Human pancreatic duct cells exert tissue factor-dependent procoagulant activity: Relevance to islet transplantation

Diabetes

Volumn 53, Issue 6, 2004, Pages 1407-1411

  Beuneu, Claire ^a,b   Vosters, Olivier ^a,b   Movahedi, Babak ^b,c   Remmelink, Myriam ^a   Salmon, Isabelle ^a   Pipeleers, Daniel ^b,c   Pradier, Olivier ^a   Goldman, Michel ^a,b   Verhasselt, Valérie ^a,b  

^a ERASME HOSPITAL   (Belgium)

^b Juven Diabetes Research Foundation   (Belgium)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7; PROCOAGULANT; THROMBOPLASTIN;

ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; FLOW CYTOMETRY; GRAFT REJECTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PANCREAS CELL; PANCREAS DUCT; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOSIS;

BLOOD COAGULATION TESTS; CELLS, CULTURED; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS TRANSPLANTATION; PANCREATIC DUCTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THROMBOPLASTIN;

EID: 2542521695     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.6.1407     Document Type: Article

References (21)

1. Ryan EA, Lakey JR, Rajotte RV, Korbutt GS, Kin T, Imes S, Rabinovitch A, Elliott JF, Bigam D, Kneteman NM, Warnock GL, Larsen I, Shapiro AM: Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 50:710-719, 2001
2. Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM, Rajotte RV: Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343:230-238, 2000
3. Bennet W, Sundberg B, Groth CG, Brendel MD, Brandhorst D, Brandhorst H, Bretzel RG, Elgue G, Larsson R, Nilsson B, Korsgren O: Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation? Diabetes 48: 1907-1914, 1999
4. Ozmen L, Ekdahl KN, Elgue G, Larsson R, Korsgren O, Nilsson B: Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation. Diabetes 51:1779-1784, 2002
5. Moberg L, Johansson H, Lukinius A, Berne C, Foss A, Kallen R, Ostraat O, Salmela K, Tibell A, Tufveson G, Elgue G, Nilsson EK, Korsgren O, Nilsson B: Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation. Lancet 360:2039-2045, 2002
6. Shapiro AM, Lakey JR, Rajotte RV, Warnock GL, Friedlich MS, Jewell LD, Kneteman NM: Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft. Transplantation 59:1060-1063, 1995
7. Ling Z, Pipeleers DG: Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation. J Clin Invest 98:2805-2812, 1996
8. Keymeulen B, Ling Z, Gorus FK, Delvaux G, Bouwens L, Grupping A, Hendrieckx C, Pipeleers-Marichal M, Van Schravendijk C, Salmela K, Pipeleers DG: Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft. Diabetologia 41:452-459, 1998
9. Pavlovic D, Chen MC, Bouwens L, Eizirik DL, Pipeleers D: Contribution of ductal cells to cytokine responses by human pancreatic islets. Diabetes 48:29-33, 1999
10. Vosters O, Beuneu C, Nagy N, Movahedi B, Aksoy E, Salmon I, Pipeleers D, Goldman M, Verhasselt V: CD40 expression on human pancreatic duct cells: role in nuclear factor-kappa B activation and production of proinflammatory cytokines. Diabetologia. In press
11. De Breuck S, Lardon J, Rooman I, Bouwens L: Netrin-1 expression in fetal and regenerating rat pancreas and its effect on the migration of human pancreatic duct and porcine islet precursor cells. Diabetologia 46:926-933, 2003
12. Bogdanov VY, Balasubramanian V, Hathcock J, Vele O, Lieb M, Nemerson Y: Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. Nat Med 9:458-462, 2003
13. Kakkar AK, Lemoine NR, Scully MF, Tebbutt S, Williamson RC: Tissue factor expression correlates with histological grade in human pancreatic cancer. Br J Surg 82:1101-1104, 1995
14. Luther T, Flossel C, Mackman N, Bierhaus A, Kasper M, Albrecht S, Sage EH, Iruela-Arispe L, Grossmann H, Strohlein A, Zhang Y, Nawroth PP, Carmeliet P, Loskutoff DJ, Muller M: Tissue factor expression during human and mouse development. Am J Pathol 149:101-113, 1996
15. Luther T, Flossel C, Albrecht S, Kotzsch M, Muller M: Tissue factor expression in normal and abnormal mammary gland (Letter). Nat Med 2:491-492, 1996
16. Sugawara T, Yamabe H, Osawa H, Kaizuka M, Shirato K, Nakamura M, Tamura M, Okumura K: Tissue factor pathway inhibitor production by human proximal tubular epithelial cells in culture. Thromb Res 110:141-147, 2003
17. Giesen PL, Rauch U, Bohrmann B, Kling D, Roque M, Fallon JT, Badimon JJ, Himber J, Riederer MA, Nemerson Y: Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci U S A 96:2311-2315, 1999
18. Franklin WA, Schulak JA, Reckard CR: The fate of transplanted pancreatic islets in the rat. Am J Pathol 94:85-95, 1979
19. Dugina TN, Kiseleva EV, Chistov IV, Umarova BA, Strukova SM: Receptors of the PAR family as a link between blood coagulation and inflammation. Biochemistry (Mosc) 67:65-74, 2002
20. Bokarewa MI, Morrissey JH, Tarkowski A: Tissue factor as a proinflammatory agent. Arthritis Res 4:190-195, 2002
21. Le Moine A, Goldman M: Contributions of innate immunity to allograft rejection and survival. Curr Opin Organ Tranplant 8:2-6, 2003