Biocompatibility investigation of polyethylene glycol and alginate-poly-l-lysine for islet encapsulation

ASAIO Journal

Volumn 56, Issue 3, 2010, Pages 241-245

  Liu, Xiang Y ^a   Nothias, Jean Manuel ^a   Scavone, Andrew ^a   Garfinkel, Marc ^a   Millis, J Michael ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANATOMICAL LOCATIONS; POLY-L-LYSINE; RAT MODEL; T-TESTS; TIME POINTS; TWO-MATERIALS;

AMINO ACIDS; BIOCOMPATIBILITY; ENCAPSULATION; ETHYLENE; ETHYLENE GLYCOL; POLYETHYLENE OXIDES; REGRESSION ANALYSIS;

POLYETHYLENE GLYCOLS;

ALGINATE POLYLYSINE ALGINATE; ALGINIC ACID; DRUG DERIVATIVE; LYSINE; MACROGOL DERIVATIVE; POLYLYSINE;

ANIMAL; ARTICLE; CHEMISTRY; DRUG FORMULATION; LEWIS RAT; MALE; MICROCAPSULE; PROSTHESES AND ORTHOSES; RAT;

ALGINATES; ANIMALS; CAPSULES; DRUG COMPOUNDING; LYSINE; MALE; POLYETHYLENE GLYCOLS; POLYLYSINE; PROSTHESES AND IMPLANTS; RATS; RATS, INBRED LEW;

EID: 77951984756     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/MAT.0b013e3181d7b8e3     Document Type: Article

References (39)

1. Shapiro AM, Lakey JR, Ryan EA, et al : Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoidfree immunosuppressive regimen. N Engl J Med 343:343-230, 2000.
2. Nanji SA, Shapiro AM: Advances in pancreatic islet transplantation in humans. Diabetes Obes Metab 8:8-15, 2006.
3. Beck J, Angus R, Madsen B, et al : Islet encapsulation: Strategies to enhance islet cell functions. Tissue Eng 13:13-589, 2007.
4. Rayat GR, Gill RG: Pancreatic islet xenotransplantation: Barriers and prospects. Curr Diab Rep 3:3-336, 2003.
5. Elliott RB, Escobar L, Tan PL, et al : Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation. Xenotransplantation 14:14-157, 2007.
6. de Groot M, Schuurs TA, van Schilfgaarde R: Causes of limited survival of microencapsulated pancreatic islet grafts. J Surg Res 121:121-141, 2004.
7. Fritschy WM, de Vos P, Groen H, et al : The capsular overgrowth on microencapsulated pancreatic islet grafts in streptozotocin and autoimmune diabetic rats. Transpl Int 7:7-264, 1994.
8. de Vos P, Wolters GH, van Schilfgaarde R: Possible relationship between fibrotic overgrowth of alginate-polylysine-alginate microencapsulated pancreatic islets and the microcapsule integrity. Transplant Proc 26:26-782, 1994.
9. De Vos P, Van Straaten JF, Nieuwenhuizen AG, et al : Why do microencapsulated islet grafts fail in the absence of fibrotic overgrowth? Diabetes 48:48-1381, 1999.
10. Hou QP, Bae YH: Biohybrid artificial pancreas based on macrocapsule device. Adv Drug Deliv Rev 35:35-271, 1999.
11. Ronel SH, D'Andrea MJ, Hashiguchi H, et al : Macroporous hydrogel membranes for a hybrid artificial pancreas. I. Synthesis and chamber fabrication. J Biomed Mater Res 17:17-855, 1983.
12. Gin H, Dupuy B, Baquey C, et al: Agarose encapsulation of islets of Langerhans: Reduced toxicity in vitro. J Microencapsul 4:4-239, 1987.
13. Shimizu S, Yamazaki M, Kubota S, et al: In vitro studies on a new method for islet microencapsulation using a thermoreversible gelation polymer, N-isopropylacrylamide-based copolymer. Artif Organs 20:20-1232, 1996.
14. Sawhney AS, Pathak CP, Hubbell JA: Interfacial photopolymerization of poly (ethylene glycol)-based hydrogels upon alginate-poly (L-Lysine) microcapsules for enhanced biocompatibility. Biomaterials 14:14-1008, 1993.
15. Liu J, Pan T, Woolley AT, Lee ML: Surface-modified poly (methyl methacrylate) capillary electrophoresis microchips for protein and peptide analysis. Anal Chem 76:76-6948, 2004.
16. Schaffellner S, Stadlbauer V, Stiegler P, et al: Porcine islet cells microencapsulated in sodium cellulose sulfate. Transplant Proc 37:37-248, 2005.
17. Campos-Lisboa AC, Mares-Guia TR, Grazioli G, et al: Biodritin microencapsulated human islets of Langerhans and their potential for type 1 diabetes mellitus therapy. Transplant Proc 40:40-433, 2008.
18. Teramura Y, Iwata H: Islet encapsulation with living cells for improvement of biocompatibility. Biomaterials 30:2270-2275, 2005.
19. Waldeck H, Chung AS, Kao WJ: Interpenetrating polymer networks containing gelatin modified with PEGylated RGD and soluble KGF: Synthesis, characterization, and application in in vivo critical dermal wound. J Biomed Mater Res A 82:861-871, 2007.
20. Tessmar JK, Gopferich AM: Customized PEG-derived copolymers for tissue-engineering applications. Macromol Biosci 7:7-23, 2007.
21. Hoffmann J, Groll J, Heuts J, et al: Blood cell and plasma protein repellent properties of star-PEG-modified surfaces. J Biomater Sci Polym Ed 17:17-985, 2006.
22. Mougin K, Ham AS, Lawrence MB, et al: Construction of a tethered poly (ethylene glycol) surface gradient for studies of cell adhesion kinetics. Langmuir 21:21-4809, 2005.
23. Oyewumi MO, Yokel RA, Jay M, et al: Comparison of cell uptake, biodistribution and tumor retention of folate-coated and PEG-coated gadolinium nanoparticles in tumor-bearing mice. J Control Release 95:95-613, 2004.
24. Lin-Gibson S, Bencherif S, Cooper JA, et al: Synthesis and characterization of PEG dimethacrylates and their hydrogels. Biomacromolecules 5:5-1280, 2004.
25. Beuneu C, Vosters O, Movahedi B, et al: Human pancreatic duct cells exert tissue factor-dependent procoagulant activity: relevance to islet transplantation. Diabetes 53:53-1407, 2004.
26. Kizilel S, Garfinkel M, Opara E: The bioartificial pancreas: Progress and challenges. Diabetes Technol Ther 7:7-968, 2005.
27. Wyman JL, Kizilel S, Skarbek R, et al: Immunoisolating pancreatic islets by encapsulation with selective withdrawal. Small 3:3-683, 2007.
28. Hobbs HA, Kendall WF Jr, Darrabie M, Opara EC: Prevention of morphological changes in alginate microcapsules for islet xenotransplantation. J Investig Med 49:49-572, 2001.
29. De Vos P, De Haan B, Van Schilfgaarde R: Effect of the alginate composition on the biocompatibility of alginate-polylysine microcapsules. Biomaterials 18:18-273, 1997.
30. Bakeine GJ, Bertolotti A, Latina M, et al: Surface properties and implantation site affect the capsular fibrotic overgrowth. J Biomed Mater Res A 83:83-965, 2007.
31. De Heer E, Sijpkens YW, Verkade M, et al: Morphometry of interstitial fibrosis. Nephrol Dial Transplant 15:15-72, 2000.
32. Clayton HA, London NJ, Colloby PS, et al: The effect of capsule composition on the biocompatibility of alginate-poly-L-lysine capsules. J Microencapsul 8:8-221, 1991.
33. Kulseng B, Skjak-Braek G, Ryan L, et al: Transplantation of alginate microcapsules: Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation 67:67-978, 1999.
34. Orive G, Tam SK, Pedraz JL, Halle JP: Biocompatibility of alginatepoly-L-Lysine microcapsules for cell therapy. Biomaterials 27:27-3691, 2006.
35. Stabler C, Wilks K, Sambanis A, Constantinidis I: The effects of alginate composition on encapsulated betaTC3 cells. Biomaterials 22:22-1301, 2001.
36. Andrade JD, Nagoaka S, Cooper S, et al: Surfaces and blood biocompatibility. Current hypothesis. ASAIO Trans 10:10-75, 1987.
37. Chen J, Chu I, Shiao M, et al: Microencapsulation of islets in PEG-amine modified alginate-poly (L-Lysine)-alginate microcapsules for constructing bioartificial pancreas. J Ferment Bioeng 86:86-185, 1998.
38. Wijsman J, Atkison P, Mazaheri R, et al: Histological and immunopathological analysis of recovered encapsulated allogeneic islets from transplanted diabetic BB/W rats. Transplantation 54:54-588, 1992.
39. Luca G, Calvitti M, Nastruzzi C, et al: Encapsulation, in vitro characterization, and in vivo biocompatibility of Sertoli cells in alginate-based microcapsules. Tissue Eng 13:13-641, 2007.