Common polymorphisms of calpain-10 and the risk of Type 2 Diabetes in a Tunisian Arab population: A case-control study

BMC Medical Genetics

Volumn 11, Issue 1, 2010, Pages

  Ezzidi, Intissar ^a   Turki, Amira ^a   Messaoudi, Safia ^a   Chaieb, Molka ^c   Kacem, Maha ^d   Al Khateeb, Ghada M ^e   Mahjoub, Touhami ^a   Almawi, Wassim Y ^e   Mtiraoui, Nabil ^a,b  

^a UNIVERSITY OF MONASTIR   (Tunisia)

^b UNIVERSITY OF MONASTIR   (Tunisia)

^c FARHAT HACHED HOSPITAL   (Tunisia)

^d FATTOUMA BOURGUIBA UNIVERSITY HOSPITAL   (Tunisia)

^e ARABIAN GULF UNIVERSITY   (Bahrain)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN 10; ORAL ANTIDIABETIC AGENT; CALPAIN;

ADULT; AGED; ARAB; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HIGH RISK POPULATION; HISPANIC; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POPULATION BASED CASE CONTROL STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; TUNISIA; CASE CONTROL STUDY; GENETICS; MIDDLE AGED; RISK;

ADULT; AGED; AGED, 80 AND OVER; ARABS; CALPAIN; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK; TUNISIA;

EID: 77952108048     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-11-75     Document Type: Article

References (28)

1. Ghosh S, Watanabe RM, Hauser ER, Valle T, Magnuson VL, Erdos MR, Langefeld CD, Balow J, Ally DS, Kohtamaki K, et al. Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc Natl Acad Sci USA 1999, 96(5):2198-2203. 10.1073/pnas.96.5.2198, 26760, 10051618.
2. Wiltshire S, Hattersley AT, Hitman GA, Walker M, Levy JC, Sampson M, O'Rahilly S, Frayling TM, Bell JI, Lathrop GM, et al. A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am J Hum Genet 2001, 69(3):553-569. 10.1086/323249, 1235485, 11484155.
3. Cox NJ, Hayes MG, Roe CA, Tsuchiya T, Bell GI. Linkage of calpain 10 to type 2 diabetes: the biological rationale. Diabetes 2004, 53(Suppl 1):S19-25. 10.2337/diabetes.53.2007.S19, 14749261.
4. Weedon MN, Schwarz PE, Horikawa Y, Iwasaki N, Illig T, Holle R, Rathmann W, Selisko T, Schulze J, Owen KR, et al. Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility. Am J Hum Genet 2003, 73(5):1208-1212. 10.1086/379285, 1180500, 14574648.
5. Dear TN, Boehm T. Identification and characterization of two novel calpain large subunit genes. Gene 2001, 274(1-2):245-252. 10.1016/S0378-1119(01)00599-6, 11675017.
6. Carlsson E, Poulsen P, Storgaard H, Almgren P, Ling C, Jensen CB, Madsbad S, Groop L, Vaag A, Ridderstrale M. Genetic and nongenetic regulation of CAPN10 mRNA expression in skeletal muscle. Diabetes 2005, 54(10):3015-3020. 10.2337/diabetes.54.10.3015, 16186407.
7. Pihlajamaki J, Salmenniemi U, Vanttinen M, Ruotsalainen E, Kuusisto J, Vauhkonen I, Kainulainen S, Ng MC, Cox NJ, Bell GI, et al. Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes. Diabetologia 2006, 49(7):1560-1566. 10.1007/s00125-006-0270-z, 16752174.
8. Fullerton SM, Bartoszewicz A, Ybazeta G, Horikawa Y, Bell GI, Kidd KK, Cox NJ, Hudson RR, Di Rienzo A. Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus. Am J Hum Genet 2002, 70(5):1096-1106. 10.1086/339930, 447588, 11891618.
9. Tsuchiya T, Schwarz PE, Bosque-Plata LD, Geoffrey Hayes M, Dina C, Froguel P, Wayne Towers G, Fischer S, Temelkova-Kurktschiev T, Rietzsch H, et al. Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses. Mol Genet Metab 2006, 89(1-2):174-184. 10.1016/j.ymgme.2006.05.013, 16837224.
10. Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, et al. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 2000, 26(2):163-175. 10.1038/79876, 11017071.
11. del Bosque-Plata L, Aguilar-Salinas CA, Tusie-Luna MT, Ramirez-Jimenez S, Rodriguez-Torres M, Auron-Gomez M, Ramirez E, Velasco-Perez ML, Ramirez-Silva A, Gomez-Perez F, et al. Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population. Mol Genet Metab 2004, 81(2):122-126. 10.1016/j.ymgme.2003.10.005, 14741193.
12. Chen SF, Lu XF, Yan WL, Huang JF, Gu DF. Variations in the calpain-10 gene are associated with the risk of type 2 diabetes and hypertension in northern Han Chinese population. Chin Med J (Engl) 2007, 120(24):2218-2223.
13. Iwasaki N, Horikawa Y, Tsuchiya T, Kitamura Y, Nakamura T, Tanizawa Y, Oka Y, Hara K, Kadowaki T, Awata T, et al. Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population. J Hum Genet 2005, 50(2):92-98. 10.1007/s10038-004-0225-5, 15696376.
14. Garant MJ, Kao WH, Brancati F, Coresh J, Rami TM, Hanis CL, Boerwinkle E, Shuldiner AR. SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study. Diabetes 2002, 51(1):231-237. 10.2337/diabetes.51.1.231, 11756346.
15. Rasmussen SK, Urhammer SA, Berglund L, Jensen JN, Hansen L, Echwald SM, Borch-Johnsen K, Horikawa Y, Mashima H, Lithell H, et al. Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians. Diabetes 2002, 51(12):3561-3567. 10.2337/diabetes.51.12.3561, 12453914.
16. Tsai HJ, Sun G, Weeks DE, Kaushal R, Wolujewicz M, McGarvey ST, Tufa J, Viali S, Deka R. Type 2 diabetes and three calpain-10 gene polymorphisms in Samoans: no evidence of association. Am J Hum Genet 2001, 69(6):1236-1244. 10.1086/324646, 1235535, 11704924.
17. Elbein SC, Chu W, Ren Q, Hemphill C, Schay J, Cox NJ, Hanis CL, Hasstedt SJ. Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians. J Clin Endocrinol Metab 2002, 87(2):650-654. 10.1210/jc.87.2.650, 11836299.
18. Ezzidi I, Mtiraoui N, Cauchi S, Vaillant E, Dechaume A, Chaieb M, Kacem M, Almawi WY, Froguel P, Mahjoub T, Vaxillaire M. Contribution of type 2 diabetes associated loci in the Arabic population from Tunisia: a case-control study. BMC Med Genet 2009, 10:33. 10.1186/1471-2350-10-33, 2678106, 19368707.
19. Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Rao PV, Bennett AJ, et al. Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom. Am J Hum Genet 2001, 69(3):544-552. 10.1086/323315, 1235484, 11481585.
20. Horikawa Y, Oda N, Yu L, Imamura S, Fujiwara K, Makino M, Seino Y, Itoh M, Takeda J. Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese. J Clin Endocrinol Metab 2003, 88(1):244-247. 10.1210/jc.2002-020847, 12519860.
21. Abecasis GR, Cookson WO, Cardon LR. Pedigree tests of transmission disequilibrium. Eur J Hum Genet 2000, 8(7):545-551. 10.1038/sj.ejhg.5200494, 10909856.
22. Hajjej A, Kâabi H, Sellami MH, Dridi A, Jeridi A, El borgi W, Cherif G, Elgaâïed A, Almawi WY, Boukef K, Hmida S. The contribution of HLA class I and II alleles and haplotypes to the investigation of the evolutionary history of Tunisians. Tissue Antigens 2006, 68(2):153-162. 10.1111/j.1399-0039.2006.00622.x, 16866885.
23. Saez ME, Gonzalez-Sanchez JL, Ramirez-Lorca R, Martinez-Larrad MT, Zabena C, Gonzalez A, Moron FJ, Ruiz A, Serrano-Rios M. The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population. PLoS One 2008, 3(8):e2953. 10.1371/journal.pone.0002953, 2495037, 18698425.
24. Ouederni TB, Sanchez-Corona J, Skhiri HA, Maiz HB, Abid HK, Benammar-Elgaaied A. [Study of association of the SNP19 polymorphism of calpain 10 gene with type 2 diabetes in ethnic sub-groups of the Tunisian population: gene-environment interaction]. Ann Biol Clin (Paris) 2009, 67(2):171-176.
25. Kifagi C, Makni K, Mnif F, Boudawara M, Hamza N, Rekik N, Abid M, Rebai A, Granier C, Jarraya F, et al. Association of calpain-10 polymorphisms with type 2 diabetes in the Tunisian population. Diabetes Metab 2008, 34(3):273-278. 10.1016/j.diabet.2008.01.007, 18487065.
26. Song Y, Niu T, Manson JE, Kwiatkowski DJ, Liu S. Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative assessment of population and family-based association studies. Am J Hum Genet 2004, 74(2):208-222. 10.1086/381400, 1181919, 14730479.
27. Kang ES, Kim HJ, Nam M, Nam CM, Ahn CW, Cha BS, Lee HC. A novel 111/121 diplotype in the Calpain-10 gene is associated with type 2 diabetes. J Hum Genet 2006, 51(7):629-633. 10.1007/s10038-006-0410-9, 16721485.
28. Song Y, You N, Hsu YH, Sul J, Wang L, Tinker L, Eaton CB, Liu S. Common genetic variation in calpain-10 gene (CAPN10) and diabetes risk in a multi-ethnic cohort of American postmenopausal women. Hum Mol Genet 2007, 16(23):2960-2971. 10.1093/hmg/ddm256, 17855447.