Development of a high-throughput screening platform for DNA 3′-phosphatases and their inhibitors based on a universal molecular beacon and quantitative real-time PCR

Chemistry - An Asian Journal

Volumn 5, Issue 5, 2010, Pages 1146-1151

  Song, Chen ^a   Zhang, Chen ^a   Zhao, Mei Ping ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

DNA; Fluorescent probes; High throughput screening; Inhibitors; Polymerase chain reaction

Indexed keywords

ALKALINE PHOSPHATASE; DETECTION PROCESS; DNA DAMAGING AGENTS; EFFICIENT DETECTION; FLUORESCENT PROBES; HIGH-THROUGHPUT; HIGH-THROUGHPUT SCREENING; INHIBITION EFFECT; INHIBITORS; MOLECULAR BEACON; POLYNUCLEOTIDES; PRECISE MEASUREMENTS; QUANTITATIVE REAL TIME PCR; RAPID SCREENING; STRAND BREAKS; TEMPLATE SUBSTRATES;

DNA; FLUORESCENCE; GENES; IONIZING RADIATION; NUCLEIC ACIDS; PHOSPHATASES; POLYMERIZATION; PROBES; THROUGHPUT;

POLYMERASE CHAIN REACTION;

ALKALINE PHOSPHATASE; DEOXYNUCLEOTIDE 3' PHOSPHATASE; DEOXYNUCLEOTIDE 3'-PHOSPHATASE; DNA; ENZYME INHIBITOR; FLUORESCENT DYE; HEPARIN; NUCLEOTIDASE; THEOPHYLLINE;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; HIGH THROUGHPUT SCREENING; KINETICS; METABOLISM; POLYMERASE CHAIN REACTION;

ALKALINE PHOSPHATASE; DNA; ENZYME INHIBITORS; FLUORESCENT DYES; HEPARIN; HIGH-THROUGHPUT SCREENING ASSAYS; KINETICS; NUCLEOTIDASES; POLYMERASE CHAIN REACTION; THEOPHYLLINE;

EID: 77951829107     PISSN: 18614728     EISSN: 1861471X     Source Type: Journal    
DOI: 10.1002/asia.200900661     Document Type: Article

References (49)

1. a) W. D. Henner, L. O. Rodriguez, S. M. Hecht, W. A. Haseltine, J. Biol. Chem. 1983, 258, 711 -713
2. b) B. N. Ames, L. S. Gold, W. C. Willett, Proc. Natl. Acad. Sci. USA 1995, 92, 5258-5265.
3. a) F. Karimi-Busheri, J. Lee, A. E. Tomkinson, M. Weinfeld, Nucleic Acid Res. 1998, 26, 4395 - 4400
4. b) W. D. Henner, S. M. Grunberg, W. A. Haseltine, J. Biol. Chem. 1983, 258, 15 198 -15 205
5. c) S. W. Yang, A. B. Burgin, Jr., B. N. Huizenga, C. A. Robertson, K. C. Yao, H. A. Nash, Proc. Natl. Acad. Sci. USA 1996, 93, 11534-11539.
6. a) V. Cameron, O. C. Uhlenbeck, Biochemistry 1977, 16, 5120 -5126
7. b) F. Karimi-Busheri, G. Daly, P. Robins, B. Canas, D. J. C. Pappin, J. Sgouros, G. G. Miller, H. Fakhrai, E. M. Davis, M. M. Le Beau, M. Weinfeld, J. Biol. Chem. 1999, 274, 24187-24194.
8. a) T. A. Winters, W. D. Henner, P. S. Russell, A. McCullough, T. J. Jorgensen, Nucleic Acid Res. 1994, 22, 1866 - 1873
9. b) D. Suh, D. M. Wilson, L. F. Povirk, Nucleic Acid Res. 1997, 25, 2495 - 2500
10. c) L. Wiederhold, J. B. Leppard, P. Kedar, F. Karimi-Busheri, A. Rasouli-Nia, M. Weinfeld, A. E. Tomkinson, T. Izumi, R. Prasad, S. H. Wilson, S. Mitra, T. K. Hazra, Mol. Cell 2004, 15, 209-220.
11. H. K. Misra, N. N. Khan, S. Agrawall, G. E. Wright, Nucleic Acid Res. 1992, 20, 4547-4551.
12. a) Y. Habraken, W. G. Verly, Eur. J. Biochem. 1988, 171, 59 -66
13. b) K. Nogimori, P. J. Hughes, M. C. Glennon, M. E. Hodgson, J. J. Putney, S. B. Shears, J. Biol. Chem. 1991, 266, 16 499 - 16506
14. c) K. M. Holtz, B. Stec, E. R. Kantrowitz, J. Biol. Chem. 1999, 274, 8351 - 8354
15. d) J. G. Zalatan, T. D. Fenn, A. T. Brunger, D. Herschlag, Biochemistry 2006, 45, 9788-9803.
16. a) A. Jilani, D. Ramotar, Biochemistry 2002, 41, 7688 -7694
17. b) H. Zhu, S. M. Yin, S. Shuman, J. Biol. Chem. 2004, 279, 26358 -26369
18. c) T. Takahashi, M. Tada, Nucleic Acid Res. 2007, 35, 3797-3809.
19. a) P. J. O'Brien, D. Herschlag, Biochemistry 2002, 41, 3207 -3225
20. b) T. S. De Souza Malaspina, C. X. Dos Santos, A. P. Campanelli, F. R. M. Laurindo, M. C. Sogayar, J. M. Granjeiro, J. Mol. Histol. 2008, 39, 627-634.
21. a) M. Fanta, H. Zhang, N. Bernstein, M. Glover, F. Karimi-Busheri, M. Weinfeld, Hybridoma 2001, 20, 237 - 242
22. b) F. Karimi-Busheri, A. Rasouli-Nia, J. Allalunis-Turner, M. Weinfeld, Cancer Res. 2007, 67, 6619-6625.
23. a) A. Rasouli-Nia, F. Karimi-Busheri, M. Weinfeld, Proc. Natl. Acad. Sci. USA 2004, 101, 6905 -6910
24. b) A. Jilani, D. Ramotar, C. Slack, C. Ong, X. M. Yang, S. W. Scherer, D. D. Lasko, J. Biol. Chem. 1999, 274, 24176 -24186
25. c) L. K. Wang, S. Shuman, J. Biol. Chem. 2001, 276, 26868-26874.
26. C. L. Dobson, S. L. Allinson, Nucleic Acids Res. 2006, 34, 2230-2237.
27. C. Ma, Z. Tang, K. Wang, W. Tan, X. Yang, W. Li, Z. Li, H. Li, X. Lv, ChemBioChem 2007, 8, 1487-1490.
28. A. K. Chen, M. A. Behlke, A. Tsourkas, Nucleic Acids Res. 2007, 35, e105.
29. X. M. Li, Y. Huang, Y. Guan, M. P. Zhao, Y. Z. Li, Anal. Chem. 2006, 78, 7886-7890.
30. X. M. Li, Y. Huang, C. Song, M. P. Zhao, Y. Z. Li, Anal. Bioanal. Chem. 2007, 388, 979-985.
31. X. M. Li, C. Song, M. P. Zhao, Y. Z. Li, Anal. Biochem. 2008, 381, 1-7.
32. C. C. Richardson, Pro. Natl. Acad. Sci. USA 1965, 541, 58-165.
33. a) E. A. Galburt, J. Pelletier, G. Wilson, B. L. Stoddard, Structure 2002, 10, 1249 -1260
34. b) C. Chappell, L. A. Hanakahi, F. Karimi- Busheri, M. Weinfeld, S. C. West, Embo J. 2002, 21, 2827-2832.
35. a) M. El Atifi, I. Dupre, B. Rostaing, A. L. Benabid, F. Berger, Biotechniques 2003, 35, 262 -266
36. b) C. Frauendorf, F. Hausch, I. Rohl, A. Lichte, S. Vonhoff, S. Klussmann, Nucleic Acids Res. 2003, 31, 34e
37. c) C. K. Lee, B. G. Brown, B. R. Bombick, D. J. Doolittle, Anal. Biochem. 1995, 227, 156 -161
38. d) D. H. Phillips, V. M. Arlt, Nat. Protoc. 2007, 2, 2772-2781.
39. M. Eguchi, Comp. Biochem. Physiol. 1995, 111B, 151-162.
40. R. B. McComb, G. N. Bowers, S. Posen, Alkaline Phosphatase, Plenum Press, New York, 1979.
41. a) J. R. Lillehaug, K. Kleppe, Biochemistry 1975, 14, 1221 - 1225
42. b) J. R. Lillehaug, R. K. Kleppe, K. Kleppe, Biochemistry 1976, 15, 1858 - 1865
43. c) C. Song, M. P. Zhao, Anal. Chem. 2009, 81, 1383-1388.
44. L. R. DeChatelet, C. E. McCall, M. R. Cooper, P. S. Shirley, Clin. Chem. 1972, 18, 1532-1534.
45. a) R. Vassallo, J. J. Lipsky, Mayo Clin. Proc. 1998, 73, 346 -354
46. b) C. P. Page, J. Clin. Pharmacol. 1999, 39, 237 -240
47. c) A. Markham, D. Faulds, Drugs 1998, 56, 1081-1091.
48. a) L. Debthune, G. Kohlhagen, A. Grandas, Y. Pommier, Nucleic Acids Res. 2002, 30, 1198 -1204
49. b) A. C. Raymond, B. L. Staker, A. B. Burgin, Jr., J. Biol. Chem. 2005, 280, 22029-22035.