Differential antiapoptotic effect of erythropoietin on undifferentiated and retinoic acid-differentiated SH-SY5Y cells

Journal of Cellular Biochemistry

Volumn 110, Issue 1, 2010, Pages 151-161

  Wenker, Shirley D ^a,b   Chamorro, María E ^a   Vota, Daiana M ^a,b   Callero, Mariana A ^a,b   Vittori, Daniela C ^a,b   Nesse, Alcira B ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

All trans retinoic acid; Apoptosis; Differentiation; Erythropoietin; Erythropoietin receptor; Neuroprotection; SH SY5Y cells

Indexed keywords

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; RETINOIC ACID;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NERVE CELL; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL SURVIVAL; CYTOPROTECTION; DOWN-REGULATION; ERYTHROPOIETIN, RECOMBINANT; HUMANS; SIGNAL TRANSDUCTION; TRETINOIN;

ATRA;

EID: 77951742715     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22521     Document Type: Article

References (39)

1. Akhtar RS, Ness JM, Roth KA. 2004. Bcl-2 family regulation of neuronal development and neurodegeneration. Biochim Biophys Acta 1644:189-203. (Pubitemid 38281275)
2. Anagnostou A, Liu Z, Steiner M, Chin K, Lee ES, Kessimian N, Noguchi CT. 1994. Erythropoietin receptor mRNA expression in human endothelial cells. Proc Natl Acad Sci USA 91:3974-3978. (Pubitemid 24139555)
3. Arcasoy M, Jiang X, Haroon Z. 2003. Expression of erythropoietin receptor splice variants in human cancer. Biochem Biophys Res Commun 307:999-1007. (Pubitemid 36871672)
4. Benito A, Silva M, Grillot D, Núñez G, Fernández-Luna JL. 1996. Apoptosis induced by erythroid differentiation of human leukemia cell lines is inhibited by Bcl-xL. Blood 87:3837-3843. (Pubitemid 26129612)
5. Benn SC, Woolf CJ. 2004. Adult neuron survival strategies - Slamming on the brakes. Nat Rev Neurosci 5:686-700.
6. Buemi M, Cavallaro E, Floccari F, Sturiale A, Aloisi C, Trimarchi M, Grasso G, Corica F, Frisinas N. 2002. Erythropoietin and the brain: From neurodevelopment to neuroprotection. Clin Sci 103:275-282.
7. Celik M, Gökmen N, Erbayraktar M, Akhisaroglu M, Konakc S, Ulukus C, Genc S, Genc K, Sagiroglu E, Cerami A, Brines M. 2002. Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury. Proc Natl Acad Sci USA 99:2258-2263. (Pubitemid 34169048)
8. Choi WH, Ji KA, Jeon SB, Yang MS, Kim H, Min KJ, Shong M, Jou I, Joe EH. 2005. Anti-inflammatory roles of retinoic acid in rat brain astrocytes: Suppression of interferon-gamma-induced JAK/STAT phosphorylation. Biochem Biophys Res Commun 329:125-131. (Pubitemid 40255430)
9. Chong ZZ, Hang JQ, Maiese K. 2002. Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades. J Cereb Blood Flow Metab 22:503-514. (Pubitemid 34477771)
10. Encinas M, Iglesias M, Liu Y, Wang H, Muhaisen A, Ceña V, Gallego C. 2000. Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells. J Neurochem 75:991-1003. (Pubitemid 30660487)
11. Genc S, Koroglu TF, Genc K. 2004. Erythropoietin and the nervous system. Brain Res 1000:19-31.
12. Kalcheva N, Albala J, O'Guin K, Rubino H, Garner C, Shafit-Zagardo B. 1995. Genomic structure of human microtubule-associated protein 2 (MAP-2) and characterization of additional MAP-2 isoforms. Proc Natl Acad Sci USA 92(24):10894-10898.
13. Labbaye C, Valtieri M, Barberi T, Meccia E, Masella B, Pelosi E, Condorelli GL, Testa U, Peschle C. 1995. Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis. J Clin Invest 95:2346-2358.
14. Lasorella A, Iavarone A, Israel MA. 1995. Differentiation of neuroblastoma enhances Bcl-2 expression and induces alterations of apoptosis and drug resistance. Cancer Res 55:4711-4716.
15. Lombet A, Zujovic V, Kandouz M, Billardon C, Carvajal-Gonzalez S, Gompel A, Rostène W. 2001. Resistance to induced apoptosis in the human neuroblastoma cell line SK-N-SH in relation to neuronal differentiation. Role of Bcl-2 protein family. Eur J Biochem 268:1352-1362. (Pubitemid 32231888)
16. Lopez-Carballo G, Moreno L, Masiá S, Perez P, Barettino D. 2002. Activation of the phosphatidylinositol 3-kinase/Akt signaling pathway by retinoic acid is required for neural differentiation of SH-SY5Y human neuroblastoma cells. J Biol Chem 277:297-304.
17. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275.
18. Maiese K, Li F, Chong ZZ. 2005. New avenues of exploration for erythropoietin. JAMA 293:90-95.
19. Marti HH, Bernaudin M, Petit E, Bauer C. 2000. Neuroprotection and angiogenesis: Dual role of erythropoietin in brain ischemia. News Physiol Sci 15:225-229.
20. Masuda S, Nagao M, Takahata K, Konishi Y, Gallyas F, Tabira T, Sasaki R. 1993. Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells. J Biol Chem 268:11208-11216. (Pubitemid 23162313)
21. McKinney M, Robbins M. 1992. Chronic atropine administration up-regulates rat cortical muscarinic m1 receptor mRNA molecules: Assessment with the RT/PCR. Brain Res Mol Res 12:39-45.
22. Meijering E, Jacob M, Sarria JC, Steiner P, Hirling H, Unser M. 2004. Design and validation of a tool for neurite tracing and analysis in fluorescent microscopy images. Cytometry A 58:167-176. (Pubitemid 38509178)
23. Messi E, Florian MC, Caccia C, Zanisi M, Maggi R. 2008. Retinoic acid reduces human neuroblastoma cell migration and invasiveness: Effects on DCX, LIS1, neurofilaments-68 and vimentin expression. BMC Cancer 8:30. (Pubitemid 351314954)
24. Nagy L, Thomázy VA, Shipley GL, Fésüs L, Lamph W, Heyman RA, Chandraratna RA, Davies PJ. 1995. Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Mol Cell Biol 15:3540-3551.
25. Niizuma H, Nakamura Y, Ozaki T, Nakanishi H, Ohira M, Isogai E, Kageyama H, Imaizumi M, Nakagawara A. 2006. Bcl-2 is a key regulator for the retinoic acid-induced apoptotic cell death in neuroblastoma. Oncogene 25:5046-5055. (Pubitemid 44246363)
26. Noguchi CT, Asavaritikrai P, Teng R, Jia Y. 2007. Role of erythropoietin in the brain. Crit Rev Oncol Hematol 64:159-171.
27. Okazawa H, Shimizu J, Kamei M, Imafuku I, Hamada H, Kanazawa I. 1996. Bcl-2 inhibits retinoic acid-induced apoptosis during the neural differentiation of embryonal stem cells. J Cell Biol 132:955-968. (Pubitemid 26085509)
28. Paterno GD, Gillespie LL, Julien JP, Skup D. 1997. Regulation of neurofilament L, M and H gene expression during retinoic acid-induced neural differentiation of P19 embryonal carcinoma cells. Brain Res Mol Brain Res 49:247-254. (Pubitemid 27453135)
29. Pregi N, Vittori D, Perez G, Pérez Leirós C, Nesse A. 2006. Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells. Biochim Biophys Acta 1763:238-246.
30. Pregi N, Wenker S, Vittori D, Pérez Leirós C, Nesse A. 2009. TNF-alpha-induced apoptosis is prevented by erythropoietin treatment on SH-SY5Y cells. Exp Cell Res 315:419-431.
31. Prince JA, Oreland L. 1997. Staurosporine differentiated human SH-SY5Y neuroblastoma cultures exhibit transient apoptosis and trophic factor independence. Brain Res Bull 43:515-523. (Pubitemid 27324085)
32. Ronca F, Yee K, Yu V. 1999. Retinoic acid confers resistance to p53-dependent apoptosis in SH-SY5Y neuroblastoma cells by modulating nuclear import of p53. J Biol Chem 274:18128-18134. (Pubitemid 129519182)
33. Silva M, Grillot D, Benito A, Richard C, Núñez G, Fernández-Luna JL. 1996. Erythropoietin can promote erythroid progenitor survival by repressing apoptosis through Bcl-xL and Bcl-2. Blood 88:1576-1582. (Pubitemid 26307051)
34. Sola A, Rogido M, Lee BH, Genetta T, Wen TC. 2005. Erythropoietin alter focal cerebral ischemia activates the Janus kinase-signal transducer and activator of transcription signaling pathway and improves brain injury in postnatal day 7 rats. Pediatr Res 57:481-487. (Pubitemid 40389334)
35. Tieu K, Zuo DM, Yu PH. 1999. Differential effects of staurosporine and retinoic acid on the vulnerability of the SH-SY5Y neuroblastoma cells: Involvement of Bcl-2 and p53 proteins. J Neurosci Res 58:426-435. (Pubitemid 29508576)
36. Um M, Lodish HF. 2006. Antiapoptotic effects of erythropoietin in differentiated neuroblastoma SH-SY5Y cells require activation of both the STAT5 and AKT signalling pathways. J Biol Chem 281:5648-5656. (Pubitemid 43847662)
37. Vittori D, Nesse A, Pérez G, Garbossa G. 1999. Morphological and functional alterations of erythroid cells induced by long-term ingestion of aluminium. J Inorg Biochem 76:113-120.
38. Yuste V, Sánchez-López I, Solé C, Encinas M, Bayascas J, Boix J, Comella J. 2002. The prevention of the staurosporine-induced apoptosis by Bcl-xL, but not by Bcl-2 or caspase inhibitors, allows the extensive differentiation of human neuroblastoma cells. J Neurochem 80:126-139. (Pubitemid 34614585)
39. Zhang KZ, Westberg JA, Hölttä E, Andersson LC. 1996. BCL2 regulates neural differentiation. Proc Natl Acad Sci USA 93:4504-4508.