Genetic variations in calpain-10 gene are not a major factor in the occurrence of type 2 diabetes in Japanese

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 1, 2003, Pages 244-247

  Horikawa, Yukio ^a   Oda, Naohisa ^b   Yu, Li ^a,c   Imamura, Shigeo ^b   Fujiwara, Kentaro ^b   Makino, Masaki ^b   Seino, Yutaka ^c   Itoh, Mitsuyasu ^b   Takeda, Jun ^a  

^a GUNMA UNIVERSITY   (Japan)

^b FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; CALPAIN 10; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ETHNIC GROUP; EXON; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC RISK; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; STATISTICAL SIGNIFICANCE;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CALPAIN; DIABETES MELLITUS, TYPE 2; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GLUCOSE CLAMP TECHNIQUE; HAPLOTYPES; HUMANS; JAPAN; MALE; MEXICAN AMERICANS; MIDDLE AGED; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); VARIATION (GENETICS);

EID: 0037243596     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-020847     Document Type: Article

References (15)

1. Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PEH, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI 2000 Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 26:163-175
2. Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Subba Rao PV, Bennett AJ, Jones EC, Menzel S, Prestwich P, Simecek N, Wishart M, Dhillon R, Fletcher C, Millward A, Demaine A, Wilkin T, Horikawa Y, Cox NJ, Bell GI, Ellard S, McCarthy MI, Hattersley AT 2001 Association studies of the calpain-10 gene with type 2 diabetes mellitus in the United Kingdom. Am J Hum Genet 69:544-552
3. Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, Shen GQ, Mott D, Knowler WC, Cox NJ, Horikawa Y, Oda N, Bell GI, Bogardus C 2000 A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest 106:R69-R73
4. Elbein SC, Chu W, Ren Q, Hemphill C, Schay J, Cox NJ, Hanis CL, Hasstedt SJ 2002 Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians. J Clin Endocrinol Metab 87:650-654
5. Ehrmann DA, Schwarz PEH, Hara M, Tang Xu, Horikawa Y, Imperial J, Bell GI, Cox, NJ 2002 Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab 87:1669-1673
6. Lynn S, Evans JC, White C, Frayling TM, Hattersley AT, Tumbull DM, Horikawa Y, Cox NJ, Bell GI, Walker M 2002 Variation in the calpain-10 gene affects blood glucose levels in the British population. Diabetes 51:247-250
7. Kosaka K, Hagure R, Kuzuya T 1977 Insulin responses in equivocal and definite diabetes, with special reference to subjects who had mild glucose tolerance but later developed definite diabetes. Diabetes 26:944-952
8. Kuzuya T, Nakagawa S, Satoh, J, Kanazawa Y, Iwamoto Y, Kobayashi M, Nanjo K, Sasaki A, Seino Y, Ito C, Shima K, Nonaka K, Kadowaki T 2002 Report of the committee of the Japan Diabetes Society on the classification and diagnostic criteria of diabetes rnellitus. Diabetes Res Clin Pract 55:65-85
9. DeFronzo RA, Iordan DT, Reubin A 1979 Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223
10. Tsai HJ, Sun G, Weeks DE, Kaushal R, Wolujewicz M, McGarvey ST, Tufa J, Viali S, Deka R 2001 Type 2 diabetes and three calpain-10 gene polymorphisms in Samoans: no evidence of association. Am J Hum Genet 69:1236-1244
11. Saido TC, Sorimachi H, Suzuki K 1994 Calpain: new perspectives in molecular diversity and physiological-pathological involvement. FASEB J 8:814-822
12. Reaven GM, Hollenbeck C, Jeng CY, Wu MS, Chen Y-DI 1988 Measurement of plasma glucose, fatty acid, lactate, and insulin for 24 h in patients with NIDDM. Diabetes 37:1020-1024
13. Roden M, Price TB, Perseghin G, Petersen KF, Rothman DL, Cline GW, Shulman GI 1996 Mechanism of free fatty acid-induced insulin resistance in human. J Clin Invest 97:2859-2865
14. Chen YD, Golay A, Swislocki AL, Reaven GM 1987 Resistance to insulin suppression of plasma free fatty acid concentrations and insulin stimulation of glucose uptake in non-insulin dependent diabetes mellitus. J Clin Endocrinol Metab 64:17-21
15. Cox NJ, Frigge M, Nicolae DL, Concannon P, Hanis CL, Bell GI, Kong A 1999 Loci on chromosome 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans. Nat Genet 21:213-215