Establishment and characterization of a new drug surviving cell line Am1010, derived directly from muscle metastases of a human lung adenocarcinoma patient with multi-drug-resistance to cisplatin, taxol, and gefitinib

Acta Pharmacologica Sinica

Volumn 31, Issue 5, 2010, Pages 601-608

  Li, Hui Ling ^a   Xie, Si Ming ^b   Zhang, Liang ^c   Cai, Cheng Jie ^a   Wang, Wei ^a   Huang, Jun ^a   Wang, Dao Yuan ^a   Wen, Dan Ping ^a   Deng, Qiu Hua ^a   Zhong, Nan Shan ^a   He, Jian Xing ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

^c NATIONAL ENGINEERING RESEARCH CENTER FOR BEIJING BIOCHIP TECHNOLOGY   (China)

Author keywords

Am1010; Drug surviving cells; Focal and cell adhesion; Lung adenocarcinoma; Metastases; Multi drug resistance

Indexed keywords

CISPLATIN; GEFITINIB; PACLITAXEL;

ANIMAL EXPERIMENT; ARTICLE; BONE TUMOR; CANCER CELL CULTURE; CANCER GROWTH; CELL ADHESION; CELL STRAIN; CELL STRAIN AM 1010; CELL STRUCTURE; CHROMOSOME ANALYSIS; CHROMOSOME NUMBER; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; ELECTRON MICROSCOPY; FEMALE; FOCAL ADHESION; GENE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; IN VITRO STUDY; IN VIVO STUDY; LUNG ADENOCARCINOMA; LYMPH NODE; LYMPH NODE BIOPSY; MICROARRAY ANALYSIS; MOUSE; MULTIDRUG RESISTANCE; MUSCLE METASTASIS; NONHUMAN; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOCARCINOMA; ADULT; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMOSOMES; CISPLATIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION PROFILING; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; PACLITAXEL; QUINAZOLINES;

EID: 77952039045     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.41     Document Type: Article

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