메뉴 건너뛰기




Volumn 29, Issue 17, 2010, Pages 2550-2559

PI4KIIα is a novel regulator of tumor growth by its action on angiogenesis and HIF-1α regulation

Author keywords

Phosphatidylinositol 4 kinase type IIa (PI4KIIa); tumor; angiogenesis; hypoxia inducible factor 1a (HIF 1 )

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL KINASE; PHOSPHATIDYLINOSITOL KINASE 2ALPHA; UNCLASSIFIED DRUG; HIF1A PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL PHOSPHATE 4 KINASE; PHOSPHATIDYLINOSITOL PHOSPHATE 4-KINASE; PHOSPHOTRANSFERASE;

EID: 77951879261     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.14     Document Type: Article
Times cited : (47)

References (41)
  • 1
    • 44949264001 scopus 로고    scopus 로고
    • Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic
    • Craige B, Salazar G, Faundez V. (2008). Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic. Mol Biol Cell 19: 1415-1426.
    • (2008) Mol Biol Cell , vol.19 , pp. 1415-1426
    • Craige, B.1    Salazar, G.2    Faundez, V.3
  • 2
    • 33749836234 scopus 로고    scopus 로고
    • Phosphoinositides in cell regulation and membrane dynamics
    • Di PG, De CP. (2006). Phosphoinositides in cell regulation and membrane dynamics. Nature 443: 651-657.
    • (2006) Nature , vol.443 , pp. 651-657
    • Di, P.G.1    De, C.P.2
  • 3
    • 57349153078 scopus 로고
    • The standardization of hemoglobin measurement
    • Drabkin D. (1949). The standardization of hemoglobin measurement. Am J Med Sci 217: 710-711.
    • (1949) Am J Med Sci , vol.217 , pp. 710-711
    • Drabkin, D.1
  • 4
    • 0036782278 scopus 로고    scopus 로고
    • VEGF and the quest for tumour angiogenesis factors
    • Ferrara N. (2002). VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2: 795-803.
    • (2002) Nat Rev Cancer , vol.2 , pp. 795-803
    • Ferrara, N.1
  • 5
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. (1971). Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 6
    • 0019133502 scopus 로고
    • Angiogenesis in vitro
    • Folkman J, Haudenschild C. (1980). Angiogenesis in vitro. Nature 288: 551-556.
    • (1980) Nature , vol.288 , pp. 551-556
    • Folkman, J.1    Haudenschild, C.2
  • 7
    • 0032521870 scopus 로고    scopus 로고
    • Is there a role for nitric oxide in tumor angiogenesis?
    • Garcia-Cardena G, Folkman J. (1998). Is there a role for nitric oxide in tumor angiogenesis? J Natl Cancer Inst 90: 560-561.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 560-561
    • Garcia-Cardena, G.1    Folkman, J.2
  • 9
    • 67651148274 scopus 로고    scopus 로고
    • Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling
    • Gewinner C, Wang ZC, Richardson A, Teruya-Feldstein J, Etemad-moghadam D, Bowtell D et al. (2009). Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling. Cancer Cell 16: 115-125.
    • (2009) Cancer Cell , vol.16 , pp. 115-125
    • Gewinner, C.1    Wang, Z.C.2    Richardson, A.3    Teruya-Feldstein, J.4    Etemad-Moghadam, D.5    Bowtell, D.6
  • 10
    • 0026470956 scopus 로고
    • Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo
    • Grant DS, Kinsella JL, Fridman R, Auerbach R, Piasecki BA, Yamada Y et al. (1992). Interaction of endothelial cells with a laminin A chain peptide (SIKVAV) in vitro and induction of angiogenic behavior in vivo. J Cell Physiol 153: 614-625.
    • (1992) J Cell Physiol , vol.153 , pp. 614-625
    • Grant, D.S.1    Kinsella, J.L.2    Fridman, R.3    Auerbach, R.4    Piasecki, B.A.5    Yamada, Y.6
  • 11
    • 0037386564 scopus 로고    scopus 로고
    • Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles
    • Guo J, Wenk MR, Pellegrini L, Onofri F, Benfenati F, De CP. (2003). Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles. Proc Natl Acad Sci USA 100: 3995-4000.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3995-4000
    • Guo, J.1    Wenk, M.R.2    Pellegrini, L.3    Onofri, F.4    Benfenati, F.5
  • 12
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J. (1996). Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 14
    • 0033181324 scopus 로고    scopus 로고
    • Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1
    • Hellwig-Burgel T, Rutkowski K, Metzen E, Fandrey J, Jelkmann W. (1999). Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1. Blood 94: 1561-1567.
    • (1999) Blood , vol.94 , pp. 1561-1567
    • Hellwig-Burgel, T.1    Rutkowski, K.2    Metzen, E.3    Fandrey, J.4    Jelkmann, W.5
  • 15
    • 0027818333 scopus 로고
    • Oncogene regulation by growth factors
    • Hsuan JJ. (1993). Oncogene regulation by growth factors. Anticancer Res 13: 2521-2532.
    • (1993) Anticancer Res , vol.13 , pp. 2521-2532
    • Hsuan, J.J.1
  • 16
    • 0037490210 scopus 로고    scopus 로고
    • Hypoxia-inducible factor and its biomedical relevance
    • Huang LE, Bunn HF. (2003). Hypoxia-inducible factor and its biomedical relevance. J Biol Chem 278: 19575-19578.
    • (2003) J Biol Chem , vol.278 , pp. 19575-19578
    • Huang, L.E.1    Bunn, H.F.2
  • 17
    • 0030787469 scopus 로고    scopus 로고
    • Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension
    • Jiang BH, Zheng JZ, Leung SW, Roe R, Semenza GL. (1997). Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension. J Biol Chem 272: 19253-19260.
    • (1997) J Biol Chem , vol.272 , pp. 19253-19260
    • Jiang, B.H.1    Zheng, J.Z.2    Leung, S.W.3    Roe, R.4    Semenza, G.L.5
  • 18
    • 0027973076 scopus 로고
    • Regulation of human type II phosphatidylinositol kinase activity by epidermal growth factor-dependent phosphorylation and receptor association
    • Kauffmann-Zeh A, Klinger R, Kauffmann-Zeh A, Endemann G, Waterfield MD, Wetzker R et al. (1994). Regulation of human type II phosphatidylinositol kinase activity by epidermal growth factor-dependent phosphorylation and receptor association. J Biol Chem 269: 31243-31251.
    • (1994) J Biol Chem , vol.269 , pp. 31243-31251
    • Kauffmann-Zeh, A.1    Klinger, R.2    Kauffmann-Zeh, A.3    Endemann, G.4    Waterfield, M.D.5    Wetzker, R.6
  • 19
    • 0142056101 scopus 로고    scopus 로고
    • The Wnt signaling pathway in solid childhood tumors
    • Koesters R, von Knebel DM. (2003). The Wnt signaling pathway in solid childhood tumors. Cancer Lett 198: 123-138.
    • (2003) Cancer Lett , vol.198 , pp. 123-138
    • Koesters, R.1    Von Knebel, D.M.2
  • 20
    • 0024094113 scopus 로고
    • Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures
    • Kubota Y, Kleinman HK, Martin GR, Lawley TJ. (1988). Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures. J Cell Biol 107: 1589-1598.
    • (1988) J Cell Biol , vol.107 , pp. 1589-1598
    • Kubota, Y.1    Kleinman, H.K.2    Martin, G.R.3    Lawley, T.J.4
  • 21
    • 0034529914 scopus 로고    scopus 로고
    • Suppression of tumor growth through disruption of hypoxia-inducible transcription
    • Kung AL, Wang S, Klco JM, Kaelin WG, Livingston DM. (2000). Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med 6: 1335-1340.
    • (2000) Nat Med , vol.6 , pp. 1335-1340
    • Kung, A.L.1    Wang, S.2    Klco, J.M.3    Kaelin, W.G.4    Livingston, D.M.5
  • 22
    • 1642387020 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF-1)alpha: Its protein stability and biological functions
    • Lee JW, Bae SH, Jeong JW, Kim SH, Kim KW. (2004). Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions. Exp Mol Med 36: 1-12.
    • (2004) Exp Mol Med , vol.36 , pp. 1-12
    • Lee, J.W.1    Bae, S.H.2    Jeong, J.W.3    Kim, S.H.4    Kim, K.W.5
  • 23
    • 0028786601 scopus 로고
    • A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
    • Melillo G, Musso T, Sica A, Taylor LS, Cox GW, Varesio L. (1995). A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Exp Med 182: 1683-1693.
    • (1995) J Exp Med , vol.182 , pp. 1683-1693
    • Melillo, G.1    Musso, T.2    Sica, A.3    Taylor, L.S.4    Cox, G.W.5    Varesio, L.6
  • 24
    • 0035907368 scopus 로고    scopus 로고
    • Cloning of a human type ii phosphatidy-linositol 4-kinase reveals a novel lipid kinase family
    • Minogue S, Anderson JS, Waugh MG, dos Santos M, Corless S, Cramer R et al. (2001). Cloning of a human type ii phosphatidy-linositol 4-kinase reveals a novel lipid kinase family. J Biol Chem 276: 16635-16640.
    • (2001) J Biol Chem , vol.276 , pp. 16635-16640
    • Minogue, S.1    Anderson, J.S.2    Waugh, M.G.3    Dos Santos, M.4    Corless, S.5    Cramer, R.6
  • 25
    • 33644989853 scopus 로고    scopus 로고
    • Phosphatidylinositol 4-kinase is required for endosomal trafficking and degradation of the EGF receptor
    • Minogue S, Waugh MG, De Matteis MA, Stephens DJ, Berditchevski F, Hsuan JJ. (2006). Phosphatidylinositol 4-kinase is required for endosomal trafficking and degradation of the EGF receptor. J Cell Sci 119: 571-581.
    • (2006) J Cell Sci , vol.119 , pp. 571-581
    • Minogue, S.1    Waugh, M.G.2    De Matteis, M.A.3    Stephens, D.J.4    Berditchevski, F.5    Hsuan, J.J.6
  • 26
    • 51149123490 scopus 로고    scopus 로고
    • Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation
    • Pan W, Choi SC, Wang H, Qin Y, Volpicelli-Daley L, Swan L et al. (2008). Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation. Science 321: 1350-1353.
    • (2008) Science , vol.321 , pp. 1350-1353
    • Pan, W.1    Choi, S.C.2    Wang, H.3    Qin, Y.4    Volpicelli-Daley, L.5    Swan, L.6
  • 27
    • 69249147832 scopus 로고    scopus 로고
    • Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl2
    • Qin Y, Li L, Pan W, Wu D. (2009). Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl2. J Biol Chem 284: 22544-22548.
    • (2009) J Biol Chem , vol.284 , pp. 22544-22548
    • Qin, Y.1    Li, L.2    Pan, W.3    Wu, D.4
  • 28
    • 2442701289 scopus 로고    scopus 로고
    • The ErbB/HER receptor protein-tyrosine kinases and cancer
    • Roskoski Jr R. (2004). The ErbB/HER receptor protein-tyrosine kinases and cancer. Biochem Biophys Res Commun 319: 1-11.
    • (2004) Biochem Biophys Res Commun , vol.319 , pp. 1-11
    • Roskoski Jr., R.1
  • 29
    • 59449092912 scopus 로고    scopus 로고
    • Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells
    • Salazar G, Zlatic S, Craige B, Peden AA, Pohl J, Faundez V. (2009). Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells. J Biol Chem 284: 1790-1802.
    • (2009) J Biol Chem , vol.284 , pp. 1790-1802
    • Salazar, G.1    Zlatic, S.2    Craige, B.3    Peden, A.A.4    Pohl, J.5    Faundez, V.6
  • 31
    • 0034901463 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
    • Semenza GL. (2001). Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends Mol Med 7: 345-350.
    • (2001) Trends Mol Med , vol.7 , pp. 345-350
    • Semenza, G.L.1
  • 32
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • Semenza GL. (2002). HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol Med 8: S62-S67.
    • (2002) Trends Mol Med , vol.8
    • Semenza, G.L.1
  • 33
    • 67650866728 scopus 로고    scopus 로고
    • Loss of phosphatidylinositol 4-kinase 2alpha activity causes late onset degeneration of spinal cord axons
    • Simons JP, Al-Shawi R, Minogue S, Waugh MG, Wiedemann C, Evangelou S et al. (2009). Loss of phosphatidylinositol 4-kinase 2alpha activity causes late onset degeneration of spinal cord axons. Proc Natl Acad Sci USA 106: 11535-11539.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11535-11539
    • Simons, J.P.1    Al-Shawi, R.2    Minogue, S.3    Waugh, M.G.4    Wiedemann, C.5    Evangelou, S.6
  • 35
    • 0037008770 scopus 로고    scopus 로고
    • Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
    • Treins C, Giorgetti-Peraldi S, Murdaca J, Semenza GL, Van OE. (2002). Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway. J Biol Chem 277: 27975-27981.
    • (2002) J Biol Chem , vol.277 , pp. 27975-27981
    • Treins, C.1    Giorgetti-Peraldi, S.2    Murdaca, J.3    Semenza, G.L.4    Van, O.E.5
  • 36
    • 0042591490 scopus 로고    scopus 로고
    • Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi
    • Wang YJ, Wang J, Sun HQ, Martinez M, Sun YX, Macia E et al. (2003). Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. Cell 114: 299-310.
    • (2003) Cell , vol.114 , pp. 299-310
    • Wang, Y.J.1    Wang, J.2    Sun, H.Q.3    Martinez, M.4    Sun, Y.X.5    MacIa, E.6
  • 37
    • 0038343926 scopus 로고    scopus 로고
    • Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/valosin-containing-protein-rich fraction of the endoplasmic reticulum
    • Waugh MG, Minogue S, Anderson JS, Balinger A, Blumenkrantz D, Calnan DP et al. (2003). Localization of a highly active pool of type II phosphatidylinositol 4-kinase in a p97/valosin-containing-protein-rich fraction of the endoplasmic reticulum. Biochem J 373: 57-63.
    • (2003) Biochem J , vol.373 , pp. 57-63
    • Waugh, M.G.1    Minogue, S.2    Anderson, J.S.3    Balinger, A.4    Blumenkrantz, D.5    Calnan, D.P.6
  • 39
    • 33751503041 scopus 로고    scopus 로고
    • Phosphatidylinositol 4-kinase type IIalpha is targeted specifically to cellugyrin-positive glucose transporter 4 vesicles
    • Xu Z, Huang G, Kandror KV. (2006). Phosphatidylinositol 4-kinase type IIalpha is targeted specifically to cellugyrin-positive glucose transporter 4 vesicles. Mol Endocrinol 20: 2890-2897.
    • (2006) Mol Endocrinol , vol.20 , pp. 2890-2897
    • Xu, Z.1    Huang, G.2    Kandror, K.V.3
  • 40
    • 14744283538 scopus 로고    scopus 로고
    • Expression level of valosin-containing protein (p97) is correlated with progression and prognosis of non-small-cell lung carcinoma
    • DOI 10.1245/ASO.2004.10.018
    • Yamamoto S, Tomita Y, Hoshida Y, Iizuka N, Monden M, Yamamoto S et al. (2004). Expression level of valosin-containing protein (p97) is correlated with progression and prognosis of non-small-cell lung carcinoma. Ann Surg Oncol 11: 697-704. (Pubitemid 40486705)
    • (2004) Annals of Surgical Oncology , vol.11 , Issue.7 , pp. 697-704
    • Yamamoto, S.1    Tomita, Y.2    Hoshida, Y.3    Iizuka, N.4    Monden, M.5    Yamamoto, S.6    Iuchi, K.7    Aozasa, K.8
  • 41
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM et al. (2000). Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 60: 1541-1545.
    • (2000) Cancer Res , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.