Quinolinate phosphoribosyl transferase, a key enzyme in de novo NAD+ synthesis, suppresses spontaneous cell death by inhibiting overproduction of active-caspase-3

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1803, Issue 5, 2010, Pages 527-533

  Ishidoh, Kazumi ^a   Kamemura, Norio ^a   Imagawa, Takahito ^a   Oda, Masataka ^a   Sakurai, Jun ^a   Katunuma, Nobuhiko ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

Active caspase 3; NAD+ synthesis; Quinolinate phosphoribosyl transferase; Spontaneous cell death

Indexed keywords

CASPASE 3; DACTINOMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; QUINOLINATE PHOSPHORIBOSYL TRANSFERASE; RECOMBINANT PROTEIN; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE; UPREGULATION; ZYMOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CATTLE; CELL SURVIVAL; CELLS, CULTURED; CYTOPLASM; DACTINOMYCIN; ENZYME ACTIVATION; HELA CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; LIVER; MOLECULAR SEQUENCE DATA; NAD; PENTOSYLTRANSFERASES; RECOMBINANT PROTEINS;

EID: 77951939034     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2010.02.007     Document Type: Article

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