Aggregation of Streptococcus pneumoniae by a pneumococcal capsular polysaccharide-specific human monoclonal IgM correlates with antibody efficacy In Vivo

Clinical and Vaccine Immunology

Volumn 17, Issue 5, 2010, Pages 713-721

  Fabrizio, Kevin ^a   Manix, Catherine ^a   Guimaraes̃, Allan J ^a   Nosanchuk, Joshua D ^a   Pirofski, Liise Anne ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL POLYSACCHARIDE; COMPLEMENT COMPONENT C3; IMMUNOGLOBULIN M ANTIBODY; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY A7; PNEUMOCOCCAL CAPSULAR POLYSACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIBODY SPECIFICITY; ARTICLE; BACTERICIDAL ACTIVITY; CELL PROLIFERATION; COLONY FORMING UNIT; COMPLEMENT DEPOSITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; IN VIVO STUDY; INFECTION RESISTANCE; MALE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE; SURVIVAL RATE; SURVIVAL TIME; ULTRASOUND;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; BACTERIAL ADHESION; COLONY COUNT, MICROBIAL; COMPLEMENT SYSTEM PROTEINS; IMMUNOGLOBULIN M; MALE; MICE; MICE, INBRED C57BL; MICROBIAL VIABILITY; PHAGOCYTES; POLYSACCHARIDES, BACTERIAL; STREPTOCOCCUS PNEUMONIAE;

EID: 77951984874     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00410-09     Document Type: Article

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