메뉴 건너뛰기




Volumn 6, Issue 4, 2006, Pages 358-359

Downregulation of SOST/sclerostin by PTH: A novel mechanism of hormonal control of bone formation mediated by osteocytes

Author keywords

Osteoblast apoptosis; Osteocytes; PTH; Sost

Indexed keywords

AXIN; BONE MORPHOGENETIC PROTEIN; COLLAGEN TYPE 1; GLYCOPROTEIN; OSTEOCALCIN; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR 1; SCLEROSTIN; SMAD6 PROTEIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

EID: 33846255350     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (59)

References (13)
  • 1
    • 0002272879 scopus 로고    scopus 로고
    • Histomorphometric analysis of bone in primary hyperparathyroidism
    • Bilezikian JP, Marcus R, Levine MA (eds) Academic Press, San Diego
    • Parisien M, Dempster DW, Shane E, Bilezikian JP. Histomorphometric analysis of bone in primary hyperparathyroidism. In: Bilezikian JP, Marcus R, Levine MA (eds) The Parathyroids. Basic and Clinical Concepts. Academic Press, San Diego; 2001:423-436.
    • (2001) The Parathyroids. Basic and Clinical Concepts , pp. 423-436
    • Parisien, M.1    Dempster, D.W.2    Shane, E.3    Bilezikian, J.P.4
  • 4
    • 0034455103 scopus 로고    scopus 로고
    • Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
    • Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev 2000; 21:115-137.
    • (2000) Endocr Rev , vol.21 , pp. 115-137
    • Manolagas, S.C.1
  • 6
    • 10744231292 scopus 로고    scopus 로고
    • Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism
    • Bellido T, Ali AA, Plotkin LI, Fu Q, Gubrij I, Roberson PK, Weinstein RS, O'Brien CA, Manolagas SC, Jilka RL. Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism. J Biol Chem 2003; 278:50259-50272.
    • (2003) J Biol Chem , vol.278 , pp. 50259-50272
    • Bellido, T.1    Ali, A.A.2    Plotkin, L.I.3    Fu, Q.4    Gubrij, I.5    Roberson, P.K.6    Weinstein, R.S.7    O'Brien, C.A.8    Manolagas, S.C.9    Jilka, R.L.10
  • 7
    • 1842690566 scopus 로고    scopus 로고
    • Cbfa1/RUNX2 directs specific expression of the sclerosteosis gene (SOST)
    • Sevetson B, Taylor S, Pan Y. Cbfa1/RUNX2 directs specific expression of the sclerosteosis gene (SOST). J Biol Chem 2004; 279:13849-13858.
    • (2004) J Biol Chem , vol.279 , pp. 13849-13858
    • Sevetson, B.1    Taylor, S.2    Pan, Y.3
  • 8
    • 26844521277 scopus 로고    scopus 로고
    • Chronic elevation of PTH in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblasto-genesis
    • Bellido T, Ali AA, Gubrij I, Plotkin LI, Fu Q, O'Brien CA, Manolagas SC, Jilka RL. Chronic elevation of PTH in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblasto-genesis. Endocrinology 2005; 146:4577-4583.
    • (2005) Endocrinology , vol.146 , pp. 4577-4583
    • Bellido, T.1    Ali, A.A.2    Gubrij, I.3    Plotkin, L.I.4    Fu, Q.5    O'Brien, C.A.6    Manolagas, S.C.7    Jilka, R.L.8
  • 9
    • 21844467220 scopus 로고    scopus 로고
    • SOST is a target gene for PTH in bone
    • Keller H, Kneissel M. SOST is a target gene for PTH in bone. Bone 2005; 37:148-158.
    • (2005) Bone , vol.37 , pp. 148-158
    • Keller, H.1    Kneissel, M.2
  • 10
    • 0042554072 scopus 로고    scopus 로고
    • Cellular actions of parathyroid hormone on osteoblast and osteoclast differentiation
    • Bilezikian JP, Marcus R, Levine MA (eds) Academic Press, San Diego
    • Aubin JE, Heersche JNM. Cellular actions of parathyroid hormone on osteoblast and osteoclast differentiation. In: Bilezikian JP, Marcus R, Levine MA (eds) The Parathyroids. Basic and Clinical Concepts. Academic Press, San Diego; 2001:199-211.
    • (2001) The Parathyroids. Basic and Clinical Concepts , pp. 199-211
    • Aubin, J.E.1    Heersche, J.N.M.2
  • 11
    • 1542792345 scopus 로고
    • Modulation of type β transforming growth factor activity in bone cultures by osteotropic hormones
    • Pfeilschifter J, Mundy GR. Modulation of type β transforming growth factor activity in bone cultures by osteotropic hormones. Proc Natl Acad Sci USA 1987; 84:2024-2028.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2024-2028
    • Pfeilschifter, J.1    Mundy, G.R.2
  • 12
    • 0028943780 scopus 로고
    • A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia
    • Schipani E, Kruse Y, Juppner H. A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia. Science 1995; 268:98-100.
    • (1995) Science , vol.268 , pp. 98-100
    • Schipani, E.1    Kruse, Y.2    Juppner, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.