메뉴 건너뛰기




Volumn 1333, Issue , 2010, Pages 1-8

Ginsenoside Rg1 promotes glutamate release via a calcium/calmodulin-dependent protein kinase II-dependent signaling pathway

Author keywords

CaMKII; Fluorescent imaging system; Ginsenoside Rg1; Synapsin I

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; GINSENOSIDE RG 1; GLUTAMIC ACID; SERINE; SYNAPSIN I;

EID: 77952102126     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.03.096     Document Type: Article
Times cited : (27)

References (36)
  • 1
    • 0344549853 scopus 로고    scopus 로고
    • Ginseng pharmacology: multiple constituents and multiple actions
    • Attele A.S., Wu J.A., and Yuan C.S. Ginseng pharmacology: multiple constituents and multiple actions. Biochem. Pharmacol. 58 (1999) 1685-1693
    • (1999) Biochem. Pharmacol. , vol.58 , pp. 1685-1693
    • Attele, A.S.1    Wu, J.A.2    Yuan, C.S.3
  • 2
    • 0027476024 scopus 로고
    • A synaptic model of memory: long-term potentiation in the hippocampus
    • Bliss T.V., and Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361 (1993) 31-39
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 4
    • 0038504088 scopus 로고    scopus 로고
    • Ganglioside/calmodulin kinase II signal inducing cdc42-mediated neuronal actin reorganization
    • Chen N., Furuya S., Doi H., Hashimoto Y., Kudo Y., and Higashi H. Ganglioside/calmodulin kinase II signal inducing cdc42-mediated neuronal actin reorganization. Neuroscience 120 (2003) 163-176
    • (2003) Neuroscience , vol.120 , pp. 163-176
    • Chen, N.1    Furuya, S.2    Doi, H.3    Hashimoto, Y.4    Kudo, Y.5    Higashi, H.6
  • 5
    • 13444293396 scopus 로고    scopus 로고
    • Anti-amnestic and anti-aging effects of ginsenoside Rb1 and Rg1 and its mechanism of action
    • Cheng Y., Shen L.H., and Zhang J.T. Anti-amnestic and anti-aging effects of ginsenoside Rb1 and Rg1 and its mechanism of action. Acta Pharmacol. Sin. 26 (2005) 143-149
    • (2005) Acta Pharmacol. Sin. , vol.26 , pp. 143-149
    • Cheng, Y.1    Shen, L.H.2    Zhang, J.T.3
  • 6
    • 0042347897 scopus 로고    scopus 로고
    • Selective regulation of neurite extension and synapse formation by the b but not the a isoform of CaMKII
    • Fink C.C., Bayer K.-U., and Myers J.W. Selective regulation of neurite extension and synapse formation by the b but not the a isoform of CaMKII. Neuron 39 (2003) 283-297
    • (2003) Neuron , vol.39 , pp. 283-297
    • Fink, C.C.1    Bayer, K.-U.2    Myers, J.W.3
  • 8
    • 0033213603 scopus 로고    scopus 로고
    • A phospho-switch controls the dynamic association of synapsins with synaptic vesicles
    • Hosaka M., Hammer R.E., and Südhof T.C. A phospho-switch controls the dynamic association of synapsins with synaptic vesicles. Neuron 24 (1999) 377-387
    • (1999) Neuron , vol.24 , pp. 377-387
    • Hosaka, M.1    Hammer, R.E.2    Südhof, T.C.3
  • 9
    • 51349151189 scopus 로고    scopus 로고
    • Ginsenoside Rg1 activated CaMKIIα mediated extracellular signal-regulated kinase/mitogen activated protein kinase signaling pathway
    • Hu J.F., Xue W., Ning N., Yuan Y.H., Zhang J.T., and Chen N.H. Ginsenoside Rg1 activated CaMKIIα mediated extracellular signal-regulated kinase/mitogen activated protein kinase signaling pathway. Acta Pharmacol. Sin. 29 (2008) 1119-1126
    • (2008) Acta Pharmacol. Sin. , vol.29 , pp. 1119-1126
    • Hu, J.F.1    Xue, W.2    Ning, N.3    Yuan, Y.H.4    Zhang, J.T.5    Chen, N.H.6
  • 11
    • 0031596324 scopus 로고    scopus 로고
    • Ginsenosides Rg1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration
    • Kim Y.C., Kim S.R., Markelonis G.J., and Oh T.H. Ginsenosides Rg1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration. J. Neurosci. Res. 53 (1998) 426-432
    • (1998) J. Neurosci. Res. , vol.53 , pp. 426-432
    • Kim, Y.C.1    Kim, S.R.2    Markelonis, G.J.3    Oh, T.H.4
  • 12
    • 0027957753 scopus 로고
    • Interactions of ginsenosides with ligand-bindings of GABA(A) and GABA(B) receptors
    • Kimura T., Saunders P.A., Kim H.S., Rheu H.M., Oh K.W., and Ho I.K. Interactions of ginsenosides with ligand-bindings of GABA(A) and GABA(B) receptors. Gen. Pharmacol. 25 (1994) 193-199
    • (1994) Gen. Pharmacol. , vol.25 , pp. 193-199
    • Kimura, T.1    Saunders, P.A.2    Kim, H.S.3    Rheu, H.M.4    Oh, K.W.5    Ho, I.K.6
  • 13
    • 0027485836 scopus 로고
    • NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms
    • Malenka R.C., and Nicoll R.A. NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms. Trends Neurosci. 16 (1993) 521-527
    • (1993) Trends Neurosci. , vol.16 , pp. 521-527
    • Malenka, R.C.1    Nicoll, R.A.2
  • 15
    • 77952110682 scopus 로고    scopus 로고
    • CaMKIIalpha were investigated using peptide substrates modeled on the amino acid sequence encompassing Ser-9 of synapsin I
    • Musazzi L., Perez J., Hunt S.P., Racagni G., and Popoli M. CaMKIIalpha were investigated using peptide substrates modeled on the amino acid sequence encompassing Ser-9 of synapsin I. J. Biol. Chem. 273 (1998) 3166-3172
    • (1998) J. Biol. Chem. , vol.273 , pp. 3166-3172
    • Musazzi, L.1    Perez, J.2    Hunt, S.P.3    Racagni, G.4    Popoli, M.5
  • 16
    • 0002721949 scopus 로고    scopus 로고
    • Ginseng: recent advances and trends
    • Nah S.Y. Ginseng: recent advances and trends. Korean J. Ginseng Sci. 21 (1997) 1-12
    • (1997) Korean J. Ginseng Sci. , vol.21 , pp. 1-12
    • Nah, S.Y.1
  • 17
    • 0030299803 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II phosphorylation of the pre-synaptic protein synapsin I is persistently increased during long-term potentiation
    • 2+/calmodulin-dependent protein kinase II phosphorylation of the pre-synaptic protein synapsin I is persistently increased during long-term potentiation. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 15451-15456
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 15451-15456
    • Nayak, A.S.1    Moore, C.I.2    Browning, M.D.3
  • 19
    • 1842610004 scopus 로고    scopus 로고
    • Pre-synaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons
    • Ninan I., and Arancio O. Pre-synaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons. Neuron 42 (2004) 129-141
    • (2004) Neuron , vol.42 , pp. 129-141
    • Ninan, I.1    Arancio, O.2
  • 20
    • 0037047419 scopus 로고    scopus 로고
    • Basic fibroblast growth factor evokes a rapid glutamate release through activation of the MAPK pathway in cultured cortical neurons
    • Numakawa T., Yokomaku D., Kiyosue K., Adachi N., Matsumoto T., Numakawa Y., Taguchi T., Hatanaka H., and Yamada M. Basic fibroblast growth factor evokes a rapid glutamate release through activation of the MAPK pathway in cultured cortical neurons. J. Biol. Chem. 277 (2002) 28861-28869
    • (2002) J. Biol. Chem. , vol.277 , pp. 28861-28869
    • Numakawa, T.1    Yokomaku, D.2    Kiyosue, K.3    Adachi, N.4    Matsumoto, T.5    Numakawa, Y.6    Taguchi, T.7    Hatanaka, H.8    Yamada, M.9
  • 21
    • 58649111216 scopus 로고    scopus 로고
    • Ginsenoside Rg1 restores the impairment of learning induced by chronic morphine administration in rats
    • Qi D., Zhu Y., Wen L., Liu Q., and Qiao H. Ginsenoside Rg1 restores the impairment of learning induced by chronic morphine administration in rats. J. Psychopharmacol. 23 (2009) 74-83
    • (2009) J. Psychopharmacol. , vol.23 , pp. 74-83
    • Qi, D.1    Zhu, Y.2    Wen, L.3    Liu, Q.4    Qiao, H.5
  • 23
    • 4344622460 scopus 로고    scopus 로고
    • Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate
    • Radad K., Gille G., Moldzio R., Saito H., and Rausch W.D. Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate. Brain Res. 1021 (2004) 41-53
    • (2004) Brain Res. , vol.1021 , pp. 41-53
    • Radad, K.1    Gille, G.2    Moldzio, R.3    Saito, H.4    Rausch, W.D.5
  • 24
    • 0032561201 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II
    • 2+/calmodulin-dependent protein kinase II. J. Biol. Chem. 273 (1998) 28424-28429
    • (1998) J. Biol. Chem. , vol.273 , pp. 28424-28429
    • Rich, R.C.1    Schulman, H.2
  • 25
    • 0034868729 scopus 로고    scopus 로고
    • Neurotrophic and neuroprotective actions of ginsenosides Rb(1) and Rg(1)
    • Rudakewich M., Ba F., and Benishin C.G. Neurotrophic and neuroprotective actions of ginsenosides Rb(1) and Rg(1). Planta Med. 67 (2001) 533-537
    • (2001) Planta Med. , vol.67 , pp. 533-537
    • Rudakewich, M.1    Ba, F.2    Benishin, C.G.3
  • 26
    • 0029781368 scopus 로고    scopus 로고
    • Synaptic vesicle recycling in synapsin I knock-out mice
    • Ryan T.A., Li L., Chin L.S., Greengard P., and Smith S.J. Synaptic vesicle recycling in synapsin I knock-out mice. J. Cell Biol. 134 (1996) 1219-1227
    • (1996) J. Cell Biol. , vol.134 , pp. 1219-1227
    • Ryan, T.A.1    Li, L.2    Chin, L.S.3    Greengard, P.4    Smith, S.J.5
  • 27
    • 34249072490 scopus 로고    scopus 로고
    • NMDA receptor and iNOS are involved in the effects of ginsenoside Rg1 on hippocampal neurogenesis in ischemic gerbils
    • Shen L., and Zhang J. NMDA receptor and iNOS are involved in the effects of ginsenoside Rg1 on hippocampal neurogenesis in ischemic gerbils. Neurol. Res. 29 (2007) 270-273
    • (2007) Neurol. Res. , vol.29 , pp. 270-273
    • Shen, L.1    Zhang, J.2
  • 28
    • 0013686246 scopus 로고
    • Translocation of synapsin I in response to depolarization of isolated nerve terminals
    • Sihra T.S., Wang J.K., Gorelick F.S., and Greengard P. Translocation of synapsin I in response to depolarization of isolated nerve terminals. Proc. Natl. Acad. Sci. U. S. A. 86 (1989) 8108-8112
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 8108-8112
    • Sihra, T.S.1    Wang, J.K.2    Gorelick, F.S.3    Greengard, P.4
  • 29
    • 0027050487 scopus 로고
    • Synapsin I partially dissociates from synaptic vesicles during exocytosis induced by electrical stimulation
    • Torri T.F., Bossi M., Fesce R., Greengard P., and Valtorta F. Synapsin I partially dissociates from synaptic vesicles during exocytosis induced by electrical stimulation. Neuron 9 (1992) 1143-1153
    • (1992) Neuron , vol.9 , pp. 1143-1153
    • Torri, T.F.1    Bossi, M.2    Fesce, R.3    Greengard, P.4    Valtorta, F.5
  • 30
    • 0034501276 scopus 로고    scopus 로고
    • Herbal medicine: from the past to the future
    • Tyler V.E. Herbal medicine: from the past to the future. Public Health Nutr. 3 (2000) 447-452
    • (2000) Public Health Nutr. , vol.3 , pp. 447-452
    • Tyler, V.E.1
  • 31
    • 58149161253 scopus 로고    scopus 로고
    • Regulation of synaptic transmission by pre-synaptic CaMKII and BK channels
    • Wang Z.W. Regulation of synaptic transmission by pre-synaptic CaMKII and BK channels. Mol. Neurobiol. 38 (2008) 153-166
    • (2008) Mol. Neurobiol. , vol.38 , pp. 153-166
    • Wang, Z.W.1
  • 32
    • 0004641064 scopus 로고    scopus 로고
    • Effects of ginsenoside Rg1 on learning and memory impairment induced by β-amyloid peptide (25-35) and its mechanism of action
    • Wang X.Y., Chen J., and Zhang J.T. Effects of ginsenoside Rg1 on learning and memory impairment induced by β-amyloid peptide (25-35) and its mechanism of action. Acta Pharmacol. Sin. 36 (2001) 1-4
    • (2001) Acta Pharmacol. Sin. , vol.36 , pp. 1-4
    • Wang, X.Y.1    Chen, J.2    Zhang, J.T.3
  • 33
    • 59049094805 scopus 로고    scopus 로고
    • Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins
    • Wang J., Xu H.M., Yang H.D., Du X.X., Jiang H., and Xie J.X. Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins. Neurochem. Int. 54 (2009) 43-48
    • (2009) Neurochem. Int. , vol.54 , pp. 43-48
    • Wang, J.1    Xu, H.M.2    Yang, H.D.3    Du, X.X.4    Jiang, H.5    Xie, J.X.6
  • 34
    • 33746701913 scopus 로고    scopus 로고
    • Ginsenoside Rb1 promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway
    • Xue J.F., Liu Z.J., Hu J.F., Chen H., Zhang J.T., and Chen N.H. Ginsenoside Rb1 promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway. Brain Res. 1106 (2006) 91-98
    • (2006) Brain Res. , vol.1106 , pp. 91-98
    • Xue, J.F.1    Liu, Z.J.2    Hu, J.F.3    Chen, H.4    Zhang, J.T.5    Chen, N.H.6
  • 35
    • 25644432658 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II-discovery, progress in a quarter of a century, and perspective: implication for learning and memory
    • 2+/calmodulin-dependent protein kinase II-discovery, progress in a quarter of a century, and perspective: implication for learning and memory. Biol. Pharm. Bull. 28 (2005) 1342-1354
    • (2005) Biol. Pharm. Bull. , vol.28 , pp. 1342-1354
    • Yamauchi, T.1
  • 36
    • 0025518656 scopus 로고
    • Preliminary study on antiamnestic mechanism of ginsenoside Rg1 and Rb1
    • Zhang J.T., Qu Z.W., Liu Y., and Deng H.L. Preliminary study on antiamnestic mechanism of ginsenoside Rg1 and Rb1. Chin. Med. J. (Engl). 103 (1990) 932-938
    • (1990) Chin. Med. J. (Engl). , vol.103 , pp. 932-938
    • Zhang, J.T.1    Qu, Z.W.2    Liu, Y.3    Deng, H.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.