Small scale genetic alterations contribute to increased mutability at the X-linked Hprt locus in vivo in Blm hypomorphic mice

DNA Repair

Volumn 9, Issue 5, 2010, Pages 551-557

  Tereshchenko, Irina V ^a   Chen, Yanping ^a   McDaniel, Lisa D ^b   Schultz, Roger A ^b   Tischfield, Jay A ^a   Shao, Changshun ^a,c  

^a RUTGERS UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

BLM; Deletion; Hprt; Mutation

Indexed keywords

BLOOM SYNDROME HELICASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; DNA REPLICATION; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENE LOCUS; GENETIC DISORDER; HETEROZYGOSITY; IN VIVO STUDY; INVERTED REPEAT; MALE; MOLECULAR CLONING; MOLECULAR GENETICS; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; SOMATIC CELL;

ANIMALS; BASE SEQUENCE; BLOOM SYNDROME; DISEASE SUSCEPTIBILITY; DNA MUTATIONAL ANALYSIS; FEMALE; FIBROBLASTS; GENES, X-LINKED; GENETIC LOCI; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INVERTED REPEAT SEQUENCES; MALE; MICE; MOLECULAR SEQUENCE DATA; MUTATION; RECQ HELICASES; SEQUENCE DELETION; SEQUENCE HOMOLOGY, NUCLEIC ACID; T-LYMPHOCYTES;

MUS;

EID: 77952108629     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2010.02.005     Document Type: Article

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