Molecular dynamics simulation of the effect of ligand homogeneity on protein behavior in hydrophobic charge induction chromatography

Journal of Molecular Graphics and Modelling

Volumn 28, Issue 8, 2010, Pages 863-869

  Zhang, Lin ^a   Bai, Shu ^a   Sun, Yan ^a  

^a TIANJIN UNIVERSITY   (China)

Author keywords

Adsorption; Elution; Irreversibility; Molecular dynamics; Protein chromatography; Protein unfolding

Indexed keywords

ADSORPTION CHROMATOGRAPHY; AXIAL DIRECTION; COARSE GRAINED MODELS; COARSE-GRAINED; CONFORMATIONAL TRANSITIONS; ELECTROSTATIC REPULSION; EXPERIMENTAL TECHNIQUES; HETEROGENEOUS DISTRIBUTIONS; HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHIES; HYDROPHOBIC INTERACTIONS; IN-LINE; LIGAND DENSITY; MATRIX; MICROSCOPIC BEHAVIOR; MOLECULAR DYNAMICS SIMULATIONS; PARAMETER OPTIMIZATION; PORE MODELS; POROUS ADSORBENT; PROTEIN ADSORPTION; PROTEIN BEHAVIOR; PROTEIN CHROMATOGRAPHY; PROTEIN CONFORMATION; PROTEIN ORIENTATION; PROTEIN UNFOLDING; RATIONAL DESIGN; STABLE ADSORPTION;

ADSORBENTS; COMPUTER SIMULATION; DESORPTION; DYNAMICS; HYDROPHOBIC CHROMATOGRAPHY; HYDROPHOBICITY; LIGANDS; MOLECULAR DYNAMICS; PROTEINS; STRUCTURAL OPTIMIZATION;

ADSORPTION;

ADSORPTION; ADSORPTION CHROMATOGRAPHY; ARTICLE; CHEMICAL BOND; CHEMICAL INTERACTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DESORPTION; ELUTION; HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHY; HYDROPHOBICITY; MICROSCOPY; MOLECULAR DYNAMICS; MORPHOLOGY; POROSITY; PRIORITY JOURNAL; PROTEIN CONFORMATION; STATIC ELECTRICITY;

ADSORPTION; CHROMATOGRAPHY; HYDROPHOBICITY; LIGANDS; MOLECULAR DYNAMICS SIMULATION; POROSITY; PROTEIN CONFORMATION; PROTEINS; SURFACE PROPERTIES;

EID: 77951978883     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmgm.2010.03.006     Document Type: Article

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