-
1
-
-
29244431680
-
Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis
-
Jansen M, de Leng WW, Baas AF, Myoshi H, Mathus-Vliegen L, Taketo MM, Clevers H, Giardiello FM and Offerhaus GJ: Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis. Gut 55: 1-5, 2006.
-
(2006)
Gut
, vol.55
, pp. 1-5
-
-
Jansen, M.1
De Leng, W.W.2
Baas, A.F.3
Myoshi, H.4
Mathus-Vliegen, L.5
Taketo, M.M.6
Clevers, H.7
Giardiello, F.M.8
Offerhaus, G.J.9
-
2
-
-
0033053940
-
The molecular basis and clinical aspects of Peutz-Jeghers syndrome
-
Hemminki A: The molecular basis and clinical aspects of Peutz-Jeghers syndrome. Cell Mol Life Sci 55: 735-750, 1999.
-
(1999)
Cell Mol Life Sci
, vol.55
, pp. 735-750
-
-
Hemminki, A.1
-
4
-
-
33744782567
-
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome
-
Hearle N, Schumacher V, Menko FH, et al: Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. Clin Cancer Res 12: 3209-3215, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3209-3215
-
-
Hearle, N.1
Schumacher, V.2
Menko, F.H.3
-
5
-
-
34347386038
-
Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome
-
Mehenni H, Resta N, Guanti G, Mota-Vieira L, Lerner A, Peyman M, Chong KA, Aissa L, Ince A, Cosme A, Costanza MC, Rossier C, Radhakrishna U, Burt RW and Picard D: Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome. Dig Dis Sci 52: 1924-1933, 2007.
-
(2007)
Dig Dis Sci
, vol.52
, pp. 1924-1933
-
-
Mehenni, H.1
Resta, N.2
Guanti, G.3
Mota-Vieira, L.4
Lerner, A.5
Peyman, M.6
Chong, K.A.7
Aissa, L.8
Ince, A.9
Cosme, A.10
Costanza, M.C.11
Rossier, C.12
Radhakrishna, U.13
Burt, R.W.14
Picard, D.15
-
6
-
-
0033923499
-
Genetic heterogeneity in Peutz-Jeghers syndrome
-
Boardman LA, Couch FJ, Burgart LJ, Schwartz D, Berry R, McDonnell SK, Schaid DJ, Hartmann LC, Schroeder JJ, Stratakis CA and Thibodeau SN: Genetic heterogeneity in Peutz-Jeghers syndrome. Hum Mutat 16: 23-30, 2000.
-
(2000)
Hum Mutat
, vol.16
, pp. 23-30
-
-
Boardman, L.A.1
Couch, F.J.2
Burgart, L.J.3
Schwartz, D.4
Berry, R.5
McDonnell, S.K.6
Schaid, D.J.7
Hartmann, L.C.8
Schroeder, J.J.9
Stratakis, C.A.10
Thibodeau, S.N.11
-
8
-
-
33749070180
-
Peutz-Jeghers syndrome: Clinicopathology and molecular alterations
-
McGarrity TJ and Amos C: Peutz-Jeghers syndrome: clinicopathology and molecular alterations. Cell Mol Life Sci 63: 2135-2144, 2006.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 2135-2144
-
-
McGarrity, T.J.1
Amos, C.2
-
9
-
-
11244300732
-
LKB1, the multitasking tumour suppressor kinase
-
Marignani PA: LKB1, the multitasking tumour suppressor kinase. J Clin Pathol 58: 15-19, 2005.
-
(2005)
J Clin Pathol
, vol.58
, pp. 15-19
-
-
Marignani, P.A.1
-
10
-
-
33947100984
-
Dysfunctional AMPK activity, signaling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer
-
Carretero J, Medina PP, Blanco R, Smit L, Tang M, Roncador G, Maestre L, Conde E, Lopez-Rios F, Clevers HC and Sanchez-Cespedes M: Dysfunctional AMPK activity, signaling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer. Oncogene 26: 1616-1625, 2007.
-
(2007)
Oncogene
, vol.26
, pp. 1616-1625
-
-
Carretero, J.1
Medina, P.P.2
Blanco, R.3
Smit, L.4
Tang, M.5
Roncador, G.6
Maestre, L.7
Conde, E.8
Lopez-Rios, F.9
Clevers, H.C.10
Sanchez-Cespedes, M.11
-
11
-
-
1542618348
-
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
-
Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA and Cantley LC: The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc Natl Acad Sci USA 101: 3329-3335, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3329-3335
-
-
Shaw, R.J.1
Kosmatka, M.2
Bardeesy, N.3
Hurley, R.L.4
Witters, L.A.5
DePinho, R.A.6
Cantley, L.C.7
-
12
-
-
44649195012
-
Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain
-
Mukherjee P, Mulrooney TJ, Marsh J, Blair D, Chiles TC and Seyfried TN: Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain. Mol Cancer 7: 37-52, 2008.
-
(2008)
Mol Cancer
, vol.7
, pp. 37-52
-
-
Mukherjee, P.1
Mulrooney, T.J.2
Marsh, J.3
Blair, D.4
Chiles, T.C.5
Seyfried, T.N.6
-
15
-
-
1642430935
-
Wnt breakers in colon cancer
-
Clevers H: Wnt breakers in colon cancer. Cancer Cell 5: 5-6, 2004.
-
(2004)
Cancer Cell
, vol.5
, pp. 5-6
-
-
Clevers, H.1
-
16
-
-
33847740988
-
Wnt/beta-catenin signaling in cancer stemness and malignant behavior
-
Fodde R and Brabletz T: Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol 19: 150-158, 2007.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 150-158
-
-
Fodde, R.1
Brabletz, T.2
-
17
-
-
33644542084
-
Identification of the IFITM family as a new molecular marker in human colorectal tumors
-
Andreu P, Colnot S, Godard C, Laurent-Puig P, Lamarque D, Kahn A, Perret C and Romagnolo B: Identification of the IFITM family as a new molecular marker in human colorectal tumors. Cancer Res 66: 1949-1955, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 1949-1955
-
-
Andreu, P.1
Colnot, S.2
Godard, C.3
Laurent-Puig, P.4
Lamarque, D.5
Kahn, A.6
Perret, C.7
Romagnolo, B.8
-
18
-
-
21244490466
-
Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos
-
Lickert H, Cox B, Wehrle C, Taketo MM, Kemler R and Rossant J: Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos. Development 132: 2599-2609, 2005.
-
(2005)
Development
, vol.132
, pp. 2599-2609
-
-
Lickert, H.1
Cox, B.2
Wehrle, C.3
Taketo, M.M.4
Kemler, R.5
Rossant, J.6
-
19
-
-
20144386624
-
The interferon-inducible 9-27 gene modulates the susceptibility to natural killer cells and the invasiveness of gastric cancer cells
-
Yang Y, Lee JH, Kim KY, Song HK, Kim JK, Yoon SR, Cho D, Song KS, Lee YH and Choi I: The interferon-inducible 9-27 gene modulates the susceptibility to natural killer cells and the invasiveness of gastric cancer cells. Cancer Lett 221: 191-200, 2005.
-
(2005)
Cancer Lett
, vol.221
, pp. 191-200
-
-
Yang, Y.1
Lee, J.H.2
Kim, K.Y.3
Song, H.K.4
Kim, J.K.5
Yoon, S.R.6
Cho, D.7
Song, K.S.8
Lee, Y.H.9
Choi, I.10
-
20
-
-
0033126055
-
Immunolocalization of beta catenin in intestinal polyps of Peutz-Jeghers and juvenile polyposis syndromes
-
Back W, Loff S, Jenne D and Bleyl U: Immunolocalization of beta catenin in intestinal polyps of Peutz-Jeghers and juvenile polyposis syndromes. J Clin Pathol 52: 345-349, 1999.
-
(1999)
J Clin Pathol
, vol.52
, pp. 345-349
-
-
Back, W.1
Loff, S.2
Jenne, D.3
Bleyl, U.4
-
21
-
-
0032976834
-
Intracellular distribution of beta-catenin in colorectal adenomas, carcinomas and Peutz-Jeghers polyps
-
Herter P, Kuhnen C, Müller KM, Wittinghofer A and Müller O: Intracellular distribution of beta-catenin in colorectal adenomas, carcinomas and Peutz-Jeghers polyps. J Cancer Res Clin Oncol 125: 297-304, 1999.
-
(1999)
J Cancer Res Clin Oncol
, vol.125
, pp. 297-304
-
-
Herter, P.1
Kuhnen, C.2
Müller, K.M.3
Wittinghofer, A.4
Müller, O.5
-
22
-
-
12444302178
-
Cyclooxygenase 2 expression and molecular alterations in Peutz-Jeghers hamartomas and carcinomas
-
De Leng WW, Westerman AM, Weterman MA, De Rooij FW, Dekken Hv H, De Goeij AF, Gruber SB, Wilson JH, Offerhaus GJ, Giardiello FM and Keller JJ: Cyclooxygenase 2 expression and molecular alterations in Peutz-Jeghers hamartomas and carcinomas. Clin Cancer Res 9: 3065-3072, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3065-3072
-
-
De Leng, W.W.1
Westerman, A.M.2
Weterman, M.A.3
De Rooij, F.W.4
Dekken Hv, H.5
De Goeij, A.F.6
Gruber, S.B.7
Wilson, J.H.8
Offerhaus, G.J.9
Giardiello, F.M.10
Keller, J.J.11
-
23
-
-
0034464147
-
Very high risk of cancer in familial Peutz-Jeghers syndrome
-
Giardiello FM, Brensinger JD, Tersmette AC, Goodman SN, Petersen GM, Booker SV, Cruz-Correa M and Offerhaus JA: Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology 119: 1447-1453, 2000.
-
(2000)
Gastroenterology
, vol.119
, pp. 1447-1453
-
-
Giardiello, F.M.1
Brensinger, J.D.2
Tersmette, A.C.3
Goodman, S.N.4
Petersen, G.M.5
Booker, S.V.6
Cruz-Correa, M.7
Offerhaus, J.A.8
-
24
-
-
0023192463
-
Increased risk of cancer in the Peutz-Jeghers syndrome
-
Giardiello FM, Welsh SB, Hamilton SR, Offerhaus GJ, Gittelsohn AM, Booker SV, Krush AJ, Yardley JH and Luk GD: Increased risk of cancer in the Peutz-Jeghers syndrome. N Engl J Med 316: 1511-1514, 1987.
-
(1987)
N Engl J Med
, vol.316
, pp. 1511-1514
-
-
Giardiello, F.M.1
Welsh, S.B.2
Hamilton, S.R.3
Offerhaus, G.J.4
Gittelsohn, A.M.5
Booker, S.V.6
Krush, A.J.7
Yardley, J.H.8
Luk, G.D.9
-
25
-
-
0042525904
-
LKB1 protein expression in the evolution of glandular neoplasia of the lung
-
Ghaffar H, Sahin F, Sanchez-Cepedes M, et al: LKB1 protein expression in the evolution of glandular neoplasia of the lung. Clin Cancer Res 9: 2998-3003, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2998-3003
-
-
Ghaffar, H.1
Sahin, F.2
Sanchez-Cepedes, M.3
-
26
-
-
58149166786
-
IFN-induced transmembrane protein 1 promotes invasion at early stage of head and neck cancer progression
-
Hatano H, Kudo Y, Ogawa I, Tsunematsu T, Kikuchi A, Abiko Y and Takata T: IFN-induced transmembrane protein 1 promotes invasion at early stage of head and neck cancer progression. Clin Cancer Res 14: 6097-6105, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6097-6105
-
-
Hatano, H.1
Kudo, Y.2
Ogawa, I.3
Tsunematsu, T.4
Kikuchi, A.5
Abiko, Y.6
Takata, T.7
-
27
-
-
0033663048
-
Cytoplasmic. beta-catenin accumulation as a predictor of hematogenous metastasis in human colorectal cancer
-
Maruyama K, Ochiai A, Akimoto S, Nakamura S, Baba S, Moriya Y and Hirohashi S: Cytoplasmic. beta-catenin accumulation as a predictor of hematogenous metastasis in human colorectal cancer. Oncology 59: 302-309, 2000.
-
(2000)
Oncology
, vol.59
, pp. 302-309
-
-
Maruyama, K.1
Ochiai, A.2
Akimoto, S.3
Nakamura, S.4
Baba, S.5
Moriya, Y.6
Hirohashi, S.7
-
28
-
-
0033771625
-
In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours
-
Rowan A, Churchman M, Jefferey R, Hanby A, Poulsom R and Tomlinson I: In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours. J Pathol 192: 203-206, 2000.
-
(2000)
J Pathol
, vol.192
, pp. 203-206
-
-
Rowan, A.1
Churchman, M.2
Jefferey, R.3
Hanby, A.4
Poulsom, R.5
Tomlinson, I.6
-
29
-
-
0344862109
-
Correlation of staging for LKB1 and Cox-2 in hamartomatous polyps and carcinoma from patients with Peutz-Jeghers syndrome
-
Wei C, Amos CI, Rashid A, Sabripour M, Nations L, McGarrity TJ and Frazier ML: Correlation of staging for LKB1 and Cox-2 in hamartomatous polyps and carcinoma from patients with Peutz-Jeghers syndrome. J Histochem Cytochem 51: 1665-1672, 2003.
-
(2003)
J Histochem Cytochem
, vol.51
, pp. 1665-1672
-
-
Wei, C.1
Amos, C.I.2
Rashid, A.3
Sabripour, M.4
Nations, L.5
McGarrity, T.J.6
Frazier, M.L.7
-
30
-
-
0034235011
-
Frequent β-catenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis
-
Yamada Y, Yoshimi N, Hirose Y, Kawabata K, et al: Frequent β-catenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis. Cancer Res 60: 3323-3327, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 3323-3327
-
-
Yamada, Y.1
Yoshimi, N.2
Hirose, Y.3
Kawabata, K.4
-
31
-
-
0037173081
-
Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon
-
Anderson CB, Neufeld KL and White RL: Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon. Proc Natl Acad Sci USA 99: 8683-8688, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8683-8688
-
-
Anderson, C.B.1
Neufeld, K.L.2
White, R.L.3
-
32
-
-
0035918538
-
Reduced membranous and ectopic cytoplasmic expression of beta-catenin correlate with cyclin D1 overexpression and poor prognosis in pancreatic cancer
-
Qiao Q, Ramadani M, Gansauge S, Gansauge F, Leder G and Beger HG: Reduced membranous and ectopic cytoplasmic expression of beta-catenin correlate with cyclin D1 overexpression and poor prognosis in pancreatic cancer. Int J Cancer 95: 194-197, 2001.
-
(2001)
Int J Cancer
, vol.95
, pp. 194-197
-
-
Qiao, Q.1
Ramadani, M.2
Gansauge, S.3
Gansauge, F.4
Leder, G.5
Beger, H.G.6
-
33
-
-
33746895756
-
Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer
-
Kudo Y, Ogawa I, Kitajima S, Kitagawa M, Kawai H, Gaffney PM, Miyauchi M and Takata T: Periostin promotes invasion and anchorage-independent growth in the metastatic process of head and neck cancer. Cancer Res 66: 6928-6935, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 6928-6935
-
-
Kudo, Y.1
Ogawa, I.2
Kitajima, S.3
Kitagawa, M.4
Kawai, H.5
Gaffney, P.M.6
Miyauchi, M.7
Takata, T.8
-
34
-
-
0033546695
-
Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patients
-
Nezu J, Oku A and Shimane M: Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patients. Biochem Biophys Res Commun 261: 750-755, 1999.
-
(1999)
Biochem Biophys Res Commun
, vol.261
, pp. 750-755
-
-
Nezu, J.1
Oku, A.2
Shimane, M.3
|