Potential roles of Cdk5/p35 and tau protein in hippocampal mossy fiber sprouting in the PTZ kindling model

Clinical Laboratory

Volumn 56, Issue 3-4, 2010, Pages 127-136

  Tian, Fa Fa ^a   Zeng, Chang ^a   Ma, Yun Feng ^a,b   Guo, Ting Hui ^a,c   Chen, Jin Mei ^a,d   Chen, Ying ^a,e   Cai, Xiao Feng ^a   Li, Feng Rong ^a   Wang, Xin Hua ^a   Huang, Wen Jiao ^a   Wang, Yu Zhong ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Sanbofuxing Brain Hospital   (China)

^c FUJIAN MEDICAL UNIVERSITY   (China)

^d Putuo People's Hospital ^*  (China)

^e Department of Neurology   (China)

Author keywords

Cyclin dependent kinase 5; Hippocampus; Mossy fiber sprouting; Pentylenetetrazole; Tau protein; Temporal lobe epilepsy

Indexed keywords

CYCLIN DEPENDENT KINASE 5; PENTETRAZOLE; PROTEIN P35; SODIUM CHLORIDE; TAU PROTEIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; LIQUID SCINTILLATION COUNTING; MALE; MICROTUBULE; NERVE FIBER; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SEIZURE; WESTERN BLOTTING;

ANIMALS; CYCLIN-DEPENDENT KINASE 5; DISEASE PROGRESSION; EPILEPSY, TEMPORAL LOBE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INJECTIONS, INTRAPERITONEAL; KINDLING, NEUROLOGIC; MALE; NERVE FIBERS; PENTYLENETETRAZOLE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; TAU PROTEINS;

RATTUS;

EID: 77951799645     PISSN: 14336510     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Matsushita M, Tomizawa K, Lu YF, et al. Distinct cellular compartment of cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activator protein (p35nck5a) in the developing rat cerebellum. Brain Res 1996; 734(1-2): 319-322 (Pubitemid 26334061)
2. Sen A, Thom M, Martinian L, et al. Deregulation of cdk5 in hippocampal sclerosis. J Neuropathol Exp Neurol 2006; 65(1): 55-66.
3. Dhavan R, Tsai LH. A decade of CDK5. Nat Rev Mol Cell Biol 2001; 2: 749-759
4. Zheng M, Leung CL, Liem RK. Region-specific expression of cyclin-dependent kinase 5 (cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous system. J Neurobiol 1998; 35(2): 141-159 (Pubitemid 28178324)
5. Tomizawa K, Cai XH, Moriwaki A, et al. Involvement of Cyclin-Dependent Kinase 5/p35nck5a in the Synaptic Reorganization of Rat Hippocampus during Kindling Progression. Jpn J Physiol 2000; 50(5): 525-532 (Pubitemid 32010153)
6. Avila J, Lucas JJ, Perez M. Role of tau protein in both physiological and pathological conditions. Physiol Rev 2004; 84(2): 361-384 (Pubitemid 38365487)
7. Hashiguchi M, Saito T, Hisanaga S, et al. Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau. J Biol Chem 2002; 277: 44525-44530 (Pubitemid 36157887)
8. Lamont SR, Stanwell BJ, Hill R. Ketamine pre-treatment dissociates the effects of electroconvulsive stimulation on mossy fibre sprouting and cellular proliferation in the dentate gyrus. Brain Res 2005; 1053(1-2): 27-32. (Pubitemid 41116787)
9. Chen J, Zhang Y, Kelz MB, et al. Induction of cyclin-dependent kinase 5 in the hippocampus by chronic electroconvulsive seizures: role of ΔFosB. J Neurosci 2000; 20(24): 8965-8971 (Pubitemid 32042896)
10. Pavlova T, Stepanichev M, Gulyaeva N. Pentylenetetrazole kindling induces neuronal cyclin B1 expression in rat hippocampus. Neurosci Lett 2006; 392(1-2): 154-158 (Pubitemid 41757594)
11. Cavazos JE, Golarai G, Sutula TP. Mossy fiber synaptic reorganization induced by kindling: time course of development, progression, and permanence. J Neurosci 1991; 11: 2795-2803
12. Tian FF, Guo TH, Chen JM, et al. Hippocampal mossy fiber sprouting and Cdk5/p35 expressions in the pentylenetetrazole kindling rat model. J Cent South Univ (Med Sci) 2008; 33(12): 1101-1107
13. Nikolic M, Dudek H, Kwon YT, et al. The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes Dev 1996; 10: 816-825 (Pubitemid 26114738)
14. Cicero S, Herrup K. Cyclin-Dependent Kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci 2005; 25(42): 9658-9668 (Pubitemid 41510906)
15. Zhu YS, Saito T, Asada A, et al. Activation of latent cyclin-dependent kinase 5 (Cdk5)-p35 complexes by membrane dissociation. J Neurochem 2005, 94(6): 1535-1545
16. Jung ME, Lal H, Gatch MB. The discriminative stimulus effects of pentylenetetrazol as a model of anxiety: recent developments. Neurosci Biobehav Rev 2002, 26(4): 429-439 (Pubitemid 36158661)
17. Mathern GW, Cifuentes F, Leite JP, et al. Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model. Electroencephalogr Clin Neurophysiol 1993; 87(5): 326-339 (Pubitemid 23328867)
18. Nissinen J, Lukasiuk K, Pitkanen A. Is mossy fiber sprouting present at the time of the first spontaneous seizures in rat experimental temporal lobe epilepsy? Hippocampus 2001; 11: 299-310.
19. Gorter JA, van Vliet EA, Aronica E, et al. Progression of spontaneous seizures after status epilepticus is associated with mossy fibre sprouting and extensive bilateral loss of hilar parvalbumin and somatostatin-immunoreactive neurons. Eur J Neurosci 2001; 13(4): 657-669 (Pubitemid 32174791)
20. Longo BM, MeIIo LE. Effect of long-term spontaneous recurrent seizures or reinduction of status epilepticus on the development of supragranular mossy fiber sprouting. Epilepsy Res 1999; 36(2-3): 233-241
21. Pierce JP, Melton J, Punsoni M, et al. Mossy fibers are the primary source of afferent input to ectopic granule cells that are born after pilocarpine-induced seizures. Exp Neurol 2005; 196 (2): 316-331 (Pubitemid 41607820)
22. Holmes GL, Sarkisian M, Ben-Ari Y, et al. Mossy fiber sprouting after recurrent seizures during early development in rats. J Comp Neurol 1999; 404: 537-553 (Pubitemid 29084640)
23. Cross DJ, Cavazos JE. Synaptic reorganization in subiculum and CA3 after early-life status epilepticus in the kainic acid rat model. Epilepsy Res 2007; 73(2): 156-165