Optimization of a non-radioactive high-throughput assay for decarboxylase enzymes

Assay and Drug Development Technologies

Volumn 8, Issue 2, 2010, Pages 175-185

  Smithson, David C ^a,b   Shelat, Anang A ^b   Baldwin, Jeffrey ^c   Phillips, Margaret A ^c   Guy, R Kiplin ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; MALATE DEHYDROGENASE; ORNITHINE DECARBOXYLASE; PHOSPHOENOLPYRUVATE CARBOXYLASE;

ARTICLE; AUTOMATION; CONTROLLED STUDY; DECARBOXYLATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; HIGH THROUGHPUT SCREENING; HYDROPHOBICITY; NONHUMAN; PARASITOLOGY; PROCESS OPTIMIZATION; RECEIVER OPERATING CHARACTERISTIC; TRYPANOSOMA BRUCEI;

ANIMALS; BICARBONATES; CARBOXY-LYASES; DATA INTERPRETATION, STATISTICAL; DRUG EVALUATION, PRECLINICAL; ENZYME ASSAYS; ENZYME INHIBITORS; MALATE DEHYDROGENASE; ORNITHINE DECARBOXYLASE; PHOSPHOENOLPYRUVATE CARBOXYLASE; ROC CURVE; TRYPANOSOMA BRUCEI BRUCEI;

EID: 77952076850     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2009.0249     Document Type: Article

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