Low flow-mediated constriction occurs in the radial but not the brachial artery in healthy pregnant and nonpregnant women

Journal of Applied Physiology

Volumn 108, Issue 5, 2010, Pages 1097-1105

  Weissgerber, Tracey L ^a   Davies, Gregory A L ^b   Tschakovsky, Michael E ^b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

Conduit artery vascular function; Human pregnancy; Physical activity

Indexed keywords

ADULT; ARTICLE; BLOOD FLOW; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BRACHIAL ARTERY; COMPARATIVE STUDY; DOPPLER FLOWMETRY; ECHOGRAPHY; EXERCISE TEST; FEMALE; GESTATIONAL AGE; HEART RATE; HUMAN; HYPEREMIA; MOTOR ACTIVITY; PATHOPHYSIOLOGY; PHOTOELECTRIC PLETHYSMOGRAPHY; PREGNANCY; PREGNANCY COMPLICATION; RADIAL ARTERY; SEDENTARY LIFESTYLE; VASOCONSTRICTION;

ADULT; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BRACHIAL ARTERY; EXERCISE TEST; FEMALE; GESTATIONAL AGE; HEART RATE; HUMANS; HYPEREMIA; MOTOR ACTIVITY; PHOTOPLETHYSMOGRAPHY; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; RADIAL ARTERY; REGIONAL BLOOD FLOW; SEDENTARY LIFESTYLE; ULTRASONOGRAPHY, DOPPLER; VASOCONSTRICTION; YOUNG ADULT;

EID: 77951966972     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00815.2009     Document Type: Article

References (43)

1. 1. Allen JD, Geaghan JP, Greenway F, Welsch MA. Time course of improved flow-mediated dilation after short-term exercise training. Med Sei Sports Exerc 35: 847-853, 2003. (Pubitemid 36547389)
2. Black MA, Cable NT, Thijssen DH, Green DJ. Importance of measuring the time course of flow-mediated dilatation in humans. Hypertension 51: 203-210, 2008.
3. 3. Bouchard C, Tremblay A, Leblanc C, Lortie G, Savard R, Theriault G. A method to assess energy expenditure in children and adults. Am J Clin Nutr 37: 461-467, 1983. (Pubitemid 13086430)
4. 4. Chapman AB, Abraham WT, Zamudio S, Coffin C, Merouani A, Young D, Johnson A, Osorio F, Goldberg C, Moore LG, Dahms T, Schrier RW. Temporal relationships between hormonal and hemodynamic changes in early human pregnancy. Kidney Int 54: 2056-2063, 1998. (Pubitemid 28533634)
5. 5. Corretti MC, Anderson TJ, Benjamin EJ, Celermajer D, Charbonneau F, Creager MA, Deanfield J, Drexler H, Gerhard-Herman M, Herrington D, Vallance P, Vita J, Vogel R. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 39: 257-265, 2002. (Pubitemid 34084631)
6. 6. de Simone G, Devereux RB, Chien S, Alderman MH, Atlas SA, Laragh JH. Relation of blood viscosity to demographic and physiologic variables and to cardiovascular risk factors in apparently normal adults. Circulation 81: 107-117, 1990. (Pubitemid 20031774)
7. 7. Dorup I, Skajaa K, Sorensen KE. Normal pregnancy is associated with enhanced endothelium-dependent flow-mediated vasodilation. Am J Physiol Heart Circ Physiol 276: H821-H825, 1999. (Pubitemid 29157453)
8. Dyson KS, Shoemaker JK, Hughson RL. Effect of acute sympathetic nervous system activation on flow-mediated dilation of brachial artery. Am J Physiol Heart Circ Physiol 290: H1446-H1453, 2006.
9. Faber-Swensson AP, O'Callaghan SP, Walters WA. Endothelial cell function enhancement in a late normal human pregnancy. Aust N Z J Obstet Gynaecol 44: 525-529, 2004.
10. Filitti V, Giral P, Simon A, Merli I, Del Pino M, Levenson J. Enhanced constriction of the peripheral large artery in response to acute induction of a low-flow state in human hypercholesterolemia. Arterioscler Thromb 11: 161-166, 1991.
11. Gori T, Dragoni S, Lisi M, Di Stolfo G, Sonnati S, Fineschi M, Parker JD. Conduit artery constriction mediated by low flow a novel noninvasive method for the assessment of vascular function. J Am Coll Cardiol 51: 1953-1958, 2008.
12. Gori T, Grotti S, Dragoni S, Lisi M, Di Stolfo G, Sonnati S, Fineschi M, Parker JD. Assessment of vascular function: flow-mediated constriction complements the information of flow-mediated dilatation. Heart 96: 141-147, 2010.
13. Greenwood JP, Scott EM, Stoker JB, Walker JJ, Mary DA. Sympathetic neural mechanisms in normal and hypertensive pregnancy in humans. Circulation 104: 2200-2204, 2001.
14. Heenan AP, Wolfe LA. Plasma acid-base regulation above and below ventilatory threshold in late gestation. J Appl Physiol 88: 149-157, 2000.
15. 15. Hijmering ML, Stroes ES, Olijhoek J, Hutten BA, Blankestijn PJ, Rabelink TJ. Sympathetic activation markedly reduces endotheliumdependent, flow-mediated vasodilation. J Am Coll Cardiol 39: 683-688, 2002. (Pubitemid 34158166)
16. 16. Huisman A, Aarnoudse JG, Heuvelmans JH, Goslinga H, Fidler V, Huisjes HJ, Zijlstra WG. Whole blood viscosity during normal pregnancy. Br J Obstet Gynaecol 94: 1143-1149, 1987. (Pubitemid 18058553)
17. Kemp JG, Greer FA, Wolfe LA. Acid-base regulation after maximal exercise testing in late gestation. J Appl Physiol 83: 644-651, 1997.
18. 18. Koller A, Kaley G. Endothelium regulates skeletal muscle microcirculation by a blood flow velocity-sensing mechanism. Am J Physiol Heart Circ Physiol 258: H916-H920, 1990. (Pubitemid 20103230)
19. Kremkau F. Diagnostic Ultrasound: Principles and Practice. Philadelphia, PA: Saunders, 1998.
20. Leung FP, Yung LM, Laher I, Yao X, Chen ZY, Huang Y. Exercise, vascular wall and cardiovascular diseases: an update (part 1). Sports Med 38: 1009-1024, 2008.
21. 21. Levenson J, Pessana F, Gariepy J, Armentano R, Simon A. Gender differences in wall shear-mediated brachial artery vasoconstriction and vasodilation. J Am Coll Cardiol 38: 1668-1674, 2001. (Pubitemid 33065453)
22. 22. McGowan CL, Levy AS, Millar PJ, Guzman JC, Morillo CA, McCartney N, Macdonald MJ. Acute vascular responses to isometric handgrip exercise and effects of training in persons medicated for hypertension. Am J Physiol Heart Circ Physiol 291: H1797-H1802, 2006. (Pubitemid 44497686)
23. 23. McGowan CL, Visocchi A, Faulkner M, Verduyn R, Rakobowchuk M, Levy AS, McCartney N, Macdonald MJ. Isometric handgrip training improves local flow-mediated dilation in medicated hypertensives. Eur J Appl Physiol 98: 355-362, 2006. (Pubitemid 44490058)
24. 24. Megnien JL, Simon A, Andriani A, Segond P, Jeannin S, Levenson J. Cholesterol lowering therapy inhibits the low-flow mediated vasoconstriction of the brachial artery in hypercholesterolaemic subjects. Br J Clin Pharmacol 42: 187-193, 1996. (Pubitemid 26255064)
25. 25. Moe IT, Hoven H, Hetland EV, Rognmo O, Slordahl SA. Endothelial function in highly endurance-trained and sedentary, healthy young women. Vasc Med 10: 97-102, 2005. (Pubitemid 40883246)
26. 26. Mullen MJ, Kharbanda RK, Cross J, Donald AE, Taylor M, Vallance P, Deanfleld JE, MacAllister RJ. Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia. Circ Res 88: 145-151, 2001. (Pubitemid 32147301)
27. Padilla J, Johnson BD, Newcomer SC, Wilhite DP, Mickleborough TD, Fly AD, Mather KJ, Wallace JP. Adjusting flow-mediated dilation for shear stress stimulus allows demonstration of endothelial dysfunction in a population with moderate cardiovascular risk. J Vase Res 46: 592-600, 2009.
28. Parker BA, Ridout SJ, Proctor DN. Age and flow-mediated dilation: a comparison of dilatory responsiveness in the brachial and popliteal arteries. Am J Physiol Heart Circ Physiol 291: H3043-H3049, 2006.
29. Preston RJ, Heenan AP, Wolfe LA. Physicochemical analysis of phasic menstrual cycle effects on acid-base balance. Am J Physiol Regul Integr Comp Physiol 280: R481-R487, 2001.
30. Pyke KE, Dwyer EM, Tschakovsky ME. Impact of controlling shear rate on flow-mediated dilation responses in the brachial artery of humans. J Appl Physiol 97: 499-508, 2004.
31. Pyke KE, Poitras V, Tschakovsky ME. Brachial artery flow-mediated dilation during handgrip exercise: evidence for endothelial transduction of the mean shear stimulus. Am J Physiol Heart Circ Physiol 294: H2669-H2679, 2008.
32. Pyke KE, Tschakovsky ME. Peak vs. total reactive hyperemia: which determines the magnitude of flow-mediated dilation? J Appl Physiol 102: 1510-1519, 2007.
33. Pyke KE, Tschakovsky ME. The relationship between shear stress and flow-mediated dilatation: implications for the assessment of endothelial function. J Physiol 568: 357-369, 2005.
34. Quinton AE, Cook CM, Peek MJ. A longitudinal study using ultrasound to assess flow-mediated dilatation in normal human pregnancy. Hypertens Pregnancy 26: 273-281, 2007.
35. 35. Saarelainen H, Laitinen T, Raitakari OT, Juonala M, Heiskanen N, Lyyra-Laitinen T, Viikari JS, Vanninen E, Heinonen S. Pregnancyrelated hyperlipidemia and endothelial function in healthy women. Circ J 70: 768-772, 2006. (Pubitemid 43797790)
36. Savvidou MD, Kametas NA, Donald AE, Nicolaides KH. Non-invasive assessment of endothelial function in normal pregnancy. Ultrasound Obstet Gynecol 15: 502-507, 2000.
37. 37. Silber HA, Ouyang P, Bluemke DA, Gupta SN, Foo TK, Lima JA. A novel method for assessing arterial endothelial function using phase contrast magnetic resonance imaging: vasoconstriction during reduced shear. J Cardiovasc Magn Reson 7: 615-621, 2005. (Pubitemid 41176826)
38. 38. Spieker LE, Luscher TF, Noll G. ETA receptors mediate vasoconstriction of large conduit arteries during reduced flow in humans. J Cardiovasc Pharmacol 42: 315-318, 2003. (Pubitemid 37071686)
39. Stadler RW, Ibrahim SF, Lees RS. Measurement of the time course of peripheral vasoactivity: results in cigarette smokers. Atherosclerosis 138: 197-205, 1998.
40. Tamariz LJ, Young JH, Pankow JS, Yeh HC, Schmidt MI, Astor B, Brancati FL. Blood viscosity and hematocrit as risk factors for type 2 diabetes mellitus: the atherosclerosis risk in communities (ARIC) study. Am J Epidemiol 168: 1153-1160, 2008.
41. Thijssen DH, van Bemmel MM, Bullens LM, Dawson EA, Hopkins ND, Tinken TM, Black MA, Hopman MT, Cable NT, Green DJ. The impact of baseline diameter on flow-mediated dilation differs in young and older humans. Am J Physiol Heart Circ Physiol 295: H1594-H1598, 2008.
42. Wolfe LA, Weissgerber TL. Clinical physiology of exercise in pregnancy: a literature review. J Obstet Gynaecol Can 25: 473-483, 2003.
43. 43. Woodman RJ, Playford DA, Watts GF, Cheetham C, Reed C, Taylor RR, Puddey IB, Beilin LJ, Burke V, Mori TA, Green D. Improved analysis of brachial artery ultrasound using a novel edge-detection software system. J Appl Physiol 91: 929-937, 2001. (Pubitemid 32681129)