메뉴 건너뛰기




Volumn 33, Issue 5, 2010, Pages 478-484

Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism

Author keywords

CYP11B1; CYP11B2; PH; Polymorphism

Indexed keywords

ALDOSTERONE SYNTHASE; CYTOCHROME P450; CYTOCHROME P450 CYP11B1; UNCLASSIFIED DRUG;

EID: 77951964892     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2010.21     Document Type: Article
Times cited : (13)

References (26)
  • 4
    • 0035217039 scopus 로고    scopus 로고
    • Juvenile hypertension, the role of genetically altered steroid metabolism
    • Ferrari P, Bianchetti M, Frey FJ. Juvenile hypertension, the role of genetically altered steroid metabolism. Horm Res 2001; 55: 213-223.
    • (2001) Horm Res , vol.55 , pp. 213-223
    • Ferrari, P.1    Bianchetti, M.2    Frey, F.J.3
  • 5
    • 0024842845 scopus 로고
    • Characterization of two genes encoding human steroid 11 beta-hydroxylase (p-450(11) beta)
    • Mornet E, Dupont J, Vitek A, White PC. Characterization of two genes encoding human steroid 11 beta-hydroxylase (p-450(11) beta). J Biol Chem 1989; 264: 20961-20967.
    • (1989) J Biol Chem , vol.264 , pp. 20961-20967
    • Mornet, E.1    Dupont, J.2    Vitek, A.3    White, P.C.4
  • 6
    • 0033034853 scopus 로고    scopus 로고
    • Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene cyp11b2
    • Davies E, Holloway CD, Ingram MC, Inglis GC, Friel EC, Morrison C, Anderson NH, Fraser R, Connell JM. Aldosterone excretion rate and blood pressure in essential hypertension are related to polymorphic differences in the aldosterone synthase gene cyp11b2. Hypertension 1999; 33: 703-707.
    • (1999) Hypertension , vol.33 , pp. 703-707
    • Davies, E.1    Holloway, C.D.2    Ingram, M.C.3    Inglis, G.C.4    Friel, E.C.5    Morrison, C.6    Anderson, N.H.7    Fraser, R.8    Connell, J.M.9
  • 8
    • 0038305903 scopus 로고    scopus 로고
    • A biallelic gene polymorphism of cyp11b2 predicts increased aldosterone to renin ratio in selected hypertensive patients
    • Nicod J, Bruhin D, Auer L, Vogt B, Frey FJ, Ferrari P. A biallelic gene polymorphism of cyp11b2 predicts increased aldosterone to renin ratio in selected hypertensive patients. J Clin Endocrinol Metab 2003; 88: 2495-2500.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2495-2500
    • Nicod, J.1    Bruhin, D.2    Auer, L.3    Vogt, B.4    Frey, F.J.5    Ferrari, P.6
  • 11
    • 0035725546 scopus 로고    scopus 로고
    • Polymorphic differences from normal in the aldosterone synthase gene (cyp11b2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome)
    • Inglis GC, Plouin PF, Friel EC, Davies E, Fraser R, Connell JM. Polymorphic differences from normal in the aldosterone synthase gene (cyp11b2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome). Clin Endocrinol (Oxf) 2001; 54: 725-730.
    • (2001) Clin Endocrinol (Oxf) , vol.54 , pp. 725-730
    • Inglis, G.C.1    Plouin, P.F.2    Friel, E.C.3    Davies, E.4    Fraser, R.5    Connell, J.M.6
  • 14
    • 0031757967 scopus 로고    scopus 로고
    • Diagnosis of glucocorticoid-remediable aldosteronism in primary aldosteronism: Aldosterone response to dexamethasone and long polymerase chain reaction for chimeric gene
    • Mulatero P, Veglio F, Pilon C, Rabbia F, Zocchi C, Limone P, Boscaro M, Sonino N, Fallo F. Diagnosis of glucocorticoid-remediable aldosteronism in primary aldosteronism: aldosterone response to dexamethasone and long polymerase chain reaction for chimeric gene. J Clin Endocrinol Metab 1998; 83: 2573-2575.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2573-2575
    • Mulatero, P.1    Veglio, F.2    Pilon, C.3    Rabbia, F.4    Zocchi, C.5    Limone, P.6    Boscaro, M.7    Sonino, N.8    Fallo, F.9
  • 18
    • 0029020640 scopus 로고
    • Haplotype analysis of cyp11b2
    • White P, Slutsker L. Haplotype analysis of cyp11b2. Endocr Res 1995; 21: 437-442.
    • (1995) Endocr Res , vol.21 , pp. 437-442
    • White, P.1    Slutsker, L.2
  • 20
    • 20044377754 scopus 로고    scopus 로고
    • Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion
    • Keavney B, Mayosi B, Gaukrodger N, Imrie H, Baker M, Fraser R, Ingram M, Watkins H, Farrall M, Davies E, Connell J. Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion. J Clin Endocrinol Metab 2005; 90: 1072-1077.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1072-1077
    • Keavney, B.1    Mayosi, B.2    Gaukrodger, N.3    Imrie, H.4    Baker, M.5    Fraser, R.6    Ingram, M.7    Watkins, H.8    Farrall, M.9    Davies, E.10    Connell, J.11
  • 21
    • 42149174492 scopus 로고    scopus 로고
    • Effect of variation in cyp11b1 and cyp11b2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects
    • Freel EM, Ingram M, Wallace AM, White A, Fraser R, Davies E, Connell JM. Effect of variation in cyp11b1 and cyp11b2 on corticosteroid phenotype and hypothalamic-pituitary-adrenal axis activity in hypertensive and normotensive subjects. Clin Endo-crinol (Oxf) 2008; 68: 700-706.
    • (2008) Clin Endo-crinol (Oxf) , vol.68 , pp. 700-706
    • Freel, E.M.1    Ingram, M.2    Wallace, A.M.3    White, A.4    Fraser, R.5    Davies, E.6    Connell, J.M.7
  • 25
    • 34447547524 scopus 로고    scopus 로고
    • Aldosterone synthase gene T-344C polymorphism, sodium and blood pressure in a free-living population: A community-based study
    • Yamagishi K, Tanigawa T, Cui R, Tabata M, Ikeda A, Yao M, Shimamoto T, Iso H. Aldosterone synthase gene T-344C polymorphism, sodium and blood pressure in a free-living population: a community-based study. Hypertens Res 2007; 30: 497-502.
    • (2007) Hypertens Res , vol.30 , pp. 497-502
    • Yamagishi, K.1    Tanigawa, T.2    Cui, R.3    Tabata, M.4    Ikeda, A.5    Yao, M.6    Shimamoto, T.7    Iso, H.8
  • 26
    • 0043095586 scopus 로고    scopus 로고
    • Haplotype analysis of aldosterone synthase gene (cyp11b2) polymorphisms shows association with essential hypertension
    • Kumar NN, Benjafield AV, Lin RC, Wang WY, Stowasser M, Morris BJ. Haplotype analysis of aldosterone synthase gene (cyp11b2) polymorphisms shows association with essential hypertension. J Hypertens 2003; 21: 1331-1337.
    • (2003) J Hypertens , vol.21 , pp. 1331-1337
    • Kumar, N.N.1    Benjafield, A.V.2    Lin, R.C.3    Wang, W.Y.4    Stowasser, M.5    Morris, B.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.