Quantitative high-performance liquid chromatography-electrospray ionization tandem mass spectrometry analysis of bis- n 7-guanine DNA-DNA cross-links in white blood cells of cancer patients receiving cyclophosphamide therapy

Analytical Chemistry

Volumn 82, Issue 9, 2010, Pages 3650-3658

  Malayappan, Bhaskar ^a   Johnson, L'aurelle ^a   Nie, Bei ^a   Panchal, Dolly ^a   Matter, Brock ^a   Jacobson, Pamala ^a   Tretyakova, Natalia ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENTS; BIOLOGICAL ACTIVITIES; CANCER CHEMOTHERAPY; CANCER PATIENTS; CAPILLARY HPLC; CYTOTOXIC; DNA REPAIR; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-ELECTROSPRAY IONIZATION TANDEM MASS SPECTROMETRY; HUMAN BLOODS; INTERNAL STANDARDS; ISOTOPE DILUTIONS; METABOLIC ACTIVATION; MONO-ADDUCTS; SELECTED REACTION MONITORING; SOLID-PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; THERMAL HYDROLYSIS; WHITE BLOOD CELLS;

BLOOD; CELL DEATH; CHEMOTHERAPY; CHROMATOGRAPHY; DNA; ELECTROSPRAY IONIZATION; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; IONIZATION; ISOTOPES; LIQUIDS; MASS SPECTROMETRY; ORGANIC COMPOUNDS; PARTICLE DETECTORS; POSITIVE IONS;

GENES;

ANTINEOPLASTIC AGENT; CROSS LINKING REAGENT; CYCLOPHOSPHAMIDE; DNA; GUANINE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LEUKOCYTE;

ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-LINKING REAGENTS; CYCLOPHOSPHAMIDE; DNA; GUANINE; HUMANS; LEUKOCYTES; MOLECULAR STRUCTURE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 77951779215     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac902923s     Document Type: Article

References (29)

1. Reece, D. E., Connors, J. M., Spinelli, J. J., Barnett, M. J., Fairey, R. N., Klingemann, H. G., Nantel, S. H., O'Reilly, S., Shepherd, J. D., and Sutherland, H. J. Blood 1994, 83, 1193-1199
2. Demirer, T., Buckner, C. D., Appelbaum, F. R., Bensinger, W. I., Sanders, J., Lambert, K., Clift, R., Fefer, A., Storb, R., and Slattery, J. T. Bone Marrow Transplant. 1996, 17, 491-495
3. Demirer, T., Buckner, C. D., Appelbaum, F. R., Clift, R., Storb, R., Myerson, D., Lilleby, K., Rowley, S., and Bensinger, W. I. Bone Marrow Transplant. 1996, 17, 769-774
4. Demirer, T., Buckner, C. D., Appelbaum, F. R., Lambert, K., Bensinger, W. I., Clift, R., Storb, R., and Slattery, J. T. Bone Marrow Transplant. 1996, 17, 341-346
5. Demirer, T., Weaver, C. H., Buckner, C. D., Petersen, F. B., Bensinger, W. I., Sanders, J., Clift, R. A., Lilleby, K., Anasetti, C., and Martin, P. J. Clin. Oncol. 1995, 13, 596-602
6. Sadagopan, N., Cohen, L., Roberts, B., Collard, W., and Omer, C. J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2001, 759, 277-284
7. Kalhorn, T. F., Howald, W. N., Cole, S., Phillips, B., Wang, J., Slattery, J. T., and McCune, J. S. J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2006, 835, 105-113
8. Connors, T. A., Foster, A. B., Gilsenan, A. M., Jarman, M., and Tisdale, M. J. Biochem. Pharmacol. 1972, 21, 1373-1376
9. Benson, A. J., Martin, C. N., and Garner, R. C. Biochem. Pharmacol. 1988, 37, 2979-2985
10. Hemminki, K. Chem. Biol. Interact. 1987, 61, 75-788
11. Hemminki, K. Cancer Res. 1985, 45, 4237-4243
12. Millard, J. T., Luedtke, N. W., and Spencer, R. J. Anti-Cancer Drug Des. 1996, 11, 485-492
13. Rajski, S. R. and Williams, R. M. Chem. Rev. 1998, 98, 2723-2796
14. Dong, Q., Barsky, D., Colvin, M. E., Melius, C. F., Ludeman, S. M., Moravek, J. F., Colvin, O. M., Bigner, D. D., Modrich, P., and Friedman, H. S. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 12170-12174
15. Souliotis, V. L., Dimopoulos, M. A., and Sfikakis, P. P. Clin. Cancer Res. 2003, 9, 4465-4474
16. Scharer, O. D. ChemBioChem 2005, 6, 27-32
17. Yabe, M., Yabe, H., Hamanoue, S., Inoue, H., Matsumoto, M., Koike, T., Ishiguro, H., Morimoto, T., Arakawa, S., Ohshima, T., Masukawa, A., Miyachi, H., Yamashita, T., and Katob, S. Int. J. Hematol. 2007, 85, 354-361
18. Thulin, H., Zorcec, V., Segerback, D., Sundwall, A., and Tornqvist, M. Chem. Biol. Interact. 1996, 99, 263-275
19. DeNeve, W., Valeriote, F., Edelstein, M., Everett, C., and Bischoff, M. Cancer Res. 1989, 49, 3452-3456
20. Van den Driessche, B., Lemiere, F., Witters, E., Van Dongen, W., and Esmans, E. L. Rapid Commun. Mass Spectrom. 2005, 19, 449-454
21. Baskerville-Abraham, I. M., Boysen, G., Troutman, J. M., Mutlu, E., Collins, L., Dekrafft, K. E., Lin, W., King, C., Chaney, S. G., and Swenberg, J. A. Chem. Res. Toxicol. 2009, 22, 905-912
22. Goggin, M., Loeber, R., Park, S., Walker, V., Wickliffe, J., and Tretyakova, N. Chem. Res. Toxicol. 2007, 20, 839-847
23. Goggin, M., Anderson, C., Park, S., Swenberg, J., Walker, V., and Tretyakova, N. Chem. Res. Toxicol. 2008, 21, 1163-1170
24. Goggin, M., Swenberg, J. A., Walker, V. E., and Tretyakova, N. Cancer Res. 2009, 69, 2479-2486
25. Koc, H. and Swenberg, J. A. J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2002, 778, 323-343
26. Farmer, P. B., Brown, K., Tompkins, E., Emms, V. L., Jones, D. J., Singh, R., and Phillips, D. H. Toxicol. Appl. Pharmacol. 2005, 207, 293-301
27. Brookes, P. and Lawley, P. D. Biochem. J. 1961, 80, 496-503
28. Cushnir, J. R., Naylor, S., Lamb, J. H., Farmer, P. B., Brown, N. A., and Mirkes, P. E. Rapid Commun. Mass Spectrom. 1990, 4, 410-414
29. Mirkes, P. E., Greenaway, J. C., Colvin, M., and Brundrett, R. B. Teratology 1982, 25, A63