메뉴 건너뛰기




Volumn 9, Issue 12, 2003, Pages 4465-4474

Gene-specific formation and repair of DNA monoadducts and interstrand cross-links after therapeutic exposure to nitrogen mustards

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; CHLORMETHINE DERIVATIVE; CYCLOPHOSPHAMIDE; MELPHALAN; ONCOPROTEIN; PROTEIN P53;

EID: 0141995075     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (41)

References (48)
  • 1
    • 0028943798 scopus 로고
    • Alkylation of DNA by the nitrogen mustard bis(2-chloroethyl)methylamine
    • Osborne, M. R., Wilman, D. E. V., and Lawley, P. D. Alkylation of DNA by the nitrogen mustard bis(2-chloroethyl)methylamine. Chem. Res. Toxicol., 2: 316-320, 1995.
    • (1995) Chem. Res. Toxicol. , vol.2 , pp. 316-320
    • Osborne, M.R.1    Wilman, D.E.V.2    Lawley, P.D.3
  • 2
    • 0002385099 scopus 로고
    • The alkylating agents
    • M. Chabner (ed.). Philadelphia: W. B. Saunders Co.
    • Colvin M. The alkylating agents. In: M. Chabner (ed.), Pharmacological Principles of Cancer Treatment, pp. 276-308. Philadelphia: W. B. Saunders Co., 1982.
    • (1982) Pharmacological Principles of Cancer Treatment , pp. 276-308
    • Colvin, M.1
  • 3
    • 0002469358 scopus 로고
    • Molecular mechanisms of crosslinking by alkylating agents and platinum complexes
    • A. C. Sartorelli, J. S. Lazlo, and J. R. Bertino (eds.). New York: Academic Press, Inc.
    • Kohn K. W. Molecular mechanisms of crosslinking by alkylating agents and platinum complexes. In: A. C. Sartorelli, J. S. Lazlo, and J. R. Bertino (eds.), Molecular Actions and Targets for Cancer Chemotherapy Agents, pp. 3-16. New York: Academic Press, Inc., 1981.
    • (1981) Molecular Actions and Targets for Cancer Chemotherapy Agents , pp. 3-16
    • Kohn, K.W.1
  • 4
    • 0032533515 scopus 로고    scopus 로고
    • Nucleotide excision repair of melphalan monoadducts
    • Grant, D. F., Bessho, T., and Reardon, J. T. Nucleotide excision repair of melphalan monoadducts. Cancer Res., 22: 5196-5200, 1998.
    • (1998) Cancer Res. , vol.22 , pp. 5196-5200
    • Grant, D.F.1    Bessho, T.2    Reardon, J.T.3
  • 5
    • 0029762815 scopus 로고    scopus 로고
    • DNA repair: Enzymatic mechanisms and relevance to drug response
    • Chaney, S. G., and Sancar A. DNA repair: enzymatic mechanisms and relevance to drug response. J. Natl. Cancer Inst., 19: 1346-1360, 1996.
    • (1996) J. Natl. Cancer Inst. , vol.19 , pp. 1346-1360
    • Chaney, S.G.1    Sancar, A.2
  • 6
    • 0035807079 scopus 로고    scopus 로고
    • Repair of DNA interstrand cross-links
    • Dronkert M. L., and Kanaar R. Repair of DNA interstrand cross-links. Mutat. Re., 486: 217-247, 2001.
    • (2001) Mutat. Res. , vol.486 , pp. 217-247
    • Dronkert, M.L.1    Kanaar, R.2
  • 7
    • 0000246061 scopus 로고
    • Cyclophosphamide and related phosphoramide mustards: Current status and future perspectives
    • A. Rosowsky (ed.), Advances in Cancer Chemotherapy. New York: Marcel Dekker, Inc.
    • Friedman O. M., Myles A., and Colvin M. Cyclophosphamide and related phosphoramide mustards: current status and future perspectives. In: A. Rosowsky (ed.), Advances in Cancer Chemotherapy, pp. 143-204. New York: Marcel Dekker, Inc., 1979.
    • (1979) Advances in Cancer Chemotherapy , pp. 143-204
    • Friedman, O.M.1    Myles, A.2    Colvin, M.3
  • 8
    • 0025869116 scopus 로고
    • Cyclophosphamide pulses in the treatment of rheumatic diseases: An update
    • De Vita, S., Neri, R., and Bombardieri, S. Cyclophosphamide pulses in the treatment of rheumatic diseases: an update. Clin. Exp. Rheumatol., 9: 179-193, 1991.
    • (1991) Clin. Exp. Rheumatol. , vol.9 , pp. 179-193
    • De Vita, S.1    Neri, R.2    Bombardieri, S.3
  • 9
    • 0024245628 scopus 로고
    • Acute nonlymphocytic leukemia following short-term, intermittent, intravenous cyclophosphamide treatment of lupus nephritis
    • Gibbons, R. B., and Westerman, E. Acute nonlymphocytic leukemia following short-term, intermittent, intravenous cyclophosphamide treatment of lupus nephritis. Arthritis Rheum., 31: 1552-1554, 1988.
    • (1988) Arthritis Rheum. , vol.31 , pp. 1552-1554
    • Gibbons, R.B.1    Westerman, E.2
  • 10
    • 0026599235 scopus 로고
    • Bladder cancer after cyclophosphamide therapy for lupus nephritis
    • Ortiz, A., Gonzalez-Parra, E., Aloarez-Costa, G., and Egido, J. Bladder cancer after cyclophosphamide therapy for lupus nephritis. Nephron. 60: 378-379, 1992.
    • (1992) Nephron. , vol.60 , pp. 378-379
    • Ortiz, A.1    Gonzalez-Parra, E.2    Aloarez-Costa, G.3    Egido, J.4
  • 11
    • 0015778791 scopus 로고
    • The relationship of the metabolism of anticancer agents to their activity
    • Montgomery, J. A., and Struck, R. F. The relationship of the metabolism of anticancer agents to their activity. Prog. Drug Res., 17: 320-409, 1973.
    • (1973) Prog. Drug Res. , vol.17 , pp. 320-409
    • Montgomery, J.A.1    Struck, R.F.2
  • 12
    • 0025974881 scopus 로고
    • A cyclophosphamide/DNA phosphoester adduct formed in vitro and in vivo
    • Maccubbin, A. E., Caballes, L., Riordan, J. M., Huang, D. H., and Gurtoo, H. L. A cyclophosphamide/DNA phosphoester adduct formed in vitro and in vivo. Cancer Res., 51: 886-892, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 886-892
    • Maccubbin, A.E.1    Caballes, L.2    Riordan, J.M.3    Huang, D.H.4    Gurtoo, H.L.5
  • 13
    • 0027514969 scopus 로고
    • Alkylation of DNA by melphalan and special reference to adenine derivatives and adenine-guanine cross-linking
    • Osborne, M. R., and Lawley, P. D. Alkylation of DNA by melphalan and special reference to adenine derivatives and adenine-guanine cross-linking. Chem.-Biol. Interact., 89: 49-60, 1993.
    • (1993) Chem.-Biol. Interact. , vol.89 , pp. 49-60
    • Osborne, M.R.1    Lawley, P.D.2
  • 15
    • 0028775544 scopus 로고
    • The treatment of multiple myeloma
    • Alexanian, R., and Dimopoulos, M. A. The treatment of multiple myeloma. N. Engl. J. Med., 330: 484-489, 1994.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 484-489
    • Alexanian, R.1    Dimopoulos, M.A.2
  • 16
    • 0025898481 scopus 로고
    • Heterogeneity of DNA repair at the gene level
    • Hanawalt, P. C. Heterogeneity of DNA repair at the gene level. Mutat. Res., 247: 203-211, 1991.
    • (1991) Mutat. Res. , vol.247 , pp. 203-211
    • Hanawalt, P.C.1
  • 17
    • 0025820176 scopus 로고
    • Hierarchies of DNA repair in mammalian cells: Biological consequences
    • Mullenders, L. H., Vrieling, H., Venema, J., and van Zeeland, A. A. Hierarchies of DNA repair in mammalian cells: biological consequences. Mutat. Res., 250: 223-228, 1991.
    • (1991) Mutat. Res. , vol.250 , pp. 223-228
    • Mullenders, L.H.1    Vrieling, H.2    Venema, J.3    Van Zeeland, A.A.4
  • 18
    • 0025091152 scopus 로고
    • Heterogeneity of nitrogen mustard-induced DNA damage and repair at the level of the gene in Chinese hamster ovary cells
    • Wassermann, K., Kohn, K. W., and Bohr, V. A. Heterogeneity of nitrogen mustard-induced DNA damage and repair at the level of the gene in Chinese hamster ovary cells. J. Biol. Chem., 265: 13906-13913, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 13906-13913
    • Wassermann, K.1    Kohn, K.W.2    Bohr, V.A.3
  • 21
    • 0030272439 scopus 로고    scopus 로고
    • Regulation of bcl-2 and fas expression in primary activation of human peripheral lymphocytes is not sensitive to dexamethasone or cyclosporin-A
    • Sfikakis, P. P., Souliotis, V. L., Akbar, A. N., Katsilambros, N., Hoffbrand, V. A., and Panayiotidis, P. Regulation of bcl-2 and fas expression in primary activation of human peripheral lymphocytes is not sensitive to dexamethasone or cyclosporin-A. Hum. Immunol., 50: 121-126, 1996.
    • (1996) Hum. Immunol. , vol.50 , pp. 121-126
    • Sfikakis, P.P.1    Souliotis, V.L.2    Akbar, A.N.3    Katsilambros, N.4    Hoffbrand, V.A.5    Panayiotidis, P.6
  • 22
    • 0032534709 scopus 로고    scopus 로고
    • Gene and human tumour cell line specific differences in nitrogen mustard induced DNA alkylation and interstrand crosslinking frequencies
    • Sunters, A., Grimaldi, K. A., Souhami, R. L., and Hartley, J. A. Gene and human tumour cell line specific differences in nitrogen mustard induced DNA alkylation and interstrand crosslinking frequencies. Nucleic Acids Res., 26: 5617-5623, 1998.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 5617-5623
    • Sunters, A.1    Grimaldi, K.A.2    Souhami, R.L.3    Hartley, J.A.4
  • 23
    • 0016700864 scopus 로고
    • Detection of specific sequences among DNA fragments separated by gel electrophoresis
    • Southern, E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol., 98: 503-517, 1975.
    • (1975) J. Mol. Biol. , vol.98 , pp. 503-517
    • Southern, E.M.1
  • 25
    • 0026500545 scopus 로고
    • Mutational activation of the N-ras oncogene assessed in primary clonogenic culture of acute myeloid leukemia (AML): Implications for the role of N-ras mutation in AML pathogenesis
    • Bashey, A., Gill, R., Levi, S., Farr, C. J., Clutterbuck, R., Millar, J. L., Pragnell, I. B., and Marshall, C. J. Mutational activation of the N-ras oncogene assessed in primary clonogenic culture of acute myeloid leukemia (AML): Implications for the role of N-ras mutation in AML pathogenesis. Blood, 79: 981-989, 1992.
    • (1992) Blood , vol.79 , pp. 981-989
    • Bashey, A.1    Gill, R.2    Levi, S.3    Farr, C.J.4    Clutterbuck, R.5    Millar, J.L.6    Pragnell, I.B.7    Marshall, C.J.8
  • 26
    • 0027411418 scopus 로고
    • Application of a sensitive immunoassay to the study of DNA adducts formed in peripheral blood mononuclear cells of patients undergoing high-dose melphalan therapy
    • Tilby, M. J., Mewell, D. R., Viner, C., Selby, P. J., and Deau C. J. Application of a sensitive immunoassay to the study of DNA adducts formed in peripheral blood mononuclear cells of patients undergoing high-dose melphalan therapy. Eur. J. Cancer, 29A: 681-686, 1993.
    • (1993) Eur. J. Cancer , vol.29 A , pp. 681-686
    • Tilby, M.J.1    Mewell, D.R.2    Viner, C.3    Selby, P.J.4    Deau, C.J.5
  • 27
    • 0014682978 scopus 로고
    • The response of mammalian cells to alkylating agents. II. On the mechanism of the removal of sulfur-mustard-induced cross-links
    • Reid, B. D., and Walker, I. G. The response of mammalian cells to alkylating agents. II. On the mechanism of the removal of sulfur-mustard-induced cross-links. Biochim. Biophys. Acta, 179: 179-188, 1968.
    • (1968) Biochim. Biophys. Acta , vol.179 , pp. 179-188
    • Reid, B.D.1    Walker, I.G.2
  • 28
    • 0023234707 scopus 로고
    • Formation and removal of DNA cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells
    • Hansson, J., Lewensohn, R., Ringborg, U., and Nilsson, B. Formation and removal of DNA cross-links induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells. Cancer Res., 47: 2631-2637, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 2631-2637
    • Hansson, J.1    Lewensohn, R.2    Ringborg, U.3    Nilsson, B.4
  • 29
    • 0018102806 scopus 로고
    • Differences between melphalan and nitrogen mustard in the formation and removal of DNA cross-links
    • Ross, W. E., Ewig, R. A., and Kohn, K. W. Differences between melphalan and nitrogen mustard in the formation and removal of DNA cross-links. Cancer Res., 38: 1502-1506, 1978.
    • (1978) Cancer Res. , vol.38 , pp. 1502-1506
    • Ross, W.E.1    Ewig, R.A.2    Kohn, K.W.3
  • 30
    • 0023942406 scopus 로고
    • Transport, metabolism, and DNA interaction of melphalan in lymphocytes from patients with chronic lymphocytic leukemia
    • Panasci, L., Henderson, D., Torres-Garcia, S. J., Skalski, V., Caplan, S., and Hutchins, M. Transport, metabolism, and DNA interaction of melphalan in lymphocytes from patients with chronic lymphocytic leukemia. Cancer Res., 48: 1972-1976, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 1972-1976
    • Panasci, L.1    Henderson, D.2    Torres-Garcia, S.J.3    Skalski, V.4    Caplan, S.5    Hutchins, M.6
  • 31
    • 0024470560 scopus 로고
    • Correlation of resistance to nitrogen mustards in chronic lymphocytic leukemia with enhanced removal of melphalan-induced DNA cross-links
    • Torres-Garcia, S. J., Cousineau, L., Caplan, S., and Panasci, L. Correlation of resistance to nitrogen mustards in chronic lymphocytic leukemia with enhanced removal of melphalan-induced DNA cross-links. Biochem. Pharmacol., 38: 3122-3123, 1989.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 3122-3123
    • Torres-Garcia, S.J.1    Cousineau, L.2    Caplan, S.3    Panasci, L.4
  • 32
    • 0026731906 scopus 로고
    • DNA strand breaks and DNA cross-links in peripheral mononuclear blood cells of ovarian cancer patients during chemotherapy with cyclophosphamide/carboplatin
    • Hengstler, J. G., Fuchs, J., and Oesch F. DNA strand breaks and DNA cross-links in peripheral mononuclear blood cells of ovarian cancer patients during chemotherapy with cyclophosphamide/carboplatin. Cancer Res., 52: 5622-5626, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 5622-5626
    • Hengstler, J.G.1    Fuchs, J.2    Oesch, F.3
  • 33
    • 0024312087 scopus 로고
    • In vivo DNA cross-linking by cyclophosphamide: Comparison of human chronic lymphatic leukemia cells with mouse L1210 leukemia and normal bone marrow cells
    • DeNeve, W., Valeriote, F., Edelstein, M., Everett, C., and Bischoff, M. In vivo DNA cross-linking by cyclophosphamide: comparison of human chronic lymphatic leukemia cells with mouse L1210 leukemia and normal bone marrow cells. Cancer Res., 49: 3452-3456, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 3452-3456
    • DeNeve, W.1    Valeriote, F.2    Edelstein, M.3    Everett, C.4    Bischoff, M.5
  • 35
    • 0022362337 scopus 로고    scopus 로고
    • Occurrence of second primary malignancies in man: A second outlook
    • Henne T., and Schmahl D. Occurrence of second primary malignancies in man: a second outlook. Cancer Treat. Rev., 12: 77-94
    • Cancer Treat. Rev. , vol.12 , pp. 77-94
    • Henne, T.1    Schmahl, D.2
  • 36
    • 0026500545 scopus 로고
    • Mutational activation of the N-ras oncogene assessed in primary clonogenic culture of acute myeloid leukemia (AML): Implications for the role of N-ras mutation in AML pathogenesis
    • Bashey, A., Gill, R., Levi, S., Farr, C. J., Clutterbuck, R., Millar, J. L., Pragnell, I. B., and Marshall, C. J. Mutational activation of the N-ras oncogene assessed in primary clonogenic culture of acute myeloid leukemia (AML): implications for the role of N-ras mutation in AML pathogenesis. Blood, 79: 981-989, 1992.
    • (1992) Blood , vol.79 , pp. 981-989
    • Bashey, A.1    Gill, R.2    Levi, S.3    Farr, C.J.4    Clutterbuck, R.5    Millar, J.L.6    Pragnell, I.B.7    Marshall, C.J.8
  • 37
    • 0029119506 scopus 로고
    • Products from alkylation of DNA in cells by melphalan: Human soft tissue sarcoma cell line RD and Escherichia coli WP2
    • Osborne, M. R., Lawley, P. D., Crofton-Sleigh, C., and Warren, W. Products from alkylation of DNA in cells by melphalan: human soft tissue sarcoma cell line RD and Escherichia coli WP2. Chem.-Biol. Interact., 97: 287-296, 1995.
    • (1995) Chem.-Biol. Interact. , vol.97 , pp. 287-296
    • Osborne, M.R.1    Lawley, P.D.2    Crofton-Sleigh, C.3    Warren, W.4
  • 38
    • 0025768599 scopus 로고
    • Cell cycle arrest and DNA damage after melphalan treatment of the human myeloma cell line RPMI 8226
    • Fernberg, J. O., Lewensohn, R., and Skog, S. Cell cycle arrest and DNA damage after melphalan treatment of the human myeloma cell line RPMI 8226. Eur. J. Haematol., 47: 161-167, 1991.
    • (1991) Eur. J. Haematol. , vol.47 , pp. 161-167
    • Fernberg, J.O.1    Lewensohn, R.2    Skog, S.3
  • 39
    • 0030591663 scopus 로고    scopus 로고
    • DNA adducts from chemotherapeutic agents
    • Lawley, P. D., and Phillips, D. H. DNA adducts from chemotherapeutic agents. Mutat. Res., 355: 13-40, 1996.
    • (1996) Mutat. Res. , vol.355 , pp. 13-40
    • Lawley, P.D.1    Phillips, D.H.2
  • 40
    • 0025284671 scopus 로고
    • Melphalan-induced DNA cross-linking and inhibition of DNA and RNA synthesis in human melanoma and lymphoblast cells
    • Ringborg, U., Hansson, J., Jungnelius, U., Lewensohn, R., and Skog, S. Melphalan-induced DNA cross-linking and inhibition of DNA and RNA synthesis in human melanoma and lymphoblast cells. Anticancer Res., 10: 297-301, 1990.
    • (1990) Anticancer Res. , vol.10 , pp. 297-301
    • Ringborg, U.1    Hansson, J.2    Jungnelius, U.3    Lewensohn, R.4    Skog, S.5
  • 41
    • 0034100766 scopus 로고    scopus 로고
    • DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts
    • Mu, D., Bessho, T., Nechev, L. V., Chen, D. J., Harris, T. M., Hearst, J. E., and Sancar A. DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts. Mol. Cell. Biol., 20: 2446-2454, 2000.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2446-2454
    • Mu, D.1    Bessho, T.2    Nechev, L.V.3    Chen, D.J.4    Harris, T.M.5    Hearst, J.E.6    Sancar, A.7
  • 42
    • 0021119161 scopus 로고
    • Direct cloning of human ovarian cancer in soft agar: Clinical limitations and pharmacologic applications
    • Ozols, R. F., Hogan, W. M., and Young, R. C. Direct cloning of human ovarian cancer in soft agar: clinical limitations and pharmacologic applications. Recent Results Cancer Res., 94: 41-50, 1984.
    • (1984) Recent Results Cancer Res. , vol.94 , pp. 41-50
    • Ozols, R.F.1    Hogan, W.M.2    Young, R.C.3
  • 43
    • 0021196394 scopus 로고
    • Biochemical short-term predictive assay: Results of correlative trials in comparison to other assays
    • Kaufmann, M. Biochemical short-term predictive assay: results of correlative trials in comparison to other assays. Recent Results Cancer Res., 94: 151-160, 1984.
    • (1984) Recent Results Cancer Res. , vol.94 , pp. 151-160
    • Kaufmann, M.1
  • 46
    • 0025601469 scopus 로고
    • Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy: Comparison with in vitro adduct formation
    • Fichtinger-Schepman, A. M., van der Velde-Visser, S. D., van Dijk-Knijnenburg, H. C., van Oosterom, A. T., Baan, R. A., and Berends, F. Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy: comparison with in vitro adduct formation. Cancer Res., 50: 7887-7894, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 7887-7894
    • Fichtinger-Schepman, A.M.1    Van der Velde-Visser, S.D.2    Van Dijk-Knijnenburg, H.C.3    Van Oosterom, A.T.4    Baan, R.A.5    Berends, F.6
  • 47
    • 0025799467 scopus 로고
    • Platinum-DNA damage in leukocyte DNA of patients receiving carboplatin and cisplatin chemotherapy, measured by atomic absorption spectrometry
    • Parker, R. J., Gill, I., Tarone, R., Vionnet, J. A., Grunberg, S., Muggia, F. M., and Reed, E. Platinum-DNA damage in leukocyte DNA of patients receiving carboplatin and cisplatin chemotherapy, measured by atomic absorption spectrometry. Carcinogenesis (Lond.), 12: 1253-1258, 1991.
    • (1991) Carcinogenesis (Lond.) , vol.12 , pp. 1253-1258
    • Parker, R.J.1    Gill, I.2    Tarone, R.3    Vionnet, J.A.4    Grunberg, S.5    Muggia, F.M.6    Reed, E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.