메뉴 건너뛰기




Volumn 110, Issue 2, 2010, Pages 428-437

Rottlerin inhibits migration of follicular thyroid carcinoma cells by PKCδ-independent destabilization of the focal adhesion complex

Author keywords

Focal adhesion complex; Migration; Protein kinase C ; Rac 1; Rho; Rottlerin

Indexed keywords

ACTIN; BETA1 INTEGRIN; CASPASE 3; FOCAL ADHESION KINASE; GUANOSINE TRIPHOSPHATASE; PAXILLIN; PROTEIN KINASE C DELTA; RAC1 PROTEIN; RHO FACTOR; ROTTLERIN; SMALL INTERFERING RNA; STAUROSPORINE;

EID: 77952082477     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22555     Document Type: Article
Times cited : (14)

References (29)
  • 1
    • 42349106119 scopus 로고    scopus 로고
    • Down-regulation of caspase-2 by rottlerin via protein kinase C-delta-independent pathway
    • DOI 10.1158/0008-5472.CAN-07-6244
    • Basu A, Adkins B, Basu C. 2008. Down-regulation of caspase-2 by rottlerin via protein kinase C-delta-independent pathway. Cancer Res 68:2795-2802. (Pubitemid 351556278)
    • (2008) Cancer Research , vol.68 , Issue.8 , pp. 2795-2802
    • Basu, A.1    Adkins, B.2    Basu, C.3
  • 4
    • 2342472716 scopus 로고    scopus 로고
    • Focal adhesion and actin dynamics: A place where kinases and proteases meet to promote invasion
    • Carragher NO, Frame MC. 2004. Focal adhesion and actin dynamics: A place where kinases and proteases meet to promote invasion. Trends Cell Biol 14:241-249.
    • (2004) Trends Cell Biol , vol.14 , pp. 241-249
    • Carragher, N.O.1    Frame, M.C.2
  • 5
    • 33745608468 scopus 로고    scopus 로고
    • Effects of PPARgamma agonists on cell survival and focal adhesions in a Chinese thyroid carcinoma cell line
    • DOI 10.1002/jcb.20839
    • Chen Y, Wang SM, Wu JC, Huang SH. 2006. Effects of PPARgamma agonists on cell survival and focal adhesions in a Chinese thyroid carcinoma cell line. J Cell Biochem 98:1021-1035. (Pubitemid 43993414)
    • (2006) Journal of Cellular Biochemistry , vol.98 , Issue.4 , pp. 1021-1035
    • Chen, Y.1    Wang, S.-M.2    Wu, J.-C.3    Huang, S.-H.4
  • 6
    • 0021853097 scopus 로고
    • Factors influencing the survival of patients with follicular carcinoma of the thyroid gland
    • Crile G, Jr., Pontius KI, Hawk WA. 1985. Factors influencing the survival of patients with follicular carcinoma of the thyroid gland. Surg Gynecol Obstet 160:409-413. (Pubitemid 15057832)
    • (1985) Surgery Gynecology and Obstetrics , vol.160 , Issue.5 , pp. 409-413
    • Crile Jr., G.1    Pontius, K.I.2    Hawk, W.A.3
  • 7
    • 33646442046 scopus 로고    scopus 로고
    • Increasing incidence of thyroid cancer in the United States, 1973-2002
    • Davies L, Welch HG. 2006. Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA 295:2164-2167.
    • (2006) JAMA , vol.295 , pp. 2164-2167
    • Davies, L.1    Welch, H.G.2
  • 8
    • 0026673125 scopus 로고
    • Invasion by cultured human follicular thyroid cancer correlates with increased beta 1 integrins and production of proteases
    • Demeure MJ, Damsky CH, Elfman F, Goretzki PE, Wong MG, Clark OH. 1992. Invasion by cultured human follicular thyroid cancer correlates with increased beta 1 integrins and production of proteases. World J Surg 16: 770-776.
    • (1992) World J Surg , vol.16 , pp. 770-776
    • Demeure, M.J.1    Damsky, C.H.2    Elfman, F.3    Goretzki, P.E.4    Wong, M.G.5    Clark, O.H.6
  • 9
    • 32144443450 scopus 로고    scopus 로고
    • Ubiquitin-mediated proteasomal degradation of Rho proteins by the CNF1 toxin
    • DOI 10.1016/S0076-6879(06)06033-2, PII S0076687906060332, 33, Regulators and Effectors of Small GTPases: Rho Family
    • Doye A, Boyer L, Mettouchi A, Lemichez E. 2006. Ubiquitin-mediated proteasomal degradation of Rho proteins by the CNF1 toxin. Methods Enzymol 406:447-456. (Pubitemid 43207458)
    • (2006) Methods in Enzymology , vol.406 , pp. 447-456
    • Doye, A.1    Boyer, L.2    Mettouchi, A.3    Lemichez, E.4
  • 10
    • 0031434085 scopus 로고    scopus 로고
    • Elevation of protein kinase C in thyrocytes isolated from a Lewis rat model of autoimmune thyroiditis prevents assembly of immunodetectable connexin43 gap junctions and reduces intercellular communication
    • Green LM, Lazarus JP, Song X, Stagg RB, LaBue M, Hilliker S. 1997. Elevation of protein kinase C in thyrocytes isolated from a Lewis rat model of autoimmune thyroiditis prevents assembly of immunodetectable connexin43 gap junctions and reduces intercellular communication. Thyroid 7:913-921. (Pubitemid 28041669)
    • (1997) Thyroid , vol.7 , Issue.6 , pp. 913-921
    • Green, L.M.1    Lazarus, J.P.2    Song, X.3    Stagg, R.B.4    Labue, M.5    Hilliker, S.6
  • 11
    • 0031880853 scopus 로고    scopus 로고
    • Distribution of the cadherin-catenin complex in normal human thyroid epithelium and a thyroid carcinoma cell line
    • Huang SH, Wu JC, Chang KJ, Liaw KY, Wang SM. 1998. Distribution of the cadherin-catenin complex in normal human thyroid epithelium and a thyroid carcinoma cell line. J Cell Biochem 70:330-337.
    • (1998) J Cell Biochem , vol.70 , pp. 330-337
    • Huang, S.H.1    Wu, J.C.2    Chang, K.J.3    Liaw, K.Y.4    Wang, S.M.5
  • 13
    • 33645916718 scopus 로고    scopus 로고
    • Protein kinase Cdelta signaling downstreamof the EGF receptormediatesmigration and invasiveness of prostate cancer cells
    • Kharait S, Dhir R, Lauffenburger D, Wells A. 2006. Protein kinase Cdelta signaling downstreamof the EGF receptormediatesmigration and invasiveness of prostate cancer cells. Biochem Biophys Res Commun 343:848-856.
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 848-856
    • Kharait, S.1    Dhir, R.2    Lauffenburger, D.3    Wells, A.4
  • 14
    • 0036947279 scopus 로고    scopus 로고
    • Protein kinase Cdelta (PKCdelta): Activation mechanisms and functions
    • Kikkawa U, Matsuzaki H, Yamamoto T. 2002. Protein kinase C delta (PKC delta): Activation mechanisms and functions. J Biochem(Tokyo) 132:831-839. (Pubitemid 36090647)
    • (2002) Journal of Biochemistry , vol.132 , Issue.6 , pp. 831-839
    • Kikkawa, U.1    Matsuzaki, H.2    Yamamoto, T.3
  • 16
    • 33646503474 scopus 로고    scopus 로고
    • Activation of protein kinase C delta induces growth arrest in NPA thyroid cancer cells through extracellular signal-regulated kinase mitogen-activated protein kinase
    • Koike K, Fujii T, Nakamura AM, Yokoyama G, Yamana H, Kuwano M, Shirouzu K. 2006. Activation of protein kinase C delta induces growth arrest in NPA thyroid cancer cells through extracellular signal-regulated kinase mitogen-activated protein kinase. Thyroid 16:333-341.
    • (2006) Thyroid , vol.16 , pp. 333-341
    • Koike, K.1    Fujii, T.2    Nakamura, A.M.3    Yokoyama, G.4    Yamana, H.5    Kuwano, M.6    Shirouzu, K.7
  • 17
    • 0036070562 scopus 로고    scopus 로고
    • Proteasomal degradation of cytotoxic necrotizing factor 1-activated Rac
    • DOI 10.1128/IAI.70.8.4053-4058.2002
    • Lerm M, Pop M, Fritz G, Aktories K, Schmidt G. 2002. Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac. Infect Immun 70:4053-4058. (Pubitemid 34790912)
    • (2002) Infection and Immunity , vol.70 , Issue.8 , pp. 4053-4058
    • Lerm, M.1    Pop, M.2    Fritz, G.3    Aktories, K.4    Schmidt, G.5
  • 18
    • 33646591223 scopus 로고    scopus 로고
    • Macrophage activation increases the invasive properties of hepatoma cells by destabilization of the adherens junction
    • Lin CY, Lin CJ, Chen KH, Wu JC, Huang SH, Wang SM. 2006. Macrophage activation increases the invasive properties of hepatoma cells by destabilization of the adherens junction. FEBS Lett 580:3042-3050.
    • (2006) FEBS Lett , vol.580 , pp. 3042-3050
    • Lin, C.Y.1    Lin, C.J.2    Chen, K.H.3    Wu, J.C.4    Huang, S.H.5    Wang, S.M.6
  • 19
  • 22
    • 20444480169 scopus 로고    scopus 로고
    • Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome- Mediated degradation in vascular smooth muscle cells
    • DOI 10.1161/01.RES.0000170084.88780.ea
    • Rolli-Derkinderen M, Sauzeau V, Boyer L, Lemichez E, Baron C, Henrion D, Loirand G, Pacaud P. 2005. Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells. Circ Res 96:1152-1160. (Pubitemid 40827690)
    • (2005) Circulation Research , vol.96 , Issue.11 , pp. 1152-1160
    • Rolli-Derkinderen, M.1    Sauzeau, V.2    Boyer, L.3    Lemichez, E.4    Baron, C.5    Henrion, D.6    Loirand, G.7    Pacaud, P.8
  • 23
    • 0035475321 scopus 로고    scopus 로고
    • Paxillin: A focal adhesion-associated adaptor protein
    • Schaller MD. 2001. Paxillin: A focal adhesion-associated adaptor protein. Oncogene 20:6459-6472.
    • (2001) Oncogene , vol.20 , pp. 6459-6472
    • Schaller, M.D.1
  • 25
    • 0035851112 scopus 로고    scopus 로고
    • Rottlerin is a Mitochondrial Uncoupler that Decreases Cellular ATP Levels and Indirectly Blocks Protein Kinase Cdelta Tyrosine Phosphorylation
    • Soltoff SP. 2001. Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cdelta tyrosine phosphorylation. J Biol Chem 276:37986-37992. (Pubitemid 37384049)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.41 , pp. 37986-37992
    • Soltoff, S.P.1
  • 26
    • 34548511124 scopus 로고    scopus 로고
    • Rottlerin: An inappropriate and ineffective inhibitor of PKCdelta
    • Soltoff SP. 2007. Rottlerin: An inappropriate and ineffective inhibitor of PKCdelta. Trends Pharmacol Sci 28:453-458.
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 453-458
    • Soltoff, S.P.1
  • 27
    • 10944238407 scopus 로고    scopus 로고
    • Distinctive activation mechanisms and functions for protein kinase Cdelta
    • Steinberg SF. 2004. Distinctive activation mechanisms and functions for protein kinase Cdelta. Biochem J 384:449-459.
    • (2004) Biochem J , vol.384 , pp. 449-459
    • Steinberg, S.F.1
  • 29
    • 26944457329 scopus 로고    scopus 로고
    • Lovastatin suppresses invasiveness of anaplastic thyroid cancer cells by inhibiting Rho geranylgeranylation and RhoA/ROCK signaling
    • Zhong WB, Liang YC, Wang CY, Chang TC, Lee WS. 2005. Lovastatin suppresses invasiveness of anaplastic thyroid cancer cells by inhibiting Rho geranylgeranylation and RhoA/ROCK signaling. Endocr Relat Cancer 12:615-629.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 615-629
    • Zhong, W.B.1    Liang, Y.C.2    Wang, C.Y.3    Chang, T.C.4    Lee, W.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.