T-lymphocyte-induced, fas-mediated apoptosis is associated with early keratinocyte differentiation

Experimental Dermatology

Volumn 19, Issue 4, 2010, Pages 372-380

  Daehn, Ilse S ^a,b   Varelias, Antiopi ^a   Rayner, Timothy E ^a,b  

^a WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

Author keywords

Apoptosis; Cytokine; Differentiation; Fas; Keratinocyte

Indexed keywords

ALPHA6 INTEGRIN; CASPASE 3; FAS ANTIGEN; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL INTERACTION; COCULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; PROTEIN EXPRESSION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; APOPTOSIS; CASPASE 3; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINE, TRANSFORMED; CELLS, CULTURED; COCULTURE TECHNIQUES; CYSTEINE PROTEINASE INHIBITORS; FAS LIGAND PROTEIN; HUMANS; INTEGRIN ALPHA6; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON-GAMMA; IONOMYCIN; KERATIN-10; KERATINOCYTES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; OLIGOPEPTIDES; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN PRECURSORS; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77951717345     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2009.00917.x     Document Type: Article

References (41)

1. Trautmann A, Akdis M, Kleemann D. T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis. J Clin Invest 2000, 106:25-35.
2. Sayama K, Yonehara S, Watanabe Y, Miki Y. Expression of Fas antigen on keratinocytes in vivo and induction of apoptosis in cultured keratinocytes. J Invest Dermatol 1994, 103:330-334.
3. Akdis C A, Akdis M, Trautmann A, Blaser K. Immune regulation in atopic dermatitis. Curr Opin Immunol 2000, 12:641-646.
4. Thepen T, Langeveld-Wildschut E G, Bihari I C. Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: an immunocytochemical study. J Allergy Clin Immunol 1996, 97:828-837.
5. Konur A, Schulz U, Eissner G, Andreesen R, Holler E. Interferon (IFN)-gamma is a main mediator of keratinocyte (HaCaT) apoptosis and contributes to autocrine IFN-gamma and tumour necrosis factor-alpha production. Br J Dermatol 2005, 152:1134-1142.
6. de Vries I J, Langeveld-Wildschut E G, van Reijsen F C. Adhesion molecule expression on skin endothelia in atopic dermatitis: effects of TNF-alpha and IL-4. J Allergy Clin Immunol 1998, 102:461-468.
7. Sesto A, Navarro M, Burslem F, Jorcano J L. Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays. Proc Natl Acad Sci U S A 2002, 99:2965-2970.
8. Krengel S, Stark I, Geuchen C. Selective down-regulation of the alpha6-integrin subunit in melanocytes by UVB light. Exp Dermatol 2005, 14:411-419.
9. Adams J C, Watt F M. Regulation of development and differentiation by the extracellular matrix. Development 1993, 117:1183-1198.
10. Webb A, Li A, Kaur P. Location and phenotype of human adult keratinocyte stem cells of the skin. Differentiation 2004, 72:387-395.
11. Boukamp P, Petrussevska R T, Breitkreutz D, Hornung J, Markham A, Fusenig N E. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 1988, 106:761-771.
12. Fadok V A, Voelker D R, Campbell P A, Cohen J J, Bratton D L, Henson P M. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 1992, 148:2207-2216.
13. Koopman G, Reutelingsperger C P, Kuijten G A, Keehnen R M, Pals S T, van Oers M H. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 1994, 84:1415-1420.
14. Daehn I S, Varelias A, Rayner T E. Sodium butyrate induced keratinocyte apoptosis. Apoptosis 2006, 11:1379-1390.
15. Hong S J, Dawson T M, Dawson V L. Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. Trends Pharmacol Sci 2004, 25:259-264.
16. Nickoloff B J, Mitra R S, Green J. Accessory cell function of keratinocytes for superantigens. Dependence on lymphocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. J Immunol 1993, 150:2148-2159.
17. Schoop V M, Mirancea N, Fusenig N E. Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts. J Invest Dermatol 1999, 112:343-353.
18. Boelsma E, Verhoeven M C, Ponec M. Reconstruction of a human skin equivalent using a spontaneously transformed keratinocyte cell line (HaCaT). J Invest Dermatol 1999, 112:489-498.
19. Lehman T A, Modali R, Boukamp P. p53 mutations in human immortalized epithelial cell lines. Carcinogenesis 1993, 14:833-839.
20. Chaturvedi V, Qin J Z, Denning M F, Choubey D, Diaz M O, Nickoloff B J. Apoptosis in proliferating, senescent, and immortalized keratinocytes. J Biol Chem 1999, 274:23358-23367.
21. Chaturvedi V, Qin J Z, Denning M F, Choubey D, Diaz M O, Nickoloff B J. Abnormal NF-kappaB signaling pathway with enhanced susceptibility to apoptosis in immortalized keratinocytes. J Dermatol Sci 2001, 26:67-78.
22. Qin J Z, Chaturvedi V, Denning M F, Choubey D, Diaz M O, Nickoloff B J. Role of NF-kappaB in the apoptotic-resistant phenotype of keratinocytes. J Biol Chem 1999, 274:37957-37964.
23. Spergel J M, Mizoguchi E, Oettgen H, Bhan A K, Geha R S. Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis. J Clin Invest 1999, 103:1103-1111.
24. Li A, Simmons P J, Kaur P. Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype. Proc Natl Acad Sci U S A 1998, 95:3902-3907.
25. Kaur P, Li A. Adhesive properties of human basal epidermal cells: an analysis of keratinocyte stem cells, transit amplifying cells, and postmitotic differentiating cells. J Invest Dermatol 2000, 114:413-420.
26. DiPersio C M, van der Neut R, Georges-Labouesse E, Kreidberg J A, Sonnenberg A, Hynes R O. alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development. J Cell Sci 2000, 113(Pt 17):3051-3062.
27. Saunders N A, Jetten A M. Control of growth regulatory and differentiation-specific genes in human epidermal keratinocytes by interferon gamma. Antagonism by retinoic acid and transforming growth factor beta 1. J Biol Chem 1994, 269:2016-2022.
28. Gandarillas A, Goldsmith L A, Gschmeissner S, Leigh I M, Watt F M. Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes. Exp Dermatol 1999, 8:71-79.
29. Norris D A. Differential control of cell death in the skin. Arch Dermatol 1995, 131:945-948.
30. Armbruster N, Trautmann A, Brocker E B, Leverkus M, Kerstan A. Suprabasal spongiosis in acute eczematous dermatitis: cFLIP maintains resistance of basal keratinocytes to T-cell-mediated apoptosis. J Invest Dermatol 2009, 129:1696-1702.
31. Dowling J, Yu Q C, Fuchs E. Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival. J Cell Biol 1996, 134:559-572.
32. Norris D A, Middleton M H, Whang K. Human keratinocytes maintain reversible anti-apoptotic defenses in vivo and in vitro. Apoptosis 1997, 2:136-148.
33. Howlett A R, Bailey N, Damsky C, Petersen O W, Bissell M J. Cellular growth and survival are mediated by beta 1 integrins in normal human breast epithelium but not in breast carcinoma. J Cell Sci 1995, 108(Pt 5):1945-1957.
34. Le Bellego F, Fabre S, Pisselet C, Monniaux D. Cytoskeleton reorganization mediates alpha6beta1 integrin-associated actions of laminin on proliferation and survival, but not on steroidogenesis of ovine granulosa cells. Reprod Biol Endocrinol 2005, 3:19.
35. Ryan M C, Lee K, Miyashita Y, Carter W G. Targeted disruption of the LAMA3 gene in mice reveals abnormalities in survival and late stage differentiation of epithelial cells. J Cell Biol 1999, 145:1309-1323.
36. Farrelly N, Lee Y J, Oliver J, Dive C, Streuli C H. Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling. J Cell Biol 1999, 144:1337-1348.
37. Pullan S, Wilson J, Metcalfe A. Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium. J Cell Sci 1996, 109(Pt 3):631-642.
38. Larjava H, Salo T, Haapasalmi K, Kramer R H, Heino J. Expression of integrins and basement membrane components by wound keratinocytes. J Clin Invest 1993, 92:1425-1435.
39. Nickoloff B J, Mitra R S, Riser B L, Dixit V M, Varani J. Modulation of keratinocyte motility. Correlation with production of extracellular matrix molecules in response to growth promoting and antiproliferative factors. Am J Pathol 1988, 132:543-551.
40. Eberle J, Fecker L F, Hossini A M, Kurbanov B M, Fechner H. Apoptosis pathways and oncolytic adenoviral vectors: promising targets and tools to overcome therapy resistance of malignant melanoma. Exp Dermatol 2008, 17:1-11.
41. Andjilani M, Droz J P, Benahmed M, Tabone E. Alpha6 integrin subunit mediates laminin enhancement of cisplatin-induced apoptosis in testicular tumor germ cells. Int J Cancer 2005, 117:68-81.