Pregnancy-related hyperlipidemia and endothelial function in healthy women

Circulation Journal

Volumn 70, Issue 6, 2006, Pages 768-772

  Saarelainen, Heli ^a   Laitinen, Tomi ^a   Raitakari, Olli T ^b   Juonala, Markus ^b   Heiskanen, Nonna ^a   Lyyra Laitinen, Tiina ^a   Viikari, Jorma S A ^b   Vanninen, Esko ^a   Heinonen, Seppo ^a  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

Endothelial function; Flow mediated vasodilation; Hypercholesterolemia; Pregnancy

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ARTERY DIAMETER; ARTICLE; BRACHIAL ARTERY; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FEMALE; GESTATIONAL AGE; HUMAN; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; PREGNANCY; SMOKING; ULTRASOUND; UNIVARIATE ANALYSIS;

BLOOD FLOW VELOCITY; BRACHIAL ARTERY; CHOLESTEROL, HDL; CHOLESTEROL, LDL; ENDOTHELIUM, VASCULAR; FEMALE; GESTATIONAL AGE; HUMANS; HYPERLIPIDEMIAS; PREGNANCY; TRIGLYCERIDES; VASODILATION;

EID: 33744458200     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.70.768     Document Type: Article

References (26)

1. Chiang A-N, Yang M-L, Hung J-H, Chou P, Shyn S-K, Ng H-T. Alterations of serum lipid levels and their biological relevances during and after pregnancy. Life Sci 1995; 56: 2367-2375.
2. de Kleijn MJJ, van der Schouw YT, van der Graaf Y. Reproductive history and cardiovascular disease risk in postmenopausal women: A review of the literature. Maturitas 1999; 33: 7-36.
3. Ness RB, Harris T, Cobb J, Flegal KM, Kelsey JL, Balanger A, et al. Number of pregnancies and the subsequent risk of cardiovascular disease. N Engl J Med 1993; 328: 1528-1533.
4. Cockell AP, Poston L. Flow mediated vasodilation is enhanced in normal pregnancy but reduced in pre-eclampsia. Hypertension 1997; 30: 247-251.
5. Celermajer DS, Sorensen KE, Gooch VM, Spiegelhalter DJ, Miller OI, Sullivan ID, et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992; 340: 1111-1115.
6. Dørup I, Skajaa K, Sørensen KE. Normal pregnancy is associated with enhanced endothelium-dependent flow-mediated vasodilation. Am J Physiol Heart Circ Physiol 1999; 276: 821-825.
7. Bonetti PO, Lerman LO, Lerman A. Endothelial dysfunction: A marker of atherosclerotic risk. Arterioscler Thromb Vasc Biol 2003; 23: 168-175.
8. Savvidou MD, Hingorani AD, Tsikas D, Frölich JC, Vallance P, Nicolaides KH. Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia. Lancet 2003; 361: 1511-1517.
9. Esen AM, Barutcu I, Acar M, Degirmenci B, Kaya D, Turmen M, et al. Effect of smoking on endothelial function and wall thickness of brachial artery. Circ J 2004; 68: 1123-1126.
10. Benjamin EJ, Larson MG, Keyes MJ, Mitchell GF, Vasan RS, Keaney JF, et al. Clinical correlates and heritability of flow mediated dilation in the community: The Framingham heart study. Circulation 2004; 109: 613-619.
11. Creager MA, Cooke JP, Mendelsohn ME, Gallagher SJ, Coleman SM, Loscalzo J, et al. Impaired vasodilation of forearm resistance vessels in hypercholesterolaemic humans. J Clin Invest 1990; 86: 228-234.
12. Toikka JO, Ahotupa M, Viikari JSA, Niinikoski H, Taskinen MR, Irjala K, et al. Constantly low HDL-cholesterol concentration relates to endothelial dysfunction and increased in vivo LDL-oxidation in healthy young men. Atherosclerosis 1999; 147: 133-138.
13. Stroes ESG, Koomans HA, Rabelink TJ, de Bruin TWA. Vascular function in the forearm of hypercholesterolaemic patients off and on lipid-lowering medication. Lancet 1995; 346: 467-471.
14. Treasure CB, Klein LJ, Weintraub WS, Talley JD, Stillabower ME, Kosinski AS, et al. Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease. N Engl J Med 1995; 332: 481-487.
15. Bosch T, Wendler T. State of the art of low-density lipoprotein apheresis in the year 2003. Ther Apher Dial 2004; 8: 76-79.
16. Juonala M, Viikari JSA, Hutri-Kähönen N, Pietikäinen M, Jokinen E, Taittonen L, et al. The 21-year follow-up of the Cardiovascular Risk in Young Finns Study: Risk factor levels, secular trends and east-west difference. J Intern Med 2004; 255: 457-468.
17. Juonala M, Viikari JSA, Laitinen T, Marniemi J, Helenius H, Rönnemaa T, et al. Interrelations between brachial endothelial function and carotid intima-media thickness in young adults: The cardiovascular risk in young Finns study. Circulation 2004; 110: 2918-2923.
18. Desoye G, Schweditsch MO, Pfeiffer KP, Zechner R, Kostner GM. Correlation with lipid and lipoprotein levels during normal pregnancy and postpartum. J Clin Endocrinol Metab 1987; 64: 704-712.
19. Suwannaprapha P, Chaisri U, Riyong D, Maneerat Y. Improvement of function and morphology of tumor necrosis factor-alpha treated endothelial cells with 17-beta estradiol: A preliminary study for a feasible simple model for atherosclerosis. Circ J 2005; 69: 730-738.
20. Faber-Swensson AP, O'callaghan SP, Walters WA. Endothelial cell function enhancement in a late normal human pregnancy. Aust NZ J Obstet Gynaecol 2004; 44: 525-529.
21. Carbillon L, Uzan M, Uzan S. Pregnancy, vascular tone, and maternal hemodynamics: A crucial adaptation. Obstet Gynecol Surv 2000; 55: 574-581.
22. Silber HA, Ouyang P, Bluemke DA, Gupta SN, Foo TK, Lima JA. Why is flow-mediated dilation dependent on arterial size? Assessment of the shear stimulus using phase-contrast magnetic resonance imaging. Am J Physiol Heart Circ Physiol 2004; 288: 822-828.
23. Langenfeld MR, Simmons LA, McCrohn JA, Raitakari OT, Lattimore J-D, Hennessy A, et al. Nitric oxide does not mediate the vasodilation of early human pregnancy. Heart Lung Circ 2003; 12: 142-148.
24. Lerman A, Zeiher AM. Endothelial function: Cardiac Events. Circulation 2005; 111: 363-368.
25. Heitzer T, Schlingzig T, Krohn K, Meinertz T, Münzel T. Endothelial dysfunction, oxidative stress, and risk for cardiovascular events in patients with coronary artery disease. Circulation 2001; 104: 2673-2678.
26. Vita JA, Keaney JF. Endothelial function: A barometer for cardiovascular risk? Circulation 2002; 106: 640-642.