102-111
-
-
Arpino, P.A.1
Greer, D.M.2
-
41
-
-
62649117345
-
Hypothermia following pediatric traumatic brain injury
-
Adelson D. Hypothermia following pediatric traumatic brain injury. J Neurotrauma 2009;26:429-436.
-
(2009)
J. Neurotrauma
, vol.26
, pp. 429-436
-
-
Adelson, D.1
-
42
-
-
44849089005
-
Hypothermia therapy after traumatic brain injury in children
-
DOI 10.1056/NEJMoa0706930
-
Hutchison J, Ward R, Lacroix J, et al. Hypothermia therapy after traumatic brain •• injury in children. N Engl J Med 2008;358:2447-2456. Multicenter trial, randomly assigning children with severe TBI either to hypothermia (32.5°C for 24 h) initiated within 8h after injury or to normothermia (37.0°C). Results revealed that hypothermia did not improve neurological outcome and may increase mortality. (Pubitemid 351793018)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.23
, pp. 2447-2456
-
-
Hutchison, J.S.1
Ward, R.E.2
Lacroix, J.3
Hebert, P.C.4
Barnes, M.A.5
Bohn, D.J.6
Dirks, P.B.7
Doucette, S.8
Fergusson, D.9
Gottesman, R.10
Joffe, A.R.11
Kirpalani, H.M.12
Meyer, P.G.13
Morris, K.P.14
Moher, D.15
Singh, R.N.16
Skippen, P.W.17
-
43
-
-
20144389933
-
Phase II clinical trial of moderate hypothermia after severe traumatic brain injury in children
-
Adelson PD, Raghe J, Kanev P, et al. Phase II clinical trial of moderate hypothermia after severe traumatic brain injury in children. Neurosurgery 2005;56:740-754.
-
(2005)
Neurosurgery
, vol.56
, pp. 740-754
-
-
Adelson, P.D.1
Raghe, J.2
Kanev, P.3
-
44
-
-
34548478595
-
Effects of therapeutic mild hypothermia on patients with severe traumatic brain injury after craniotomy
-
Qiu W, Zhang Y, Sheng H, et al. Effects of therapeutic mild hypothermia on patients with severe traumatic brain injury after craniotomy. J Crit Care 2007;22:229-236.
-
(2007)
J. Crit. Care
, vol.22
, pp. 229-236
-
-
Qiu, W.1
Zhang, Y.2
Sheng, H.3
-
45
-
-
62649166942
-
Posthypothermic rewarming considerations following traumatic brain injury
-
Povlishock JT, Wei EP. Posthypothermic rewarming considerations following traumatic brain injury. J Neurotrauma 2009;26:333-340.
-
(2009)
J. Neurotrauma
, vol.26
, pp. 333-340
-
-
Povlishock, J.T.1
Wei, E.P.2
-
46
-
-
67650315435
-
Hyperthermia and fever control in brain injury
-
Badjatia N. Hyperthermia and fever control in brain injury. Crit Care Med 2009;37(suppl): S250-S257.
-
(2009)
Crit. Care Med.
, vol.37
, Issue.SUPPL.
-
-
Badjatia, N.1
-
47
-
-
70349306274
-
Induced normothermia attenuates intracranial hypertension and reduces fever burden after severe traumatic brain injury
-
Puccio AM, Fischer MR, Jankowitz BT, et al. Induced normothermia attenuates intracranial hypertension and reduces fever burden after severe traumatic brain injury. Neurocrit Care 2009;11:82-87.
-
(2009)
Neurocrit Care
, vol.11
, pp. 82-87
-
-
Puccio, A.M.1
Fischer, M.R.2
Jankowitz, B.T.3
|