Mechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of iks

Journal of General Physiology

Volumn 135, Issue 5, 2010, Pages 433-448

  Eldstrom, Jodene ^a   Xu, Hongjian ^a   Werry, Daniel ^a   Kang, Congbao ^c   Loewen, Matthew E ^a   Degenhardt, Amanda ^a   Sanatani, Shubhayan ^b   Tibbits, Glen F ^d   Sanders, Charles ^c   Fedida, David ^a  

^a Department of Anesthesiology Pharmacology and Therapeutics   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c VANDERBILT UNIVERSITY   (United States)

^d SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

LTK PROTEIN, MOUSE; POTASSIUM CHANNEL KCNQ1; PROTEIN TYROSINE KINASE;

ACTION POTENTIAL; ANIMAL; ANIMAL MODEL; ARTICLE; CELL LINE; CHANNEL GATING; CHEMISTRY; CYTOLOGY; FIBROBLAST; GENETIC TRANSFECTION; GENETICS; HUMAN; LONG QT SYNDROME; MISSENSE MUTATION; MOUSE; PATCH CLAMP; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ACTION POTENTIALS; ANIMALS; CELL LINE; FIBROBLASTS; HUMANS; ION CHANNEL GATING; KCNQ1 POTASSIUM CHANNEL; LONG QT SYNDROME; MICE; MODELS, ANIMAL; MUTATION, MISSENSE; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; RECEPTOR PROTEIN-TYROSINE KINASES; TRANSFECTION;

EID: 77951713635     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.200910351     Document Type: Article

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