Thyroid hormone induces artery smooth muscle cell proliferation: Discovery of a new TRα1-Nox1 pathway

Journal of Cellular and Molecular Medicine

Volumn 14, Issue 1-2, 2010, Pages 368-380

  Wang, Xiuqing ^a   Sun, Zhongjie ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

NOX1; Proliferation; ROS; Smooth muscle cell; Thyroid hormone; TR 1

Indexed keywords

CYBB PROTEIN, RAT; CYCLINE; MEMBRANE PROTEIN; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; SMALL INTERFERING RNA; THYROID HORMONE; THYROID HORMONE RECEPTOR ALPHA;

ANIMAL; AORTA; ARTICLE; CELL LINE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; GENETICS; HISTOLOGY; METABOLISM; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; CELL LINE; CELL PROLIFERATION; MEMBRANE GLYCOPROTEINS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NADH, NADPH OXIDOREDUCTASES; NADPH OXIDASE; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONES;

RATTUS;

EID: 77951961043     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2008.00489.x     Document Type: Article

References (50)

1. Kinugawa K, Jeong MY, Bristow MR. Thyroid hormone induces cardiac myocyte hypertrophy in a thyroid hormone receptor alpha1-specific manner that requires TAK1 and p38 mitogen-activated protein kinase. Mol Endocrinol. 2005, 19:1618-28.
2. Fregly MJ, Rossi F, Cade JR. A role for thyroid hormones in cold-induced elevation of blood pressure and cardiac hypertrophy. Can J Physiol Pharmacol. 1994, 72:1066-74.
3. Shohet RV, Kisanuki YY, Zhao XS. Mice with cardiomyocyte-specific disruption of endothelin-1 gene are resistant to hyperthyroid cardiac hypertrophy. Proc Natl Acad Sci USA. 2004, 101:2088-93.
4. Dillmann WH. Biochemical basis of thyroid hormone action in the heart. Am J Med. 1990, 88:626-30.
5. Dillmann WH. Thyroid hormone action and cardiac contractility-a complex affair. Endocrinology. 1996, 137:799-801.
6. Short J, Brown RF, Husakova A. Induction of deoxyribonucleic acid synthesis in the liver of intact animal. J Biol Chem. 1972, 247:1757-66.
7. Francavilla A, Carr BI, Azzarone A. Hepatocyte proliferation and gene expression induced by triiodothyronine in vivo and in vitro. Hepatology. 1994, 20:1237-41.
8. Green S, Kumar V, Theulaz I. The N-terminal DNA-binding 'Zinc finger' of the oestrogen and glucocorticoid receptors determines target gene specificity. EMBO J. 1988, 7:3037-44.
9. Bourguet W, Ruff M, Chambon P. Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha. Nature. 1995, 375:377-82.
10. Lazar MA. Thyroid hormone receptors: multiple forms, multiple possibilities. Endocr Rev. 1993, 14:348-99.
11. Koenig RJ, Lazar MA, Hodin RA. Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing. Nature. 1989, 337:659-61.
12. Wood WM, Dowding JM, Bright TM. Thyroid hormone receptor beta2 promoter activity in pituitary cells is regulated by Pit-1. J Biol Chem. 1996, 271:24213-20.
13. Alkemade A, Vuijst CL, Unmehopa UA. Thyroid hormone receptor expression in the human hypothalamus and anterior pituitary. J Clin Endocrinol Metab. 2005, 90:904-12.
14. Suh YA, Arnold RS, Lassegue B. Cell transformation by the superoxide-generating oxidase MOX1. Nature. 1999, 401:79-82.
15. Banfi B, Clark RA, Steger K. Two novel proteins activate superoxide generation by NADPH oxidase NOX1. J Biol Chem. 2003, 278:510-3.
16. Szanto I, Rubbia-Brandt L, Kiss P. Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease. J Pathol. 2005, 207:164-76.
17. Ago T, Kitazono T, Kuroda J. NAD(P)H oxidases in rat basilar arterial endothelial cells. Stroke. 2005, 36:1040-6.
18. Kobayashi S, Nojima Y, Shibuya M. NOX1 regulates apoptosis and potentially stimulates branching morphogenesis in sinusoidal endothelial cells. Exp Cell Res. 2004, 300:455-62.
19. Griendling KK, Minieri CA, Ollerenshaw JD. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994, 74:1141-8.
20. Zafari AM, Ushio-Fukai M, Akers M. Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy. Hypertension. 1998, 32:488-95.
21. Wolin MS. Activated oxygen metabolites as regulators of vascular tone. Klin Wochenschr. 1991, 69:1046-9.
22. Katsuyama M, Fan C, Yabe-Nishimura C. NADPH oxidase is involved in prostaglandin F2 alpha-induced hypertrophy of vascular smooth muscle cells: induction of NOX1 by PGF2alpha. J Biol Chem. 2002, 277:13438-42.
23. Lassegue B, Sorescu D, Szocs K. Novel gp91(phox) homologues in vascular smooth muscle cells: nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways. Circ Res. 2001, 88:888-94.
24. Katsuyama M, Fan C, Arakawa N. Essential role of ATF-1 in induction of NOX1, a catalytic subunit of NADPH oxidase: involvement of mitochondrial respiratory chain. Biochem J. 2005, 386:255-61.
25. Fan CY, Katsuyama M, Nishinaka T. Transactivation of the EGF receptor and a PI3 kinase-ATF-1 pathway in involved in the upregulation of NOX1, a catalytic subunit of NADPH oxidase. FEBS Lett. 2005, 579:1301-5.
26. Szatrowski TP, Nathan CF. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 1991, 51:794-8.
27. Burdon R. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Rad. Biol Med. 1995, 18:775-94.
28. Xia Y, Zweier JL, Sollott SJ. Mitogenic signalling mediated by oxidants in ras-transfomed fibroblasts. Science. 1997, 275:1649-52.
29. Matsuno K, Yamada H, Iwata K. Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice. Circulation. 2005, 112:2677-85.
30. Wang X, Cade R, Sun Z. Human eNOS gene delivery attenuates cold-induced elevation of blood pressure in rats. Am J Physiol Heart Circ Physiol. 2005, 289:H1161-8.
31. Wang X, Cade R, Sun Z. Expression of human eNOS in cardiac and endothelial cells. Methods Mol Med. 2005, 112:91-107.
32. Zhongjie S, Zhonge Z, Robert C. Renal responses to chronic cold exposure. Can J Physiol Pharmacol. 2003, 81:22-7.
33. Yamomoto N, Sawada H, Izumi Y. Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease. J Biol Chem. 2007, 282:4364-72.
34. Touyz RM, Tabet F, Schiffrin EL. Redox-dependent signaling by angiotensin II and vascular remodeling hypertension. Clin Exp Pharmacol Physiol. 2003, 30:860-6.
35. Nauseef WM. Assembly of the phagocyte NADPH oxidase. Histochem Cell Biol. 2004, 122:277-91.
36. Prelich G, Tan CK, Kostura M. Functional identity of proliferating cell nuclear antigen and DNA polymerase delta auxiliary protein. Nature. 1987, 326:517-20.
37. Bravo R, Frank R, Blundell PA. Cyclin-PCNA is the auxiliary protein of DNA polymerase delta. Nature. 1987, 326:515-7.
38. Madsen P, Celis J. S-phase patterns of cyclin (PCNA) antigen staining resemble topographical patterns of DNA synthesis: a role for cyclin in DNA replication. FEBS Lett. 1985, 193:5-11.
39. Hellstrand P, Albinsson S. Stretch-dependent growth and differentiation in vascular smooth muscle: role of the actin cytoskeleton. Can J Physiol Pharmacol. 2005, 83:869-75.
40. Thyberg J. Differentiated properties and proliferation of arterial smooth muscle cells in culture. Int Rev Cytol. 1996, 169:183-265.
41. Michienzi S, Bucci B, Verga Falzacappa C. 3,3',5-Triiodo-L-thyronine inhibits ductal pancreatic adenocarcinoma proliferation improving the cytotoxic effect of chemotherapy. J Endocrinol. 2007, 193:209-23.
42. Chattergoon NN, Giraud GD, Thornburg KL. Thyroid hormone inhibits proliferation of fetal cardiac myocytes in vitro. J Endocrinol. 2007, 192:R1-8.
43. Kasahara T, Tsunekawa K, Seki K. Regulation of iodothyronine deiodinase and roles of thyroid hormones in human coronary artery smooth muscle cells. Atherosclerosis. 2006, 186:207-14.
44. Fukuyama K, Ichiki T, Imayama I. Thyroid hormone inhibits vascular remodeling through suppression of cAMP response element binding protein activity. Arterioscler Thromb Vasc Biol. 2006, 26:2049-55.
45. Lin HY, Tang HY, Shih A. Thyroid hormone is a MAPK-dependent growth factor for thyroid cancer cells and is anti-apoptotic. Steroids. 2007, 72:180-7.
46. Ledda-Columbano GM, Perra A, Pibiri M. Induction of pancreatic acinar cell proliferation by thyroid hormone. J Endocrinol. 2005, 185:393-9.
47. Chamulitrat W, Schmidt R, Tomakidi P. Association of gp91phox homolog Nox1 with anchorage-independent growth and MAP kinase-activation of transformed human keratinocytes. Oncogene. 2003, 22:6045-53.
48. Janiszewski M, Lopes LR, Carmo AO. Regulation of NAD(P)H oxidase by associated protein disulfide isomerase in vascular smooth muscle cells. J Biol Chem. 2005, 280:40813-19.
49. Hilenski LL, Clempus RE, Quinn MT. Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2004, 24:677-83.
50. Hanna IR, Hilenski LL, Dikalova A. Functional association of nox1 with p22phox in vascular smooth muscle cells. Free Radic Biol Med. 2004, 37:1542-9.