SLC4A11 prevents osmotic imbalance leading to corneal endothelial dystrophy, deafness, and polyuria

Journal of Biological Chemistry

Volumn 285, Issue 19, 2010, Pages 14467-14474

  Gröger, Nicole ^a   Fröhlich, Henning ^a,d   Maier, Hannes ^b   Olbrich, Andrea ^c   Kostin, Sawa ^a   Braun, Thomas ^a   Boettger, Thomas ^a  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CORNEAL STROMA; COUNTER CURRENT; ENDOCOCHLEAR POTENTIALS; FIBROCYTES; FLUID CONTENT; HYDROXYL ION; IN-VITRO; INNER EAR; ION CONCENTRATIONS; ION TRANSPORTERS; MOLECULAR MECHANISM; MORPHOLOGICAL CHANGES; POTASSIUM CONCENTRATIONS; THERAPEUTIC INTERVENTION;

BLOOD VESSEL PROSTHESES; ENDOTHELIAL CELLS; FIBROBLASTS; IONS; MORPHOLOGY; SELF ASSEMBLY; SODIUM CHLORIDE;

CONCENTRATION (PROCESS);

CARRIER PROTEIN; POTASSIUM; SODIUM CHLORIDE; SOLUTE CARRIER FAMILY 4 MEMBER 11; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA DYSTROPHY; CORNEA ENDOTHELIUM; CORNEA STROMA; ENDOLYMPH; ENDOTHELIUM CELL; HEARING IMPAIRMENT; HENLE LOOP; KIDNEY CONCENTRATING CAPACITY; MOUSE; NONHUMAN; OSMOSIS; PATHOPHYSIOLOGY; POLYURIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRIA VASCULARIS;

ANIMALS; ANION TRANSPORT PROTEINS; DEAFNESS; EAR, INNER; ENDOLYMPH; FEMALE; FUCHS' ENDOTHELIAL DYSTROPHY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSMOSIS; POLYURIA; POTASSIUM; SODIUM CHLORIDE; SUBCELLULAR FRACTIONS; SYMPORTERS;

EID: 77951995218     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.094680     Document Type: Article

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