Cytokine Protein Expression Levels in Tracheobronchial Lymph Node Homogenates of Pigs Infected with Pseudorabies Virus

Clinical and Vaccine Immunology

Volumn 17, Issue 5, 2010, Pages 728-734

  Miller, Laura C ^a   Zanella, Eraldo L ^b   Waters, W Ray ^c   Lager, Kelly M ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b UNIVERSITY OF PASSO FUNDO   (Brazil)

^c NATIONAL ANIMAL DISEASE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BACTERIAL STRAIN; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXPERIMENTAL PIG; HERPES VIRUS INFECTION; HISTOPATHOLOGY; IMMUNOMODULATION; LYMPH NODE; LYMPHATIC DRAINAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDORABIES HERPETOVIRUS; TISSUE HOMOGENATE; TRACHEOBRONCHIAL LYMPH NODE; VIRUS ISOLATION; VIRUS PATHOGENESIS;

ANIMALS; CYTOKINES; FLORIDA; FLOW CYTOMETRY; GENE EXPRESSION; HERPESVIRUS 1, SUID; LYMPH NODES; LYMPHOCYTE SUBSETS; PSEUDORABIES; SWINE; SWINE DISEASES;

EID: 77951985025     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00485-09     Document Type: Article

References (50)

1. Akira, S., K. Takeda, and T. Kaisho. 2001. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2:675-680.
2. Animal and Plant Health Inspection Service. 2009. Animal health monitoring and surveillance. Status of reportable diseases in the United States. Animal and Plant Health Inspection Service, U.S. Department of Agriculture.
3. Anonymous. 15 June 2007. Wisconsin responds to pseudorabies cases. JAVMA News. http://www.avma.org/onlnews/javma/jun07/070615r.asp.
4. Ben-Porat, T., J. M. DeMarchi, B. Lomniczi, and A. S. Kaplan. 1986. Role of glycoproteins of pseudorabies virus in eliciting neutralizing antibodies. Virology 154:325-334.
5. Bianchi, A. T., H. W. Moonen-Leusen, F. J. van Milligen, H. F. Savelkoul, R. J. Zwart, and T. G. Kimman. 1998. A mouse model to study immunity against pseudorabies virus infection: significance of CD4+ and CD8+ cells in protective immunity. Vaccine 16:1550-1558.
6. Biron, C. A., and G. C. Sen. 2007. Innate response to viral infections, p. 249-278. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, S. E. Straus, M. A. Martin, and B. Roizman (ed.), Fields virology, vol. 1, 5th ed. Wolters Kluwer Lippincott Williams & Wilkins, Philadelphia, PA.
7. Bouma, A., R. J. Zwart, M. G. De Bruin, M. C. De Jong, T. G. Kimman, and A. T. Bianchi. 1997. Immunohistological characterization of the local cellular response directed against pseudorabies virus in pigs. Vet. Microbiol. 58:145-154.
8. Brukman, A., and L. W. Enquist. 2006. Suppression of the interferon-mediated innate immune response by pseudorabies virus. J. Virol. 80:6345-6356.
9. De Bruin, M. G., Y. E. De Visser, T. G. Kimman, and A. T. Bianchi. 1998. Time course of the porcine cellular and humoral immune responses in vivo against pseudorabies virus after inoculation and challenge: significance of in vitro antigenic restimulation. Vet. Immunol. Immunopathol. 65:75-87.
10. de Bruin, T. G., E. M. van Rooij, Y. E. de Visser, J. J. Voermans, J. N. Samsom, T. G. Kimman, and A. T. Bianchi. 2000. Discrimination of different subsets of cytolytic cells in pseudorabies virus-immune and naive pigs. J. Gen. Virol. 81:1529-1537.
11. Denton, A. E., P. C. Doherty, S. J. Turner, and N. L. La Gruta. 2007. IL-18, but not IL-12, is required for optimal cytokine production by influenza virus-specific CD8+ T cells. Eur. J. Immunol. 37:368-375.
12. Diaz de Arce, H., K. Artursson, R. L'Haridon, A. Perers, C. La Bonnardiere, and G. V. Alm. 1992. A sensitive immunoassay for porcine interferon-alpha. Vet. Immunol. Immunopathol. 30:319-327.
13. Dinarello, C. A. 1999. Interleukin-18. Methods 19:121-132.
14. Dory, D., T. Fischer, V. Beven, R. Cariolet, H. J. Rziha, and A. Jestin. 2006. Prime-boost immunization using DNA vaccine and recombinant orf virus protects pigs against pseudorabies virus (herpes suid 1). Vaccine 24:6256-6263.
15. Feduchi, E., M. A. Alonso, and L. Carrasco. 1989. Human gamma interferon and tumor necrosis factor exert a synergistic blockade on the replication of herpes simplex virus. J. Virol. 63:1354-1359.
16. Fischer, T., M. Buttner, and H. J. Rziha. 2000. T helper 1-type cytokine transcription in peripheral blood mononuclear cells of pseudorabies virus (suid herpesvirus 1)-primed swine indicates efficient immunization. Immunology 101:378-387.
17. Fortin, C. F., T. Ear, and P. P. McDonald. 2009. Autocrine role of endogenous interleukin-18 on inflammatory cytokine generation by human neutrophils. FASEB J. 23:194-203.
18. Greenberger, M. J., R. M. Strieter, S. L. Kunkel, J. M. Danforth, R. E. Goodman, and T. J. Standiford. 1995. Neutralization of IL-10 increases survival in a murine model of Klebsiella pneumoniae. J. Immunol. 155:722-729.
19. Grob, P., V. E. Schijns, M. F. van den Broek, S. P. Cox, M. Ackermann, and M. Suter. 1999. Role of the individual interferon systems and specific immunity in mice in controlling systemic dissemination of attenuated pseudorabies virus infection. J. Virol. 73:4748-4754. (Pubitemid 29246734)
20. Hahn, E. C., G. R. Page, P. S. Hahn, K. D. Gillis, C. Romero, J. A. Annelli, and E. P. Gibbs. 1997. Mechanisms of transmission of Aujeszky's disease virus originating from feral swine in the USA. Vet. Microbiol. 55:123-130.
21. Halbur, P. G., P. S. Paul, M. L. Frey, J. Landgraf, K. Eernisse, X. J. Meng, M. A. Lum, J. J. Andrews, and J. A. Rathje. 1995. Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet. Pathol. 32:648-660.
22. Kim, Y. M., J. Y. Im, S. H. Han, H. S. Kang, and I. Choi. 2000. IFN-gamma up-regulates IL-18 gene expression via IFN consensus sequence-binding protein and activator protein-1 elements in macrophages. J. Immunol. 165:3198-3205.
23. Kimman, T. G., T. M. De Bruin, J. J. Voermans, B. P. Peeters, and A. T. Bianchi. 1995. Development and antigen specificity of the lymphoproliferation responses of pigs to pseudorabies virus: dichotomy between secondary B- and T-cell responses. Immunology 86:372-378.
24. Kimman, T. G., T. G. DeBruin, J. J. Voermans, and A. T. Bianchi. 1996. Cell-mediated immunity to pseudorabies virus: cytolytic effector cells with characteristics of lymphokine-activated killer cells lyse virus-infected and glycoprotein gB- and gC-transfected L14 cells. J. Gen. Virol. 77(Pt 5):987-990.
25. Liu, B., I. Mori, M. J. Hossain, L. Dong, K. Takeda, and Y. Kimura. 2004. Interleukin-18 improves the early defence system against influenza virus infection by augmenting natural killer cell-mediated cytotoxicity. J. Gen. Virol. 85:423-428.
26. Ma, W., K. M. Lager, J. A. Richt, W. C. Stoffregen, F. Zhou, and K. J. Yoon. 2008. Development of real-time polymerase chain reaction assays for rapid detection and differentiation of wild-type pseudorabies and gene-deleted vaccine viruses. J. Vet. Diagn. Invest. 20:440-447.
27. Marchioli, C. C., R. J. Yancey, Jr., E. A. Petrovskis, J. G. Timmins, and L. E. Post. 1987. Evaluation of pseudorabies virus glycoprotein gp50 as a vaccine for Aujeszky's disease in mice and swine: expression by vaccinia virus and Chinese hamster ovary cells. J. Virol. 61:3977-3982.
28. Mateu de Antonio, E., R. J. Husmann, R. Hansen, J. K. Lunney, D. Strom, S. Martin, and F. A. Zuckermann. 1998. Quantitative detection of porcine interferon-gamma in response to mitogen, superantigen and recall viral antigen. Vet. Immunol. Immunopathol. 61:265-277.
29. Mettenleiter, T. C. 1996. Immunobiology of pseudorabies (Aujeszky's disease). Vet. Immunol. Immunopathol. 54:221-229.
30. Mettenleiter, T. C. 1994. Pseudorabies (Aujeszky's disease) virus: state of the art. August 1993. Acta Vet. Hung. 42:153-177.
31. Mettenleiter, T. C., N. Lukacs, and H. J. Rziha. 1985. Pseudorabies virus avirulent strains fail to express a major glycoprotein. J. Virol. 56:307-311.
32. Nakamura, K., H. Okamura, K. Nagata, T. Komatsu, and T. Tamura. 1993. Purification of a factor which provides a costimulatory signal for gamma interferon production. Infect. Immun. 61:64-70.
33. Ober, B. T., A. Summerfield, C. Mattlinger, K. H. Wiesmuller, G. Jung, E. Pfaff, A. Saalmuller, and H. J. Rziha. 1998. Vaccine-induced, pseudorabies virus-specific, extrathymic CD4+CD8+ memory T-helper cells in swine. J. Virol. 72:4866-4873.
34. Onyekaba, C., L. Bueon, P. King, J. Fahrmann, and S. M. Goyal. 1987. Susceptibility of various cell culture systems to pseudorabies virus. Comp. Immunol. Microbiol. Infect. Dis. 10:163-166.
35. Page, G. R., F. I. Wang, and E. C. Hahn. 1992. Interaction of pseudorabies virus with porcine peripheral blood lymphocytes. J. Leukoc. Biol. 52:441-448.
36. Romero, C. H., P. Meade, J. Santagata, K. Gillis, G. Lollis, E. C. Hahn, and E. P. Gibbs. 1997. Genital infection and transmission of pseudorabies virus in feral swine in Florida, USA. Vet. Microbiol. 55:131-139.
37. Romero, C. H., P. N. Meade, B. L. Homer, J. E. Shultz, and G. Lollis. 2003. Potential sites of virus latency associated with indigenous pseudorabies viruses in feral swine. J. Wildl. Dis. 39:567-575.
38. Romero, C. H., P. N. Meade, J. E. Shultz, H. Y. Chung, E. P. Gibbs, E. C. Hahn, and G. Lollis. 2001. Venereal transmission of pseudorabies viruses indigenous to feral swine. J. Wildl. Dis. 37:289-296.
39. Schijns, V. E., R. Van der Neut, B. L. Haagmans, D. R. Bar, H. Schellekens, and M. C. Horzinek. 1991. Tumour necrosis factor-alpha, interferon-gamma and interferon-beta exert antiviral activity in nervous tissue cells. J. Gen. Virol. 72(Pt 4):809-815.
40. Stabel, T. J., S. R. Bolin, B. A. Pesch, and T. E. Rahner. 2000. A simple and rapid flow cytometric method for detection of porcine cell surface markers. J. Immunol. Methods 245:147-152.
41. Stasakova, J., B. Ferko, C. Kittel, S. Sereinig, J. Romanova, H. Katinger, and A. Egorov. 2005. Influenza A mutant viruses with altered NS1 protein function provoke caspase-1 activation in primary human macrophages, resulting in fast apoptosis and release of high levels of interleukins 1beta and 18. J. Gen. Virol. 86:185-195.
42. Suradhat, S., R. Thanawongnuwech, and Y. Poovorawan. 2003. Upregulation of IL-10 gene expression in porcine peripheral blood mononuclear cells by porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 84:453-459.
43. Takeda, K., H. Tsutsui, T. Yoshimoto, O. Adachi, N. Yoshida, T. Kishimoto, H. Okamura, K. Nakanishi, and S. Akira. 1998. Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity 8:383-390.
44. Williams, P. P. 1995. Study of immune function in inbred miniature pigs vaccinated and challenged with suid herpesvirus 1. Can. J. Vet. Res. 59:285-293.
45. Yao, Q., P. Qian, Y. Cao, Y. He, Y. Si, Z. Xu, and H. Chen. 2007. Synergistic inhibition of pseudorabies virus replication by porcine alpha/beta interferon and gamma interferon in vitro. Eur. Cytokine Netw. 18:71-77.
46. Yoon, H. A., A. G. Aleyas, J. A. George, S. O. Park, Y. W. Han, J. H. Lee, H. Y. Kang, S. H. Kang, J. G. Cho, and S. K. Eo. 2006. Modulation of immune responses induced by DNA vaccine expressing glycoprotein B of pseudorabies virus via coadministration of IFN-gamma-associated cytokines. J. Interferon Cytokine Res. 26:730-738.
47. Yoshimoto, T., H. Okamura, Y. I. Tagawa, Y. Iwakura, and K. Nakanishi. 1997. Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells. Proc. Natl. Acad. Sci. U. S. A. 94:3948-3953.
48. Zuckermann, F. A. 2000. Aujeszky's disease virus: opportunities and challenges. Vet. Res. 31:121-131.
49. Zuckermann, F. A., S. Martin, R. J. Husmann, and J. Brandt. 1999. Use of interleukin 12 to enhance the cellular immune response of swine to an inactivated herpesvirus vaccine. Adv. Vet. Med. 41:447-461.
50. Zuckermann, F. A., L. Zsak, T. C. Mettenleiter, and T. Ben-Porat. 1990. Pseudorabies virus glycoprotein gIII is a major target antigen for murine and swine virus-specific cytotoxic T lymphocytes. J. Virol. 64:802-812.