Design, synthesis and biological evaluation of novel spin-labeled derivatives of podophyllotoxin

Natural Product Communications

Volumn 5, Issue 2, 2010, Pages 241-244

  Zhang, Jia Qiang ^a   Zhang, Zhi Wei ^a   Hui, Ling ^b   Tian, Xuan ^a  

^a LANZHOU UNIVERSITY   (China)

^b LANZHOU GENERAL HOSPITAL   (China)

Author keywords

Antioxidant; Antitumor; Nitroxides; Podophyllotoxin

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; ETOPOSIDE; MALONALDEHYDE; N (1' OXYL 3' CARBOXYL 2',2',5',5 TETRAMETHYLPYRROLINE) METHIONINE 4 BETA AMIDE 4' DEMETHYLEPIPODOPHYLLOTOXIN ACYLAMIDE; N (1' OXYL 3' CARBOXYL 2',2',5',5 TETRAMETHYLPYRROLINE) PROLINE 4 BETA AMIDE 4' DEMETHYLEPIPODOPHYLLOTOXIN ACYLAMIDE; N (1' OXYL 3' CARBOXYL 2',2',5',5' TETRAMETHYL PYRROLINE) GLYCINE 4 BETA AMIDE 4' DEMETHYLEPIPODOPHYLLOTOXIN ACYLAMIDE; N (1' OXYL 3' CARBOXYL 2',2',5',5' TETRAMETHYLPYRROLINE) ALANINE 4 BETA AMIDE 4' DEMETHYLEPIPODOPHYLLOTOXIN ACYLAMIDE; N (1' OXYL 3' CARBOXYL 2',2',5',5' TETRAMETHYLPYRROLINE) PHENYLALANINE 4 BETA AMIDE 4' DEMETHYLEPIPODOPHYLLOTOXIN ACYLAMIDE; PODOPHYLLOTOXIN DERIVATIVE; UNCLASSIFIED DRUG; PODOPHYLLOTOXIN;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER INHIBITION; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY HOMOGENATE; LIVER HOMOGENATE; LUNG CARCINOMA; MULTIPLE MYELOMA; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PARTITION COEFFICIENT; RAT; SPIN LABELING; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM;

RATTUS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MOLECULAR STRUCTURE; PODOPHYLLOTOXIN;

EID: 77951927574     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1000500214     Document Type: Article

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